听力与言语-语言病理学

行为科学

医学伦理学

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  • Prevalence of AT1R antibody (AT1R-Ab) among Malaysian multi-ethnic population.

    abstract:BACKGROUND:Angiotensin II type 1 receptor antibody (AT1R-Ab) is a non-HLA antibody that has been reported to cause antibody-mediated rejection and graft loss in kidney transplantation. The prevalence of positive AT1R-Ab varies between 8% and 18% in different regions. Thus, this study aims to determine the prevalence of...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2020.07.005

    authors: Jalalonmuhali M,Caroll R,Deayton S,Emery T,Humphreys I,Lim SJ,Lim SK,Coates T

    更新日期:2020-12-01 00:00:00

  • CD28 gene polymorphisms and acute cellular rejection after liver transplantation.

    abstract::The co-stimulatory molecule CD28 plays an important role in T-cell-mediated immune response like acute cellular liver transplant rejection. The aim of the retrospective case- control study was to examine whether the single nucleotide polymorphisms (SNPs) rs3116487, rs3116494, and rs3116496 of the CD28 gene are associa...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2020.10.002

    authors: Thude H,Tiede P,Sterneck M,Peine S,Nashan B,Koch M

    更新日期:2020-12-01 00:00:00

  • Genetic diversity of HLA system in two populations from Yucatán, Mexico: Mérida and rural Yucatán.

    abstract::We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 324 Mexicans from the state of Yucatán living in the city of Mérida (N = 192) and rural communities (N = 132), to obtain information regarding allelic and haplotypic frequencies. We found that the most frequent haploty...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2019.07.280

    authors: Lara-Riegos J,Barquera R,Castillo-Chávez OD,Medina-Escobedo CE,Hernández-Zaragoza DI,Arrieta-Bolaños E,Clayton S,Ponnandai-Shanmugavel KS,Bravo-Acevedo A,Zúñiga J,Yunis EJ,Bekker-Méndez C,Granados J

    更新日期:2020-09-01 00:00:00

  • Genetic diversity of HLA system in two populations from Tabasco, Mexico: Villahermosa and rural Tabasco.

    abstract::We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 224 Mexicans from the state of Tabasco living in the city of Villahermosa (N = 82) and rural communities (N = 142), to obtain information regarding allelic and haplotypic frequencies. We found that the most frequent ha...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2019.07.286

    authors: Solís-Martínez R,Barquera R,Ponnandai-Shanmugavel KS,Vega-Martínez MDR,Vázquez-Castillo TV,Arrieta-Bolaños E,Clayton S,Hernández-Zaragoza DI,Bravo-Acevedo A,Immel A,Salgado-Galicia N,Zúñiga J,Yunis EJ,Bekker-Méndez C,Granados

    更新日期:2020-09-01 00:00:00

  • Genetic diversity of HLA system in a population from Guerrero, Mexico.

    abstract::We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 144 Mexicans from the state of Guerrero to obtain information regarding allelic and haplotypic frequencies. We find that the ten most frequent haplotypes in the state of Guerrero include eight Native American and two E...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2019.05.015

    authors: Juárez-Nicolás F,Barquera R,Martínez-Álvarez JC,Hernández-Zaragoza DI,Ortega-Yáñez A,Arrieta-Bolaños E,Clayton S,Bravo-Acevedo A,Arrazola-García MA,Immel A,Juárez-Barreto V,Benítez-Arvizu G,Vega-Martínez MDR,García-Álvarez R,

    更新日期:2020-09-01 00:00:00

  • Genetic diversity of HLA system in four populations from Baja California, Mexico: Mexicali, La Paz, Tijuana and rural Baja California.

    abstract::We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 250 Mexicans from the states of Baja California Norte and Baja California Sur living in Mexicali (N = 100), La Paz (N = 75), Tijuana (N = 25) and rural communities (N = 50) to obtain information regarding allelic and h...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2019.06.007

    authors: Escobedo-Ruíz A,Barquera R,González-Martín A,Argüelles-San Millán JM,Uribe-Duarte MG,Hernández-Zaragoza DI,Clayton S,Arrieta-Bolaños E,Ruíz-Corral MJ,Goné-Vázquez I,Arellano-Prado FP,Martínez-Álvarez JC,García-Arias VE,Rodrígue

    更新日期:2020-09-01 00:00:00

  • Genetic diversity of HLA system in six populations from Mexico City Metropolitan Area, Mexico: Mexico City North, Mexico City South, Mexico City East, Mexico City West, Mexico City Center and rural Mexico City.

