abstract：:Hepatocellular carcinoma (HCC) is the most common primary liver neoplasm and one of the most common causes of death in patients with cirrhosis of the liver. In parallel, with recognition of the clinical relevance of this cancer, major new developments have recently appeared in its diagnosis, prognostic assessment and ...

journal_title：Medicina clinica

authors： Reig M,Forner A,Ávila MA,Ayuso C,Mínguez B,Varela M,Bilbao I,Bilbao JI,Burrel M,Bustamante J,Ferrer J,Gómez MÁ,Llovet JM,De la Mata M,Matilla A,Pardo F,Pastrana MA,Rodríguez-Perálvarez M,Tabernero J,Urbano J,Vera

更新日期：2021-01-15 00:00:00

abstract：OBJECTIVE:In December 2019, Wuhan, China, experienced an outbreak of coronavirus disease 2019 (COVID-19). Some patients admitted to our hospital were treated with early prone positioning (PP). Here, we analyzed its clinical significance. METHODS:This was a retrospective observational study. We defined the early PP gro...

journal_title：Medicina clinica

authors： Liu X,Liu H,Lan Q,Zheng X,Duan J,Zeng F

更新日期：2020-12-26 00:00:00

abstract：BACKGROUND:In the context of the COVID-19 pandemic the risk of misdiagnosis of other causes of respiratory infection is likely. In this work we aim to describe the clinical characteristics, treatment and outcome of pneumococcal infection in COVID-19 patients. PATIENTS AND METHODS:Every COVID-19 patient presenting with...

journal_title：Medicina clinica

authors： Cucchiari D,Pericàs JM,Riera J,Gumucio R,Md EC,Nicolás D,Hospital Clínic 4H Team.

更新日期：2020-12-11 00:00:00

abstract：INTRODUCTION:Hypertension has been associated with worse outcomes in patients with COVID-19 infection, so concerns have been raised about the possibility that inhibitors of the renin-angiotensin system (RAS) could influence the prognosis of these patients. METHODS:This is an observational study of 921 consecutive pati...

journal_title：Medicina clinica

authors： Martínez-Del Río J,Piqueras-Flores J,Nieto-Sandoval Martín de la Sierra P,Negreira-Caamaño M,Águila-Gordo D,Mateo-Gómez C,Salas-Bravo D,Rodríguez-Martínez M

更新日期：2020-12-11 00:00:00

abstract：INTRODUCTION/OBJECTIVES:To describe the clinical, radiological and microbiological characteristics of vertebral osteomyelitis patients, analysing the factors that played a role on their outcome. PATIENTS AND METHODS:Single-centre retrospective observational study including patients diagnosed with vertebral osteomyelit...

journal_title：Medicina clinica

authors： Fragío Gil JJ,González Mazarío R,Salavert Lleti M,Román Ivorra JA

更新日期：2020-10-23 00:00:00

abstract：BACKGROUND:Elevated blood urea nitrogen to serum albumin (BUN/ALB) ratio had been identified as an independent risk factor related to mortality in community-acquired and hospital-acquired pneumonia. This study aimed to investigate whether this clinical index can predict the clinical outcomes of E. coli bacteraemia. MA...

journal_title：Medicina clinica

authors： Zou XL,Feng DY,Wu WB,Yang HL,Zhang TT

更新日期：2020-10-12 00:00:00

abstract：INTRODUCTION:Neurosarcoidosis is a rare complication of sarcoidosis. There are small series on the condition and very few from Spain. We conducted a retrospective study of neurosarcoidosis in Virgen de la Victoria Hospital over the last 10 years. PATIENTS AND METHOD:the medical records of patients diagnosed with sarco...

journal_title：Medicina clinica

authors： Carazo Barrios L,Abarca Costalago M,Hidalgo Conde A,Arnedo Díez de Los Ríos R,García Portales R,García Martín G

更新日期：2020-10-09 00:00:00

abstract：INTRODUCTION AND OBJECTIVES:Common laboratory parameters are crucial in aiding coronavirus disease 2019 (COVID-19) case detection. This study aimed to determine the differences between laboratory parameters in (1) COVID-19 versus non-COVID-19 pneumonia, and (2) severe versus non-severe COVID-19 cases. METHODS:Studies ...

