abstract：OBJECTIVES:The relationship between marijuana use and markers of chronic lung disease in people living with HIV (PLWH) is poorly understood. METHODS:We performed a cross-sectional analysis of the Examinations of HIV-Associated Lung Emphysema (EXHALE) study, including 162 HIV-positive patients and 138 participants with...

journal_title：HIV medicine

authors： Wenger DS,Triplette M,Shahrir S,Akgun KM,Wongtrakool C,Brown ST,Kim JW,Soo Hoo GW,Rodriguez-Barradas MC,Huang L,Feemster LC,Zifodya J,Crothers K

更新日期：2021-02-01 00:00:00

abstract：OBJECTIVES:We provide the first estimate of HIV prevalence among trans and gender-diverse people living in England and compare outcomes of people living with HIV according to gender identity. METHODS:We analysed a comprehensive national HIV cohort and a nationally representative self-reported survey of people accessin...

journal_title：HIV medicine

authors： Kirwan PD,Hibbert M,Kall M,Nambiar K,Ross M,Croxford S,Nash S,Webb L,Wolton A,Delpech VC

更新日期：2021-02-01 00:00:00

abstract：OBJECTIVES:Universal test and treat (UTT) is recommended for people living with HIV (PLHIV) to reduce morbidity/mortality and minimize transmission. However, concerns exist that this strategy may lead to more crowded hospitals, longer wait times and poorer service, adversely impacting health outcomes for clients with s...

journal_title：HIV medicine

authors： Boeke CE,Khan S,Walsh F,Hettema A,Lejeune C,Spiegelman D,Okello V,Harwell J,Mazibuko S,Bärnighausen T

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVES:Cardiovascular risk is increased in people living with HIV (PLWH). In HIV-uninfected populations, total absolute monocyte count (AMC) has been shown to be predictive of future cardiovascular events (CVEs). We sought to determine whether AMC predicts CVEs in PLWH independent of established and HIV-related car...

journal_title：HIV medicine

authors： Bogorodskaya M,Lyass A,Mahoney TF,Borowsky LH,Sen P,Swirski FK,Srinivasa S,Longenecker CT,Massaro JM,D'Agostino RB Sr,Triant VA

更新日期：2020-12-08 00:00:00

abstract：OBJECTIVES:With the prolonged survival time of AIDS patients, complications of various systems and organs of HIV infection are increasingly prominent. These diseases have become the major factors influencing the quality of life and prognosis of HIV-infected persons, and multidisciplinary cooperation treatment is urgent...

journal_title：HIV medicine

authors： Lin L,Li TS

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVES:To assess second-line antiretroviral therapy (ART) virological failure and HIV drug resistance-associated mutations (RAMs), in support of third-line regimen planning in Asia. METHODS:Adults > 18 years of age on second-line ART for ≥ 6 months were eligible. Cross-sectional data on HIV viral load (VL) and gen...

journal_title：HIV medicine

authors： Ross J,Jiamsakul A,Kumarasamy N,Azwa I,Merati TP,Do CD,Lee MP,Ly PS,Yunihastuti E,Nguyen KV,Ditangco R,Ng OT,Choi JY,Oka S,Sohn AH,Law M

更新日期：2020-11-05 00:00:00

abstract：OBJECTIVES:The aim of the study was to systematically review current studies reporting on clinical outcomes in people living with HIV (PLHIV) infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). METHODS:We conducted a systematic review using the Preferred Reporting Items for Systematic Reviews a...

journal_title：HIV medicine

authors： Cooper TJ,Woodward BL,Alom S,Harky A

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVES:We assessed whether changes at week 12 in markers of bone turnover, inflammation, and immune activation were associated with clinically important (≥ 5%) bone mineral density (BMD) loss from baseline to week 48 at the proximal femur (hip) and lumbar spine in the SECOND-LINE study. METHODS:We measured concent...

journal_title：HIV medicine

authors： Mwasakifwa GE,Amin J,White CP,Center JR,Kelleher A,Boyd MA

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVES:People with HIV (PWHIV) are likely to need therapies for comorbidities as they age. We assessed risk of drug-drug interactions (DDIs) in PWHIV. METHODS:The Climate-HIV electronic recording system was used to cross-sectionally analyse records from PWHIV aged ≥ 18 years attending four UK HIV units with a curr...

journal_title：HIV medicine

authors： Okoli C,Schwenk A,Radford M,Myland M,Taylor S,Darley A,Barnes J,Fox A,Grimson F,Reeves I,Munshi S,Croucher A,Boxall N,Benn P,Paice A,van Wyk J,Khoo S

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to describe a UK-wide process to assess adherence to guidelines for the routine investigation and monitoring of HIV-positive adults aged ≥ 50 years and provide clinical services with individual feedback to support improvement in quality of care. METHODS:The British HIV Association (...

journal_title：HIV medicine

authors： Ekong N,Curtis H,Ong E,Sabin CA,Chadwick D,British HIV Association (BHIVA) Audit and Standards Sub-Committee.

