abstract：BACKGROUND:Intra-amniotic infection or inflammation (IAI) is common in early preterm birth and associated with significant neonatal lung morbidity due to fetal exposure to pro-inflammatory cytokines and infectious organisms. Amniotic fluid interleukin-8 (IL-8), a pro-inflammatory cytokine, was previously correlated wit...

journal_title：American journal of obstetrics and gynecology

authors： McCartney SA,Kapur R,Liggitt HD,Baldessari A,Coleman M,Orvis A,Ogle J,Katz R,Rajagopal L,Waldorf KMA

更新日期：2021-01-04 00:00:00

abstract：BACKGROUND:Noninvasive imaging autopsy alternatives for fetuses weighing <500 grams are limited. Microfocus computed tomography has been reported as a viable option in small case series with the potential to avoid an invasive autopsy. Implementation of postmortem microfocus computed tomography in a large cohort as part...

journal_title：American journal of obstetrics and gynecology

authors： Shelmerdine SC,Simcock IC,Hutchinson JC,Guy A,Ashworth MT,Sebire NJ,Arthurs OJ

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Pelvic organ prolapse is common, but the underlying etiologies are poorly understood, which limits our current prevention and treatment options. OBJECTIVE:Our primary objective was to compare the uterosacral ligament histologic features in women with and without prolapse using the novel pelvic organ prolaps...

journal_title：American journal of obstetrics and gynecology

authors： Orlicky DJ,Guess MK,Bales ES,Rascoff LG,Arruda JS,Hutchinson-Colas JA,Johnson J,Connell KA

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:One of the controversies in the management of twin gestations relates to mode of delivery, especially when the second twin is in a nonvertex presentation (Vertex/nonVertex pairs) and birth is imminent at extremely low gestation. OBJECTIVE:We hypothesized that, for Vertex/nonVertex twins born before 28 weeks...

journal_title：American journal of obstetrics and gynecology

authors： Hiersch L,Shah PS,Khurshid F,Masse E,Murphy K,McDonald SD,Carson G,Barrett J,Melamed N,Canadian Neonatal Network Investigators and the Canadian Preterm Birth Network Investigators.

更新日期：2020-12-09 00:00:00

abstract：:The rates of maternal morbidity and mortality in the United States demand a comprehensive approach to assessing pregnancy-related risks. Numerous medical and nonmedical factors contribute to maternal morbidity and mortality. Reducing the number of women who experience pregnancy morbidity requires identifying which wom...

journal_title：American journal of obstetrics and gynecology

authors： Society for Maternal-Fetal Medicine (SMFM).,Lappen JR,Pettker CM,Louis JM

更新日期：2020-12-09 00:00:00

abstract：:The placenta is a highly metabolically active organ fulfilling the bioenergetic and biosynthetic needs to support its own rapid growth and that of the fetus. Placental metabolic dysfunction is a common occurrence in preeclampsia although its causal relationship to the pathophysiology is unclear. At the outset, this ma...

journal_title：American journal of obstetrics and gynecology

authors： Aye ILMH,Aiken CE,Charnock-Jones DS,Smith GCS

更新日期：2020-11-13 00:00:00

abstract：:Optimal management of HIV-positive pregnant individuals involves many specific interventions made by many healthcare professionals at specific time-points before, during, and after pregnancy. Errors of omission are likely unless those professionals use a cognitive aid such as a checklist as a reminder of critical step...

journal_title：American journal of obstetrics and gynecology

authors： Patient Safety and Quality Committee, Society for Maternal-Fetal Medicine. Electronic address: smfm@smfm.org.,Gibson KS,Toner LE

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:First-trimester ultrasound scans were introduced to China for nearly 20 years. The ability of first-trimester ultrasound screening to detect different malformations was variable. A recent systematic review concluded that the use of a standardized anatomic protocol was the most crucial factor to improve the s...

journal_title：American journal of obstetrics and gynecology

authors： Liao Y,Wen H,Ouyang S,Yuan Y,Bi J,Guan Y,Fu Q,Yang X,Guo W,Huang Y,Zeng Q,Qin Y,Xiang H,Li S

