abstract：AIM:To derive an echocardiography-based prognostic score for a 3-year risk of mortality in end-stage renal disease (ESRD) patients undergoing hemodialysis (HD). METHODS:173 ESRD patients hospitalized in the second affiliated hospital of Soochow University from January 1, 2010, to July 31, 2016, were enrolled and follo...

journal_title：Cardiorenal medicine

authors： Zhu J,Tang C,Ouyang H,Shen H,You T,Hu J

更新日期：2020-12-17 00:00:00

abstract：BACKGROUND:The pathophysiology of renal disease progression in autosomal-dominant polycystic kidney disease (ADPKD) involves not only cystogenesis but also endothelial dysfunction, leading to the activation of inflammatory and fibrotic pathways. This study evaluated the levels of biomarkers related to osmoregulation, i...

journal_title：Cardiorenal medicine

authors： Raptis V,Loutradis C,Boutou AK,Faitatzidou D,Sioulis A,Ferro CJ,Papagianni A,Sarafidis PA

更新日期：2020-01-01 00:00:00

abstract：:Coronavirus disease 2019 (COVID-19) is a global pandemic affecting more than 200 countries and 180,000 cases in the United States. While the outbreak began in China, the number of cases outside of China exceeded those in China on March 15, 2020 and are currently rising at an exponential rate. The number of fatalities ...

journal_title：Cardiorenal medicine

authors： Gopalakrishnan A,Mossaid A,Lo KB,Vasudevan V,McCullough PA,Rangaswami J

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:Incremental hemodialysis (HD) is a strategy utilized to gradually intensify dialysis among patients with incident end-stage renal disease. However, there are scarce data about which patients' clinic status changes by increasing treatment frequency. METHODS:We retrospectively examined statistically de-identif...

journal_title：Cardiorenal medicine

authors： Hur I,Wenziger C,Obi Y,Moradi H,Streja E,Tantisattamo E,Choi SJ,Lau WL,Chang Y,Jin A,Chen JLT,Kovesdy CP,Rhee CM,Kalantar-Zadeh K

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Human resistin is a proinflammatory cytokine with significant proatherogenic effects which acts through adenylyl cyclase-associated protein 1 (CAP1). Chronic kidney disease (CKD) and end-stage renal disease (ESRD) patients have increased cardiovascular risk and resistin levels. Previous studies indicated res...

journal_title：Cardiorenal medicine

authors： Munjas J,Sopić M,Bogavac-Stanojević N,Kravljača M,Miljković M,Simić-Ogrizović S,Spasojević-Kalimanovska V,Jelić-Ivanović Z

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Bardoxolone methyl has been shown to increase eGFR in several clinical trials, including a phase 3 trial in patients with type 2 diabetes and stage 4 CKD (BEACON), which was terminated early due to an increase in heart failure events in bardoxolone methyl-treated patients. A separate, "thorough QT" study was...

journal_title：Cardiorenal medicine

authors： Chin MP,Rich S,Goldsberry A,O Apos Grady M,Meyer CJ

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Data on the associations between serum osmolality (sOsmo) and acute kidney injury (AKI) as well as short- and long-term mortality in patients with coronary artery disease (CAD) undergoing percutaneous coronary intervention (PCI) are limited. OBJECTIVES:To investigate the association between sOsmo and develo...

journal_title：Cardiorenal medicine

authors： Farhan S,Vogel B,Baber U,Sartori S,Aquino M,Chandrasekhar J,Sorrentino S,Giustino G,Sharma M,Guedeney P,Rohla M,Bhandari R,Barman N,Sweeny J,Dangas G,Mehran R,Kini A,Sharma S

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:The risk of cardiovascular (CV) complications is much greater in patients with chronic kidney disease (CKD). The aim of this study was to assess predictors of mortality, renal failure progression, and the need for dialysis in patients with CKD. METHODS:The study group consisted of 70 patients with stage 3-5...

journal_title：Cardiorenal medicine

authors： Gromadziński L,Januszko-Giergielewicz B,Czarnacka K,Pruszczyk P

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND/AIMS:Cardiac surgery-associated acute kidney injury (CSA-AKI) is one of the most common postoperative complications in intensive care medicine. Baicalin has been shown to have anti-inflammatory and antioxidant roles in various disorders. We aimed to test the protective effects of baicalin on CSA-AKI using a ...

