abstract：:Spontaneous nontraumatic intracerebral hemorrhage is associated with high morbidity and mortality. Given the risk of rapid neurological deterioration, early identification with rapid neuroimaging is vital. Predictors of outcome, such as spot sign and intracerebral hemorrhage score, can help guide management goals. Man...

journal_title：Cardiology in review

authors： Kurian C,Kaur K,Kaur G,Sahni R

更新日期：2021-01-01 00:00:00

abstract：:Inflammatory cardiomyopathy is a broad term encompassing any disease leading to myocardial inflammation with associated cardiac dysfunction. While endomyocardial biopsy remains the gold standard for diagnosis, non-invasive imaging techniques, such as cardiac magnetic resonance imaging and positron emission tomography,...

journal_title：Cardiology in review

authors： Li B,Lento PA,Pan S

更新日期：2020-11-02 00:00:00

abstract：:Severe acute respiratory coronavirus-2 (SARS-CoV-2) is responsible for one of the greatest public health challenges of our lifetime, the coronavirus disease 2019 (COVID-19) pandemic. Because of the complicated postinfection sequelae and grave consequences, the search for effective therapies has become a worldwide prio...

journal_title：Cardiology in review

authors： Mehta M,Shyh GI

更新日期：2020-11-01 00:00:00

abstract：:Arsenic is a ubiquitously dispersed metalloid that has been implicated as the cause of various adverse health effects. Human exposure to arsenic primarily occurs through contaminated drinking water and dietary intake of rice and grains, posing a great public health risk to millions of people worldwide. High levels of ...

journal_title：Cardiology in review

authors： Kononenko M,Frishman WH

更新日期：2020-09-15 00:00:00

abstract：:Intensive glycemic control significantly increases the risk of hypoglycemia in patients with diabetes mellitus. Recent data have shown that hypoglycemia may also be a marker of cardiovascular disease in these patients. We performed a systemic review and a meta-analysis to evaluate the relationship between severe hypog...

journal_title：Cardiology in review

authors： Malik AH,Yandrapalli S,Aronow WS,Jain D,Frishman WH,Panza JA,Cooper HA

更新日期：2020-09-01 00:00:00

abstract：:Atherosclerosis develops and rapidly progresses in saphenous veins grafts after coronary bypass surgery. In contrast to native coronary artery, percutaneous revascularization does not impede the progression of saphenous vein atherosclerosis and saphenous vein graft failure commonly ensues. The protracted patency of ar...

journal_title：Cardiology in review

authors： Motwani A,Ayinapudi K,Singh T,Maini R,Hendel R,Le Jemtel TH

更新日期：2020-09-01 00:00:00

abstract：:The human intestine contains the largest and most diverse ecosystem of microbes. The main function of the intestinal bacterial flora is to limit the growth of potentially pathogenic microorganisms. However, the intestinal microbiota is increasingly emerging as a risk factor for the development of cardiovascular diseas...

journal_title：Cardiology in review

authors： Anselmi G,Gagliardi L,Egidi G,Leone S,Gasbarrini A,Miggiano GAD,Galiuto L

更新日期：2020-06-18 00:00:00

abstract：:Left ventricular noncompaction cardiomyopathy is a heart disease with relevant potential complications including heart failure, life-threatening arrhythmias, and embolic events. In order to prevent adverse outcomes, it is crucial to appropriately recognize and manage this cardiomyopathy. In this paper, we report the m...

journal_title：Cardiology in review

authors： Di Fusco SA,Lucà F,Madeo A,Massimiliano Rao C,Iorio A,Rizzo M,Dalila Luisella Delcre S,Colivicchi F,Gabrielli D,Paolo Pino G,Massimo Gulizia M

更新日期：2020-05-01 00:00:00

abstract：:An estimated 400,000 coronary artery bypass graft operations are performed annually in the United States. Saphenous vein grafts are the most commonly used conduits; however, graft failure is common. In contrast, left internal mammary artery grafts have more favorable long-term patency rates. Guidelines recommend aggre...

journal_title：Cardiology in review

authors： Collins D,Goldberg S

更新日期：2020-01-01 00:00:00

abstract：:The field of durable left ventricular assist devices has advanced dramatically since its introduction into the clinical realm. From the first-generation pulsatile HeartMate XVE device to the second-generation continuous axial flow HeartMate-2 to the current third-generation centrifugal flow devices, the left ventricul...

