abstract：:Nickel (Ni) oral hyposensitization treatment (NiOHT) is an effective management approach for Ni allergy. No health-related quality of life (HRQoL) data exist for the pre- and post-treatment with NiOHT in systemic nickel allergy syndrome (SNAS). The aims of this study were (a) to explore HRQoL in SNAS patients, (b) to ...

journal_title：International journal of immunopathology and pharmacology

authors： Rizzi A,Di Rienzo A,Buonomo A,Aruanno A,Carusi V,Ricci AG,Centrone M,Mezzacappa S,Romeo L,Schiavino D,Inchingolo R,Gasbarrini A,Nucera E

更新日期：2020-01-01 00:00:00

abstract：:Atopic dermatitis (AD) is a chronic inflammatory disease of the skin that substantially affects a patient's quality of life. While steroids are the most common therapy used to temporally alleviate the symptoms of AD, effective and nontoxic alternatives are urgently needed. In this study, we utilized a natural, plant-d...

journal_title：International journal of immunopathology and pharmacology

authors： Wu CS,Lin SC,Li S,Chiang YC,Bracci N,Lehman CW,Tang KT,Lin CC

更新日期：2020-01-01 00:00:00

abstract：:Varicocele is a common cause of sperm damage. Some studies showed higher concentration of seminal leukocytes in patients with varicocele. The aim of the study was to evaluate seminal leukocyte subpopulations in patients with varicocele. We enrolled 20 patients with varicocele and 20 age-matched healthy men. Sperm anal...

journal_title：International journal of immunopathology and pharmacology

authors： Mongioì LM,Alamo A,Calogero AE,Compagnone M,Giacone F,Cannarella R,La Vignera S,Condorelli RA

更新日期：2020-01-01 00:00:00

abstract：:The narrow therapeutic index and large inter-individual variability in sirolimus pharmacokinetics (PK) make therapeutic drug monitoring (TDM) necessary. Factors responsible for PK variability are not well understood, and published PK studies do not include pediatric patients with immune cytopenia. The objective of thi...

journal_title：International journal of immunopathology and pharmacology

authors： Cheng X,Zhao Y,Gu H,Zhao L,Zang Y,Wang X,Wu R

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION:Indoleamine 2,3-dioxygenase (IDO) was a potential tumor immunotherapy target. IDO inhibitors showed inconsistent results in clinical trials, but no preclinical comparative study was reported. The purpose of this study was to evaluate the differences of representative IDO inhibitors (PCC0208009, INCB024360,...

journal_title：International journal of immunopathology and pharmacology

authors： Jiang X,Li X,Zheng S,Du G,Ma J,Zhang L,Wang H,Tian J

更新日期：2020-01-01 00:00:00

abstract：:Myrcene (MC), an organic hydrocarbon, was found to exert anti-inflammatory, analgesic, antimutagenic and antioxidant properties. However, the protective role of MC has not been reported against neonatal asthma. Wistar rats induced with asthma were administered with MC; while asthma control and vehicle control were mai...

journal_title：International journal of immunopathology and pharmacology

authors： Du Y,Luan J,Jiang RP,Liu J,Ma Y

更新日期：2020-01-01 00:00:00

abstract：:Septic shock (SS) leads to a high mortality rate for sepsis patients. Norepinephrine (NE) is a preferred vasoactive agent in SS treatment. This study aimed to assess the effects of NE at different administration time and NE combined with SP treatment on the cardiac function and prognosis of SS.SS patients received NE ...

journal_title：International journal of immunopathology and pharmacology

authors： Kang D,Yu J,Xia J,Li X,Wang H,Zhao Y

更新日期：2020-01-01 00:00:00

abstract：:This study aimed to investigate the clinical significance of serum microRNA-219-5p (miR-219-5p) in patients with multiple organ dysfunction syndrome (MODS) caused by acute paraquat (PQ) poisoning, and its correlation with Toll-like Receptor 4 (TLR4). Luciferase reporter assay was used to investigate in vitro the corre...