更新日期：2020-10-27 00:00:00

abstract：BACKGROUND:The ideal measure of success after surgery for pelvic organ prolapse has long been debated. Historically, strict definitions based on anatomic perfection have dominated the literature. However, the importance of patient-centered perception of outcomes is equally or more important when comparing the success o...

journal_title：American journal of obstetrics and gynecology

authors： Jelovsek JE,Gantz MG,Lukacz E,Sridhar A,Zyczynski H,Harvie HS,Dunivan G,Schaffer J,Sung V,Varner RE,Mazloomdoost D,Barber MD,Eunice Kennedy Shriver National Institute of Child Health and Human Development Pelvic Floor Disorders N

更新日期：2020-10-08 00:00:00

abstract：BACKGROUND:Polycystic ovary syndrome is the most common endocrine disorder affecting women of reproductive age. A number of criteria have been developed for clinical diagnosis of polycystic ovary syndrome, with the Rotterdam criteria being the most inclusive. Evidence suggests that polycystic ovary syndrome is signific...

journal_title：American journal of obstetrics and gynecology

authors： Zhang Y,Ho K,Keaton JM,Hartzel DN,Day F,Justice AE,Josyula NS,Pendergrass SA,Actkins K,Davis LK,Velez Edwards DR,Holohan B,Ramirez A,Stanaway IB,Crosslin DR,Jarvik GP,Sleiman P,Hakonarson H,Williams MS,Lee MTM

更新日期：2020-10-01 00:00:00

abstract：:Preeclampsia is a major obstetrical complication with short- and long-term life-threatening consequences for both mother and child. Shallow cytotrophoblast invasion through the uterine decidua into the spiral arteries is implicated in the pathogenesis of preeclampsia, although the cause of deficient arterial invasion ...

journal_title：American journal of obstetrics and gynecology

authors： Garrido-Gómez T,Castillo-Marco N,Cordero T,Simón C

更新日期：2020-09-29 00:00:00

abstract：BACKGROUND:Transgender, nonbinary, and gender-expansive people who were assigned female or intersex at birth experience pregnancy and have abortions. Scarce data have been published on individual abortion experiences or preferences of this understudied population. OBJECTIVE:This study aimed to fill existing evidence g...

journal_title：American journal of obstetrics and gynecology

authors： Moseson H,Fix L,Ragosta S,Forsberg H,Hastings J,Stoeffler A,Lunn MR,Flentje A,Capriotti MR,Lubensky ME,Obedin-Maliver J

更新日期：2020-09-25 00:00:00

abstract：OBJECTIVE:After strong evidence and major organizations recommending salpingectomy over tubal ligation, we sought to perform a systematic review and meta-analysis comparing the intraoperative attributes and complication rates associated with these 2 procedures. DATA SOURCES:We searched PubMed, the Cochrane Library, Em...

journal_title：American journal of obstetrics and gynecology

authors： Mills K,Marchand G,Sainz K,Azadi A,Ware K,Vallejo J,Anderson S,King A,Osborn A,Ruther S,Brazil G,Cieminski K,Hopewell S,Rials L,Klipp A

更新日期：2020-09-14 00:00:00

abstract：BACKGROUND:A growing literature suggests that minority races, particularly Black women, have a lower probability of live birth and higher risk of perinatal complications after autologous assisted reproductive technology. However, questions still remain as to whether these racial disparities have arisen because of assoc...

journal_title：American journal of obstetrics and gynecology

authors： Liu Y,Hipp HS,Nagy ZP,Capelouto SM,Shapiro DB,Spencer JB,Gaskins AJ

更新日期：2020-09-12 00:00:00

abstract：BACKGROUND:Medical school graduates should be able to enter information from patient encounters and to write orders and prescriptions in the electronic health record. Studies have shown that, although students often can access electronic health records, some students may receive inadequate preparation for these skills....

journal_title：American journal of obstetrics and gynecology

authors： Hammoud MM,Foster LM,Cuddy MM,Swanson DB,Wallach PM

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:In some women placental function may not be adequate to meet fetal growth requirements in late pregnancy or the additional demands during labor, thus predisposing these infants to intrapartum fetal compromise and subsequent serious morbidity and mortality. The objective of this study was to det...

