abstract：OBJECTIVE:We investigated the effectiveness of rituximab (an anti-CD20 monoclonal antibody) in patients with eosinophilic granulomatosis with polyangiitis (EGPA). METHODS:We performed a systematic literature review from the inception dates until July 20, 2020 for articles reporting rituximab administration to treat EG...

journal_title：Autoimmunity reviews

authors： Akiyama M,Kaneko Y,Takeuchi T

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:The gold standard for secondary thromboprophylaxis in APS is long term anticoagulation with vitamin K antagonists (VKAs). Because of their widespread use and potential advantages of directs oral anticoagulants (DOACs) over VKAs, they have been prescribed in APS without definitive evidence of their safety and...

journal_title：Autoimmunity reviews

authors： Dufrost V,Wahl D,Zuily S

更新日期：2021-01-01 00:00:00

abstract：:As part of a landmark review of the antigen excess, Jacobs et al. (Autoimmunity Reviews 2015;14:160-167) contrast how immunoassay "interference" by non-target biomolecules can cause spurious readings for clinical diagnostic tests. The purpose of the present Letter is to complement and analytically extend this descript...

journal_title：Autoimmunity reviews

authors： Holmes TH

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Anti-neutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV) is a rare multi-system autoimmune disease, characterised by a pauci-immune necrotising small-vessel vasculitis, with a relapsing and remitting course. Like many autoimmune diseases, the exact aetiology of AAV, and the factors that influenc...

journal_title：Autoimmunity reviews

authors： Scott J,Hartnett J,Mockler D,Little MA

更新日期：2020-11-01 00:00:00

abstract：:"Rhupus" or "rhupus syndrome" is a poorly described and underdiagnosed disease in which features of both rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) appear in the same patient, most often sequentially. The SLE-related involvement is usually mild, dominated by hematological abnormalities and skin, ...

journal_title：Autoimmunity reviews

authors： Antonini L,Le Mauff B,Marcelli C,Aouba A,de Boysson H

更新日期：2020-09-01 00:00:00

abstract：INTRODUCTION:Immune checkpoint inhibitors (ICIs) are associated with immune-related adverse events (irAEs). Among them, ICIs-induced systemic sclerosis (SSc) is poorly known. METHODS:To better characterize this irAE, our comprehensive approach combined the description of ICIs-induced scleroderma cases, the systematic ...

journal_title：Autoimmunity reviews

authors： Terrier B,Humbert S,Preta LH,Delage L,Razanamahery J,Laurent-Roussel S,Mestiri R,Beaudeau L,Legendre P,Goupil F,Hadjadj J,Stolzenberg MC,Treluyer JM,Westeel V,Valnet-Rabier MB,Wislez M,Mouthon L,Chouchana L

更新日期：2020-08-01 00:00:00

abstract：:The severe form of COVID-19 share several clinical and laboratory features with four entities gathered under the term "hyperferritinemic syndromes" and including macrophage activation syndrome (MAS), adult-onset Still's disease (AOSD), catastrophic anti-phospholipid syndrome (CAPS) and septic shock. COVID-19 systemic ...

journal_title：Autoimmunity reviews

authors： Colafrancesco S,Alessandri C,Conti F,Priori R

更新日期：2020-07-01 00:00:00

abstract：:Rheumatoid arthritis is a well-known chronic inflammatory joint disorder. It encompasses systemic inflammation, autoimmunity and development of several joint abnormalities leading to the lifelong disability and increased mortality. Exosomes are nano-sized (30-100 nm) mammalian extracellular particles with essential pr...

journal_title：Autoimmunity reviews

authors： Tavasolian F,Moghaddam AS,Rohani F,Abdollahi E,Janzamin E,Momtazi-Borojeni AA,Moallem SA,Jamialahmadi T,Sahebkar A

