Human mesenchymal stem cells produce bioactive neurotrophic factors: source, individual variability and differentiation issues.

abstract：:Paraneoplastic sensitive neuropathy is one of the most common presentations among a group of cancer-related disorders known as Paraneoplastic Neurological Syndromes (PNS). PNS likely have an autoimmune etiology since they have been associated with the presence of antibodies against neuronal antigens expressed by tumor...

journal_title：International journal of immunopathology and pharmacology

authors： Nappi L,Formisano L,Damiano V,Matano E,Bianco R,Tortora G

更新日期：2010-10-01 00:00:00

abstract：:Since the beginning of the 21st century, carbon-based nanomaterials (CNTs) have been introduced in pharmacy and medicine for drug delivery system in therapeutics. CNTs have proved able to transport a wide range of molecules across membranes and into living cells; therefore, they have attracted great interest in biomed...

journal_title：International journal of immunopathology and pharmacology

authors： Lamberti M,Pedata P,Sannolo N,Porto S,De Rosa A,Caraglia M

更新日期：2015-03-01 00:00:00

abstract：:Hematide is a synthetic PEGylated peptidic erythropoiesis stimulating agent (ESA) that is presently being developed for the correction of anemia in patients with chronic renal failure. Unlike currently marketed ESAs, Hematide does not possess any sequence homology to erythropoietin (EPO) and has not elicited moribund ...

journal_title：International journal of immunopathology and pharmacology

authors： Woodburn KW,Schatz PJ,Fong KL,Beaumier P

更新日期：2010-01-01 00:00:00

abstract：:An association between human immunodeficiency virus type I (HIV-1) protease inhibitors (PIs) and galactorrhoea/hyperprolactinemia adverse effect has recently been reported in four HIV-1-infected women treated with PIs (indinavir, nelfinavir, ritonavir or saquinavir). This could be explained by a direct effect of riton...

journal_title：International journal of immunopathology and pharmacology

authors： Orlando G,Brunetti L,Vacca M

更新日期：2002-01-01 00:00:00

abstract：:Solid tumors such as head and neck squamous cell carcinoma (HNSCC) display an intense interaction between tumoral factors and the immune system. Functional modulation of tumor-infiltrating and peripheral blood immune cells plays an important role during tumor progression. In this pilot study we compared biological fun...

journal_title：International journal of immunopathology and pharmacology

authors： Trellakis S,Farjah H,Bruderek K,Dumitru CA,Hoffmann TK,Lang S,Brandau S

更新日期：2011-07-01 00:00:00

abstract：:Ionizing irradiation causes damage and functional failure of irradiation-sensitive systems and tissues such as small intestine. The molecular mechanisms underlying inflammatory and adaptive responses to acute irradiation damage are poorly understood. Using a mouse model of total-body γ-irradiation, we assessed the irr...

journal_title：International journal of immunopathology and pharmacology

authors： Gorbunov NV,Garrison BR,Kiang JG

更新日期：2010-10-01 00:00:00

abstract：:The treatment with infliximab is employed successfully in Crohn's disease (CD) but predictors of efficacy are lacking. Activation of the transcription factor NF-kB has been demonstrated in CD and its inhibition is one of the mechanisms by which anti-inflammatory agents exert their effects. We evaluated the production ...

journal_title：International journal of immunopathology and pharmacology

authors： Guidi L,Costanzo M,Ciarniello M,De Vitis I,Pioli C,Gatta L,Pace L,Tricerri A,Bartoloni C,Coppola L,Balistreri P,Doria G,Fedeli G,Gasbarrini GB

更新日期：2005-01-01 00:00:00

abstract：:It is well known that in some conditions bacteria of physiological flora of gastrointestinal tract may become pathogenic. Each complaint which causes injury of gastrointestinal wall integrity permits bacteria to penetrate the tissues and affect the tissue cells. Since mast cells represent one of very important and num...

