听力与言语-语言病理学

行为科学

医学伦理学

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  • Determining Factors in the Therapeutic Success of Checkpoint Immunotherapies against PD-L1 in Breast Cancer: A Focus on Epithelial-Mesenchymal Transition Activation.

    abstract::Breast cancer is the most common neoplasm diagnosed in women around the world. Checkpoint inhibitors, targeting the programmed death receptor-1 or ligand-1 (PD-1/PD-L1) axis, have dramatically changed the outcome of cancer treatment. These therapies have been recently considered as alternatives for treatment of breast...

    journal_title:Journal of immunology research

    pub_type: 杂志文章,评审

    doi:10.1155/2021/6668573

    authors: Segovia-Mendoza M,Romero-Garcia S,Lemini C,Prado-Garcia H

    更新日期:2021-01-07 00:00:00

  • DHX37 Impacts Prognosis of Hepatocellular Carcinoma and Lung Adenocarcinoma through Immune Infiltration.

    abstract:Background:RNA helicases have various essential functions in basically all aspects of RNA metabolism, not only unwinding RNA but also disturbing the interaction of RNA with proteins. Recently, RNA helicases have been considered potential targets in cancers. So far, there has been no detailed investigation of the biolog...

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2020/8835393

    authors: Xu Y,Jiang Q,Liu H,Xiao X,Yang D,Saw PE,Luo B

    更新日期:2020-12-30 00:00:00

  • Gastrospheres as a Model of Gastric Cancer Stem Cells Skew Th17/Treg Balance toward Antitumor Th17 Cells.

    abstract:Background:Gastrosphere, an enriched cellular population with stem-like properties believed to be responsible for an escape from immune-mediated destruction. Th17 and Treg cells play a major role in gastric cancer; however, their interaction with gastrospheres remained elusive. Method:Peripheral blood mononuclear cell...

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2020/6261814

    authors: Rezalotfi A,Solgi G,Ebrahimi M

    更新日期:2020-12-23 00:00:00

  • Circulating Monocytic Myeloid-Derived Suppressor Cells Are Elevated and Associated with Poor Prognosis in Acute Myeloid Leukemia.

    abstract:Background:Monocytic myeloid-derived suppressor cells (M-MDSCs) characterized with the phenotype of CD14+HLA-DRlow/- have attracted a lot of attention in the field of human tumor immunology. However, little is known about the roles of M-MDSCs in acute myeloid leukemia (AML) as opposed to their multiple roles in solid t...

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2020/7363084

    authors: Wang H,Tao Q,Wang Z,Zhang Q,Xiao H,Zhou M,Dong Y,Zhai Z

    更新日期:2020-12-21 00:00:00

  • Tissue-Resident Type 2 Innate Lymphoid Cells Arrest Alveolarization in Bronchopulmonary Dysplasia.

    abstract::Bronchopulmonary dysplasia (BPD) is a severe complication of the respiratory system associated with preterm birth. Type 2 innate lymphoid cells (ILC2s) play a major role in tissue homeostasis, inflammation, and wound healing. However, the role in BPD remains unclear. The present study showed that ILC2s, interleukin-4 ...

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2020/8050186

    authors: Mi L,Zhu S,Cai J,Xu S,Xue Z,Lu H

    更新日期:2020-10-31 00:00:00

  • FOXP3 in Melanoma with Regression: Between Tumoral Expression and Regulatory T Cell Upregulation.

    abstract::Cutaneous melanoma is a significant immunogenic tumoral model, the most frequently described immune phenomenon being tumor regression, as a result of the interaction of tumoral antigens and stromal microenvironment. We present a retrospective cohort study including 52 cases of melanoma with regression. There were eval...

    journal_title:Journal of immunology research

    pub_type: 杂志文章,评审

    doi:10.1155/2020/5416843

    authors: Cioplea M,Nichita L,Georgescu D,Sticlaru L,Cioroianu A,Nedelcu R,Turcu G,Rauta A,Mogodici C,Zurac S,Popp C

    更新日期:2020-10-23 00:00:00

  • The Effectiveness of Rapamycin Combined with Eltrombopag in Murine Models of Immune-Mediated Bone Marrow Failure.

    abstract::Severe aplastic anemia (SAA) is a rare disease characterized by severe pancytopenia and bone marrow failure. Most patients with AA respond to immunosuppressive therapy (IST), usually as antithymocyte globulin (ATG) and cyclosporine (CsA), but some relapse on CsA withdrawal or require long-term administration of CsA to...

