Improving the performance of virtual crossmatch results by correlating with nationally-performed physical crossmatches: Obtaining additional value from proficiency testing activities.

abstract：:HLA-Dw 19 antigen presenting cells express two different DR beta chains encoded respectively by DRB1 and DRB3 genes. In the present study we determined which of these two DR beta chains is recognized by DR-restricted T-cell clones. First we selected influenza-specific, DR-restricted T-cell clones of which restriction ...

journal_title：Human immunology

authors： Zeliszewski D,Tiercy JM,Dorval I,Kaplan C,Mach B,Sterkers G

更新日期：1990-08-01 00:00:00

abstract：:The intriguing observation made by Geczy et al. (1) showing the possibility of generating specific ankylosing spondylitis--cytotoxic T lymphocytes by presenting HLA-B27+AS+ cells as antigen-specific stimulator cells prompted us (by using Geczy's approach) to identify cytotoxic T lymphocytes specific for this apparent ...

journal_title：Human immunology

authors： Breur-Vriesendorp BS,Post FA,de Waal LP,Blokland E,Pool J,van der Linden S,Dekker-Saeys BJ,Goulmy E,Ivanyi P

更新日期：1989-07-01 00:00:00

abstract：:This study aimed at evaluating the functional activation and activating receptors expression on resting, short- and long-term NK and NK-like T cells from blood of ovarian neoplasia patients. Blood from patients with adnexal benign alterations (n = 10) and ovarian cancer (grade I-IV n = 14) were collected after signed ...

journal_title：Human immunology

authors： da Silva RF,Petta CA,Derchain SF,Alici E,Guimarães F

更新日期：2014-08-01 00:00:00

abstract：:Human T suppressor cells (Ts), capable of preventing autologous T helper cells (Th) from reacting against xenogeneic pig endothelial cells and pig APC can be generated in vitro. Ts derive from a population of CD3(+)CD8(+)CD28(-) T lymphocytes and specifically recognize the MHC class I antigens of the APC used for in v...

journal_title：Human immunology

authors： Ciubotariu R,Li J,Colovai AI,Platt JL,Cortesini R,Suciu Foca Cortesini N

更新日期：2001-05-01 00:00:00

abstract：:The purpose of this study was to examine the expression of human leukocyte antigen-G (HLA-G) in patients with systemic lupus erythematosus (SLE) and its relation with interleukin-10 (IL-10) production. The study included 50 female SLE patients and 59 healthy female donors. HLA-G expression in peripheral blood and cuta...

journal_title：Human immunology

authors： Rosado S,Perez-Chacon G,Mellor-Pita S,Sanchez-Vegazo I,Bellas-Menendez C,Citores MJ,Losada-Fernandez I,Martin-Donaire T,Rebolleda N,Perez-Aciego P

更新日期：2008-01-01 00:00:00

abstract：:PCR-based analyses were performed for the identification of HLA-B44 subgroups. Genomic DNA from six homozygous cell lines and 44 healthy individuals who had serologically tested positive for HLA-B44 was investigated for polymorphism in exons 2 and 3 of the HLA-B44 genes. Two primers were designed for specific amplific...

journal_title：Human immunology

authors： Yao Z,Keller E,Scholz S,McNicholas A,Volgger A,Albert ED

更新日期：1995-01-01 00:00:00

abstract：:The HLA-DQA1*05 with DQB1*02 alleles are a major risk factor for celiac disease (CD). To search for additional human leukocyte antigen (HLA) risk factors, we looked on the DR3-DQ2 risk haplotype, selected because it carries both DQ risk alleles in cis and is the more represented among CD patients. In a European consor...

journal_title：Human immunology

authors： Louka AS,Moodie SJ,Karell K,Bolognesi E,Ascher H,Greco L,Momigliano-Richiardi P,Partanen J,Ciclitira PJ,Sollid LM,European Genetics Cluster on Celiac Disease.