journal_title：Cardiorenal medicine

authors： Shi J,Wu G,Zou X,Jiang K

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Cardiorenal syndrome type 1 (CRS type 1) is characterized by a rapid worsening of cardiac function leading to acute kidney injury (AKI). Its pathophysiology is complex and not completely understood. In this study, we examined the role of apoptosis and the caspase pathways involved. MATERIAL AND METHODS:We e...

journal_title：Cardiorenal medicine

authors： Breglia A,Virzì GM,Pastori S,Brocca A,de Cal M,Bolin C,Vescovo G,Ronco C

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Statins have long been prescribed for the primary and secondary prevention of cardiovascular disease (CVD) and kidney disease. Their benefits and efficacy are widely accepted in current clinical practice, but like any other therapeutic agents, they have adverse effects. One of the emerging concerns with stat...

journal_title：Cardiorenal medicine

authors： Kamran H,Kupferstein E,Sharma N,Karam JG,Myers AK,Youssef I,Sowers JR,Gustafson DR,Salifu MO,McFarlane SI

更新日期：2018-01-01 00:00:00

abstract：Background/Aims:Contrast-induced nephropathy (CIN) is a typically reversible type of acute renal failure that develops after exposure to contrast agents; underlying endothelial dysfunction is thought to be an important risk factor for CIN. Although the mechanism of coronary collateral circulation (CCC) is not fully und...

journal_title：Cardiorenal medicine

authors： Avci E,Yildirim T,Kadi H

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND/AIMS:Left ventricular hypertrophy and dysfunction are key cardiovascular risk factors of patients on peritoneal dialysis (PD). The purpose of this study was to investigate the dynamic changes of left ventricular (LV) structure and function in patients on long-term PD. METHODS:Patients who underwent PD cathe...

journal_title：Cardiorenal medicine

authors： Shi Q,Zhu J,Feng S,Shen H,Chen J,Song K

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND/AIM:To investigate the role of oxidative stress (OS) in the development of chronic kidney disease (CKD) in atrial fibrillation (AF). METHODS:We compared OS burden, determined at study inclusion as plasma concentrations of oxidized low-density lipoprotein (oxLDL), between stable AF patients (n = 256, mean ag...

journal_title：Cardiorenal medicine

authors： Polovina M,Petrović I,Brković V,Ašanin M,Marinković J,Ostojić M

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND/OBJECTIVE:Post-transplant diabetes mellitus (PTDM) is both common and associated with poor outcomes after kidney transplantation. Our objective was to examine relationships of uremia-associated inflammation and adiponectin with PTDM. METHODS:Nondiabetic kidney transplant patients were enrolled with donor co...

journal_title：Cardiorenal medicine

authors： Cantarin MP,Keith SW,Lin Z,Doria C,Frank AM,Maley WR,Ramirez C,Lallas CD,Shah A,Waldman SA,Falkner B

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:Cardiovascular surgery-associated acute kidney injury (AKI-CS) contributes to mortality and morbidity. However, risk factors accelerating its development are unclear. We identified risk factors for AKI-CS in patients with cardiopulmonary bypass in the hospital surgical intensive care unit to predict and minimiz...

journal_title：Cardiorenal medicine

authors： Yi Q,Li K,Jian Z,Xiao YB,Chen L,Zhang Y,Ma RY

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVE:Patients with end-stage renal disease are susceptible to cardiac valve calcification (CVC) due to mineral metabolism disorders and other factors. The purpose of this study was to investigate the risk factors for new-onset CVC in patients on maintenance peritoneal dialysis (PD). METHODS:This study included pa...

journal_title：Cardiorenal medicine

authors： Tian Y,Feng S,Zhan Z,Lu Y,Wang Y,Jiang S,Song K,Shen H

更新日期：2016-02-01 00:00:00

abstract：AIMS:The purposes of this study were (1) to compare body composition, physical function, and quality of life (QOL) between patients after coronary artery bypass grafting (CABG) with and without chronic kidney disease (CKD) and (2) to analyze the factors associated with physical function and QOL domains in these patient...

