听力与言语-语言病理学

行为科学

医学伦理学

你正在浏览Journal of Ginseng Research期刊下所有文献
  • Purification of ginseng rare sapogenins 25-OH-PPT and its hypoglycemic, antiinflammatory and lipid-lowering mechanisms.

    abstract:Background:Panax ginseng Meyer has been used as a nourishing edible herb in East Asia for thousands of years. 25-OH-PPT was first discovered as a natural rare triterpenoid saponin in ginseng stems and leaves by our group. Research found that it showed strong inhibitory effects on α-glucosidase and protein tyrosine phos...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2019.11.002

    authors: Xu J,Liu H,Su G,Ding M,Wang W,Lu J,Bi X,Zhao Y

    更新日期:2021-01-01 00:00:00

  • Anti-aging effects of Korean Red Ginseng (KRG) in differentiated embryo chondrocyte (DEC) knockout mice.

    abstract:Background:The circadian rhythm is the internal clock that controls sleep-wake cycles, metabolism, cognition, and several processes in the body, and its disruption has been associated with aging. The differentiated embryo chondrocyte (Dec) gene is related to circadian rhythm. To our knowledge, there are no reports of t...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2020.09.003

    authors: Nam YH,Jeong SY,Kim YH,Rodriguez I,Nuankaew W,Bhawal UK,Hong BN,Kang TH

    更新日期:2021-01-01 00:00:00

  • Analysis of oligosaccharides from Panax ginseng by using solid-phase permethylation method combined with ultra-high-performance liquid chromatography-Q-Orbitrap/mass spectrometry.

    abstract:Background:The reports about valuable oligosaccharides in ginseng are quite limited. There is an urgent need to develop a practical procedure to detect and analyze ginseng oligosaccharides. Methods:The oligosaccharide extracts from ginseng were permethylated by solid-phase methylation method and then were analyzed by ...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2019.08.001

    authors: Li L,Ma L,Guo Y,Liu W,Wang Y,Liu S

    更新日期:2020-11-01 00:00:00

  • Ginsenoside Rh2 attenuates microglial activation against toxoplasmic encephalitis via TLR4/NF-κB signaling pathway.

    abstract:Background:Ginsenoside Rh2 (GRh2) is a characterized component in red ginseng widely used in Korea and China. GRh2 exhibits a wide range of pharmacological activities, such as anti-inflammatory, antioxidant, and anticancer properties. However, its effects on Toxoplasma gondii (T. gondii) infection have not been clarifi...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2019.06.002

    authors: Xu X,Jin L,Jiang T,Lu Y,Aosai F,Piao HN,Xu GH,Jin CH,Jin XJ,Ma J,Piao LX

    更新日期:2020-09-01 00:00:00

  • Antidepressant effects of ginsenoside Rf on behavioral change in the glial degeneration model of depression by reversing glial loss.

    abstract:Background:Depression is a common neuropsychiatric disease that shows astrocyte pathology. Ginsenoside Rf (G-Rf) is a saponin found in Panax ginseng which has been used to treat neuropsychiatric diseases. We aimed to investigate antidepressant properties of G-Rf when introduced into the L-alpha-aminoadipic acid (L-AAA)...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2019.08.005

    authors: Kim Y,Lee HY,Choi YJ,Cho SH

    更新日期:2020-07-01 00:00:00

  • Ginsenosides: potential therapeutic source for fibrosis-associated human diseases.

    abstract::Tissue fibrosis is an eventual pathologic change of numerous chronic illnesses, which is characterized by resident fibroblasts differentiation into myofibroblasts during inflammation, coupled with excessive extracellular matrix deposition in tissues, ultimately leading to failure of normal organ function. Now, there a...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章,评审

    doi:10.1016/j.jgr.2019.12.003

    authors: Li X,Mo N,Li Z

    更新日期:2020-05-01 00:00:00

  • Korean Red Ginseng enhances cardiac hemodynamics on doxorubicin-induced toxicity in rats.