journal_title：American journal of obstetrics and gynecology

authors： Sherrell HC,Clifton VL,Kumar S

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Early spontaneous preterm delivery is often associated with microbial invasion of the amniotic cavity and/or intraamniotic inflammation. OBJECTIVE:The objective of the study was to develop and validate clinically feasible multivariable prediction models of spontaneous delivery within 7 days and microbial in...

journal_title：American journal of obstetrics and gynecology

authors： Cobo T,Aldecoa V,Figueras F,Herranz A,Ferrero S,Izquierdo M,Murillo C,Amoedo R,Rueda C,Bosch J,Martínez-Portilla RJ,Gratacós E,Palacio M

更新日期：2020-09-01 00:00:00

abstract：:Each year, nearly 4 million pregnant patients in the United States receive prenatal care-a crucial preventive service that improves pregnancy outcomes for mothers and their children. National guidelines currently recommend 12-14 in-person prenatal visits, a schedule that has remained unchanged since 1930. When scrutin...

journal_title：American journal of obstetrics and gynecology

authors： Peahl AF,Smith RD,Moniz MH

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:The process of childbirth is one of the most crucial events in the future health and development of the offspring. The vulnerability of parturients and fetuses during the delivery process led to the development of intrapartum monitoring methods and to the emergence of alternative methods of delivery. However...

journal_title：American journal of obstetrics and gynecology

authors： Guedalia J,Lipschuetz M,Novoselsky-Persky M,Cohen SM,Rottenstreich A,Levin G,Yagel S,Unger R,Sompolinsky Y

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Noninvasive monitoring of fetal development and the early detection of pregnancy-associated complications is challenging, largely because of the lack of information about the molecular spectrum during pregnancy. Recently, cell-free DNA in plasma was found to reflect the global nucleosome footprint and status...

journal_title：American journal of obstetrics and gynecology

authors： Han BW,Yang F,Guo ZW,Ouyang GJ,Liang ZK,Weng RT,Yang X,Huang LP,Wang K,Li FX,Huang J,Yang XX,Wu YS

更新日期：2020-08-29 00:00:00

abstract：BACKGROUND:Open spina bifida is a major congenital anomaly with an estimated incidence of <1 in 1000. The diagnosis of open spina bifida is usually made during the second trimester, but first-trimester detection rate of spina bifida is increasingly reported. Recently, the mean choroid plexus length to occipitofrontal d...

journal_title：American journal of obstetrics and gynecology

authors： Kalafat E,Ting L,Thilaganathan B,Papageorghiou AT,Khalil A

更新日期：2020-08-22 00:00:00

abstract：:Preeclampsia is defined as hypertension arising after 20 weeks of gestational age with proteinuria or other signs of end-organ damage and is an important cause of maternal and perinatal morbidity and mortality, particularly when of early onset. Although a significant amount of research has been dedicated in identifyin...

journal_title：American journal of obstetrics and gynecology

authors： Rolnik DL,Nicolaides KH,Poon LC

更新日期：2020-08-21 00:00:00

abstract：BACKGROUND:Uterine leiomyosarcoma is a rare and aggressive gynecologic malignancy originating in the myometrium of the uterine corpus that tends to recur even after complete surgical excision. Current therapeutic agents have only modest effects on uterine leiomyosarcoma. Although antibodies and antibody-drug conjugates...

journal_title：American journal of obstetrics and gynecology

authors： Nakae R,Matsuzaki S,Serada S,Matsuo K,Shiomi M,Sato K,Nagase Y,Matsuzaki S,Nakagawa S,Hiramatsu K,Okazawa A,Kimura T,Egawa-Takata T,Kobayashi E,Ueda Y,Yoshino K,Naka T,Kimura T

更新日期：2020-08-19 00:00:00

abstract：BACKGROUND:In 2017, the Dutch cervical cancer screening program had replaced the primary cytology-based screening with primary high-risk human papillomavirus-based screening, including the opportunity to participate through self-sampling. Evaluation and balancing benefit (detection of high-grade cervical intraepithelia...