更新日期：2020-06-01 00:00:00

abstract：:A few scores predicting the short-term risk of mortality in Systemic sclerosis (SSc) have been reported to date. Our study aimed to create a predictive 15-year all-cause mortality score at the time of the diagnosis of SSc. The study was based on the Spanish Scleroderma Registry (RESCLE). The cohort was split up in der...

journal_title：Autoimmunity reviews

authors： Rubio-Rivas M,Corbella X,Guillén-Del-Castillo A,Tolosa Vilella C,Colunga Argüelles D,Argibay A,Vargas Hitos JA,Todolí Parra JA,González-Echávarri C,Ortego-Centeno N,Trapiella Martínez L,Rodríguez Carballeira M,Marín Ballvé A,Pl

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Immunoglobulin A vasculitis (IgAV) is a systemic small vessel vasculitis for which treatment of severe cases is usually based on glucocorticoids and other conventional immunosuppressive drugs. The role of rituximab for resistant or refractory cases has been explored in isolated case reports and small series....

journal_title：Autoimmunity reviews

authors： Hernández-Rodríguez J,Carbonell C,Mirón-Canelo JA,Diez-Ruiz S,Marcos M,Chamorro AJ

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVE:Renal involvement in anti-neutrophil cytoplasm antibody (ANCA)-associated vasculitis is associated with significant morbidity and higher mortality rates. This study examined clinical manifestations associated with renal involvement in ANCA-associated vasculitis within a large, international cross-sectional co...

journal_title：Autoimmunity reviews

authors： Kronbichler A,Shin JI,Lee KH,Nakagomi D,Quintana LF,Busch M,Craven A,Luqmani RA,Merkel PA,Mayer G,Jayne DRW,Watts RA

更新日期：2020-04-01 00:00:00

abstract：INTRODUCTION:Spondyloarthrits (SpA) share clinical, genetic and immunological features with Inflammatory Bowel Diseases (IBD), and enteropathic SpA (eSpA) represent the clinical evidence of the association between gut and joint diseases. This cross-sectional study aimed to report data of eSpA patients collected from th...

journal_title：Autoimmunity reviews

authors： Picchianti-Diamanti A,Lorenzetti R,Chimenti MS,Luchetti MM,Conigliaro P,Canofari C,Benfaremo D,Bruzzese V,Laganà B,Perricone R,SIGR.

更新日期：2020-02-01 00:00:00

abstract：:The pathophysiology of autoimmune diseases such as Multiple Sclerosis (MS) involves a complex interaction between genetic and environmental factors. Studies of monozygotic twins suggest a significant role for environmental factors in susceptibility to MS. Numerous studies, driven by the "Hygiene Hypothesis," have focu...

journal_title：Autoimmunity reviews

authors： Wasko NJ,Nichols F,Clark RB

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:According to criteria for the classification of Systemic Lupus Erythematosus (SLE), thrombocytopenia is one of the disease-defining hematologic disorders. Since the recognition of Antiphospholipid Syndrome (APS), thrombocytopenia was frequently reported but several studies yielded contradictory results on th...

journal_title：Autoimmunity reviews

authors： Chock YP,Moulinet T,Dufrost V,Erkan D,Wahl D,Zuily S

更新日期：2019-11-01 00:00:00

abstract：:Patients with rheumatoid arthritis (RA) suffer cardiovascular events 1.5-2 fold than the general population, and cardiovascular (CV) events are leading cause of death in patients with RA. It is known that patients with RA have endothelial dysfunction, related with impaired function of endothelial progenitor cells (EPC...

journal_title：Autoimmunity reviews

authors： Blum A,Adawi M

更新日期：2019-07-01 00:00:00

abstract：:Recurrent pericarditis is a frequent and troublesome complication of acute pericarditis. Aspirin or non-steroidal anti-inflammatory drugs (NSAIDs) and colchicine are the mainstay of therapy but few data is available on second-line treatment. We retrospectively analyzed 13 patients, 7 females (54%), median age 40 years...

