The prognostic impact of myocardial late gadolinium enhancement.

Abstract:

:Cardiovascular magnetic resonance using late gadolinium enhancement (LGE) provides a unique opportunity to assess myocardial tissue in vivo. LGE enables tissue characterization in ischemic and nonischemic cardiomyopathies and other cardiac diseases. LGE is associated with adverse clinical outcomes across a range of different cardiac conditions and may improve risk stratification for death, sudden cardiac death, or serious adverse events beyond traditional prognostic markers. Generally, matching data for the prognostic impact of LGE are frequently reached in cardiac disorders. In other diseases, only a limited number of trials are available, but it is anticipated that the prognostic impact of delayed enhancement will become evident. The development and validation of new cardiovascular magnetic resonance methods for diffuse myocardial fibrosis measurements would even improve the prognostic impact of LGE. The evaluation of diffuse myocardial fibrosis has a great potential in large-scale diseases, including their initial phases, with the possibility to identify patients at risk for subsequent development of clinical heart failure, to assess repeatedly the stage and progression of cardiac diseases, and to monitor the effect of treatment.

journal_name

Cardiol Rev

journal_title

Cardiology in review

authors

Panovsky R,Pleva M,Feitova V,Kruzliak P,Meluzin J,Kincl V

doi

10.1097/CRD.0000000000000002

subject

Has Abstract

pub_date

2014-05-01 00:00:00

pages

128-39

issue

3

eissn

1061-5377

issn

1538-4683

pii

00045415-201405000-00003

journal_volume

22

pub_type

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