Abstract:
:In this study we have examined the results of probing with synthetic oligomers at the DR beta III locus, together with restriction fragment length polymorphisms defined by BglII digestion and a cDNA DR alpha probe, and Taq 1 digestion and a genomic DQ alpha probe. We have demonstrated heterogeneity of the human leukocyte antigen DR3 and close association of the DR alpha, DR beta III, and DX alpha genes. Two DR3-related preferential allelic associations have been identified, which may prove useful in family analysis as well as for investigations of DR3-related diseases.
journal_name
Hum Immunoljournal_title
Human immunologyauthors
Gorski J,Niven MJ,Sachs JA,Mach B,Cassell PG,Festenstein H,Awad J,Hitman GAdoi
10.1016/0198-8859(87)90018-8subject
Has Abstractpub_date
1987-12-01 00:00:00pages
273-8issue
4eissn
0198-8859issn
1879-1166pii
0198-8859(87)90018-8journal_volume
20pub_type
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