journal_title：International journal of immunopathology and pharmacology

authors： Dai Y,Liu X,Gao Y

更新日期：2020-01-01 00:00:00

abstract：:Calligonum polygonoides is locally called as Phog which belongs to the Polygonaceae family. It is traditionally used as an antifungal. The methanolic extract, hexane extract, ethyl acetate extract and aqueous extract were screened against Candida albicans and Aspergillus niger in seven concentrations, that is, 1.8, 2....

journal_title：International journal of immunopathology and pharmacology

authors： Ahmad S,Akram M

更新日期：2019-01-01 00:00:00

abstract：:The autoptical observations commonly ascribed to sepsis deal with unspecific general and local signs of inflammation or ischemia, such as myocardial inflammation, pulmonary edema and infiltration, cerebral swallowing, and tubular necrosis in the kidney. In the two last decades, some studies have been carried out to im...

journal_title：International journal of immunopathology and pharmacology

authors： La Russa R,Maiese A,Viola RV,De Matteis A,Pinchi E,Frati P,Fineschi V

更新日期：2019-01-01 00:00:00

abstract：:We aimed to analyze the action of berberine on the neuropathic pain and neuroglia activation in experimental diabetes mellitus (DM) model. Diabetes in mice was induced by intraperitoneal injection of streptozotocin (STZ) followed by the administration of berberine. Mechanical allodynia and thermal hyperalgesia and act...

journal_title：International journal of immunopathology and pharmacology

authors： Liu M,Gao L,Zhang N

更新日期：2019-01-01 00:00:00

abstract：:It is of significance to alleviate oxidative damages for the treatment of spinal cord injury (SCI). Studies have ascertained that green tea polyphenols (GTPs) exert protective activities against oxidative damages. In this study, we aimed to investigate the protective effects of GTP against H2O2-caused injuries in PC12...

journal_title：International journal of immunopathology and pharmacology

authors： Liu S,Yu G,Song G,Zhang Q

更新日期：2019-01-01 00:00:00

abstract：:Orofacial clefts are common congenital defects whose prevalence differs between geographical regions and ethnic groups. The inheritance is complex, involving the contribution of both genetic and environmental factors. The involvement of genes belonging to the folate pathway is still matter of debate, with strong evide...

journal_title：International journal of immunopathology and pharmacology

authors： Carinci F,Palmieri A,Scapoli L,Cura F,Abenavoli F,Giannì AB,Russillo A,Docimo R,Martinelli M

更新日期：2019-01-01 00:00:00

abstract：:In recent decades, the role played by the immune response to bacteria in the pathogenesis of chronic periodontal disease (PD) has long been studied. Although from the clinical point of view, adequate oral hygiene is essential to ensure a satisfactory response of the host to infections, modulation of the reaction of im...

journal_title：International journal of immunopathology and pharmacology

authors： Luca S,Francesco C,Damiano M,Alessandro N,Silvia C,Diego R,Michele R,Marco S

更新日期：2019-01-01 00:00:00

abstract：:There is still no "gold standard" for the diagnosis and prognosis of post-operative periprosthetic joint infection (PJI). Among serum biomarkers, an emerging molecule is presepsin, the soluble fraction of CD14, recently described in other settings as a powerful diagnostic tool to detect sepsis at different degrees of ...

journal_title：International journal of immunopathology and pharmacology

authors： Marazzi MG,Randelli F,Brioschi M,Drago L,Romanò CL,Banfi G,Massaccesi L,Crapanzano C,Morelli F,Corsi Romanelli MM,Galliera E

更新日期：2018-01-01 00:00:00

abstract：:MicroRNAs (miRNAs) exhibit a crucial role in the regulation of angiogenesis and tumor progression, of which miR-199a-5p (miR-199a) has been reported to function as a tumor suppressor in multiple malignancies. However, the precise mechanisms underlying miR-199a in hemangiomas (HAs) remain elusive. In this study, we fou...

journal_title：International journal of immunopathology and pharmacology

authors： Wang Y,Dai YX,Wang SQ,Qiu MK,Quan ZW,Liu YB,Ou JM

更新日期：2018-01-01 00:00:00

abstract：:We examined the expression of human leukocyte antigen (HLA) and composition of differentiated T cells in the peripheral blood to understand the characteristics of the immune changes in patients with adult-onset Still's disease (AOSD). This study enrolled patients with AOSD (n = 14), patients with rheumatoid arthritis ...

