Sudden Cardiac Death in Hypertrophic Cardiomyopathy.

Abstract:

:Hypertrophic cardiomyopathy (HCM) is a heart disease characterized by hypertrophy of the left ventricular myocardium and is most often caused by mutations in sarcomere genes. The structural and functional abnormalities are not explained by flow-limiting coronary artery disease or loading conditions. The disease affects at least 0.2% of the population worldwide and is the most common cause of sudden cardiac death in young people and competitive athletes because of fatal ventricular arrhythmia. In some patients, however, HCM has a benign course. Therefore, it is of utmost importance to properly evaluate patients and single out those who would benefit from an implanted cardioverter defibrillator. In this article, we review and summarize the sudden cardiac death risk stratification algorithms, methods of preventing death due to HCM, and novel factors that may improve the existing prediction models.

journal_name

Cardiol Rev

journal_title

Cardiology in review

authors

Adamczak DM,Oko-Sarnowska Z

doi

10.1097/CRD.0000000000000184

subject

Has Abstract

pub_date

2018-05-01 00:00:00

pages

145-151

issue

3

eissn

1061-5377

issn

1538-4683

pii

00045415-201805000-00005

journal_volume

26

pub_type

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