journal_title：Medicina clinica

authors： Soraya GV,Ulhaq ZS

更新日期：2020-08-28 00:00:00

abstract：:Urinary tract infections are highly prevalent among women and when they are recurrent they can lead to patient discomfort and high healthcare costs, and they represent one of the most frequent causes of antibiotic consumption. There are several options to prevent RUTI which include both antibiotic treatment (continuou...

journal_title：Medicina clinica

authors： Pigrau C,Escolà-Vergé L

更新日期：2020-08-28 00:00:00

abstract：BACKGROUND AND OBJECTIVES:To compare the efficacy of a self-monitoring programme vs. the conventional method used before the intervention in maintaining the international normalised ratio (INR) in the therapeutic range in patients receiving oral anticoagulants, as well as complications, quality of life and the time inv...

journal_title：Medicina clinica

authors： Vall Vargas A,Altes Hernandez A,Arnau A,Constans Cots M,Gallart Fernández-Puebla A,de Juan Pardo MÁ

更新日期：2020-05-22 00:00:00

abstract：OBJECTIVE:To determine if a more simplified medication regimen is associated with survival in polypathological patients. METHODS:Multicentre cohort study. We included polypathological patients admitted to internal medicine wards between March 1st and June 30rd, 2011. Patients that died during admission and readmission...

journal_title：Medicina clinica

authors： Díez-Manglano J,Bellostas Muñoz L

更新日期：2020-04-10 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To analyse articles retracted due to irregularities by authors helps to determine the state of scientific integrity of a discipline or country. The Retraction Watch (RW) database is the largest worldwide database on retracted articles. The objective was to determine the reasons for and features...

journal_title：Medicina clinica

authors： Dal-Ré R

更新日期：2020-02-28 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Sporadic inclusion body myositis (sIBM) diagnosis is frequently delayed or confused with another class of disorders, and misdiagnosis is common. Sometimes, we have problems diagnosing an sIBM in the early stages or predicting when a PM is going to become an sIBM. In this sense, we believe that...

journal_title：Medicina clinica

authors： Milisenda JC,García AM,Jou C,Pinal-Fernandez I,O'Callaghan AS,Grau JM

更新日期：2019-12-13 00:00:00

abstract：INTRODUCTION:There are gaps in our knowledge of the normative levels of haemoglobin and the prevalence of anaemia in our geographical area, and in certain population subgroups. OBJECTIVES:To study the mean values of haemoglobin in a mountainous Spanish region, according to sex, age range and residence altitude, and th...

journal_title：Medicina clinica

authors： García-Erce JA,Lorente-Aznar T,Rivilla-Marugán L

更新日期：2019-12-13 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To assess the usefulness of a risk scale based on serum procalcitonin (PCT) compared to the Laboratory Risk Indicator for Necrotising Fasciitis (LRINEC) scale in the early discrimination between necrotising fasciitis (NF) and cellulitis of the extremities. MATERIALS AND METHODS:Retrospective s...

journal_title：Medicina clinica

authors： Novoa-Parra CD,Wadhwani J,Puig-Conca MA,Lizaur-Utrilla A,Montaner-Alonso D,Rodrigo-Pérez JL,Morales-Suárez-Varela M

更新日期：2019-11-15 00:00:00

abstract：BACKGROUND/OBJECTIVES:To assess the adherence to reporting confidence intervals (CI) for measures of association in multivariable regression models (MRM) in articles with observational design indexed in MEDLINE. MATERIAL AND METHODS:A literature search was conducted using the MEDLINE bibliographic database to obtain a...

journal_title：Medicina clinica

authors： González-Marrón A,Real J,Forné C,Roso-Llorach A,Navarrete-Muñoz EM,Martínez-Sánchez JM

更新日期：2019-09-27 00:00:00

abstract：INTRODUCTION:a description of infective left endocarditis at the turn of the millennium. METHOD:A multicentre prospective study into the left endocarditis using data collected from the Andalusian cohort for the study of cardiovascular infections during 1984-2014. RESULTS:Of the 1,604 endocarditis cases collected, 382...

journal_title：Medicina clinica

authors： Noureddine-López M,de la Torre-Lima J,Ruiz-Morales J,Gálvez-Acebal J,Hidalgo-Tenorio C,de Alarcón González CA,por el Grupo para el Estudio de las Infecciones Cardiovasculares de la Sociedad Andaluza de Enfermedades Infecciosas (SAEI).