更新日期：2003-03-01 00:00:00

abstract：:This review focuses on the role of antigen-specific T cells that mediate active inhibition of immune responses over the past 35 years since their initial description. The field has experienced several changes in the accepted paradigm of such suppressor/regulatory T cells, from initial indications that such cells were ...

journal_title：Human immunology

authors： Kapp JA,Bucy RP

更新日期：2008-11-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is a primary malignant tumor of the liver. We evaluated the association of alleles and genotypes of polymorphisms of IL-18 (-607C/A and -137G/C), IFN-γ (+874T/A) and TNF-α (-238G/A and -308G/A) with the risk and severity of HCC. One-hundred-and-twelve patients with HCC and 202 healthy co...

journal_title：Human immunology

authors： Teixeira AC,Mendes CT Jr,Marano LA,Deghaide NH,Secaf M,Elias J Jr,Muglia V,Donadi EA,Martinelli AL

更新日期：2013-08-01 00:00:00

abstract：:The MHC in humans is a much studied region of the genome, the genes of which display a high rate of polymorphism and a high rate of linkage disequilibrium. Four families in which intra-class-I recombination has occurred have been analyzed with six polymorphic markers between HLA-A and -B in order to determine the full...

journal_title：Human immunology

authors： Crouau-Roy B,Bouissou C,Sommer E,Pontarotti P,Thomsen M

更新日期：1993-10-01 00:00:00

abstract：:Serological identification of a new HLA-Bw16 subtype, B39B, was made by the analysis of reaction patterns of many alloantisera and one monoclonal antibody. The B39B pattern of reactivity was shown to be distinct from HLA-Bw38, Bw39, and 8w57. Cytotoxicity testing before and after absorption suggests that the B39B spec...

journal_title：Human immunology

authors： Williams E,Alonso A,Doyle P,Okoye R,Ollier W,Festenstein H

更新日期：1985-09-01 00:00:00

abstract：:Bacterial sensing is crucial for appropriate response by the innate and adaptive immune system against invading microorganisms. Single nucleotide polymorphisms (SNPs) in genes involved in bacterial recognition, CARD15 and TLR4, increased the risk of inflammatory bowel disease (IBD) in a New Zealand Caucasian case-cont...

journal_title：Human immunology

authors： Petermann I,Huebner C,Browning BL,Gearry RB,Barclay ML,Kennedy M,Roberts R,Shelling AN,Philpott M,Han DY,Ferguson LR

更新日期：2009-06-01 00:00:00

abstract：AIMS:We studied the influence of IL-4 gene polymorphisms on the IPF phenotype, i.e., extent of radiological changes (HRCT interstitial (IS) and alveolar (AS) score) and histopathological markers from lung biopsies. PATIENTS AND METHODS:46 IPF patients underwent genotyping, 43 of them had HRCT and 14 patients had a sur...

journal_title：Human immunology

authors： Vasakova M,Sterclova M,Matej R,Olejar T,Kolesar L,Skibova J,Striz I

更新日期：2013-10-01 00:00:00

abstract：:Shellfish allergy affects approximately 2% of the population and can cause immediate hypersensitivity reactions such as urticaria, swelling, difficulty breathing, and, in some cases, anaphylaxis. Tropomyosin is the major shrimp allergen and binds IgE in two-thirds of patients. A total of 38 shrimp-allergic patients an...

journal_title：Human immunology

authors： Wang S,Delgado JC,Ravkov E,Eckels DD,Georgelas A,Pavlov IY,Cusick M,Sebastian K,Gleich GJ,Wagner LA

更新日期：2012-04-01 00:00:00

abstract：:We have investigated the presentation and CTL recognition of an HLA A*1101-restricted CTL peptide epitope AVFDRKSDAK (AVF)(3), derived from the EBV nuclear antigen (EBNA) 4, in the context of alleles belonging to the A3-supertype, A*0101, 0301, 1101, 3101, 3301, and 6801. The peptide binds to a A*6801 molecule as effi...