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2020/1798795

    authors: Ding S,Liang X,Zhang T,Fu R

    更新日期:2020-10-17 00:00:00

  • Elucidating the Pivotal Immunomodulatory and Anti-Inflammatory Potentials of Chloroquine and Hydroxychloroquine.

    abstract::Chloroquine (CQ) and hydroxychloroquine (HCQ) are derivatives of 4-aminoquinoline compounds with over 60 years of safe clinical usage. CQ and HCQ are able to inhibit the production of cytokines such as interleukin- (IL-) 1, IL-2, IL-6, IL-17, and IL-22. Also, CQ and HCQ inhibit the production of interferon- (IFN-) α a...

    journal_title:Journal of immunology research

    pub_type: 杂志文章,评审

    doi:10.1155/2020/4582612

    authors: Richard SA,Kampo S,Hechavarria ME,Sackey M,Buunaaim ADB,Kuugbee ED,Anabah TW

    更新日期:2020-09-25 00:00:00

  • Thymic Stromal Lymphopoietin Is Implicated in the Pathogenesis of Bullous Pemphigoid by Dendritic Cells.

    abstract:Objectives:Both thymic stromal lymphopoietin (TSLP) and dendritic cells (DCs) are involved in many autoimmune diseases, but the potential roles of TSLP and DCs in bullous pemphigoid (BP) have not been clarified. We sought to explore the contributions of TSLP and DCs in patients with BP. Methods:TSLP levels in sera and...

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2020/4594630

    authors: Li SZ,Jin XX,Ge XL,Zuo YG,Jin HZ

    更新日期:2020-09-24 00:00:00

  • sB7H3 in Children with Acute Appendicitis: Its Diagnostic Value and Association with Histological Findings.

    abstract:Background:Several efforts have been made to find out a valuable marker to assist the diagnosis and differentiation of gangrenous/perforated appendicitis. We aimed to determine the diagnostic capacity of soluble B7H3 (sB7H3) in acute appendicitis (AA) and its accuracy as a predictor of the severity of appendicitis. Me...

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2020/2670527

    authors: Du X,Chen Y,Zhu J,Bai Z,Hua J,Li Y,Lv H,Zhang G

    更新日期:2020-09-01 00:00:00

  • Protective Effects of Thalidomide on High-Glucose-Induced Podocyte Injury through In Vitro Modulation of Macrophage M1/M2 Differentiation.

    abstract::Objective. It has been shown that podocyte injury represents an important pathological basis that contributes to proteinuria and eventually leads to kidney failure. High glucose (HG) activates macrophage polarization, further exacerbating HG-induced podocyte injury. Our previous study on diabetic nephropathy rats indi...

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2020/8263598

    authors: Liao H,Li Y,Zhang X,Zhao X,Zheng D,Shen D,Li R

    更新日期:2020-08-27 00:00:00

  • MPC1 Deficiency Promotes CRC Liver Metastasis via Facilitating Nuclear Translocation of β-Catenin.

    abstract::Accumulating evidence has pointed out that metastasis is the leading cause of death in several malignant tumor, including CRC. During CRC, metastatic capacity is closely correlated with reprogrammed energy metabolism. Mitochondrial Pyruvate Carrier 1 (MPC1), as the carrier of transporting pyruvate into mitochondria, l...

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2020/8340329

    authors: Tian GA,Xu CJ,Zhou KX,Zhang ZG,Gu JR,Zhang XL,Wang YH

    更新日期:2020-08-19 00:00:00

  • ChIP-seq Profiling Identifies Histone Deacetylase 2 Targeting Genes Involved in Immune and Inflammatory Regulation Induced by Calcitonin Gene-Related Peptide in Microglial Cells.

    abstract::Calcitonin gene-related peptide (CGRP) is a mediator of microglial activation at the transcriptional level. The involvement of the epigenetic mechanism in this process is largely undefined. Histone deacetylase (HDAC)1/2 are considered important epigenetic regulators of gene expression in activated microglia. In this s...