    abstract::We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 1217 Mexicans from the Mexico City Metropolitan Area living in the northern (N = 751), southern (N = 52), eastern (N = 79), western (N = 33), and central (N = 152) Mexico City, and rural communities (N = 150), to obtai...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2019.07.297

    authors: Barquera R,Martínez-Álvarez JC,Hernández-Zaragoza DI,Bravo-Acevedo A,Juárez-Nicolás F,Arriaga-Perea AJ,Vega-Martínez MDR,Ortega-Yáñez A,Benítez-Arvizu G,Arrieta-Bolaños E,Clayton S,Juárez-Cortés ED,López-Gil C,García-Álvarez R

    更新日期:2020-09-01 00:00:00

  • T follicular helper cell-mediated IL-21 production suppresses FOXP3 expression of T follicular regulatory-like cells in diffuse large B cell lymphoma patients.

    abstract::Based on CD25 expression, T follicular helper cells (Tfh) could be divided into T follicular regulatory (Tfr)-like subset (CD25+CD4+CXCR5+) and CD25- Tfh subset (CD25-CD4+CXCR5+). Patients with diffuse large B cell lymphoma (DLBCL) display high level of Tfr-like cells in blood and tumor. This Tfr-like subset could sup...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2020.05.008

    authors: Ma X,Zha J,He J,Chen L,Huang J,Wu W,Tian P,Qian BH,Yu L,Jiang Y,Xu B

    更新日期:2020-08-01 00:00:00

  • CD1 gene polymorphism and susceptibility to celiac disease: Association of CD1E*02/02 in Moroccans.

    abstract::CD1 glycoproteins are a class of antigen presenting molecules that bind and present non-peptidic antigens (lipids and glycolipids) for immune recognition. CD1 polymorphisms, although limited, could have a critical role in antimicrobial, anticancer, and autoimmune responses and disease susceptibility. Ethnic difference...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2020.05.005

    authors: Aureli A,Aboulaghras S,Oumhani K,Del Beato T,Sebastiani P,Colanardi A,El Aouad R,Ben El Barhdadi I,Piancatelli D

    更新日期:2020-07-01 00:00:00

  • HLA study in Bolivian Quechua Amerindians from Titikaka Lake Area.

    abstract::Quechua Amerindians established Inca Empire and chose Cuzco as their capital. Their language is closely related to that of Aymara ethnic group and both of them were originated from Titikaka Lake Altiplano area. In the present study we have analyzed Bolivian Quechua HLA profile and found that it has common characters w...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2020.05.002

    authors: Arnaiz-Villena A,Juarez I,Lopez-Nares A,Crespo-Yuste E,Callado A,Suarez-Trujillo F

    更新日期:2020-07-01 00:00:00

  • Cytometry-based analysis of HLA-G functions according to ILT2 expression.

    abstract::HLA-G was described as a molecule inhibiting NK and T cells functions through its receptor, ILT2. However, most functional studies of HLA-G were so far performed on heterogeneous immune populations and regardless of ILT2 expression. This may lead to an underestimation of the effect of HLA-G. Thus, considering the immu...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2020.02.001

    authors: Jacquier A,Dumont C,Carosella ED,Rouas-Freiss N,LeMaoult J

    更新日期:2020-04-01 00:00:00

  • A role for both HLA-F and HLA-G in reproduction and during pregnancy?

    abstract::The human major histocompatibility complex includes a group of non-classical HLA class I genes, HLA-E, -F and -G. While nearly all focus since the discovery of these class Ib molecules have been on basic biochemistry and molecular biology of HLA-G and HLA-E, as well as their expression patterns, functions in immune mo...

    journal_title:Human immunology

    pub_type: 杂志文章,评审

    doi:10.1016/j.humimm.2019.09.006

    authors: Persson G,Jørgensen N,Nilsson LL,Andersen LHJ,Hviid TVF

    更新日期:2020-04-01 00:00:00

  • High-resolution allele frequencies for NGS based HLA-A, B, C, DQB1 and DRB1 typing of 23,595 bone marrow donors recruited for the Polish central potential unrelated bone marrow donor registry.