journal_title：Cardiorenal medicine

authors： Kuo YT,Chiu KM,Tsang YM,Chiu CM,Chien MY

更新日期：2015-10-01 00:00:00

abstract：AIM:To determine if children and adolescents who have obesity (Ob) or type 2 diabetes (T2DM) of relatively short duration have impaired cardiovascular function compared with lean subjects using 24-hour ambulatory blood pressure as a surrogate measure of evaluation. METHODS:We enrolled 100 African-Caribbean subjects (4...

journal_title：Cardiorenal medicine

authors： Shikha D,Singla M,Walia R,Potter N,Umpaichitra V,Mercado A,Winer N

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Contrast-induced nephropathy (CIN) has been traditionally associated with increased mortality and adverse cardiovascular events. We sought to determine whether CIN has a negative impact on the long-term outcome of patients with non-ST segment elevation myocardial infarction (NSTEMI). METHODS:A total of 312 ...

journal_title：Cardiorenal medicine

authors： Turan B,Erkol A,Gül M,Fındıkçıoğlu U,Erden İ

更新日期：2015-04-01 00:00:00

abstract：:Left ventricular assist devices (LVADs) are used increasingly as a bridge to transplantation or as destination therapy in end-stage heart failure patients who do not respond to optimal medical therapy. Many of these patients have end-organ dysfunction, including advanced kidney dysfunction, before and after LVAD impla...

journal_title：Cardiorenal medicine

authors： Coffin ST,Waguespack DR,Haglund NA,Maltais S,Dwyer JP,Keebler ME

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Cardiorenal syndrome (CRS) is associated with increased cardiovascular morbidity and mortality; still, its biomarker pattern has been poorly evaluated so far. The aim of this study was to measure the inflammatory activation, neurohormonal status and kidney and myocardial damage in patients with CRS compared ...

journal_title：Cardiorenal medicine

authors： Palazzuoli A,Ruocco G,Pellegrini M,Martini S,Del Castillo G,Beltrami M,Franci B,Lucani B,Nuti R

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:In adults, both obesity and type 2 diabetes mellitus (T2DM) are positively correlated with cardiovascular disease mortality and arterial stiffness. Several studies of adults have shown that both obesity and T2DM are independently associated with increased arterial stiffness. However, little is known about th...

journal_title：Cardiorenal medicine

authors： Shikha D,Singla M,Walia R,Potter N,Mercado A,Winer N

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Many patients admitted to a Department of Internal Medicine have different degrees of heart and kidney dysfunction. Mortality, morbidity and cost of care greatly increase when cardiac and renal diseases coexist. METHODS:A retrospective cohort study was conducted on 1,087 patients admitted from December 2009...

journal_title：Cardiorenal medicine

authors： Gigante A,Liberatori M,Gasperini ML,Sardo L,Di Mario F,Dorelli B,Barbano B,Rosato E,Rossi Fanelli F,Amoroso A

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Intraoperative hemolysis and inflammation are associated with acute kidney injury (AKI) following cardiac surgery. Plasma-free hemoglobin induces heme oxygenase-1 (HO-1) expression. HO-1 degrades heme but increases in experimental models of AKI. This study tested the hypothesis that plasma HO-1 concentration...

journal_title：Cardiorenal medicine

authors： Billings FT 4th,Yu C,Byrne JG,Petracek MR,Pretorius M

更新日期：2014-04-01 00:00:00

abstract：:Sixty-six self-identified African-American subjects with stage 1 and 2 hypertension and characteristics of the cardiometabolic syndrome were treated with amlodipine/olmesartan (A/O) versus losartan/hydrochlorothiazide (L/H) for 20 weeks in an open-label, active comparator fashion. Subjects not meeting a blood pressure...

journal_title：Cardiorenal medicine

authors： Khan BV,Merchant N,Rahman ST,Ahmad M,Parrott JM,Umar K,Johnson J,Ferdinand KC

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Several methods have been developed to assess the hydration status in chronic hemodialysis (HD) patients. The aim of this study was to compare body bioimpedance spectroscopy (BIS) with ultrasound (US) lung comet score (ULCs), B-type natriuretic peptide (BNP) and inferior vena cava diameter (IVCD) by US for t...