journal_title：Autoimmunity reviews

authors： Peiffer-Smadja N,Domont F,Saadoun D,Cacoub P

更新日期：2019-06-01 00:00:00

abstract：:To date, no immunomodulatory drug has proved efficacious in primary Sjögren's syndrome (pSS). In pSS, difficulties in drug efficacy assessment is related to the large spectrum of clinical involvements (glandular/extraglandular involvement), to the lack of correlation between symptoms of dryness and glandular function ...

journal_title：Autoimmunity reviews

authors： Felten R,Scher F,Sibilia J,Gottenberg JE,Arnaud L

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:To analyse the ocular manifestations of patients with GPA, their treatment and outcome. METHODS:Retrospective cohort study performed at the National Referral Center for Vasculitis, Cochin Hospital, Paris (France), from January 2005 to December 2015. Among 308 patients with a new diagnosis of GPA in accordanc...

journal_title：Autoimmunity reviews

authors： Pérez-Jacoiste Asín MA,Charles P,Rothschild PR,Terrier B,Brézin A,Mouthon L,Guillevin L,Puéchal X

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Anticardiolipin antibodies of the immunoglobulin G isotype (IgG aCL) have been suggested as risk factor for arterial and venous thrombosis. No conclusive data in patients with coronary artery disease (CAD) do exist. We investigate the risk of recurrent CAD according to the presence of IgG aCL. METHODS:We pe...

journal_title：Autoimmunity reviews

authors： Pastori D,Bucci T,Triggiani M,Ames PRJ,Parrotto S,Violi F,Pignatelli P,Farcomeni A

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVES:To assess the efficacy and safety of Rituximab (RTX) in adult primary central nervous system vasculitis (PCNSV). METHODS:We retrospectively assessed the effect of RTX in 6 patients with PCNSV. Five of the 6 were refractory to high dose glucocorticoids (GCs) and/or conventional immunosuppressants (IS). The s...

journal_title：Autoimmunity reviews

authors： Salvarani C,Brown RD Jr,Muratore F,Christianson TJH,Galli E,Pipitone N,Cassone G,Huston J III,Giannini C,Warrington K,Hunder GG

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Myositis is a heterogeneous group of muscular auto-immune diseases with clinical and pathological criteria that allow the classification of patients into different sub-groups. Inclusion body myositis is the most frequent myositis above fifty years of age. Diagnosing inclusion body myositis requires expertise...

journal_title：Autoimmunity reviews

authors： Dzangué-Tchoupou G,Mariampillai K,Bolko L,Amelin D,Mauhin W,Corneau A,Blanc C,Allenbach Y,Benveniste O

更新日期：2019-04-01 00:00:00

abstract：:Complex regional pain syndrome (CRPS) has been considered to be an autoimmune disease and there have been clinical trials with intravenous immunoglobulin. Often the etiology of the so-called CRPS diagnosis cannot be discerned and there are no validated instruments that provide functional metrics. The term complex regi...

journal_title：Autoimmunity reviews

authors： Chang C,McDonnell P,Gershwin ME

更新日期：2019-03-01 00:00:00

abstract：INTRODUCTION:The upcoming of biosimilars in rheumatic diseases have generated considerable interest throughout the past five years among pharmaceutical industries and regulatory agencies, their development is associated with considerable variation and heterogeneity on the variable requirements for license and marketing...

journal_title：Autoimmunity reviews

authors： Scheinberg M,Azevedo V

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:The objectives of this systematic review and meta-regression were: 1) to compare the prevalence of cervical HPV infection between SLE patients and healthy controls and 2) to evaluate the relationship between cervical HPV infection and traditional and SLE-related risk factors for cervical HPV infection in thes...

journal_title：Autoimmunity reviews

authors： García-Carrasco M,Mendoza-Pinto C,Rojas-Villarraga A,Molano-González N,Vallejo-Ruiz V,Munguía-Realpozo P,Colombo AL,Cervera R