journal_title：Human immunology

authors： Levitsky V,Liu D,Southwood S,Levitskaya J,Sette A,Masucci MG

更新日期：2000-10-01 00:00:00

abstract：:Sarcoidosis is a multisystem granulomatous disorder of unknown etiology. Hereditary etiology has been proposed as a cause of the sarcoidosis, and some Human Leucocyte Antigen (HLA) alleles have been related to the diagnosis or severity of the disease. Löfgren's syndrome has been linked to patients with the DRB1*03 all...

journal_title：Human immunology

authors： da Costa CH,Silva VL,Fabricio-Silva GM,Usnayo M,Rufino R,Porto LC

更新日期：2013-10-01 00:00:00

abstract：:The Ia-like antigens of hybrids of the B-lymphoblastoid cell line (B-LCL) WI-L2 and a subline of the T-lymphoblastoid cell line (T-LCL) HSB were examined. Antigens of the HLA-DR and MT series were analyzed by indirect immunofluorescence with chimpanzee anti-DR sera and monoclonal antibodies, and antigens of the SB ser...

journal_title：Human immunology

authors： Howell DN,Hartzman RJ,Cresswell P

更新日期：1983-10-01 00:00:00

abstract：:Platelet alloimmunization may result in post-transfusion purpura, and during pregnancy may cause neonatal alloimmune thrombocytopenia (NAIT), with a frequency estimated at 1.3 per 1000 live births. The risk of morbidity is significant: 20% of affected infants have neurologic sequelae and the death rate is about 10%. A...

journal_title：Human immunology

authors： Semana G,Zazoun T,Alizadeh M,Morel-Kopp MC,Genetet B,Kaplan C

更新日期：1996-04-01 00:00:00

abstract：:A simple method for obtaining DNA from serum and plasma is described. Using appropriate primer pairs the polymorphic segments of HLA class II genes were amplified by the polymerase chain reaction (PCR) from this DNA, and typed using allele-specific oligonucleotide hybridization. When compared with DNA obtained from pe...

journal_title：Human immunology

authors： Martin M,Carrington M,Mann D

更新日期：1992-02-01 00:00:00

abstract：:We compared the T cell receptor (TCR) V beta gene family repertoire in peripheral blood mononuclear cells (PBMC) and lymph node (LN) cells from 7 human immunodeficiency virus (HIV)-infected patients and 3 seronegative healthy controls. Virtually all the V beta family specificities were represented in patient PBMC and ...

journal_title：Human immunology

authors： Mion M,Indraccolo S,Feroli F,Minuzzo S,Masiero S,Zamarchi R,Barelli A,Borri A,Chieco-Bianchi L,Amadori A

更新日期：1997-10-01 00:00:00

abstract：:The role of HLA antigens in lymphocyte differentiation is strongly suggested by the existence of a recently identified immunodeficiency associated with, and probably resulting from, the lack of expression of HLA-A, B, and C antigens as well as beta2 microglobulin on various cells of hematopoietic origin. This "bare ly...

journal_title：Human immunology

authors： Touraine JL,Bétuel H

更新日期：1981-03-01 00:00:00

abstract：:Celiac disease (CD) patients are intolerant to gluten, proteins in wheat, and related cereals. Virtually all patients are human leukocyte antigen (HLA)-DQ2 or HLA-DQ8 positive and several studies have demonstrated that CD4 T cells specific for (modified) gluten peptides bound to these HLA-DQ molecules are found in pat...

journal_title：Human immunology

authors： Stepniak D,Koning F

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVE:IL-10 is a potent anti-inflammatory cytokine that plays important roles in the pathogenesis of Behçet's disease (BD). Two genome-wide association studies have identified IL10 as a potential risk factor for BD. Here, we investigated the association between IL10 polymorphisms and BD in Chinese Han. METHODS:407...