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVES:Socio-economic factors and lifestyle are known to differ across geographies and populations, which may result in distinct risk profiles for cardiovascular disease (CVD). This study assessed carotid intima-media thickness (CIMT), a proxy for CVD, and its determinants in two groups of people living with HIV (P...

journal_title：HIV medicine

authors： Roozen G,Vos AG,Tempelman HA,Venter W,Grobbee DE,Scheuermaier K,Klipstein-Grobusch K

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVES:In recent years, new technologies and new approaches to scale up HIV testing have emerged. The objective of this paper was to synthesize the body of recent evidence on strategies aimed at increasing the uptake and coverage of HIV testing outside of health care settings in the European Union (EU)/European Eco...

journal_title：HIV medicine

authors： Croxford S,Tavoschi L,Sullivan AK,Combs L,Raben D,Delpech V,Jakobsen SF,Amato-Gauci AJ,Desai S

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVES:Despite the availability of HIV testing guidelines to facilitate prompt diagnosis, late HIV diagnosis remains high across Europe. The study synthesizes recent evidence on HIV testing strategies adopted in health care settings in the European Union/European Economic Area (EU/EEA). METHODS:Preferred Reporting...

journal_title：HIV medicine

authors： Desai S,Tavoschi L,Sullivan AK,Combs L,Raben D,Delpech V,Jakobsen SF,Amato-Gauci AJ,Croxford S

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVES:In most lung screening programmes, only subjects ≥ 55 years old and smoking ≥ 30 pack-years are eligible to undergo chest low-dose computed tomography. Whether the same criteria should apply to people living with HIV (PLHIV) is uncertain, given the increased lung cancer risks associated with immunodeficiency...

journal_title：HIV medicine

authors： Makinson A,Tron L,Grabar S,Milleron B,Reynes J,Le Moing V,Morquin D,Lert F,Costagliola D,Guiguet M

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVES:Two-drug antiretroviral regimens based on lamivudine (3TC) plus either a protease inhibitor (PI) or dolutegravir (DTG) are becoming increasingly popular in switch strategies. Our goal was to derive a predictive score for virological failure (VF). METHODS:We retrospectively analysed data for a cohort of 587 ...

journal_title：HIV medicine

authors： Borghetti A,Moschese D,Cingolani A,Baldin G,Speziale D,Ciccullo A,Lombardi F,Emiliozzi A,Belmonti S,Antinori A,Cauda R,Di Giambenedetto S

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVES:The aim of this national audit was to assess adherence of services providing HIV care in the UK to national standards and guidelines regarding psychological support and the assessment of alcohol and recreational drug use (including chemsex drugs) in people living with HIV (PLWH). METHODS:Participating sites...

journal_title：HIV medicine

authors： Parry S,Curtis H,Chadwick D,British HIV Association Audit and Standards Sub-Committee.

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVES:Our objective was to identify patient factors associated with being untreated for hepatitis C virus (HCV) infection in HIV-coinfected patients. METHODS:A prospective longitudinal study was carried out. HIV-infected patients with active chronic HCV infection included in the HERACLES cohort (NCT02511496) cons...

journal_title：HIV medicine

authors： Rivero-Juarez A,Tellez F,Castaño-Carracedo M,Merino D,Espinosa N,Santos J,Macias J,Paniagua-García M,Zapata-Lopez A,Collado A,Gómez-Vidal MA,Perez-Stachowski J,Muñoz-Medina L,Fernandez-Fuertes E,Rivero A,Grupo de estudio de

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVES:Combination neonatal prophylaxis (CNP) is recommended in high-risk situations for the prevention of mother-to-child HIV transmission, although data on its safety are limited. The aim of the study was to identify whether neonatal prophylaxis (NP) type is associated with the risk of severe anaemia or neutropae...

journal_title：HIV medicine

authors： European Pregnancy and Paediatric HIV Cohort Collaboration (EPPICC) study group in EuroCoord.