    abstract::Next-generation sequencing (NGS)-based typings of HLA-A, B, C, DQB1 and DRB1 loci were performed from 2018 to 2019 in 23 595 newly recruited or re-typed adult potential bone marrow donors registered in Poltransplant Registry to characterize allele and haplotype frequencies of HLA system for loci important for hematopo...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2019.12.005

    authors: Nestorowicz K,Bogacz A,Bukowska A,Chraplak M,Czerwiński J,Góralski M,Gronkowski M,Jopek K,Kniżewski Ł,Kolasiński M,Kowalski ML,Nowak J,Sowiński M,Wróblewska-Kabba S,Tymoniuk B,Dudkiewicz M

    更新日期:2020-01-01 00:00:00

  • A blueprint for electronic utilization of ambiguous molecular HLA typing data in organ allocation systems and virtual crossmatch.

    abstract::Virtual crossmatch (VXM) compares a transplant candidate's unacceptable antigens to the HLA typing of the donor before an organ offer is accepted and, in selected cases, supplant a prospective physical crossmatch. However, deceased donor typing can be ambiguous, leading to uncertainty in compatibility prediction. We h...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2020.01.007

    authors: Kaur N,Pinelli D,Kransdorf EP,Pando MJ,Smith G,Murphey CL,Kamoun M,Bray RA,Tambur A,Gragert L

    更新日期:2020-01-01 00:00:00

  • Siglec-10 expression is up-regulated in activated human CD4+ T cells.

    abstract::Most sialic acid-binding immunoglobulin-like lectins (Siglecs) suppress immune cell function but are expressed at low levels on human T cells. We found that soluble CD52 inhibited T cell signalling by ligating Siglec-10, but the presence of Siglec-10 on human T cells has been questioned. To address this concern, we ex...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2020.01.009

    authors: Bandala-Sanchez E,Bediaga NG,Naselli G,Neale AM,Harrison LC

    更新日期:2020-01-01 00:00:00

  • Impaired circulating CD56dim NK cells are associated with decompensation of HBV-related cirrhosis.

    abstract::NK cells play an important role in immune regulation and defense of infection, but their characteristics in patients with decompensated cirrhosis and their relationship with liver function remain unclear. We studied the functional properties of NK cells (including CD56dim NK and CD56bright NK cells) in patients with H...

    journal_title:Human immunology

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.humimm.2019.11.006

    authors: Jiang Y,Chen Y,Chen L,Yao W,Guan J,Liu X,Wei X,Lin X

    更新日期:2020-01-01 00:00:00

  • Immune phenotype predicts new onset diabetes after kidney transplantation.

    abstract::Few data are available concerning immune factors involved in the occurrence of new onset diabetes after transplantation (NODAT). Our objective was to determine an immune profile associated with the subsequent development of NODAT. The secondary objective was to build a predictive model of NODAT. We studied a prospecti...

    journal_title:Human immunology

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.humimm.2019.08.006

    authors: Ducloux D,Courivaud C,Bamoulid J,Crepin T,Gaiffe E,Laheurte C,Vauchy C,Rebibou JM,Saas P,Borot S

    更新日期:2019-11-01 00:00:00

  • Effect of MUC1 length polymorphisms on the NLRP3 inflammasome response of human macrophages.

    abstract::Mucin 1 is a cell-membrane associated mucin, expressed on epithelial and immune cells that helps protect against pathogenic infections. In humans, MUC1 is highly polymorphic, predominantly due to the presence of a variable number tandem repeat (VNTR) region in the extracellular domain that results in MUC1 molecules of...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2019.06.001

    authors: Dhar P,Sarkar S,Ng GZ,Kalitsis P,Saeed MA,McGuckin MA,Ellis JA,Sutton P

    更新日期:2019-10-01 00:00:00

  • The impact of non-HLA antibodies on outcomes after lung transplantation and implications for therapeutic approaches.

    abstract::The role of donor-specific antibodies (DSA) to mismatched human leukocyte antigens (HLA) in lung allograft rejection has been recognized over the past 20 years. During this time, there has been growing experience and recognition of an important role for non-HLA antibodies in lung allograft rejection. Multiple self-ant...

    journal_title:Human immunology

    pub_type: 杂志文章,评审

    doi:10.1016/j.humimm.2019.04.008

    authors: Hachem RR

    更新日期:2019-08-01 00:00:00

  • The ABCs (DRDQDPs) of the prozone effect in single antigen bead HLA antibody testing: Lessons from our highly sensitized patients.