    abstract:Background:Korean Red Ginseng (KRG) has been known to possess many ginsenosides. These ginsenosides are used for curing cardiovascular problems. The present study show the protective potential of KRG against doxorubicin (DOX)-induced myocardial dysfunction, by assessing electrocardiographic, hemodynamic, and biochemica...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2019.03.002

    authors: Jang YJ,Lee D,Hossain MA,Aravinthan A,Kang CW,Kim NS,Kim JH

    更新日期:2020-05-01 00:00:00

  • Ginseng alleviates microbial infections of the respiratory tract: a review.

    abstract::The detrimental impact of air pollution as a result of frequent exposure to fine particles posed a global public health risk mainly to the pulmonary disorders in pediatric and geriatric population. Here, we reviewed the current literature regarding the role of ginseng and/or its components as antimicrobials, especiall...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章,评审

    doi:10.1016/j.jgr.2019.12.001

    authors: Iqbal H,Rhee DK

    更新日期:2020-03-01 00:00:00

  • Ginseng berry polysaccharides on inflammation-associated colon cancer: inhibiting T-cell differentiation, promoting apoptosis, and enhancing the effects of 5-fluorouracil.

    abstract:Background:Ginseng is a commonly used herbal medicine in treating various medical conditions. Chronic gut inflammation is a recognized factor for the development of colorectal cancer (CRC). In this project, Asian ginseng berry polysaccharide preparations were used to assess their effects on CRC and related immune regul...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2018.12.010

    authors: Wang CZ,Hou L,Wan JY,Yao H,Yuan J,Zeng J,Park CW,Kim SH,Seo DB,Shin KS,Zhang CF,Chen L,Zhang QH,Liu Z,Sava-Segal C,Yuan CS

    更新日期:2020-03-01 00:00:00

  • Fermented ginseng extract, BST204, disturbs adipogenesis of mesenchymal stem cells through inhibition of S6 kinase 1 signaling.

    abstract:Background:The biological and pharmacological effects of BST204, a fermented ginseng extract, have been reported in various disease conditions. However, its molecular action in metabolic disease remains poorly understood. In this study, we identified the antiadipogenic activity of BST204 resulting from its inhibition o...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2018.08.002

    authors: Yi SA,Lee J,Park SK,Kim JY,Park JW,Lee MG,Nam KH,Park JH,Oh H,Kim S,Han J,Kim BK,Jo DG,Han JW

    更新日期:2020-01-01 00:00:00

  • Ginseng extracts modulate mitochondrial bioenergetics of live cardiomyoblasts: a functional comparison of different extraction solvents.

    abstract:Background:The root of Panax ginseng, a member of Araliaceae family, has been used as herbal medicine and functional food in Asia for thousands of years. According to Traditional Chinese medicine, ginseng is the most widely used "Qi-invigorating" herbs, which provides tonic and preventive effects by resisting oxidative...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2018.02.002

    authors: Huang Y,Kwan KKL,Leung KW,Yao P,Wang H,Dong TT,Tsim KWK

    更新日期:2019-10-01 00:00:00

  • Overexpression of ginseng cytochrome P450 CYP736A12 alters plant growth and confers phenylurea herbicide tolerance in Arabidopsis.

    abstract:Background:Cytochrome P450 enzymes catalyze a wide range of reactions in plant metabolism. Besides their physiological functions on primary and secondary metabolites, P450s are also involved in herbicide detoxification via hydroxylation or dealkylation. Ginseng as a perennial plant offers more sustainable solutions to ...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2019.04.005

    authors: Khanom S,Jang J,Lee OR

    更新日期:2019-10-01 00:00:00

  • Ginsenoside Rg3 and Korean Red Ginseng extract epigenetically regulate the tumor-related long noncoding RNAs RFX3-AS1 and STXBP5-AS1.

    abstract:Background:Ginsenoside Rg3, a derivative of steroidal saponins abundant in ginseng, has a range of effects on cancer cells, including anti-cell proliferation and anti-inflammation activity. Here, we investigate two long noncoding RNAs (lncRNAs), STXBP5-AS1 and RFX3-AS1, which are hypomethylated and hypermethylated in t...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2019.02.004

    authors: Ham J,Jeong D,Park S,Kim HW,Kim H,Kim SJ

    更新日期:2019-10-01 00:00:00

  • Chemical and bioactive comparison of Panax notoginseng root and rhizome in raw and steamed forms.