journal_title：International journal of immunopathology and pharmacology

authors： Jung JY,Choi B,Sayeed HM,Suh CH,Kim YW,Kim HA,Sohn S

更新日期：2018-01-01 00:00:00

abstract：:Oxymatrine (OMT) as a type of alkaloids collected from Sophora flavescens Ait exerts some biological functions including anticancer properties. Here, we investigated the therapeutic effects of OMT in gastric cancer cells (HGC 27 and AGS). As a result, the exposure of gastric cancer (GC) cells to OMT contributed to the...

journal_title：International journal of immunopathology and pharmacology

authors： Huang Y,Zhang J,Wang G,Chen X,Zhang R,Liu H,Zhu J

更新日期：2018-01-01 00:00:00

abstract：:HSP60 has been implicated in chronic inflammatory disease pathogenesis, including chronic obstructive pulmonary disease (COPD), but the mechanisms by which this chaperonin would act are poorly understood. A number of studies suggest a role for extracellular HSP60, since it can be secreted from cells and bind Toll-like...

journal_title：International journal of immunopathology and pharmacology

authors： Sangiorgi C,Vallese D,Gnemmi I,Bucchieri F,Balbi B,Brun P,Leone A,Giordano A,Conway de Macario E,Macario AJ,Cappello F,Di Stefano A

更新日期：2017-12-01 00:00:00

abstract：:This study aimed to explore the role and mechanism(s) of flunarizine hydrochloride in the intracerebral hemorrhage (ICH) rats. The 32 adult male Sprague Dawley (SD) rats were randomly assigned into four groups: control group, sham group, ICH group, and FLU + ICH group. The effects of flunarizine hydrochloride were ass...

journal_title：International journal of immunopathology and pharmacology

authors： Niu J,Hu R

更新日期：2017-12-01 00:00:00

abstract：:Finding new strategies to counteract periprosthetic infection and implant failure is a main target in orthopedics. Staphylococcus aureus, the leading etiologic agent of orthopedic implant infections, is able to enter and kill osteoblasts, to stimulate pro-inflammatory chemokine secretion, to recruit osteoclasts, and t...

journal_title：International journal of immunopathology and pharmacology

authors： Selan L,Papa R,Ermocida A,Cellini A,Ettorre E,Vrenna G,Campoccia D,Montanaro L,Arciola CR,Artini M

更新日期：2017-12-01 00:00:00

abstract：:Mast cells are vital mediators of drug allergy and, therefore, studying the relationship between drug allergy and mast cells is essential. Sinomenine is the principal active component of Sinomenium acutum, which has anti-inflammatory and anti-immune effects, and is used to treat various rheumatoid diseases. However, al...

journal_title：International journal of immunopathology and pharmacology

authors： Wang N,Liu R,Liu Y,Zhang R,He L

更新日期：2016-12-01 00:00:00

abstract：:We reported a case of an 11-year-old girl admitted to our hospital for goiter, tachycardia, sweating, and visible and palpable thyroid. Thyroid function tests revealed a low thyrotropin level (<0.004 mIU/L) and elevated free thyroxine level (3.4 ng/ dL) diagnosed with Graves' disease and treated with methimazole. This...

journal_title：International journal of immunopathology and pharmacology

authors： Arrigo T,Cutroneo PM,Vaccaro M,Impollonia D,Squadrito V,Mecchio A,Salpietro C,Altavilla D

更新日期：2016-12-01 00:00:00

abstract：:Deficits in glucose, impaired insulin signalling and brain insulin resistance are common in the pathogenesis of Alzheimer's disease (AD); therefore, some scholars even called AD type 3 diabetes mellitus. Curcumin can reduce the amyloid pathology in AD. Moreover, it is a well-known fact that curcumin has anti-oxidant a...

journal_title：International journal of immunopathology and pharmacology

authors： Feng HL,Dang HZ,Fan H,Chen XP,Rao YX,Ren Y,Yang JD,Shi J,Wang PW,Tian JZ