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Adrenal insufficiency (AI) is associated with high morbidity and mortality. The aim of this systematic review was to enhance diagnostic approaches and summarize therapeutic strategies in the management of AI in patients with systematic lupus erythematosus (SLE) or antiphospholipid syndrome (APS). METHODS:A ...

journal_title：Autoimmunity reviews

authors： Lee KH,Lee H,Lee CH,Kim JY,Kim JM,Kim SS,Jeong S,Hwang IS,Kim N,Kim NE,Shin S,Shin D,Song JS,Shin DH,Kim JD,Kim J,Lee YS,Kang H,Kim DH,Moon SH,Rho WS,Lee JY,Kronbichler A,Shin JI

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Increased expression of RNA polymerase 1 (POL1) molecular pathway was reported to be associated with increased disease activity in patients with multiple sclerosis (MS). However, the operating molecular mechanisms that characterize the pattern of acute MS relapse activity has not been thoroughly studied. OB...

journal_title：Autoimmunity reviews

authors： Achiron A,Zilkha-Falb R,Feldman A,Bovim M,Rozen O,Sarova-Pinhas I,Magalashvili D,Dolev M,Menascu S,Gurevich M

更新日期：2018-12-01 00:00:00

abstract：:The impact of dietary interventions such as specific types of diet or nutritional supplements in rheumatoid arthritis (RA) has been subject to increased attention in recent years. The recognition of the unmet need to better understand the effects of specific dietary interventions on disease outcomes in RA, along with ...

journal_title：Autoimmunity reviews

authors： Petersson S,Philippou E,Rodomar C,Nikiphorou E

更新日期：2018-11-01 00:00:00

abstract：:The classical autoimmunity paradigm in rheumatoid arthritis (RA) is strongly supported by immunogenetics suggesting follicular helper T-cell responses driving high titre specific autoantibodies that pre-dates disease onset. Using the immunological disease continuum model of inflammation against self with "pure" adapti...

journal_title：Autoimmunity reviews

authors： McGonagle D,Watad A,Savic S

更新日期：2018-11-01 00:00:00

abstract：:Rheumatoid Arthritis (RA) is a complex systemic autoimmune disease in which various cell types are involved. Among them, neutrophils have been recognized as important players in the onset and the progression of RA. The pathogenic role of neutrophils in RA lies in the alteration of several processes, including increase...

journal_title：Autoimmunity reviews

authors： Cecchi I,Arias de la Rosa I,Menegatti E,Roccatello D,Collantes-Estevez E,Lopez-Pedrera C,Barbarroja N

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:To investigate differences between childhood (cPAN)- and adult-onset polyarteritis nodosa (aPAN) patients. METHODS:cPAN patients' clinical findings at onset and outcomes were compared to those of aPAN patients from the French Vasculitis Study Group registry matched for year of enrollment and initial systemic...

journal_title：Autoimmunity reviews

authors： Iudici M,Quartier P,Pagnoux C,Merlin E,Agard C,Aouba A,Roblot P,Cohen P,Terrier B,Mouthon L,Guillevin L,Puéchal X,French Vasculitis Study Group.

更新日期：2018-10-01 00:00:00

abstract：:Stress is defined as the pscyophysiological reaction in which the steady state is disturbed or threatened. Stress is not always perceived as a negative response. Stress results when environmental demands exceed an individuals' adaptive capacities. Autoimmune diseases are heterogeneous group of chronic diseases which o...

journal_title：Autoimmunity reviews

authors： Sharif K,Watad A,Coplan L,Lichtbroun B,Krosser A,Lichtbroun M,Bragazzi NL,Amital H,Afek A,Shoenfeld Y

更新日期：2018-10-01 00:00:00

abstract：:Scleroderma renal crisis (SRC) is an uncommon but still life-threatening manifestation of systemic sclerosis (SSc). The incidence of SRC has decreased in the last few decades, probably due to a widespread use of vasodilators in SSc patients. It is well-recognized that exposure to different drugs can trigger SRC (corti...