    abstract:Background:The root and rhizome are historically and officially utilized medicinal parts of Panax notoginseng (PN) (Burk.) F. H. Chen, which in raw and steamed forms are used differently in practice. Methods:To investigate the differences in chemical composition and bioactivities of PN root and rhizome between raw and...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2017.11.004

    authors: Xiong Y,Chen L,Man J,Hu Y,Cui X

    更新日期:2019-07-01 00:00:00

  • Molecular discrimination of Panax ginseng cultivar K-1 using pathogenesis-related protein 5 gene.

    abstract:Background:The mixed-cultivation of different Panax ginseng cultivars can cause adverse effects on stability of yield and quality. K-1 is a superior cultivar with good root shape and stronger disease resistance. DNA markers mined from functional genes are clearly desirable for K-1, as they may associate with major trai...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2018.07.001

    authors: Wang H,Xu F,Wang X,Kwon WS,Yang DC

    更新日期:2019-07-01 00:00:00

  • The effect of Korean Red Ginseng on full-thickness skin wound healing in rats.

    abstract:Background:Panax ginseng is regarded as one of the best compounds for promoting health, and it has been used traditionally as a medicinal herb. Recently, Korean Red Ginseng (RG) has been shown to protect skin from aging and wrinkling; it can also relieve atopic dermatitis and allergy symptoms. This study aimed to evalu...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2017.12.006

    authors: Park KS,Park DH

    更新日期:2019-04-01 00:00:00

  • Ginsenoside Rf inhibits cyclooxygenase-2 induction via peroxisome proliferator-activated receptor gamma in A549 cells.

    abstract:Background:Ginsenoside Rf is a ginseng saponin found only in Panax ginseng that affects lipid metabolism. It also has neuroprotective and antiinflammatory properties. We previously showed that Korean Red Ginseng (KRG) inhibited the expression of cyclooxygenase-2 (COX-2) by hypoxia via peroxisome proliferator-activated ...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2018.11.007

    authors: Song H,Park J,Choi K,Lee J,Chen J,Park HJ,Yu BI,Iida M,Rhyu MR,Lee Y

    更新日期:2019-04-01 00:00:00

  • Fermentation of red ginseng extract by the probiotic Lactobacillus plantarum KCCM 11613P: ginsenoside conversion and antioxidant effects.

    abstract:Background:Ginsenosides, which are bioactive components in ginseng, can be converted to smaller compounds for improvement of their pharmacological activities. The conversion methods include heating; acid, alkali, and enzymatic treatment; and microbial conversion. The aim of this study was to determine the bioconversion...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2017.07.004

    authors: Jung J,Jang HJ,Eom SJ,Choi NS,Lee NK,Paik HD

    更新日期:2019-01-01 00:00:00

  • Biosynthesis of rare 20(R)-protopanaxadiol/protopanaxatriol type ginsenosides through Escherichia coli engineered with uridine diphosphate glycosyltransferase genes.

    abstract:Background:Ginsenosides are known as the principal pharmacological active constituents in Panax medicinal plants such as Asian ginseng, American ginseng, and Notoginseng. Some ginsenosides, especially the 20(R) isomers, are found in trace amounts in natural sources and are difficult to chemically synthesize. The presen...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2017.09.005

    authors: Yu L,Chen Y,Shi J,Wang R,Yang Y,Yang L,Zhao S,Wang Z

    更新日期:2019-01-01 00:00:00

  • Ginseng seed oil ameliorates hepatic lipid accumulation in vitro and in vivo.

    abstract:Background:Despite the large number of studies on ginseng, pharmacological activities of ginseng seed oil (GSO) have not been established. GSO is rich in unsaturated fatty acids, mostly oleic and linoleic acids. Unsaturated fatty acids are known to exert a therapeutic effect in nonalcoholic fatty liver disease (NAFLD)....