更新日期：2019-07-19 00:00:00

abstract：OBJECTIVE:To compare the occurrence of haemorrhages among the different oral anticoagulants (OAC) and to analyse factors that influence it. MATERIAL AND METHODS:Single-centre, observational, retrospective study. After studying the total population treated with OAC, patients who were treated with an OAC from July 2015 ...

journal_title：Medicina clinica

authors： Gassó Sánchez A,Real Campaña JM,Franco Sorolla JM,Povar Marco BJ,Abad Sazatornil MR

更新日期：2019-06-21 00:00:00

abstract：BACKGROUND AND OBJECTIVE:In recent years, many studies have investigated metformin and its effects on lung cancer. However, since previous studies have shown that the relationship between metformin and lung cancer is complicated, we performed a meta-analysis to analyze this relationship. MATERIAL AND METHODS:An electr...

journal_title：Medicina clinica

authors： Zeng S,Gan HX,Xu JX,Liu JY

更新日期：2019-04-18 00:00:00

abstract：:Chronic kidney disease is common in people >65years of age. The development and improvement of dialysis techniques has allowed its generalisation to the entire population, when there is a situation of terminal nephropathy, without limit of use due to chronological age. Decision making in elderly patients with advanced...

journal_title：Medicina clinica

authors： Heras Benito M,Fernández-Reyes Luis MJ

更新日期：2019-03-01 00:00:00

abstract：INTRODUCTION AND OBJECTIVE:Hippotherapy is being used as a promising method in the physical treatment of multiple sclerosis (MS). MATERIAL AND METHOD:Comparative open clinical pre-post study into hippotherapy intervention during a 6-month period in patients with MS (n=6). Not randomised and with control group (n=4). T...

journal_title：Medicina clinica

authors： Muñoz-Lasa S,López de Silanes C,Atín-Arratibel MÁ,Bravo-Llatas C,Pastor-Jimeno S,Máximo-Bocanegra N

更新日期：2019-01-18 00:00:00

abstract：INTRODUCTION AND OBJECTIVE:Epicardial fat has been associated with increased cardiovascular risk and the development of atherosclerosis. Transthoracic echocardiography provides a reliable measurement of epicardial fat thickness (EFT). The aim of this study is to evaluate the relationship between EFT and biochemical par...

journal_title：Medicina clinica

authors： Rubio-Guerra AF,Benítez-Maldonado DR,Lozano-Nuevo JJ,Arana-Pazos KC,Huerta-Ramirez S,Narváez-Rivera JL

更新日期：2018-09-21 00:00:00

abstract：:Vitamin K antagonists were the only choice for chronic oral anticoagulation for more than half a century. Over the past few years, direct oral anticoagulants have emerged, including one direct thrombin inhibitor (dabigatran etexilate) and three factor Xa inhibitors (apixaban, edoxaban and rivaroxaban). In randomised c...

journal_title：Medicina clinica

authors： Franco Moreno AI,Martín Díaz RM,García Navarro MJ

更新日期：2018-09-14 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To determine the accuracy of clinical gestalt to identify patients with acute symptomatic pulmonary embolism (PE) at low-risk for short-term complications. PATIENTS AND METHODS:This study included a total of 154 consecutive patients diagnosed with acute symptomatic PE in a tertiary university ...

journal_title：Medicina clinica

authors： Quezada CA,Zamarro C,Gómez V,Guerassimova I,Nieto R,Barbero E,Chiluiza D,Barrios D,Morillo R,Jiménez D