journal_title：Cardiology in review

authors： Levine A,Gass A

更新日期：2019-11-01 00:00:00

abstract：:Cholesterol metabolism and transport has been a major focus in cardiovascular disease risk modification over the past several decades. Hydroxymethylglutaryl-CoA reductase inhibitors (statins) have been the most commonly used agents, with the greatest benefit in reducing both the primary and secondary risks of cardiova...

journal_title：Cardiology in review

authors： Grabie M,Tai CH,Frishman WH

更新日期：2019-09-01 00:00:00

abstract：:Computed tomography is an established tool in the assessment of cardiac anatomy and function. As demonstrated by single photon emission computed tomography, positron emission tomography, and magnetic resonance, the noninvasive evaluation of coronary hemodynamics is an important step in guiding clinical management. Nev...

journal_title：Cardiology in review

authors： Lempel M,Frishman WH

更新日期：2019-07-01 00:00:00

abstract：:In this article, we critically evaluate the evidence relating to the effects of the Mediterranean diet (MD) on the risk of cardiovascular disease (CVD). Strong evidence indicating that the MD prevents CVD has come from prospective cohort studies. However, there is only weak supporting evidence from randomized controll...

journal_title：Cardiology in review

authors： Temple NJ,Guercio V,Tavani A

更新日期：2019-05-01 00:00:00

abstract：:Myocardial infarction (MI) complicated by cardiogenic shock (MI-CS) is a major cause of cardiovascular morbidity and mortality. Predictors of outcomes in MI-CS include clinical, laboratory, radiologic variables, and management strategies. This article reviews the existing literature on short- and long-term predictors ...

journal_title：Cardiology in review

authors： Acharya D

更新日期：2018-09-01 00:00:00

abstract：:As direct oral anticoagulants (DOACs) have demonstrated favorable efficacy and safety outcomes compared with vitamin K antagonists for the treatment and prevention of venous thromboembolism and the prevention of stroke and systemic embolism in patients with nonvalvular atrial fibrillation, their role in the management...

journal_title：Cardiology in review

authors： Finks SW,Dobesh PP,Trujillo TC,Crossley GH

更新日期：2018-09-01 00:00:00

abstract：:Two-dimensional speckle tracking echocardiography represents a novel, simple, and reproducible technique for the estimation of left ventricular myocardial deformation (strain) and the evaluation of left ventricular twist mechanics. During the last few years, its clinical and prognostic implications in cardiomyopathies...

journal_title：Cardiology in review

authors： Zegkos T,Parcharidou D,Ntelios D,Efthimiadis G,Karvounis H

更新日期：2018-05-01 00:00:00

abstract：:Hypertrophic cardiomyopathy (HCM) is a heart disease characterized by hypertrophy of the left ventricular myocardium and is most often caused by mutations in sarcomere genes. The structural and functional abnormalities are not explained by flow-limiting coronary artery disease or loading conditions. The disease affect...

journal_title：Cardiology in review

authors： Adamczak DM,Oko-Sarnowska Z

更新日期：2018-05-01 00:00:00

abstract：:Automated validated devices should be used for measuring blood pressure (BP). A systolic BP between 120 and 129 mm Hg with a diastolic BP < 80 mm Hg should be treated by lifestyle measures. Lifestyle measures plus BP lowering drugs should be used for secondary prevention of recurrent cardiovascular disease (CVD) event...

journal_title：Cardiology in review

authors： Aronow WS,Frishman WH

更新日期：2018-03-01 00:00:00

abstract：:Numerous investigators have attempted to target the natriuretic peptide system in the treatment of heart failure since it was first described over 30 years ago. The history of neprilysin inhibition as a treatment for heart failure has been characterized by numerous setbacks. Recently, the PARADIGM-HF trial has shown f...

journal_title：Cardiology in review

authors： Bartell N,Frishman WH

更新日期：2017-11-01 00:00:00

abstract：:Evacetrapib is a cholesteryl ester transfer protein (CETP) inhibitor that has been recently studied as a cholesterol modifying agent to reduce cardiovascular risk and mortality in high risk cardiovascular disease patients. Evacetrapib acts to decrease lipid exchange through CETP inhibition. CETP acts to transfer chole...