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2020/4384696

    authors: Guo X,Chen D,An S,Wang Z

    更新日期:2020-08-04 00:00:00

  • Regulating the Polarization of Macrophages: A Promising Approach to Vascular Dermatosis.

    abstract::Macrophages, a kind of innate immune cells, derive from monocytes in circulation and play a crucial role in the innate and adaptive immunity. Under the stimulation of the signals from local microenvironment, macrophages generally tend to differentiate into two main functional phenotypes depending on their high plastic...

    journal_title:Journal of immunology research

    pub_type: 杂志文章,评审

    doi:10.1155/2020/8148272

    authors: Peng H,Xian D,Liu J,Pan S,Tang R,Zhong J

    更新日期:2020-07-28 00:00:00

  • Association between Interleukin-10 Gene Polymorphisms and Behcet's Disease Susceptibility: Evidence from a Meta-Analysis.

    abstract::Epidemiological studies have demonstrated that interleukin-10 (IL-10) polymorphisms may be associated with the development of Behcet's disease (BD). However, the published results were inconsistent. Therefore, this meta-analysis was conducted to derive a more precise relationship between IL-10 polymorphisms and BD sus...

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2020/9382609

    authors: Li XF,Huang ZZ,Hu YY,Niu YM,Cai JW

    更新日期:2020-06-19 00:00:00

  • Use of Chlorogenic Acid against Diabetes Mellitus and Its Complications.

    abstract::Chlorogenic acid (CA) is a phenolic compound commonly found in human plant-based diets. CA is the main component of many traditional Chinese medicine preparations, and in recent years, it has been found to have hypoglycemic, hypolipidemic, anti-inflammatory, antioxidant, and other pharmacological properties. Specifica...

    journal_title:Journal of immunology research

    pub_type: 杂志文章,评审

    doi:10.1155/2020/9680508

    authors: Yan Y,Zhou X,Guo K,Zhou F,Yang H

    更新日期:2020-05-28 00:00:00

  • The Impact of Psoriasis and Metabolic Syndrome on the Systemic Inflammation and Oxidative Damage to Nucleic Acids.

    abstract:Background:Psoriasis is a chronic systemic inflammatory disease associated with a wide range of comorbidities, including metabolic syndrome (MetS). Serum calprotectin, ANGPTL8, and oxidative damage to nucleic acids might be associated with both diseases. The presented study describes the influence of psoriasis and MetS...

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2020/7352637

    authors: Holmannova D,Borska L,Andrys C,Borsky P,Kremlacek J,Hamakova K,Rehacek V,Malkova A,Svadlakova T,Palicka V,Krejsek J,Fiala Z

    更新日期:2020-05-20 00:00:00

  • Circulating miRNAs as Biomarkers for Prostate Cancer Diagnosis in Subjects with Benign Prostatic Hyperplasia.

    abstract::Body fluids often contain freely circulating nucleic acids, many of which can be exploited as noninvasive tools for the diagnosis of cancer as well as for clinical prognostication. Identifying microRNAs (miRNAs) in subjects' blood with various malignancies means that they can serve as novel biomarkers for prostate can...

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2020/5873056

    authors: Jin W,Fei X,Wang X,Chen F,Song Y

    更新日期:2020-05-08 00:00:00

  • The Interplay of Renin-Angiotensin System and Toll-Like Receptor 4 in the Inflammation of Diabetic Nephropathy.

    abstract::Diabetic nephropathy (DN) is one of the most serious chronic kidney diseases and the major cause of end-stage renal failure worldwide. The underlying mechanisms of DN are complex and required to be further investigated. Both innate immunity and renin-angiotensin system (RAS) play critical roles in the pathogenesis of ...

    journal_title:Journal of immunology research

    pub_type: 杂志文章,评审

    doi:10.1155/2020/6193407

    authors: Feng Q,Liu D,Lu Y,Liu Z

    更新日期:2020-04-30 00:00:00

  • Elevated Expression of C-Type Lectin Domain Family 5-Member A (CLEC5A) and Its Relation to Inflammatory Parameters and Disease Course in Adult-Onset Still's Disease.

    abstract::C-type lectin domain family 5-member A (CLEC5A) associates with adaptor DAP12 (DNAX activation protein 12) to form receptor complexes involved in inflammatory responses. We postulated a potential role of CLEC5A in the pathogenesis of adult-onset Still's disease (AOSD) and aimed to investigate CLEC5A expression and its...