journal_title：American journal of obstetrics and gynecology

authors： Loopik DL,Koenjer LM,Siebers AG,Melchers WJG,Bekkers RLM

更新日期：2020-08-13 00:00:00

abstract：BACKGROUND:The diagnostic criteria for preeclampsia have evolved from the traditional definition of de novo hypertension and proteinuria to a broader definition of hypertension with evidence of end-organ dysfunction. Although this change is endorsed by various societies such as the International Society for the Study o...

journal_title：American journal of obstetrics and gynecology

authors： Reddy M,Fenn S,Rolnik DL,Mol BW,da Silva Costa F,Wallace EM,Palmer KR

更新日期：2020-08-12 00:00:00

abstract：BACKGROUND:The American Heart Association's formal characterization of cardiovascular health combines several metrics in a health-oriented, rather than disease-oriented, framework. Although cardiovascular health assessment during pregnancy has been recommended, its significance for pregnancy outcomes is unknown. OBJEC...

journal_title：American journal of obstetrics and gynecology

authors： Perak AM,Lancki N,Kuang A,Labarthe DR,Allen NB,Shah SH,Lowe LP,Grobman WA,Scholtens DM,Lloyd-Jones DM,Lowe WL Jr,Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study Cooperative Research Group.

更新日期：2020-08-05 00:00:00

abstract：:Progesterone is essential for the maintenance of pregnancy. Several small trials have suggested that progesterone supplementation may reduce the risk of miscarriage in women with recurrent or threatened miscarriage. Cochrane Reviews summarized the evidence and found that the trials were small with substantial methodol...

journal_title：American journal of obstetrics and gynecology

authors： Coomarasamy A,Devall AJ,Brosens JJ,Quenby S,Stephenson MD,Sierra S,Christiansen OB,Small R,Brewin J,Roberts TE,Dhillon-Smith R,Harb H,Noordali H,Papadopoulou A,Eapen A,Prior M,Di Renzo GC,Hinshaw K,Mol BW,Lumsden MA

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Planned home births have leveled off in the United States in recent years after a significant rise starting in the mid-2000s. Planned home births in the United States are associated with increased patient-risk profiles. Multiple studies concluded that, compared with hospital births, absolute and relative ris...

journal_title：American journal of obstetrics and gynecology

authors： Grünebaum A,McCullough LB,Orosz B,Chervenak FA

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:A rapid increase in restrictive abortion legislation in the United States has sparked renewed interest in self-managed abortion as a response to clinic access barriers. Yet little is known about knowledge of, interest in, and experiences of self-managed medication abortion among patients who obtain abortion ...

journal_title：American journal of obstetrics and gynecology

authors： Aiken ARA,Broussard K,Johnson DM,Padron E,Starling JE,Scott JG

更新日期：2020-08-01 00:00:00

abstract：:Despite current recommendations against its use, activity restriction remains a common intervention used to prevent preterm birth in multiple clinical settings. Hypertensive disorders of pregnancy, preterm premature rupture of membranes, multiple gestations, vaginal bleeding, short cervical length, placenta previa, an...

journal_title：American journal of obstetrics and gynecology

authors： Society for Maternal-Fetal Medicine (SMFM). Electronic address: pubs@smfm.org.,Lauder J,Sciscione A,Biggio J,Osmundson S

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Venous thromboembolism events, including deep venous thrombosis and pulmonary embolism are the most common cause of preventable deaths in hospitalized patients in the United States. Although the risk of venous thromboembolism events in benign gynecologic surgery is generally low, the potential for venous thr...

journal_title：American journal of obstetrics and gynecology

authors： Chong W,Bui AH,Menhaji K

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVE:We performed a systematic review and meta-analysis to determine whether D-mannose reduces urinary tract infection recurrence (ie, cumulative incidence) in adult women with recurrent urinary tract infection compared with other prevention agents. Secondary outcomes included side effects and compliance with D-ma...

journal_title：American journal of obstetrics and gynecology

authors： Lenger SM,Bradley MS,Thomas DA,Bertolet MH,Lowder JL,Sutcliffe S

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Twin anemia polycythemia sequence is a chronic form of unbalanced fetofetal transfusion through minuscule placental anastomoses in monochorionic twins, leading to anemia in the donor and polycythemia in the recipient. Owing to the low incidence of twin anemia polycythemia sequence, data on diagnosis, managem...