journal_title：Cardiology in review

authors： Eyvazian VA,Frishman WH

更新日期：2017-03-01 00:00:00

abstract：:Cardiac resynchronization therapy (CRT) has become a mainstay therapy to improve clinical outcomes of patients with left ventricular systolic dysfunction and a wide QRS complex, in addition to guideline-directed medical therapy. As clinical experience with CRT continues to expand, the device and lead design, along wit...

journal_title：Cardiology in review

authors： Ng CY,Heist EK

更新日期：2017-01-01 00:00:00

abstract：:Heart failure continues to be a leading cause of morbidity and mortality throughout the United States. The pathophysiology of heart failure involves the activation of complex neurohormonal pathways, many of which mediate not only hypertrophy and fibrosis within ventricular myocardium and interstitium, but also activat...

journal_title：Cardiology in review

authors： Carazo M,Berger JS,Reyentovich A,Katz SD

更新日期：2016-09-01 00:00:00

abstract：:Loop diuretics are central to the management of fluid overload in acute decompensated heart failure. However, a variance in the response to loop diuretics can alter a patient's clinical course and has an adverse effect on clinical outcomes. Thus, a diminished response to loop diuretics is an important clinical issue. ...

journal_title：Cardiology in review

authors： Bowman BN,Nawarskas JJ,Anderson JR

更新日期：2016-09-01 00:00:00

abstract：:Cryptogenic stroke (CS) accounts for 20% to 40% of ischemic strokes. CS is defined as a cortical infarct suggestive of an embolic stroke with no identifiable cardiac etiology, large vessel occlusive disease, or small vessel lacunar stroke. The likely etiologies for CS are patent foramen ovale (PFO) and paroxysmal atri...

journal_title：Cardiology in review

authors： Marks SJ,Khera S

更新日期：2016-07-01 00:00:00

abstract：:Short QT syndrome is a rare inherited autosomal dominant cardiac channelopathy associated with malignant ventricular and atrial arrhythmias. A shortened corrected QT interval is a marker for risk of malignant arrhythmias, which are secondary to increased transmural dispersion of repolarization. The underlying gain of ...

journal_title：Cardiology in review

authors： Khera S,Jacobson JT

更新日期：2016-07-01 00:00:00

abstract：:Epigenetic regulatory mechanisms play key roles in cardiac development, differentiation, homeostasis, response to stress and injury, and disease. Human heart failure (HF) epigenetic regulatory mechanisms have not been deciphered to date. This 2-part review distills the rapidly evolving research focused on human HF epi...

journal_title：Cardiology in review

authors： DiSalvo TG

更新日期：2015-11-01 00:00:00

abstract：:Antiplatelet therapy reduces the risks for cardiovascular morbidity and mortality in patients with atherosclerotic disease, and it is also beneficial in managing peripheral arterial disease (PAD). These agents work through various therapeutic pathways to achieve antithrombotic effects. Although single- or two-drug reg...

journal_title：Cardiology in review

authors： Lam S,Tran T

更新日期：2015-09-01 00:00:00

abstract：:Evidence-based management of heart failure (HF) with preserved left ventricular ejection fraction (LVEF; HFpEF) remains a major gap in the care of patients with HF. Clinical trials directed toward the population with HFpEF have been disappointing, although renin-angiotensin-aldosterone system blockade appears to preve...

journal_title：Cardiology in review

authors： Jumean MF,Konstam MA

更新日期：2015-07-01 00:00:00

abstract：:Left ventricular (LV) remodeling is the most common term used to describe the functional, structural, myocellular, and interstitial changes that occur in response to myocardial injury and/or chronic changes in myocardial loading conditions. Progression of LV remodeling over time in response to neurohormonal activation...

journal_title：Cardiology in review

authors： Saraon T,Katz SD

更新日期：2015-07-01 00:00:00

abstract：:Mitral regurgitation (MR) is the most common cardiac valvular disease in the United States. Approximately 4 million people have severe MR and roughly 250,000 new diagnoses of MR are made each year. Mitral valve surgery is the only treatment that prevents progression of heart failure and provides sustained symptomatic ...

journal_title：Cardiology in review

authors： Doshi JV,Agrawal S,Garg J,Paudel R,Palaniswamy C,Doshi TV,Gotsis W,Frishman WH