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2020/9473497

    authors: Chen PK,Hsieh SL,Lan JL,Lin CC,Chang SH,Chen DY

    更新日期:2020-04-23 00:00:00

  • Expression and Significance of Immune Checkpoints in Clear Cell Carcinoma of the Uterine Cervix.

    abstract::The purpose of this study was to investigate the expression levels of the immune checkpoint proteins, programmed cell death-ligand 1 (PD-L1), B7-H3, B7-H4, and V-domain Ig suppressor of T cell activation (VISTA), as well as the significance thereof, in clear cell carcinoma (CCC) of the cervix (a rare histological subt...

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2020/1283632

    authors: Zong L,Zhang Q,Zhou Y,Kong Y,Yu S,Chen J,Zhang Y,Xiang Y

    更新日期:2020-04-03 00:00:00

  • Peripheral B Cell Subsets in Autoimmune Diseases: Clinical Implications and Effects of B Cell-Targeted Therapies.

    abstract::Antibody-secreting cells (ASCs) play a fundamental role in humoral immunity. The aberrant function of ASCs is related to a number of disease states, including autoimmune diseases and cancer. Recent insights into activated B cell subsets, including naïve B cell to ASC stages and their resultant cellular disturbances, s...

    journal_title:Journal of immunology research

    pub_type: 杂志文章,评审

    doi:10.1155/2020/9518137

    authors: Jin W,Luo Z,Yang H

    更新日期:2020-03-23 00:00:00

  • Genetic Background of Hypertension in Connective Tissue Diseases.

    abstract::Peroxisome proliferator-activated receptors (PPAR gamma-2) and beta-3-adrenergic receptors (ADRB3) are involved in the risk of hypertension. But their exact role in blood pressure modulation in patients with connective tissue diseases (CTD) is still not well defined. In this study, 104 patients with CTD and 103 gender...

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2020/7509608

    authors: Grygiel-Górniak B,Ziółkowska-Suchanek I,Kaczmarek E,Puszczewicz M,Rozwadowska N

    更新日期:2020-02-03 00:00:00

  • The First Report of Immunoglobulin G, M, and A Concentrations in Serum of European Bison and Their Changes with Age.

    abstract::The age-specific reference values for immunoglobulin (Ig) serum concentrations in European bison (Bison bonasus) are lacking. Identification of immune alterations that accompany normal physiological aging will help assist in development of better monitoring health programs. In the present study, the age-associated cha...

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2020/2614317

    authors: Pomorska-Mól M,Krzysiak MK,Larska M,Włodarek J

    更新日期:2020-01-23 00:00:00

  • A Multiple Antigen Peptide Vaccine Containing CD4+ T Cell Epitopes Enhances Humoral Immunity against Trichinella spiralis Infection in Mice.

    abstract::Multiepitope peptide vaccine has some advantages over traditional recombinant protein vaccine due to its easy and fast production and possible inclusion of multiple protective epitopes of pathogens. However, it is usually poorly immunogenic and needs to conjugate to a large carrier protein. Peptides conjugated to a ce...

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2020/2074803

    authors: Gu Y,Sun X,Huang J,Zhan B,Zhu X

    更新日期:2020-01-08 00:00:00

  • Preliminary Evaluation of the Safety and Immunogenicity of an Antimalarial Vaccine Candidate Modified Peptide (IMPIPS) Mixture in a Murine Model.

    abstract::Malaria continues being a high-impact disease regarding public health worldwide; the WHO report for malaria in 2018 estimated that ~219 million cases occurred in 2017, mostly caused by the parasite Plasmodium falciparum. The disease cost the lives of more than 400,000 people, mainly in Africa. In spite of great effort...

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2019/3832513

    authors: Lambraño J,Curtidor H,Avendaño C,Díaz-Arévalo D,Roa L,Vanegas M,Patarroyo ME,Patarroyo MA

    更新日期:2019-12-30 00:00:00

  • Amiselimod (MT-1303), a Novel Sphingosine 1-Phosphate Receptor-1 Modulator, Potently Inhibits the Progression of Lupus Nephritis in Two Murine SLE Models.

    abstract::Amiselimod (MT-1303) is a novel and selective sphingosine 1-phosphate receptor-1 (S1P1) modulator with a more favorable cardiac safety profile than other S1P1 receptor modulators. In this study, we evaluated the effects of MT-1303 on the progression of lupus nephritis in two well-known murine systemic lupus erythemato...

