Short QT Syndrome in Current Clinical Practice.

Abstract:

:Short QT syndrome is a rare inherited autosomal dominant cardiac channelopathy associated with malignant ventricular and atrial arrhythmias. A shortened corrected QT interval is a marker for risk of malignant arrhythmias, which are secondary to increased transmural dispersion of repolarization. The underlying gain of function mutations in the potassium channels are most common but genetic testing remains low yield. This review discusses the cellular mechanisms, genetic involvement, clinical presentation, and current recommended management of patients with short QT syndrome relevant to current clinical practice.

journal_name

Cardiol Rev

journal_title

Cardiology in review

authors

Khera S,Jacobson JT

doi

10.1097/CRD.0000000000000091

subject

Has Abstract

pub_date

2016-07-01 00:00:00

pages

190-3

issue

4

eissn

1061-5377

issn

1538-4683

journal_volume

24

pub_type

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