更新日期：2014-11-01 00:00:00

abstract：:Established coronary artery disease has a prevalence of 7% in adult Americans, accounting for 16 million people. As morbidity and mortality rates have risen, research efforts to identify the pathophysiologic mechanisms of systolic dysfunction have risen in parallel. The current goal is to develop new therapeutic strat...

journal_title：Cardiology in review

authors： Romero J,Lupercio F,Haramati LB,Garcia MJ,Lucariello RJ

更新日期：2014-09-01 00:00:00

abstract：:Sudden death (SD) is the most dramatic event in hypertrophic cardiomyopathy (HCM), often representing the first clinical manifestation of the disease, and the first concern of the clinicians who take care of such patients. HCM is now recognized as the primary cause of SD in young persons (<35 years of age), including ...

journal_title：Cardiology in review

authors： Efthimiadis GK,Zegkos T,Meditskou S,Hadjimiltiades S

更新日期：2014-09-01 00:00:00

abstract：:Interleukin 1β (IL-1β) is a proinflammatory cytokine that has been implicated in a number of rheumatologic and inflammatory conditions. The production and secretion of IL-1β from inflammatory cells is a tightly regulated process that has been extensively described and studied. In recent years, IL-1β has been associate...

journal_title：Cardiology in review

authors： McCarty S,Frishman W

更新日期：2014-07-01 00:00:00

abstract：:Magnesium, the fourth most abundant cation in the human body, is involved in several essential physiological, biochemical, and cellular processes regulating cardiovascular function. It plays a critical role in modulating vascular smooth muscle tone, endothelial cell function, and myocardial excitability and is thus ce...

journal_title：Cardiology in review

authors： Kolte D,Vijayaraghavan K,Khera S,Sica DA,Frishman WH

更新日期：2014-07-01 00:00:00

abstract：:Cardiovascular magnetic resonance using late gadolinium enhancement (LGE) provides a unique opportunity to assess myocardial tissue in vivo. LGE enables tissue characterization in ischemic and nonischemic cardiomyopathies and other cardiac diseases. LGE is associated with adverse clinical outcomes across a range of di...

journal_title：Cardiology in review

authors： Panovsky R,Pleva M,Feitova V,Kruzliak P,Meluzin J,Kincl V

更新日期：2014-05-01 00:00:00

abstract：:It has been shown in rodents and newborn babies that brown adipose tissue (BAT) plays an important role in the generation of heat for maintenance of core body temperature. BAT is responsible for the process of adaptive thermogenesis, which involves heat generation in response to a drop in the environment's temperature...

journal_title：Cardiology in review

authors： Mund RA,Frishman WH

更新日期：2013-11-01 00:00:00

abstract：:About 50 years ago, Norman Jefferis Holter invented a device that opened the possibility of recording heart activity over long periods of time. This invention, together with the rapid developments in electronics, has enabled a revolutionary change in the diagnosis and management of cardiac diseases. Ambulatory cardiac...

journal_title：Cardiology in review

authors： Romero I

更新日期：2013-09-01 00:00:00

abstract：:The presence of pulmonary arterial hypertension (PAH) in pregnancy is rare and signifies a high-risk pregnancy. Although the majority of mothers have knowledge of their condition before pregnancy, approximately one-third of patients are diagnosed during pregnancy. Termination of pregnancy should be discussed, and is o...

journal_title：Cardiology in review

authors： Martínez MV,Rutherford JD

更新日期：2013-07-01 00:00:00

abstract：:Atrial fibrillation (AF) is an independent risk factor for ischemic stroke occurrence, severity, recurrence, and mortality. Anticoagulation therapy for the prevention of thromboembolism is critical in patients with AF who are at risk of stroke. Warfarin has been an efficacious anticoagulant for this purpose, but its u...

journal_title：Cardiology in review

authors： Lam S

更新日期：2013-07-01 00:00:00

abstract：:Saphenous vein graft (SVG) disease after coronary artery bypass grafting (CABG) occurs in three phases: thrombosis, intimal hyperplasia, and atherosclerosis. Within the first month, thrombosis plays a major role. From month 1 to month 12, intimal hyperplasia occurs. Beyond 12 months, atherosclerosis becomes the primar...

journal_title：Cardiology in review

authors： Kim FY,Marhefka G,Ruggiero NJ,Adams S,Whellan DJ

更新日期：2013-03-01 00:00:00