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2019/5821589

    authors: Sugahara K,Maeda Y,Shimano K,Murase M,Mochiduki S,Takemoto K,Kakimoto T,Utsumi H,Oshita K,Kataoka H

    更新日期:2019-12-23 00:00:00

  • Analysis of Toll-Like Receptors in Human Milk: Detection of Membrane-Bound and Soluble Forms.

    abstract::The bioactive and anti-inflammatory role of human milk components has been recognized; active milk components include soluble forms of Toll-like receptors (TLRs). Preterm babies are more susceptible to infections and may succumb to necrotizing enterocolitis (NEC), a gastrointestinal disease which is exacerbated by an ...

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2019/4078671

    authors: Cattaneo C,Caramaschi A,Uga E,Braghin M,Cosi G,Peila C,Strozzi MC,Sabatini M,Gazzolo D,Manfredi M,Cavaletto M

    更新日期:2019-12-04 00:00:00

  • A Pilot Study of Echinocandin Combination with Trimethoprim/Sulfamethoxazole and Clindamycin for the Treatment of AIDS Patients with Pneumocystis Pneumonia.

    abstract:Background and Objectives:Pneumocystis pneumonia (PCP) is a common opportunistic infection in acquired immune deficiency syndrome (AIDS) patients that continues to result in a high mortality rate. To develop a better treatment strategy and improve PCP prognosis, a cohort study was conducted to evaluate the therapeutic ...

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2019/8105075

    authors: Wang M,Lang G,Chen Y,Hu C,Guo Y,Tao R,Dong X,Zhu B

    更新日期:2019-12-01 00:00:00

  • The Intracellular Growth of M. tuberculosis Is More Associated with High Glucose Levels Than with Impaired Responses of Monocytes from T2D Patients.

    abstract::Diabetes mellitus, a metabolic disease characterized by hyperglycemia and poor glucose control, is a risk factor for Mycobacterium tuberculosis (M. tuberculosis) infection and the development of active tuberculosis. To evaluate whether M. tuberculosis infection susceptibility is associated with an intrinsic factor in ...

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2019/1462098

    authors: Torres M,Herrera MT,Fabián-San-Miguel G,Gonzalez Y

    更新日期:2019-11-14 00:00:00

  • IL-6 Negatively Regulates IL-22Rα Expression on Epidermal Keratinocytes: Implications for Irritant Contact Dermatitis.

    abstract::Irritant Contact Dermatitis (ICD) is characterized by epidermal hyperplasia and inflammatory cytokine release. IL-6 has been shown to be involved in the pathogenesis of ICD; however, the involvement of the IL-22/IL-22Rα axis and its relation to IL-6 in the inflammatory response following irritant exposure are unknown....

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2019/6276254

    authors: Frempah B,Luckett-Chastain LR,Gallucci RM

    更新日期:2019-10-29 00:00:00

  • Cytokine Profile in Early Infection by Leptospira interrogans in A/J Mice.

    abstract::Leptospirosis is considered a neglected disease with an estimated more than one million cases every year. Since rodents are at the same time the main reservoir and generally asymptomatic to Leptospira infection, understanding why some animal species are resistant and others are susceptible to this infection would shed...

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2019/1892508

    authors: Bavia L,de Castro ÍA,Amano MT,da Silva AMG,Vasconcellos SA,Isaac L

    更新日期:2019-10-07 00:00:00

  • DKK2 Impairs Tumor Immunity Infiltration and Correlates with Poor Prognosis in Pancreatic Ductal Adenocarcinoma.

    abstract::Pancreatic ductal adenocarcinoma (PDAC) remains one of the most devastating cancer types despite the improvement of modern medicine. In our present study, we found that dickkopf-related protein 2 (DKK2) shares a higher expression in PDAC compared with adjacent pancreas tissue in tissue microarray. In addition, an elev...

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2019/8656282

    authors: Yang J,Jiang Y,He R,Liu W,Yang M,Tao L,Fu X,Shen Y,Li J,Liu D,Huo Y,Zhang J,Hua R,Zhang Z,Sun Y

    更新日期:2019-09-08 00:00:00

  • Human Platelet Lysate Media Supplement Supports Lentiviral Transduction and Expansion of Human T Lymphocytes While Maintaining Memory Phenotype.

    abstract::Immune cell therapy has emerged as a promising approach to treat malignancies that were up until recently only treated on a palliative basis. Chimeric antigen receptor- (CAR-) modified T lymphocytes (T cells) in particular have proven to be very effective for certain hematological malignancies. The production of CAR T...