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2017.04.010

    authors: Kim GW,Jo HK,Chung SH

    更新日期:2018-10-01 00:00:00

  • Panax ginseng as an adjuvant treatment for Alzheimer's disease.

    abstract::Longevity in medicine can be defined as a long life without mental or physical deficits. This can be prevented by Alzheimer's disease (AD). Current conventional AD treatments only alleviate the symptoms without reversing AD progression. Recent studies demonstrated that Panax ginseng extract improves AD symptoms in pat...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章,评审

    doi:10.1016/j.jgr.2017.12.008

    authors: Kim HJ,Jung SW,Kim SY,Cho IH,Kim HC,Rhim H,Kim M,Nah SY

    更新日期:2018-10-01 00:00:00

  • AKT-targeted anti-inflammatory activity of Panax ginseng calyx ethanolic extract.

    abstract:Background:Korean ginseng (Panax ginseng) plays an anti-inflammatory role in a variety of inflammatory diseases such as gastritis, hepatitis, and colitis. However, inflammation-regulatory activity of the calyx of the P. ginseng berry has not been thoroughly evaluated. To understand whether the calyx portion of the P. g...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2017.06.003

    authors: Han SY,Kim J,Kim E,Kim SH,Seo DB,Kim JH,Shin SS,Cho JY

    更新日期:2018-10-01 00:00:00

  • Korean Red Ginseng extract reduces hypoxia-induced epithelial-mesenchymal transition by repressing NF-κB and ERK1/2 pathways in colon cancer.

    abstract:Background:The incidence of colorectal cancer (CRC) is increasing, with metastasis of newly diagnosed CRC reported in a large proportion of patients. However, the effect of Korean Red Ginseng extracts (KRGE) on epithelial to mesenchymal transition (EMT) in CRC is unknown. Therefore, we examined the mechanisms by which ...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2017.03.008

    authors: Kim EJ,Kwon KA,Lee YE,Kim JH,Kim SH,Kim JH

    更新日期:2018-07-01 00:00:00

  • Antimelanogenesis and skin-protective activities of Panax ginseng calyx ethanol extract.

    abstract:Background:The antioxidant effects of Panax ginseng have been reported in several articles; however, little is known about the antimelanogenesis effect, skin-protective effect, and cellular mechanism of Panax ginseng, especially of P. ginseng calyx. To understand how an ethanol extract of P. ginseng berry calyx (Pg-C-E...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2018.02.007

    authors: Lee JO,Kim E,Kim JH,Hong YH,Kim HG,Jeong D,Kim J,Kim SH,Park C,Seo DB,Son YJ,Han SY,Cho JY

    更新日期:2018-07-01 00:00:00

  • Ginsenoside Rg1 modulates medial prefrontal cortical firing and suppresses the hippocampo-medial prefrontal cortical long-term potentiation.

    abstract:Background:Panax ginseng is one of the most commonly used medicinal herbs worldwide for a variety of therapeutic properties including neurocognitive effects. Ginsenoside Rg1 is one of the most abundant active chemical constituents of this herb with known neuroprotective, anxiolytic, and cognition improving effects. Me...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2017.03.010

    authors: Ghaeminia M,Rajkumar R,Koh HL,Dawe GS,Tan CH

    更新日期:2018-07-01 00:00:00

  • Korean Red Ginseng exhibits no significant adverse effect on disease activity in patients with rheumatoid arthritis: a randomized, double-blind, crossover study.

    abstract:Background:Panax ginseng is a well-known immune modulator, and there is concern that its immune-enhancing effects may negatively affect patients with rheumatoid arthritis (RA) by worsening symptoms or increasing the risk of adverse effects from other drugs. In this randomized, crossover clinical trial, we evaluated the...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2017.01.006

    authors: Cho SK,Kim D,Yoo D,Jang EJ,Jun JB,Sung YK

    更新日期:2018-04-01 00:00:00

  • Ginsenoside Rg5 prevents apoptosis by modulating heme-oxygenase-1/nuclear factor E2-related factor 2 signaling and alters the expression of cognitive impairment-associated genes in thermal stress-exposed HT22 cells.

    abstract::Our results suggested that thermal stress can lead to activation of hippocampal cell damage and reduction of memory-associated molecules in HT22 cells. These findings also provide a part of molecular rationale for the role of ginsenoside Rg5 as a potent cognitive impairment preventive compound in blocking the initiati...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2017.02.002

    authors: Choi SY,Kim KJ,Song JH,Lee BY

    更新日期:2018-04-01 00:00:00

  • Gintonin absorption in intestinal model systems.