journal_title：International journal of immunopathology and pharmacology

authors： Brzezińska-Blaszczyk E,Olejnik AK

更新日期：1999-01-01 00:00:00

abstract：:This study aimed to explore the role and mechanism(s) of flunarizine hydrochloride in the intracerebral hemorrhage (ICH) rats. The 32 adult male Sprague Dawley (SD) rats were randomly assigned into four groups: control group, sham group, ICH group, and FLU + ICH group. The effects of flunarizine hydrochloride were ass...

journal_title：International journal of immunopathology and pharmacology

authors： Niu J,Hu R

更新日期：2017-12-01 00:00:00

abstract：:Salmonellosis-induced diarrhea, is one of the commonest cause of childhood mortality in developing countries. Using of probiotics is viewed as a promising means for reducing the pathogenic loads of bacterial infection. The current study aimed to evaluate the potential antimicrobial and immunomodulatory efficacy of iso...

journal_title：International journal of immunopathology and pharmacology

authors： Mazaya B,Hamzawy MA,Khalil MA,Tawkol WM,Sabit H

更新日期：2015-12-01 00:00:00

abstract：:To assess the rate of sexual distress, sexual dysfunction and relationship quality and their association with clinical variables in women with systemic sclerosis (SSc), 102 sexually active women with SSc were recruited. Sexual distress, sexual dysfunction and dissatisfaction with relationship quality were investigated...

journal_title：International journal of immunopathology and pharmacology

authors： Rosato E,Rossi C,Molinaro I,Di Giulio MA,Trombetta AC,Marra AM,Gigante A,Barbano B,Quarta S,Pisarri S,Afeltra A,Salsano F

更新日期：2014-04-01 00:00:00

abstract：:Isoprostanes are prostaglandin isomers produced from the peroxidation of polyunsaturated fatty acids from the cellular membrane. They have been used as a specific index of cellular lipoperoxidation and as an indirect measure of oxidative stress. However, these molecules also present several biological activities. An o...

journal_title：International journal of immunopathology and pharmacology

authors： Belli R,Amerio P,Brunetti L,Orlando G,Toto P,Proietto G,Vacca M,Tulli A

更新日期：2005-07-01 00:00:00

abstract：:About three decades ago, the primary mechanism of action of the non-steroidal anti-inflammatory drugs (NSAIDs) was elucidated when their inhibitory action on the production of prostaglandins was discovered. It was found that their action is centred on the inhibition of the cyclooxygenase (COX) enzyme responsible for c...

journal_title：International journal of immunopathology and pharmacology

authors： van der Bijl P,van der Bijl P Jr

更新日期：2003-05-01 00:00:00

abstract：:In a preliminary study a reduction in natural killer (NK) cell activity in peripheral blood lymphocytes (PBL) was observed in a group of workers exposed to levels of extremely low frequency-magnetic fields (ELF-MF) exceeding 1 microT. This study was performed to confirm the results. In 121 workers engaged in various o...

journal_title：International journal of immunopathology and pharmacology

authors： Gobba F,Bargellini A,Bravo G,Scaringi M,Cauteruccio L,Borella P

更新日期：2009-10-01 00:00:00

abstract：:To investigate the in vivo role of caspase-3 in Terminal Transferase metabolism DMSO-treated RPMI-8402, a human pre-T cell line was used. In DMSO treated samples (3)H-dGTP incorporation and TdT phosphorylation occurs after 4 hours of treatment. After 8 hours cells undergo TdT proteolysis in addition to its inactivatio...

journal_title：International journal of immunopathology and pharmacology

authors： Trubiani O,Guarnieri S,Paganelli R,Di Primio R

更新日期：2002-09-01 00:00:00

abstract：:Infections caused by the nematode Trichinella spiralis (T. spiralis) are characterized by an inflammatory response in the host. The aim of this study was to identify and evaluate markers for monitoring mice infected with T. spiralis and treated with or without mimosine. The markers that have been used were total and d...