    abstract::Accurate identification of HLA antibodies using the single antigen bead (SAB) assay is critical for assessment of pre/post-transplant immunological risk and successful virtual crossmatching. Unfortunately, high titer HLA antibodies can be missed or underestimated in the SAB assay as a result of interference with the d...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2019.04.019

    authors: Greenshields AL,Liwski RS

    更新日期:2019-07-01 00:00:00

  • High-resolution characterization of allelic and haplotypic HLA frequency distribution in a Spanish population using high-throughput next-generation sequencing.

    abstract::Next-generation sequencing (NGS) at the HLA-A, -B, -C, -DPA1, -DPB1, -DQA1, -DQB1, -DRB1 and -DRB3/4/5 loci was performed on 282 healthy unrelated individuals from different major regions of Spain. High-resolution HLA genotypes defined by full sequencing of class I loci and extended coverage of class II loci were obta...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2019.02.005

    authors: Montero-Martín G,Mallempati KC,Gangavarapu S,Sánchez-Gordo F,Herrero-Mata MJ,Balas A,Vicario JL,Sánchez-García F,González-Escribano MF,Muro M,Moya-Quiles MR,González-Fernández R,Ocejo-Vinyals JG,Marín L,Creary LE,Osoegawa K

    更新日期:2019-07-01 00:00:00

  • 4-Locus high-resolution HLA allele and haplotype frequencies in admixed population from Nicaragua.

    abstract::A total of 155 Nicaraguan Mestizos from across the country were genotyped at high-resolution for the human leukocyte antigen loci HLA-A, -B, -C, and -DRB1 using sequence-based typing methods. The respective allele and extended haplotype frequencies, as well as Hardy-Weinberg proportions were calculated. The most frequ...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2019.05.004

    authors: Arrieta-Bolaños E,Madrigal-Sánchez JJ,Stein JE,Moreira-Espinoza MJ,Paredes-Carias E,Vanegas-Padilla Y,Salazar-Sánchez L,Madrigal JA,Marsh SGE,Shaw BE

    更新日期:2019-07-01 00:00:00

  • B cells in chronic graft-versus-host disease.

    abstract::Allogeneic hematopoietic stem cell transplantation (alloHCT) is the definitive therapy for numerous otherwise incurable hematologic malignancies and non-malignant diseases. The genetic disparity between donor and recipient both underpins therapeutic effects and confers donor immune system-mediated damage in the recipi...

    journal_title:Human immunology

    pub_type: 杂志文章,评审

    doi:10.1016/j.humimm.2019.03.003

    authors: McManigle W,Youssef A,Sarantopoulos S

    更新日期:2019-06-01 00:00:00

  • Influence of the TNFSF4 rs1234315 polymorphism in the susceptibility to systemic lupus erythematosus and rheumatoid arthritis.

    abstract:OBJECTIVES:The tumour necrosis factor superfamily 4 (TNFSF4) is a candidate gene for autoimmune diseases. We investigated the relationship of this gene with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) in a Chinese Guangxi population. METHODS:A total of 294 patients with SLE, 210 with RA, and 282 h...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2018.11.006

    authors: Xu J,He Y,Wang J,Li X,Huang L,Li S,Qin X

    更新日期:2019-04-01 00:00:00

  • CD3+CD20+ T cells and their roles in human diseases.

    abstract::CD3+CD20+ T cells are a population of CD3+ T cells co-expressing CD20 that make up to ∼3-5% of the CD3+ T-cell compartment in the peripheral blood of human beings. In healthy individuals, CD3+CD20+ T cells are heterogeneous for containing a lower proportion of CD4+ cells, but produce higher levels of IL-17A and/or IFN...

    journal_title:Human immunology

    pub_type: 杂志文章,评审

    doi:10.1016/j.humimm.2019.01.001

    authors: Chen Q,Yuan S,Sun H,Peng L

    更新日期:2019-03-01 00:00:00

  • Infection with a virus generates a polyclonal immune response with broad alloreactive potential.

    abstract::Virus-specific T cells have been shown to cross-react with allogeneic HLA (allo-HLA) at a clonal level. However, the impact of a single virus on the allorepertoire has never been investigated at the polyclonal level. We made an inventory of the incidence and specificity of allo-HLA-cross-reactive-virus-specific CD8+ T...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2018.10.014

    authors: van den Heuvel H,van der Meer-Prins EMW,van Miert PPMC,Zhang X,Anholts JDH,Claas FHJ

    更新日期:2019-02-01 00:00:00

  • The association of de novo anti-HLA-DPB1 donor-specific antibody formation and primary graft failure after allogeneic hematopoietic cell transplantation.