    abstract:Background:Recently, we identified a novel ginseng-derived lysophosphatidic acid receptor ligand, called gintonin. We showed that gintonin induces [Ca2+]i transient-mediated morphological changes, proliferation, and migration in cells expressing lysophosphatidic acid receptors and that oral administration of gintonin e...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2016.12.007

    authors: Lee BH,Choi SH,Kim HJ,Park SD,Rhim H,Kim HC,Hwang SH,Nah SY

    更新日期:2018-01-01 00:00:00

  • Black ginseng activates Akt signaling, thereby enhancing myoblast differentiation and myotube growth.

    abstract:Background:Black ginseng (BG) has greatly enhanced pharmacological activities relative to white or red ginseng. However, the effect and molecular mechanism of BG on muscle growth has not yet been examined. In this study, we investigated whether BG could regulate myoblast differentiation and myotube hypertrophy. Method...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2017.08.009

    authors: Lee SY,Go GY,Vuong TA,Kim JW,Lee S,Jo A,An JM,Kim SN,Seo DW,Kim JS,Kim YK,Kang JS,Lee SJ,Bae GU

    更新日期:2018-01-01 00:00:00

  • Effect of Korean Red Ginseng in chronic liver disease.

    abstract::Chronic liver disease, one of the most common diseases, typically arises from nonalcoholic fatty liver disease, alcoholic liver disease, chronic viral hepatitis, or hepatocellular carcinoma. Therefore, there is a pressing need for improved treatment strategies. Korean Red Ginseng has been known to have positive effect...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章,评审

    doi:10.1016/j.jgr.2016.11.004

    authors: Park TY,Hong M,Sung H,Kim S,Suk KT

    更新日期:2017-10-01 00:00:00

  • Ginsenoside Rg12, a new dammarane-type triterpene saponin from Panax ginseng root.

    abstract:BACKGROUND:Panax ginseng has been used as Korean medicine for various diseases. It has antioxidant, hypotensive, sedative, analgesic, and endocrine activities. Dammarane-type triterpenes from the plant have various beneficial effects. METHODS:A dammarane-type triterpene saponin was isolated from P. ginseng root throug...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2016.10.002

    authors: Lee DG,Lee J,Cho IH,Kim HJ,Lee SW,Kim YO,Park CG,Lee S

    更新日期:2017-10-01 00:00:00

  • Melanogenesis inhibition activity of floralginsenoside A from Panax ginseng berry.

    abstract:BACKGROUND:Panax ginseng is a traditional herb used for medicinal purposes in eastern Asia. P. ginseng contains various ginsenosides with pharmacological effects. In this study, floralginsenoside A (FGA), ginsenoside Rd (GRD), and ginsenoside Re (GRE) were purified from P. ginseng berry. METHODS:Chemical structures of...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2017.03.005

    authors: Lee DY,Lee J,Jeong YT,Byun GH,Kim JH

    更新日期:2017-10-01 00:00:00

  • Nuclear factor kappa-B- and activator protein-1-mediated immunostimulatory activity of compound K in monocytes and macrophages.

    abstract:BACKGROUND:Compound K (CK) is a bioactive derivative of ginsenoside Rb1 in Panax ginseng (Korean ginseng). Its biological and pharmacological activities have been studied in various disease conditions, although its immunomodulatory role in innate immunity mediated by monocytes/macrophages has been poorly understood. In...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2016.06.004

    authors: Yang WS,Yi YS,Kim D,Kim MH,Park JG,Kim E,Lee SY,Yoon K,Kim JH,Park J,Cho JY

    更新日期:2017-07-01 00:00:00

  • Discovery, semisynthesis, biological activities, and metabolism of ocotillol-type saponins.

    abstract::Ocotillol-type saponins are one kind of tetracyclic triterpenoids, sharing a tetrahydrofuran ring. Natural ocotillol-type saponins have been discovered in Panax quinquefolius L., Panax japonicus, Hana mina, and Vietnamese ginseng. In recent years, the semisynthesis of 20(S/R)-ocotillol-type saponins has been reported....