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVES:As more HIV-positive individuals receive antiretroviral therapy (ART), payers are seeking options for covering these increased and sustained drug costs. Strategic use of available generic antiretroviral (ARV) formulations may be feasible. De-simplifying a single-tablet co-formulation (STF) into two or more t...

journal_title：HIV medicine

authors： Krentz HB,Campbell S,Lahl M,Gill MJ

更新日期：2019-03-01 00:00:00

abstract：:Initiating antiretroviral therapy (ART) as early as the day of HIV diagnosis is a strategy of increasing global interest to control the HIV epidemic and optimize the health of people living with HIV (PLWH). No detrimental effects of rapid-start ART have been identified in randomized controlled trials undertaken in low...

journal_title：HIV medicine

authors： Boyd MA,Boffito M,Castagna A,Estrada V

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVES:The aim was to determine the effectiveness of the serum cryptococcal antigen (CrAg) test in the diagnosis of concurrent cryptococcal meningitis (CM) and as a predictor of mortality in HIV-infected patients. METHODS:In this retrospective study, all HIV-infected patients admitted to Shanghai Public Health Cli...

journal_title：HIV medicine

authors： Chen J,Zhang R,Shen Y,Liu L,Qi T,Wang Z,Mehraj V,Routy JP,Lu H

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVES:Despite the huge success of antiretroviral therapy (ART), there is an ongoing HIV epidemic among men who have sex with men (MSM) in resource-rich countries. Understanding the driving factors underlying this process is important for curbing the epidemic. METHODS:We simulated the HIV epidemic in MSM in Switze...

journal_title：HIV medicine

authors： Kusejko K,Marzel A,Hampel B,Bachmann N,Nguyen H,Fehr J,Braun DL,Battegay M,Bernasconi E,Calmy A,Cavassini M,Hoffmann M,Böni J,Yerly S,Klimkait T,Perreau M,Rauch A,Günthard HF,Kouyos RD,Swiss HIV Cohort Study.

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVES:Up to 20% of HIV-related focal brain lesion (FBL) diagnoses cannot be determined without invasive procedures. In such cases, brain biopsy is an important step in the evaluation algorithm. The aims of this study were to describe the clinical outcomes of patients with FBL, the proportion of diagnoses confirmed...

journal_title：HIV medicine

authors： Acosta MC,Kundro M,Viloria G,Peressín Paz A,Morello F,Latorre F,Seoane E,Toibaro J,Losso M

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVES:In adults with horizontally acquired HIV infection, an inverted CD4:CD8 ratio is associated with persistent immune activation, size of HIV reservoir and predicts an increased risk of non-AIDS-defining adverse events. Normalization of this ratio with antiretroviral therapy (ART) is suboptimal in adults, despi...

journal_title：HIV medicine

authors： Seers T,Vassallo P,Pollock K,Thornhill JP,Fidler S,Foster C

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVES:Few studies have explored the optimal dosing for efavirenz in individuals from China. We investigated plasma efavirenz concentrations and their association with efficacy and tolerance of efavirenz 600 mg daily in Chinese HIV-infected adults. METHODS:An analysis was performed using plasma samples from 455 pa...

journal_title：HIV medicine

authors： Guo F,Cheng X,Hsieh E,Du X,Fu Q,Peng W,Li Y,Song X,Routy JP,Li T

更新日期：2018-05-15 00:00:00

abstract：OBJECTIVES:The aim of the study was to measure and compare national continuum of HIV care estimates in Europe and Central Asia in three key subpopulations: men who have sex with men (MSM), people who inject drugs (PWID) and migrants. METHODS:Responses to a 2016 European Centre for Disease Prevention and Control (ECDC)...

journal_title：HIV medicine

authors： Brown AE,Attawell K,Hales D,Rice BD,Pharris A,Supervie V,Van Beckhoven D,Delpech VC,An der Heiden M,Marcus U,Maly M,Noori T

更新日期：2018-05-08 00:00:00

abstract：OBJECTIVES:Despite adequate suppression of plasma HIV RNA, viral escape in cerebrospinal fluid (CSF) is widely reported. Rates of CSF HIV RNA escape vary in the literature. In persons living with HIV (PLWH) undergoing lumbar puncture examination for clinical reasons, we assessed rates of CSF HIV RNA escape. METHODS:Pe...

journal_title：HIV medicine

authors： Di Carlofelice M,Everitt A,Muir D,Winston A

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVES:The perceived threat of HIV transmission through spitting and biting is evidenced by the increasing use of "spit hoods" by Police Forces in the UK. In addition, a draft parliamentary bill has called for increased penalties for assaults on emergency workers, citing the risk of communicable disease transmissio...

journal_title：HIV medicine

authors： Cresswell FV,Ellis J,Hartley J,Sabin CA,Orkin C,Churchill DR

更新日期：2018-04-23 00:00:00

abstract：OBJECTIVES:The incidence of sexually transmitted infections (STIs) and HIV infection remains high in gay, bisexual, and other men who have sex with men (MSM) in the UK, and sexualized drug use ("chemsex") and injecting drug use ("slamsex") may play a part in this. We aimed to characterize HIV-positive MSM engaging in c...

journal_title：HIV medicine

authors： Pufall EL,Kall M,Shahmanesh M,Nardone A,Gilson R,Delpech V,Ward H,Positive Voices study group.