    abstract::Despite advances in HLA matching, graft failure remains a serious complication after allogeneic hematopoietic cell transplantation (HCT). Pre-formed anti-HLA donor-specific antibodies (DSAs) have been associated with graft failure, but the impact of newly developing (de novo) anti-HLA antibodies on HCT outcomes remain...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2018.08.009

    authors: Hefazi M,Hogan WJ,Wakefield LL,Gandhi MJ

    更新日期:2018-12-01 00:00:00

  • Full-length next-generation sequencing of HLA class I and II genes in a cohort from Thailand.

    abstract::The human leukocyte antigen (HLA) genes are highly variable and are known to play an important role in disease outcomes, including infectious diseases. Prior knowledge of HLA polymorphisms in a population usually forms the basis for an effective case-control study design. As a prelude to future disease association ana...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2018.09.005

    authors: Geretz A,Ehrenberg PK,Bouckenooghe A,Fernández Viña MA,Michael NL,Chansinghakule D,Limkittikul K,Thomas R

    更新日期:2018-11-01 00:00:00

  • Increased T cell immunosenescence and accelerated maturation phenotypes in older kidney transplant recipients.

    abstract::Older kidney transplant recipients experience increased rates of infection and death, and less rejection, compared with younger patients. However, little is known about immune dysfunction in older compared with younger kidney transplant recipients and whether it is associated with infection. We evaluated T cell phenot...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2018.06.006

    authors: Schaenman JM,Rossetti M,Sidwell T,Groysberg V,Sunga G,Korin Y,Liang E,Zhou X,Abdalla B,Lum E,Bunnapradist S,Pham T,Danovitch G,Reed EF

    更新日期:2018-09-01 00:00:00

  • Killer cell immunoglobulin-like receptor genotypes in a Chilean population from Talca.

    abstract::Ninety healthy and unrelated volunteers were randomly selected to study the gene frequencies of Killer-cell immunoglobulin-like receptors (KIRs) in a Chilean (Talca) population. KIR typing was resolved by PCR-single specific primer (SSP), and their gene frequencies were calculated by direct counting of the number of p...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2018.06.007

    authors: Castro-Santos P,Verdugo RA,Díaz-Peña R

    更新日期:2018-09-01 00:00:00

  • Two sides of a coin: GG genotype of C7 provides protection against fibrosis severity while showing a higher risk for hepatocellular carcinoma in patients with hepatitis C.

    abstract::The complement system (CS) is a key element of immunity against pathogens but also seems to influence other events, such as tumorigenesis and tissue repair. Complement component 7 (C7) is a key component of the lytic pathway of CS, leading to the formation of the membrane attack complex (MAC). This study aimed to inve...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2018.06.009

    authors: de Lima RE,de Holanda Martins CM,do Carmo RF,Aroucha DCBL,Pereira LMMB,Vasconcelos LRS,Moura P

    更新日期:2018-09-01 00:00:00

  • CCR5Δ32 - A piece of protection in the inflammatory puzzle of multiple sclerosis susceptibility.

    abstract:BACKGROUND:Leucocyte infiltration and activation in the central nervous system (CNS) is an important step in the pathogenesis of multiple sclerosis (MS). The Chemokine receptor 5 (CCR5) is implicated in immune cell migration and cytokine release in the CNS, and it was demonstrated to strongly contribute to CNS inflamma...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2018.04.015

    authors: Troncoso LL,Pontillo A,Oliveira EML,Finkelszteijn A,Schneider S,Chies JAB

    更新日期:2018-08-01 00:00:00

  • IL-1β induces expression of costimulatory molecules and cytokines but not immune feedback regulators in dendritic cells.

    abstract::Dendritic cells play an important role in the initiation of immune reactions. Due to their high capacity to prime T-cell responses, the activation of dendritic cells must be tightly controlled. Because Interleukin-1β (IL-1β) is a key player in autoinflammatory diseases, we compared the ability of IL-1β to activate hum...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2018.06.002

    authors: Michelini S,Sarajlic M,Duschl A,Horejs-Hoeck J

    更新日期:2018-08-01 00:00:00

  • Heightened expression of HLA-DQB1 and HLA-DQB2 in pre-implantation biopsies predicts poor late kidney graft function.