    journal_title:Journal of ginseng research

    pub_type: 杂志文章,评审

    doi:10.1016/j.jgr.2017.01.001

    authors: Liu J,Xu Y,Yang J,Wang W,Zhang J,Zhang R,Meng Q

    更新日期:2017-07-01 00:00:00

  • Panax ginseng Meyer prevents radiation-induced liver injury via modulation of oxidative stress and apoptosis.

    abstract:BACKGROUND:Radiotherapy is one of the most important modalities in cancer treatment; however, normal tissue damage is a serious concern. Drug development for the protection or reduction of normal tissue damage is therefore a clinical issue. Herein, we evaluated the protective properties of Panax ginseng Meyer and its c...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2016.02.006

    authors: Kim HG,Jang SS,Lee JS,Kim HS,Son CG

    更新日期:2017-04-01 00:00:00

  • Biotransformation of major ginsenosides in ginsenoside model culture by lactic acid bacteria.

    abstract:BACKGROUND:Some differences have been reported in the biotransformation of ginsenosides, probably due to the types of materials used such as ginseng, enzymes, and microorganisms. Moreover, most microorganisms used for transforming ginsenosides do not meet food-grade standards. We investigated the statistical conversion...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2015.12.008

    authors: Park SE,Na CS,Yoo SA,Seo SH,Son HS

    更新日期:2017-01-01 00:00:00

  • Effect of Red Ginseng on cytochrome P450 and P-glycoprotein activities in healthy volunteers.

    abstract:BACKGROUND:We evaluated the drug interaction profile of Red Ginseng (RG) with respect to the activities of major cytochrome P450 (CYP) enzymes and the drug transporter P-glycoprotein (P-gp) in healthy Korean volunteers. METHODS:This article describes an open-label, crossover study. CYP probe cocktail drugs, caffeine, ...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2015.11.005

    authors: Kim DS,Kim Y,Jeon JY,Kim MG

    更新日期:2016-10-01 00:00:00

  • Complete (1)H-NMR and (13)C-NMR spectral assignment of five malonyl ginsenosides from the fresh flower buds of Panax ginseng.

    abstract:BACKGROUND:Ginsenosides are the major effective ingredients responsible for the pharmacological effects of ginseng. Malonyl ginsenosides are natural ginsenosides that contain a malonyl group attached to a glucose unit of the corresponding neutral ginsenosides. METHODS:Medium-pressure liquid chromatography and semiprep...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2015.08.003

    authors: Wang YS,Jin YP,Gao W,Xiao SY,Zhang YW,Zheng PH,Wang J,Liu JX,Sun CH,Wang YP

    更新日期:2016-07-01 00:00:00

  • Enzymatic formation of compound-K from ginsenoside Rb1 by enzyme preparation from cultured mycelia of Armillaria mellea.

    abstract:BACKGROUND:Minor saponins or human intestinal bacterial metabolites, such as ginsenosides Rg3, F2, Rh2, and compound K, are more pharmacologically active than major saponins, such as ginsenosides Rb1, Rb2, and Rc. In this work, enzymatic hydrolysis of ginsenoside Rb1 was studied using enzyme preparations from cultured ...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2015.05.007

    authors: Upadhyaya J,Kim MJ,Kim YH,Ko SR,Park HW,Kim MK

    更新日期:2016-04-01 00:00:00

  • Pectinase-treated Panax ginseng ameliorates hydrogen peroxide-induced oxidative stress in GC-2 sperm cells and modulates testicular gene expression in aged rats.

    abstract:BACKGROUND:To investigate the effect of pectinase-treated Panax ginseng (GINST) in cellular and male subfertility animal models. METHODS:Hydrogen peroxide (H2O2)-induced mouse spermatocyte GC-2spd cells were used as an in vitro model. Cell viability was measured using MTT assay. For the in vivo study, GINST (200 mg/kg...

    journal_title:Journal of ginseng research

    pub_type: 杂志文章

    doi:10.1016/j.jgr.2015.08.005

    authors: Kopalli SR,Cha KM,Jeong MS,Lee SH,Sung JH,Seo SK,Kim SK

    更新日期:2016-04-01 00:00:00

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