journal_title：International journal of immunopathology and pharmacology

authors： Hitoglou S,Frydas S,Hatzistilianou M,Pappa S,Gougoustamou D,Kotsis A

更新日期：2004-05-01 00:00:00

abstract：:The aim of this report is to present a new investigative approach to implant dentistry based on the correlation of qualitative and quantitative data reported on the same figure by overlapping different images collected on the specimen with different investigative systems. Six unloaded titanium dental implants retrieve...

journal_title：International journal of immunopathology and pharmacology

authors： Traini T,Degidi M,Murmura G,Piattelli A,Caputi S

更新日期：2007-01-01 00:00:00

abstract：:After birth various bacterial species, mainly streptococci, colonize the oral cavity and are frequently isolated from carious lesions in children. Previous studies suggest that an earlier colonization of a child's mouth by cariogenic organisms might be related to a higher risk of caries. The aim of this study is to as...

journal_title：International journal of immunopathology and pharmacology

authors： Duse M,Zicari AM,Berlutti F,Ernesti I,Occasi F,Leonardi L,Polimeni A

更新日期：2014-01-01 00:00:00

abstract：:Cryopyrin-associated periodic syndromes are categorized as a spectrum of three autoinflammatory diseases, namely familial cold auto-inflammatory syndrome, Muckle-Wells syndrome and chronic infantile neurological cutaneous articular syndrome. All are caused by mutations in the NLRP3 gene coding for cryopyrin and result...

journal_title：International journal of immunopathology and pharmacology

authors： Cantarini L,Lucherini OM,Frediani B,Brizi MG,Bartolomei B,Cimaz R,Galeazzi M,Rigante D

更新日期：2011-10-01 00:00:00

abstract：:Cyclic AMP phosphodiesterase (cAMP PDE) seems to be important in pulp tissues. High levels of cAMP PDE have been demonstrated to be in dental pulp cells. In the present study cAMP PDE activity was analyzed in normal healthy human dental pulps, in reversible pulpitis and in irreversible pulpitis. Enzymatic cAMP PDE con...

journal_title：International journal of immunopathology and pharmacology

authors： Spoto G,Menna V,Serra E,Santoleri F,Perfetti G,Ciavarelli L,Trentini P

更新日期：2004-09-01 00:00:00

abstract：:Calligonum polygonoides is locally called as Phog which belongs to the Polygonaceae family. It is traditionally used as an antifungal. The methanolic extract, hexane extract, ethyl acetate extract and aqueous extract were screened against Candida albicans and Aspergillus niger in seven concentrations, that is, 1.8, 2....

journal_title：International journal of immunopathology and pharmacology

authors： Ahmad S,Akram M

更新日期：2019-01-01 00:00:00

abstract：:Asthma is a chronic airway inflammatory disease associated with airway hyperresponsiveness which affects subjects with genetic predisposition. An association has been reported between some polymorphisms in various cytokine genes and asthma. Most of them are single nucleotide polymorphisms (SNPs). These polymorphisms a...

journal_title：International journal of immunopathology and pharmacology

authors： Ricciardolo FL,Sorbello V,Silvestri M,Giacomelli M,Debenedetti VM,Malerba M,Ciprandi G,Rossi GA,Rossi A,Bontempelli M

更新日期：2013-01-01 00:00:00

abstract：UNLABELLED:Insulin-like growth factor-1 (IGF-1) is involved in regulating the Th-1/Th-2 balance, favoring the development of the Th-2 compartment which enhances fibrosis, one of the main characteristics of Chronic Lung Disease (CLD) in premature newborns. Limited data is available concerning a possible association betw...

journal_title：International journal of immunopathology and pharmacology

authors： Capoluongo E,Vento G,Ameglio F,Lulli P,Matassa PG,Carrozza C,Santini SA,Antenucci M,Castagnola M,Giardina B,Romagnoli C,Zuppi C