    abstract:BACKGROUND:Accurate pre-transplant prediction of late graft function remains an unmet need in kidney transplantation. The aim of this study was to evaluate HLA genes expression levels in pre-implantation biopsies (PIB) of deceased donor kidneys as markers for long-term graft outcome. METHODS:HLA genes expression analy...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2018.05.002

    authors: Mine KL,Tedesco-Silva H,Mourão TB,Campos EF,Salzedas LA,Aguiar B,Felipe CR,Medina-Pestana JO,Gerbase-DeLima M

    更新日期:2018-08-01 00:00:00

  • Improving the performance of virtual crossmatch results by correlating with nationally-performed physical crossmatches: Obtaining additional value from proficiency testing activities.

    abstract:PURPOSE:When donor specific HLA antibodies (DSA) are identified, the predictive value of whether a certain strength of reactivity (mean fluorescence intensity, MFI) leads to a positive crossmatch is uncertain. To determine this, we compared the DSA MFI results we generated locally for nationally distributed proficiency...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2018.05.009

    authors: Wrenn SM,Marroquin CE,Hain DS,Harm SK,Pineda JA,Hammond PB,Shah DH,Hillyard SE,Fung MK

    更新日期:2018-08-01 00:00:00

  • Next Generation Sequencing in HLA haplotype distribution among Telugu speaking population from Andhra Pradesh, India.

    abstract:HLA A:B:C:DRB1:DQB1 allele and haplotype frequencies were determined among India, Andhra Pradesh, Telugu speaking population from South India by Next Generation Sequencing. 180 bone marrow registry donors and 6 cord blood units from Jeevan Stem Cell Foundation (part of Be The Cure Registry), Chennai, Tamilnadu state we...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2018.05.005

    authors: Seshasubramanian V,Manisekar NK,Sathishkannan AD,Naganathan C,Narayan S

    更新日期:2018-08-01 00:00:00

  • Limited impact of pre-existing donor specific HLA-antibodies (DSA) on long term allograft survival after first adult liver transplantation.

    abstract::The relevance of pre-existing HLA-antibodies (HLA-Ab) in liver transplantation (LTx) is controversial. While livers are allocated without HLA match or preoperative crossmatch testing, several studies point to an impact of donor specific antibodies (DSA) for acute rejection, bile duct complications or even graft loss. ...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2018.04.009

    authors: Koch M,Marget M,Sterneck M,Fischer L,Thude H,Nashan B

    更新日期:2018-07-01 00:00:00

  • Lack of evidence of association between IFNG and IL28B polymorphisms and QuantiFERON-CMV test results in seropositive transplant patients.

    abstract::The aim of this study was to analyze the relationship between the IFNG +874 T/A and IL28B (rs12979860) C/T polymorphisms and the secretion of IFNG by CD8+ T cells after stimulation with cytomegalovirus (CMV) peptides, measured using QuantiFERON-CMV (QF-CMV) assay. A total of 184 CMV-seropositive solid organ transplant...

    journal_title:Human immunology

    pub_type: 杂志文章

    doi:10.1016/j.humimm.2018.03.009

    authors: Aguado R,Páez-Vega A,Agüera ML,Montejo M,Guirado L,Fortún J,Suárez-Benjumea A,Len O,Fariñas MC,de Gracia C,Hernández D,Cobos-Ceballos MJ,Torre-Cisneros J,Cantisán S,Spanish Network for Research in Infectious Diseases and the

    更新日期:2018-06-01 00:00:00

  • Preclinical and clinical studies for transplant tolerance via the mixed chimerism approach.

    abstract::Based upon observations in murine models, we have developed protocols to induce renal allograft tolerance by combined kidney and bone marrow transplantation (CKBMT) in non-human primates (NHP) and in humans. Induction of persistent mixed chimerism has proved to be extremely difficult in major histocompatibility comple...

    journal_title:Human immunology

    pub_type: 杂志文章,评审

    doi:10.1016/j.humimm.2017.11.008

    authors: Sasaki H,Oura T,Spitzer TR,Chen YB,Madsen JC,Allan J,Sachs DH,Cosimi AB,Kawai T

    更新日期:2018-05-01 00:00:00

  • Mechanisms and biomarkers of immune quiescence in kidney transplantation.

    abstract::This review discusses the current understanding of biomarkers of immune quiescence based on reviews of published literature in kidney transplant operational tolerance and mechanistic studies based on a better characterization of the stable, well-functioning renal allograft. ...

    journal_title:Human immunology

    pub_type: 杂志文章,评审

    doi:10.1016/j.humimm.2018.01.016

    authors: Chan-On C,Liberto JM,Sarwal MM

    更新日期:2018-05-01 00:00:00

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