journal_title：American journal of obstetrics and gynecology

authors： Tollenaar LSA,Slaghekke F,Lewi L,Colmant C,Lanna M,Weingertner AS,Ryan G,Arévalo S,Klaritsch P,Tavares de Sousa M,Khalil A,Papanna R,Gardener GJ,Bevilacqua E,Kostyukov KV,Bahtiyar MO,Kilby MD,Tiblad E,Oepkes D,Lopri

更新日期：2020-07-27 00:00:00

abstract：BACKGROUND:Periconceptional diet quality is commonly suboptimal and sociodemographic disparities in diet quality exist. However, it is unknown whether individual periconceptional diet quality is associated with obstetric outcomes. OBJECTIVE:Our objective was to assess differences in maternal and neonatal outcomes acco...

journal_title：American journal of obstetrics and gynecology

authors： Yee LM,Silver RM,Haas DM,Parry S,Mercer BM,Iams J,Wing D,Parker CB,Reddy UM,Wapner RJ,Grobman WA

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Randomized controlled trials that have assessed the efficacy of cervical pessary to prevent preterm birth in asymptomatic high-risk women have reported conflicting results. OBJECTIVE:To evaluate the efficacy and safety of cervical pessary to prevent preterm birth and adverse perinatal outcomes in asymptomat...

journal_title：American journal of obstetrics and gynecology

authors： Conde-Agudelo A,Romero R,Nicolaides KH

更新日期：2020-07-01 00:00:00

abstract：:The National Institutes of Health funding for reproductive sciences research, specifically in academic departments of obstetrics and gynecology, is disproportionately low. Research is one of the most important pillars in advancing healthcare. Despite US Congress' vision in providing increased funding to the National I...

journal_title：American journal of obstetrics and gynecology

authors： Rice LW,Cedars MI,Sadovsky Y,Siddiqui NY,Teal SB,Wright JD,Zorbas A,Del Carmen MG

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVE:This study aimed to conduct a systematic review of the clinical outcomes reported for pregnant patients with coronavirus disease 2019. DATA SOURCES:The PubMed, CINAHL, and Scopus databases were searched using a combination of key words such as "Coronavirus and/or pregnancy," "COVID and/or pregnancy," "COVID ...

journal_title：American journal of obstetrics and gynecology

authors： Della Gatta AN,Rizzo R,Pilu G,Simonazzi G

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVE:The purpose of the present systematic review is to evaluate the available medical treatments for vulvar lichen sclerosus, using an arm-based network meta-analysis protocol. DATA SOURCES:We searched Medline (1966-2019), Scopus (2004-2019), Cochrane Central Register of Controlled Trials CENTRAL (1999-2019), Cl...

journal_title：American journal of obstetrics and gynecology

authors： Pergialiotis V,Bellos I,Biliou EC,Varnava P,Mitsopoulou D,Doumouchtsis SK,CHORUS, an International Collaboration for Harmonising Outcomes, Research and Standards in Urogynaecology and Women's Health (i-chorus.org).

更新日期：2020-06-01 00:00:00

abstract：OBJECTIVE:Defecatory symptoms, such as a sense of incomplete emptying and straining with bowel movements, are paradoxically present in women with fecal incontinence. Treatments for fecal incontinence, such as loperamide and biofeedback, can worsen or improve defecatory symptoms, respectively. The primary aim of this st...

journal_title：American journal of obstetrics and gynecology

authors： Andy UU,Jelovsek JE,Carper B,Meyer I,Dyer KY,Rogers RG,Mazloomdoost D,Korbly NB,Sassani JC,Gantz MG,Pelvic Floor Disorders Network.

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Antecedents of chronic pelvic pain are not well characterized, but pelvic organ visceral sensitivity is a hallmark of these disorders. Recent studies have identified that some dysmenorrhea sufferers are much more likely to exhibit comorbid bladder hypersensitivity. Presumably, these otherwise healthy women m...

journal_title：American journal of obstetrics and gynecology

authors： Tu FF,Datta A,Atashroo D,Senapati S,Roth G,Clauw DJ,Hellman KM

更新日期：2020-06-01 00:00:00