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2019/3616120

    authors: Canestrari E,Steidinger HR,McSwain B,Charlebois SJ,Dann CT

    更新日期:2019-09-04 00:00:00

  • Immunomodulation of CXCL10 Secretion by Hepatitis C Virus: Could CXCL10 Be a Prognostic Marker of Chronic Hepatitis C?

    abstract::Chemokine (C-X-C motif) ligand (CXCL)10 and other CXCR3 chemokines are involved in the pathogenesis of acute and "chronic hepatitis C virus (HCV) infection" (CHC). Here, we review the scientific literature about HCV and CXCL10. The combination of circulating CXCL10 and single nucleotide polymorphisms (SNPs) in IL-28B ...

    journal_title:Journal of immunology research

    pub_type: 杂志文章,评审

    doi:10.1155/2019/5878960

    authors: Ferrari SM,Fallahi P,Ruffilli I,Elia G,Ragusa F,Paparo SR,Patrizio A,Mazzi V,Colaci M,Giuggioli D,Ferri C,Antonelli A

    更新日期:2019-08-08 00:00:00

  • Rapid and Efficient Purification of Functional Collectin-12 and Its Opsonic Activity against Fungal Pathogens.

    abstract::Collectin-12 (collectin placenta 1, CL-P1, or CL-12) is a newly identified pattern recognition molecule of the innate immune system. Recent evidences show that CL-12 plays important roles not only in innate immune protection against certain clinically important pathogens but also in scavenging of host molecules, leuko...

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2019/9164202

    authors: Zhang J,Li A,Yang CQ,Garred P,Ma YJ

    更新日期:2019-07-29 00:00:00

  • IL-7 is a Key Driver Cytokine in Spondyloarthritis?

    abstract::The rationale for a type 17 signature in the pathogenesis of spondyloarthritis (SpA) has been increasing and being ratified in studies recently. IL-7 is a cytokine whose ability to stimulate IL-17 production in both innate and adaptive immunity cells has made it a promising target not only for a better understanding o...

    journal_title:Journal of immunology research

    pub_type: 杂志文章,评审

    doi:10.1155/2019/7453236

    authors: Gonçalves RSG,Duarte ALBP

    更新日期:2019-05-29 00:00:00

  • TIM-3 and TIM-1 Could Regulate Decidual γδTCR Bright T Cells during Murine Pregnancy.

    abstract::Pregnancy is an immunological enigma where paternal antigens are present at the fetomaternal interface. What regulates the local immunotolerance, which is necessary to prevent rejection of the conceptus, is still under strong investigation. Gamma/delta T cells are believed to play a role in the local regulation of thi...

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2019/3836942

    authors: Nörenberg J,Meggyes M,Jakso P,Miko E,Barakonyi A

    更新日期:2019-05-20 00:00:00

  • Comparison of Inhibitory Effects of Safflower Decoction and Safflower Injection on Protein and mRNA Expressions of iNOS and IL-1β in LPS-Activated RAW264.7 Cells.

    abstract:Objective:Safflower has antioxidant and anti-inflammatory activities. The two forms of preparations for safflower which are widely used in China are injection and decoction. The first step of the process for preparing an injection involves extracting safflower with water, which actually yields a decoction. This study i...

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2019/1018274

    authors: Liao H,Li Y,Zhai X,Zheng B,Banbury L,Zhao X,Li R

    更新日期:2019-05-06 00:00:00

  • Assessment of Salivary Levels of RANKL and OPG in Aggressive versus Chronic Periodontitis.

    abstract::RANKL (receptor activator of nuclear factor kappa-β ligand) and OPG (osteoprotegerin) are two proteins involved in bone remodelling. During the active phase of periodontal disease, an imbalance between the ratios of the two elements can be noticed. While the expression of RANKL is elevated compared with that of OPG, t...

    journal_title:Journal of immunology research

    pub_type: 杂志文章

    doi:10.1155/2019/6195258

    authors: Teodorescu AC,Martu I,Teslaru S,Kappenberg-Nitescu DC,Goriuc A,Luchian I,Martu MA,Solomon SM,Mârțu S

    更新日期:2019-04-28 00:00:00

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