journal_title：Autoimmunity reviews

authors： Zanatta E,Polito P,Favaro M,Larosa M,Marson P,Cozzi F,Doria A

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVES:A reliable tool to evaluate flow is paramount in systemic sclerosis (SSc). We describe herein on the one hand a systematic literature review on the reliability of laser speckle contrast analysis (LASCA) to measure the peripheral blood perfusion (PBP) in SSc and perform an additional pilot study, investigatin...

journal_title：Autoimmunity reviews

authors： Cutolo M,Vanhaecke A,Ruaro B,Deschepper E,Ickinger C,Melsens K,Piette Y,Trombetta AC,De Keyser F,Smith V,EULAR Study Group on Microcirculation in Rheumatic Diseases.

更新日期：2018-08-01 00:00:00

abstract：:Antimalarials have been an effective and safe treatment for autoimmune rheumatic diseases such as systemic lupus erythematosus for more than a hundred years. There are surprisingly few reports of hydroxychloroquine use in the systemic vasculitides. Hydroxychloroquine has antithrombotic, cardiovascular, antimicrobial a...

journal_title：Autoimmunity reviews

authors： Casian A,Sangle SR,D'Cruz DP

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVE:To describe safety and efficacy of rituximab in patients with systemic sclerosis. METHODS:We included 13 patients with systemic sclerosis treated with rituximab and pooled with 40 additional patients from the literature. SSc rituximab untreated patients were matched to rituximab treated ones. RESULTS:Thirte...

journal_title：Autoimmunity reviews

authors： Thiebaut M,Launay D,Rivière S,Mahévas T,Bellakhal S,Hachulla E,Fain O,Mekinian A

更新日期：2018-06-01 00:00:00

abstract：:Autoimmune Syndrome Induced by Adjuvant (ASIA) is a definition aimed to describe the common etiological process at the root of five clinical entities sharing similar symptomatology: macrophagic myofasciitis syndrome (MMF), Gulf War Syndrome (GWS), sick building syndrome (SBS), siliconosis, and post vaccination autoimm...

journal_title：Autoimmunity reviews

authors： Segal Y,Dahan S,Sharif K,Bragazzi NL,Watad A,Amital H

更新日期：2018-05-01 00:00:00

abstract：:Inflammatory arthritides are chronic diseases characterised by an increase in cardiovascular risk, largely attributable to the synergy between high-grade systemic inflammation and an elevated prevalence of traditional cardiovascular risk factors. Amongst the latter, insulin resistance and type 2 diabetes (T2D) play a ...

journal_title：Autoimmunity reviews

authors： Ursini F,Russo E,Ruscitti P,Giacomelli R,De Sarro G

更新日期：2018-04-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) and juvenile SLE (jSLE) are autoimmune disorders naturally associated with several genetic, environmental, hormonal, and immunological contributing factors. It has been assumed that vitamin D deficiency may have a role in the immune activation of patients with SLE and play an active ...

journal_title：Autoimmunity reviews

authors： Stagi S,Rigante D

更新日期：2018-03-01 00:00:00

abstract：:The concept of undifferentiated spondyloarthritis has been introduced recently to describe a clinical setting where the classical features of spondyloarthritis (SpA) are not fully present. Whether this is a discrete entity was the basis of a debate during the 4th International Congress on Controversies in Rheumatology...

journal_title：Autoimmunity reviews

authors： Deodhar A,Miossec P,Baraliakos X

更新日期：2018-01-01 00:00:00

abstract：:Over the past 20years, much has been written about the potential role of vitamin D in on adverse health outcomes. In recent years, evidence has accumulated regarding the effect of vitamin D on the immune system, and its different cells. Some studies have noted lower vitamin D concentrations in patients with SLE. These...

journal_title：Autoimmunity reviews

authors： Shoenfeld Y,Giacomelli R,Azrielant S,Berardicurti O,Reynolds JA,Bruce IN

更新日期：2018-01-01 00:00:00