更新日期：2016-12-01 00:00:00

abstract：:The role of profilin as an allergen has long been questioned. The capacity of profilin to induce respiratory symptoms has recently been demonstrated; moreover, over 50% of patients sensitized to profilin experienced symptoms after the ingestion of plant-derived foods, suggesting that profilin should be considered as a...

journal_title：International journal of immunopathology and pharmacology

authors： Nucera E,Aruanno A,Rizzi A,Pecora V,Patriarca G,Buonomo A,Mezzacappa S,Schiavino D

更新日期：2016-09-01 00:00:00

abstract：:Acrodermatitis enteropathic (AE) is a rare autosomal recessive disorder due to a zinc deficiency and characterized by a classical triad of symptoms: dermatitis, alopecia, and diarrhea. The defective gene is SLC39A4, which encodes a zinc transporter. Nevertheless many abnormalities in SLC39A4 have been relieved, only 5...

journal_title：International journal of immunopathology and pharmacology

authors： Ricci G,Ferrari S,Calamelli E,Ricci L,Neri I,Patrizi A

更新日期：2016-06-01 00:00:00

abstract：:The aim of this study was to investigate the possible protective effects of diallyl trisulfide (DATS) against naphthalene-induced oxidative and inflammatory damage in the livers and lungs of mice. Elevated serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels showed significant hepatic damag...

journal_title：International journal of immunopathology and pharmacology

authors： Zhang F,Zhang Y,Wang K,Liu G,Yang M,Zhao Z,Li S,Cai J,Cao J

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Inflammation, which is a hallmark of asthma, is one of the main sources of oxidative stress in the human body. Thiols are powerful antioxidants that protect cells against the consequences of oxidative stress. We aimed to investigate whether asthma and montelukast monotherapy affect the total plasma thiol poo...

journal_title：International journal of immunopathology and pharmacology

authors： Dilek F,Ozkaya E,Kocyigit A,Yazici M,Guler EM,Dundaroz MR

更新日期：2016-03-01 00:00:00

abstract：:Salmonellosis-induced diarrhea, is one of the commonest cause of childhood mortality in developing countries. Using of probiotics is viewed as a promising means for reducing the pathogenic loads of bacterial infection. The current study aimed to evaluate the potential antimicrobial and immunomodulatory efficacy of iso...

journal_title：International journal of immunopathology and pharmacology

authors： Mazaya B,Hamzawy MA,Khalil MA,Tawkol WM,Sabit H

更新日期：2015-12-01 00:00:00

abstract：:Small B-cell lymphocytic lymphoma/chronic lymphocytic leukemia, which typically affects elderly people, is a group of conditions that are not clinically uniform. It has been suggested that using the combined activity of the monoclonal antibody anti-CD20 (rituximab) and Listeria monocytogenes toxin listeriolysin O (LLO...

journal_title：International journal of immunopathology and pharmacology

authors： Gryzik M,Grzywocz Z,Wasilewska D,Kawiak J,Stachowiak R,Bielecki J,Hoser G

更新日期：2015-09-01 00:00:00

abstract：:Chemokines and their receptors have been implicated in cell migration and metastasis of multiple malignant tumors. But the function of CXCR6 signaling in gastric cancer is not comprehensively understood. In the present study, we hypothesized that CXCR6 signaling might play an essential role in the progression of gastr...

journal_title：International journal of immunopathology and pharmacology

authors： Li Y,Fu LX,Zhu WL,Shi H,Chen LJ,Ye B

更新日期：2015-06-01 00:00:00

abstract：:Non-cystic fibrosis bronchiectasis (nCFb) is an acquired condition of variable etiology. An impaired mucociliary clearance seems to be one of the mechanisms behind nCFb, and treatment involves antibiotics, mucoactive agents, and airway clearance techniques (ACTs). Traditional ACTs have four components: postural draina...

journal_title：International journal of immunopathology and pharmacology

authors： Snijders D,Fernandez Dominguez B,Calgaro S,Bertozzi I,Escribano Montaner A,Perilongo G,Barbato A