更新日期：2018-08-22 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Pulmonary arterial hypertension associated with systemic lupus erythematosus (PAH-SLE) is a rare disease with a low incidence rate. In this study, PAH related genes and genetic modifiers were characterised molecularly in patients with PAH-SLE. PATIENTS AND METHODS:Three patients diagnosed with...

journal_title：Medicina clinica

authors： Pousada G,Lago-Docampo M,Baloira A,Valverde D

更新日期：2018-08-10 00:00:00

abstract：:The term cryptogenic stroke refers to a stroke for which there is no specific attributable cause after a comprehensive evaluation. However, there are differences between the diagnostic criteria of etiological classifications used in clinical practice. An improvement in diagnostic tools such advances in monitoring for ...

journal_title：Medicina clinica

authors： Gutiérrez-Zúñiga R,Fuentes B,Díez-Tejedor E

更新日期：2018-08-10 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To evaluate the adherence to the recommendations in clinical practice performed by the Therapeutic Positioning Report (TPR) of the Spanish Agency of Medicines and Sanitary Products about the treatment with oral anticoagulants in patients aged≥75 years old with nonvalvular atrial fibrillation (N...

journal_title：Medicina clinica

authors： Suárez Fernández C,Mostaza JM,Castilla Guerra L,Cantero Hinojosa J,Suriñach JM,Acosta de Bilbao F,Tamarit JJ,Diaz Diaz JL,Hernandez JL,Cazorla D,Ràfols C,en nombre de los Investigadores del Estudio ESPARTA.

更新日期：2018-07-13 00:00:00

abstract：INTRODUCTION AND OBJECTIVE:The albumin-cytologic dissociation in cerebrospinal fluid (CSF) supports the diagnosis of Guillain-Barre syndrome (GBS) but does not support the prognosis, so the aim of this study is to determine the usefulness of protein numbers in the CSF to predict progression in paediatric patients. PAT...

journal_title：Medicina clinica

authors： Vidrio-Becerra ME,Valle-Leal J,Loaiza-Sarabia ME,Alvarez-Bastidas L,Lachica-Valle JI,López-Morales CM

更新日期：2018-05-11 00:00:00

abstract：:Practicing sports at a professional level requires the body to be in good health. The fact of carrying out a continuous and high intensity physical activity in the presence of pathological conditions and/or a maladaptation of the body can be detrimental to the athletes' health and, therefore, to their performance. Man...

journal_title：Medicina clinica

authors： Pruna R,Lizarraga A,Domínguez D

更新日期：2018-04-13 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Direct oral anticoagulants (DOACs) require dose adjustment according to estimated clearance creatinine (eClCr) using the Cockcroft-Gault (CG) equation. There are discrepancies with the equations that estimate glomerular filtration rate (eGFR). We analyse how the use of the CKD-EPI and MDRD-4 ID...

journal_title：Medicina clinica

authors： Pérez Cabeza AI,Chinchurreta Capote PA,González Correa JA,Ruiz Mateas F,Rosas Cervantes G,Rivas Ruiz F,Valle Alberca A,Bravo Marqués R

更新日期：2018-02-09 00:00:00

abstract：INTRODUCTION AND AIMS:A high quality colonoscopy is key in preventing colorectal cancer, but the risk of colorectal cancer (CRC) exists. The aims of the study were to investigate the incidence, characteristics and predictive factors of post-colonoscopy colorectal cancer (PCCRC). MATERIAL AND METHOD:A retrospective and...

journal_title：Medicina clinica

authors： Muñoz García-Borruel M,Hervás Molina AJ,Rodríguez Perálvarez ML,Moreno Rincón E,Pérez Medrano I,Serrano Ruiz FJ,Casáis Juanena LL,Pleguezuelo Navarro M,Naranjo Rodríguez A,Villar Pastor C

更新日期：2018-01-12 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) consists of an excessive depositing of fat in the liver, which can end up by causing inflammation, fibrosis and also cirrhosis with the corresponding complications including liver cancer. NAFLD has become the most common liver disease worldwide. The incidence has increased in ...

journal_title：Medicina clinica

authors： Augustin S,Graupera I,Caballeria J,en nombre del grupo de trabajo sobre «Hígado graso no alcohólico» de la Societat Catalana de Digestologia.