journal_title：Human immunology

authors： Wu Z,Zheng W,Xu J,Sun F,Chen H,Li P,Chen S,Shen M,Zhang W,You X,Wu Q,Zhang F,Li Y

更新日期：2014-03-01 00:00:00

abstract：:In this study we have examined the results of probing with synthetic oligomers at the DR beta III locus, together with restriction fragment length polymorphisms defined by BglII digestion and a cDNA DR alpha probe, and Taq 1 digestion and a genomic DQ alpha probe. We have demonstrated heterogeneity of the human leukoc...

journal_title：Human immunology

authors： Gorski J,Niven MJ,Sachs JA,Mach B,Cassell PG,Festenstein H,Awad J,Hitman GA

更新日期：1987-12-01 00:00:00

abstract：UNLABELLED:Vesicoureteral reflux (VUR) is a common childhood problem, causing renal wounds and escalating the risk of renal deficiency and hypertension. A vast literature exists suggesting that genetic variations play a significant role in the pathogenesis of VUR. The aim of the present study was to estimate whether ge...

journal_title：Human immunology

authors： Kordi-Tamandani DM,Sadeghi-Bojd S,Torkamanzehi A

更新日期：2013-01-01 00:00:00

abstract：:A case-control study was performed to establish a potential association of two TNF-α gene promoter SNPs (-238G>A and -308G>A) with occurrence of type 1 Diabetes mellitus (T1DM) in Croatian population (174 patients and 193 healthy controls). Genotypes (obtained by polymerase chain reaction-restriction fragment length p...

journal_title：Human immunology

authors： Korolija M,Hadžija M,Medvidović EP,Pavkovic P,Kapitanović S,Renar IP,Hadžija MP

更新日期：2010-12-01 00:00:00

abstract：:We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 1217 Mexicans from the Mexico City Metropolitan Area living in the northern (N = 751), southern (N = 52), eastern (N = 79), western (N = 33), and central (N = 152) Mexico City, and rural communities (N = 150), to obtai...

journal_title：Human immunology

authors： Barquera R,Martínez-Álvarez JC,Hernández-Zaragoza DI,Bravo-Acevedo A,Juárez-Nicolás F,Arriaga-Perea AJ,Vega-Martínez MDR,Ortega-Yáñez A,Benítez-Arvizu G,Arrieta-Bolaños E,Clayton S,Juárez-Cortés ED,López-Gil C,García-Álvarez R

更新日期：2020-09-01 00:00:00

abstract：:DC-10 is a distinct subset of human tolerogenic dendritic cells (DCs) which express high levels of human leukocyte antigen-G (HLA-G). DC-10 could induce adaptive type 1 regulatory T cells through the IL-10 dependent ILT4/HLA-G signaling pathway. However, the significance of DC-10 in malignancies remains unclear. In th...

journal_title：Human immunology

authors： Xu DP,Shi WW,Zhang TT,Lv HY,Li JB,Lin A,Yan WH

更新日期：2016-09-01 00:00:00

abstract：:In this paper we briefly review three common immunological misconceptions that feature prominently among anti-vaccinationists, and in turn, fuel patient and parental concerns, questions, and fears about vaccines. In particular, this Perspective covers a brief history of the anti-vaccine movement, and three common fals...

journal_title：Human immunology

authors： Poland GA,Jacobson RM

更新日期：2012-08-01 00:00:00

abstract：:Homozygous carriers of CCR5-Δ32, a gene variant of CC-type chemokine receptor 5 (CCR5), are highly resistant to infections with human immunodeficiency virus type 1 (HIV-1) and therefore preferred stem cell donors for HIV-infected patients. We analyzed CCR5 typing data of 1,333,035 potential hematopoietic stem cell don...

journal_title：Human immunology

authors： Solloch UV,Lang K,Lange V,Böhme I,Schmidt AH,Sauter J

更新日期：2017-11-01 00:00:00