更新日期：2015-06-01 00:00:00

abstract：:Since the beginning of the 21st century, carbon-based nanomaterials (CNTs) have been introduced in pharmacy and medicine for drug delivery system in therapeutics. CNTs have proved able to transport a wide range of molecules across membranes and into living cells; therefore, they have attracted great interest in biomed...

journal_title：International journal of immunopathology and pharmacology

authors： Lamberti M,Pedata P,Sannolo N,Porto S,De Rosa A,Caraglia M

更新日期：2015-03-01 00:00:00

abstract：:The aim of this study was to evaluate the concentrations of CD45pos leukocytes in the semen samples of infertile patients with low testicular volume (TV) compared to subjects with normal TV. The testis was considered normal in size when it had a volume between 15 and 25 cm(3), low-normal with a volume between 10 and 1...

journal_title：International journal of immunopathology and pharmacology

authors： La Vignera S,Condorelli RA,Morgia G,Favilla V,Russo GI,Cimino S,Vicari E,Calogero AE

更新日期：2015-03-01 00:00:00

abstract：:Acosta YY, Montes-Casado M, Aragoneses L et al. (2014) Suppression of CD4(+) T lymphocyte activation "in vitro" and experimental encephalomyelitis "in vivo" by the phosphatidyl inositol 3-kinase inhibitor PIK-75. International Journal of Immunopathology and Pharmacology 27(1): 53-67. In the Acknowledgements section of...

journal_title：International journal of immunopathology and pharmacology

authors：

更新日期：2015-03-01 00:00:00

abstract：:Classification of upper tract urothelial preneoplastic and neoplastic lesions mirrors that of the urinary bladder, with all lesions of the bladder urothelium being possible in the upper tract and vice versa. There are three major groups of non-invasive urothelial neoplasms: flat, papillary, and inverted. These three g...

journal_title：International journal of immunopathology and pharmacology

authors： Mazzucchelli R,Scarpelli M,Galosi AB,Di Primio R,Lopez-Beltran A,Cheng L,Montironi R

更新日期：2014-10-01 00:00:00

abstract：:Although Sho-seiryu-to (SST), used as a traditional herbal (Kampo) medicine mainly in China and Korea, is shown to have immunomodulating potential, such as an anti-allergic one, its underlying mechanism has not been completely clarified. To partially address the issue, we explored its effects on allergen-exposed monon...

journal_title：International journal of immunopathology and pharmacology

authors： Tanaka M,Inoue K,Kitamura Y,Shimada A,Takano H

更新日期：2014-10-01 00:00:00

abstract：:Betamethasone is an anti-inflammatory steroid drug used in cases of anaphylactic and allergic reactions, of Alzheimer and Addison diseases and in soft tissue injuries. It modulates gene expression for anti-inflammatory activity suppressing the immune system response. This latter effect might decrease the effectiveness...

journal_title：International journal of immunopathology and pharmacology

authors： Artini M,Papa R,Cellini A,Tilotta M,Barbato G,Koverech A,Selan L

更新日期：2014-10-01 00:00:00

abstract：:The possible use of cell therapies for neurological lesions and disorders is regarded as a very promising strategy. However, many issues related to cell type, tissue donor, expected biological action etc., are still open. In this study human mesenchymal stem cells derived from different fetal and adult tissues were ex...

journal_title：International journal of immunopathology and pharmacology

authors： Paradisi M,Alviano F,Pirondi S,Lanzoni G,Fernandez M,Lizzo G,Giardino L,Giuliani A,Costa R,Marchionni C,Bonsi L,Calza L

更新日期：2014-07-01 00:00:00

abstract：:Extranodal non-Hodgkin lymphomas limited to the larynx are rare, accounting for less than 1% of all laryngeal neoplasms. The most common site of development of primary laryngeal lymphomas is the supraglottic region. In most cases, the presenting symptoms are hoarseness, dysphagia, dyspnea, and cervical lymphadenopathy...

journal_title：International journal of immunopathology and pharmacology

authors： Zapparoli M,Trolese AR,Remo A,Sina S,Bonetti A,Micheletto C

更新日期：2014-07-01 00:00:00