更新日期：2017-12-20 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Arterial stiffness (AS) is a well-recognized target organ lesion. This study aims to determine: 1) the frequency of AS in community pharmacies; 2) if stiffened subjects identified by brachial oscillometry have more CV risk factors than normal subjects, and 3) the dependence of stiffness on usin...

journal_title：Medicina clinica

authors： Rodilla Sala E,Adell Alegre M,Giner Galvañ V,Perseguer Torregrosa Z,Pascual Izuel JM,Climent Catalá MT,en nombre del Grupo de estudio RIVALFAR.

更新日期：2017-12-07 00:00:00

abstract：INTRODUCTION AND OBJECTIVES:Dilatation of the ascending aorta associated with bicuspid aortic valve is a major cause of morbidity and mortality in adults. The main objective was to recognize the aortic involvement in children, its characteristics and risk factors. METHODS:Aortic measures of all pediatric patients with...

journal_title：Medicina clinica

authors： Sabaté-Rotés A,Sabidó Sanchez L,Gran Ipiña F,Albert Brotons D,Abella RF,Rosés Noguer F

更新日期：2017-11-09 00:00:00

abstract：INTRODUCTION AND OBJECTIVE:To achieve control of rheumatoid arthritis (RA) it is necessary to be able to evaluate its activity. The American College of Rheumatology (ACR) recommends for this purpose indexes of activity that can be performed by the patient (PAS-II and RAPID-3) and IA including medical evaluation with la...

journal_title：Medicina clinica

authors： Horta-Baas G,Pérez Bolde-Hernández A,Hernández-Cabrera MF,Vergara-Sánchez I,Romero-Figueroa MDS

更新日期：2017-10-11 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Functional assessment is especially relevant in patients with cognitive impairment (CI). The Disability Assessment for Dementia (DAD) scale assesses functional ability and its use is becoming increasingly popular. This study aims to perform the translation and cultural adaptation of the DAD sca...

journal_title：Medicina clinica

authors： Sánchez-Pérez A,López-Roig S,Pampliega Pérez A,Peral Gómez P,Pastor MÁ,Hurtado-Pomares M

更新日期：2017-09-20 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Diffuse idiopathic skeletal hyperostosis (DISH) and abdominal aortic calcification (AAC) are related to an increased cardiovascular risk. The aim of this study was to analyse a possible relationship between both entities and also the association between metabolic disorders and DISH. PATIENTS A...

journal_title：Medicina clinica

authors： Pariente-Rodrigo E,Sgaramella GA,Olmos-Martínez JM,Pini-Valdivieso SF,Landeras-Alvaro R,Hernández-Hernández JL

更新日期：2017-09-08 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Alcohol and its metabolites play an important role in carcinogenesis. This effect could be modulated by polymorphisms in genes encoding enzymes involved in the metabolism of alcohol and folate. Therefore, we analyzed the effect of alcohol consumption and ADH1B Arg48His, ADH1B Arg370Cys, ADH1C I...

journal_title：Medicina clinica

authors： Álvarez-Avellón SM,Fernández-Somoano A,Navarrete-Muñoz EM,Vioque J,Tardón A

更新日期：2017-06-21 00:00:00

abstract：:Patients with inflammatory bowel disease constitute a population with a special predisposition to develop bacterial, viral and fungal infections. Iatrogenic immunosuppression, frequent contact with healthcare facilities and surgical interventions are some of the risk factors that explain why these infections are one o...

journal_title：Medicina clinica

authors： Rodríguez de Santiago E,Albillos Martínez A,López-Sanromán A

更新日期：2017-05-10 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Strategies to improve the efficiency of bronchoalveolar lavage (BAL) are needed. We conducted a study to establish the diagnostic value of BAL in patients with hematological malignancies and pulmonary infiltrates. PATIENTS AND METHODS:The correlation of cytologic and flow cytometric study of ...

journal_title：Medicina clinica

authors： Ferrà C,Xicoy B,Castillo N,Morgades M,Juncà J,Andreo F,Millá F,Feliu E,Ribera JM

更新日期：2017-04-07 00:00:00