journal_title：Cardiorenal medicine

authors： Basso F,Milan Manani S,Cruz DN,Teixeira C,Brendolan A,Nalesso F,Zanella M,Ronco C

更新日期：2013-07-01 00:00:00

abstract：:Periodontal disease is a chronic inflammatory disorder and being so it has been associated with accelerated atherosclerosis and malnutrition. Cardiovascular diseases are the leading cause of mortality in chronic kidney disease (CKD) and end-stage renal disease (ESRD) patients [National Institutes of Health, National I...

journal_title：Cardiorenal medicine

authors： Ariyamuthu VK,Nolph KD,Ringdahl BE

更新日期：2013-04-01 00:00:00

abstract：:Since the classic experiments by Tigerstedt and Bergman that established the role of renin in hypertension a century ago, aggressive efforts have been launched to effectively block the renin-angiotensin system (RAS). Blockade of RAS is advocated at multiple levels by direct renin inhibitor, angiotensin-converting enzy...

journal_title：Cardiorenal medicine

authors： Gul R,Ramdas M,Mandavia CH,Sowers JR,Pulakat L

更新日期：2012-12-01 00:00:00

abstract：:Insulin (INS) metabolic signaling is important for normal cardiovascular and renal function as well as for exerting the classic actions of INS, such as glucose uptake in skeletal muscle tissue. There is emerging evidence that tyrosine phosphatases as well as protein kinases have important modulating roles in INS metab...

journal_title：Cardiorenal medicine

authors： Mandavia C,Sowers JR

更新日期：2012-12-01 00:00:00

abstract：:BACKGROUND: Vitamin D deficiency and secondary rises in parathyroid hormone (PTH) are highly prevalent in obese African-Americans. Endothelial dysfunction related to oxidative stress is more common in African-Americans compared to whites. Currently, the association of vitamin D (25-hydroxyvitamin D, 25-OH D) and PTH t...

journal_title：Cardiorenal medicine

authors： Valiña-Tóth AL,Lai Z,Zhang S,Flack JM

更新日期：2012-08-01 00:00:00

abstract：:The key role of chronic inflammation in the pathogenesis of atherosclerosis has become increasingly apparent in recent years based on the results of experimental, epidemiologic and clinical studies. Coronary artery disease and its complications occur with disproportionately high frequency in patients with end-stage re...

journal_title：Cardiorenal medicine

authors： Nusair MB,Rajpurohit N,Alpert MA

更新日期：2012-05-01 00:00:00

abstract：:BACKGROUND/AIMS: Arsenic (As) is linked to insulin resistance in animal studies, but the effect of low-level As exposure on the prevalence of diabetes in humans is uncertain. An optimal method to report inorganic As in humans has not been established. Measurements of As in spot urine are usually adjusted to creatinine...

journal_title：Cardiorenal medicine

authors： Yassine H,Kimzey MJ,Galligan MA,Gandolfi AJ,Stump CS,Lau SS

更新日期：2012-02-01 00:00:00

abstract：:Malnutrition and inflammation are strong predictors of mortality in advanced kidney disease, especially in patients on renal replacement therapy. The complex relationship between kidney disease, uremia, and malnutrition significantly contributes to the increased morbidity and mortality in this patient population poten...

journal_title：Cardiorenal medicine

authors： Gupta D,Gardner M,Whaley-Connell A

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND/AIMS:Renal dysfunction is associated with a higher risk of cardiovascular disease in patients with acute myocardial infarction (AMI). The aim of this study was to investigate the independent prognostic value of renal dysfunction and its incremental predictability risk after adjusting for well-known clinical ...

journal_title：Cardiorenal medicine

authors： Blasco L,Sanjuan R,Carbonell N,Solís MA,Puchades MJ,Torregrosa I,Miguel JA

更新日期：2011-01-01 00:00:00

abstract：:Metformin and asymmetric dimethylarginine (ADMA) are structural analogs. They have opposite effects at multiple points on complex signaling pathways that coordinate energy, molecular synthesis, growth, and metabolism with nutrient intake. Excess saturated fats and glucose may initiate the methylation of arginine resid...

journal_title：Cardiorenal medicine

authors： Bestermann WH Jr

更新日期：2011-01-01 00:00:00