更新日期：2006-01-01 00:00:00

abstract：:There is much evidence to show the efficacy of adalimumab, a human monoclonal antibody targeting tumour necrosis factor-alpha, in the treatment of plaque psoriasis. In this open-label experience, 147 high-need patients suffering from plaque psoriasis, with a mean Psoriasis Area and Severity Index (PASI) of 18.8, and c...

journal_title：International journal of immunopathology and pharmacology

authors： Vena GA,Galluccio A,De Simone C,Mastrandrea V,Buquicchio R,La Greca S,Dattola S,Puglisi Guerra A,Donato L,Cantoresi F,De Pità O,Pezza M,D Agostino M,Vernaci R,Miracapillo A,Valenti G,Cassano N

更新日期：2009-01-01 00:00:00

abstract：:Polysensitization is a feature of allergic rhinitis (AR) that significantly impairs the quality of life (QoL) of AR patients. Allergen-specific immunotherapy is the only causal therapy for AR. However, the polysensitization phenomenon may represent a crucial obstacle as far as it concerns the choice of the allergen ex...

journal_title：International journal of immunopathology and pharmacology

authors： Ciprandi G,Incorvaia C,Puccinelli P,Scurati S,Masieri S,Frati F

更新日期：2010-04-01 00:00:00

abstract：:Non-cystic fibrosis bronchiectasis (nCFb) is an acquired condition of variable etiology. An impaired mucociliary clearance seems to be one of the mechanisms behind nCFb, and treatment involves antibiotics, mucoactive agents, and airway clearance techniques (ACTs). Traditional ACTs have four components: postural draina...

journal_title：International journal of immunopathology and pharmacology

authors： Snijders D,Fernandez Dominguez B,Calgaro S,Bertozzi I,Escribano Montaner A,Perilongo G,Barbato A

更新日期：2015-06-01 00:00:00

abstract：:The use of particles from micro to nanoscale provides benefits to diverse scientific fields, but because a large percentage of their atoms lie on the surface, nanomaterials could be highly reactive and pose potential risks to humans. Due to their wide range of application, Cobalt nano-particles are of great interest b...

journal_title：International journal of immunopathology and pharmacology

authors： Petrarca C,Perrone A,Verna N,Verginelli F,Ponti J,Sabbioni E,Di Giampaolo L,Dadorante V,Schiavone C,Boscolo P,Mariani Costantini R,Di Gioacchino M

更新日期：2006-10-01 00:00:00

abstract：:The expression of Ikaros family transcription factors and consequently their signalling pathway is limiting for hematopoietic and lymphocyte development in mice and human. Due to their importance, these transcription factors are highly homologous between species. As an initial approach to examining the possible involv...

journal_title：International journal of immunopathology and pharmacology

authors： Paradzik M,Novak S,Mokrovic G,Bordukalo Niksic T,Heckel D,Stipic J,Pavicic Baldani D,Cicin-Sain L,Antica M

更新日期：2012-10-01 00:00:00

abstract：:Allergic drug reactions can be classified as immediate, accelerated or delayed. This classification usually correlates with the mechanism involved: immediate reactions are IgE mediated and delayed reactions are T cell dependent. We analyzed lymphocyte involvement in patients with these reactions by determining cell su...

journal_title：International journal of immunopathology and pharmacology

authors： Torres MJ,Mayorga C,Fernández TD,Cornejo-García JA,Antúnez C,Valenzuela M,Del Prado MF,Rodriguez-Pena R,Blanca M

更新日期：2006-01-01 00:00:00

abstract：:A decrease in cholesterol blood level, not due to a decrease synthesis by the liver, has been observed in patients suffering from tumors. In this work cholesterol blood was evaluated in patients affected by monoclonal gammopathy who were not subjected to any treatment. The blood of 25 patients were analyzed for protei...

journal_title：International journal of immunopathology and pharmacology

authors： Pugliese L,Bernardini I,Viola-Magni MP,Albi E

更新日期：2006-04-01 00:00:00