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVES:We evaluated the efficacy and tolerability of lamivudine + dolutegravir in a cohort of HIV-1 infected, treatment-experienced patients with undetectable HIV-RNA. METHODS:Time to treatment discontinuation (TD) and virological failure (VF) and their predictors were assessed in a multicenter cohort of HIV-1 inf...

journal_title：HIV medicine

authors： Borghetti A,Baldin G,Lombardi F,Ciccullo A,Capetti A,Rusconi S,Sterrantino G,Latini A,Cossu MV,Gagliardini R,De Luca A,Di Giambenedetto S

更新日期：2018-03-24 00:00:00

abstract：OBJECTIVES:The aim of the study was to assess indicator condition (IC) guided HIV testing in Estonia from 2012-2015. METHODS:We used Estonian Health Insurance Fund (EHIF) data. EHIF is the core purchaser of health care services in Estonia, covering health care costs for insured people (94% of the total population). Af...

journal_title：HIV medicine

authors： Rüütel K,Lemsalu L,Lätt S,OptTEST by HiE.

更新日期：2018-02-01 00:00:00

abstract：:The 2015 Paediatric European Network for Treatment of AIDS (PENTA) guidelines provide practical recommendations on the management of HIV-1 infection in children in Europe and are an update to those published in 2009. Aims of treatment have progressed significantly over the last decade, moving far beyond limitation of ...

journal_title：HIV medicine

authors： Bamford A,Turkova A,Lyall H,Foster C,Klein N,Bastiaans D,Burger D,Bernadi S,Butler K,Chiappini E,Clayden P,Della Negra M,Giacomet V,Giaquinto C,Gibb D,Galli L,Hainaut M,Koros M,Marques L,Nastouli E,Niehues T,Nog

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVES:HIV-associated neurocognitive disorders are highly prevalent, and physical activity (PA) is a modifiable behaviour that may affect neurocognitive function. Our objective was to determine the association between PA and neurocognitive function and the effect of HIV on this association. METHODS:PA was assessed...

journal_title：HIV medicine

authors： Monroe AK,Zhang L,Jacobson LP,Plankey MW,Brown TT,Miller EN,Martin E,Becker JT,Levine AJ,Ragin A,Sacktor NC

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:HIV treatment-as-prevention campaigns emphasize early diagnosis and immediate access to care and antiretroviral therapy for HIV-positive individuals in order to increase levels of plasma HIV RNA viral load (VL) suppression. However, the possible role of harm reduction-based programmes in this objective has n...

journal_title：HIV medicine

authors： Ti L,Dong H,Kerr T,Turje RB,Parashar S,Min JE,Montaner J,Wood E,Milloy MJ

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:Antiretroviral therapy (ART) has been associated with unfavourable lipid profile changes and increased risk of cardiovascular disease (CVD). With a growing population on ART in South Africa, there has been concern about the increase in noncommunicable diseases such as CVD. We determined risk factors associat...

journal_title：HIV medicine

authors： Jamieson L,Evans D,Brennan AT,Moyo F,Spencer D,Mahomed K,Maskew M,Long L,Rosen S,Fox MP

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:Single nucleotide polymorphisms in the cytochrome P450 (CYP) 2B6 gene have been associated with high interindividual variation in efavirenz pharmacokinetics. However, clinical data on the relationship of CYP2B6 polymorphisms with the occurrence of efavirenz-induced central nervous system (CNS) symptoms are l...

journal_title：HIV medicine

authors： Gallien S,Journot V,Loriot MA,Sauvageon H,Morlat P,Reynes J,Reliquet V,Chêne G,Molina JM,ANRS 099 ALIZE trial study group.

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to seek correlates of immune protection in HIV infection. We sought to elucidate the association between the presence of human leucocyte antigen (HLA) alleles, as well as killer immunoglobulin receptor (KIR) genotypes, and the susceptibility to HIV infection in a Spanish cohor...

journal_title：HIV medicine

authors： Rallón N,Restrepo C,Vicario JL,Del Romero J,Rodríguez C,García-Samaniego J,García M,Cabello A,Górgolas M,Benito JM

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:Efavirenz (EFV), a non-nucleoside reverse transcriptase inhibitor, is a drug that is frequently included in highly active antiretroviral therapy for treatment of HIV infection. Decreased bioavailability and increased toxicity limit its use. We report a formulation of efavirenz-loaded lactoferrin nanoparticle...

journal_title：HIV medicine

authors： Kumar P,Lakshmi YS,Kondapi AK

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVES:The Joint United Nations Programme on HIV/AIDS (UNAIDS)/World Health Organization (WHO) 90-90-90 goals propose that 90% of all people living with HIV should know their HIV status, 90% of those diagnosed should receive antiretroviral therapy (ART), and 90% of those should have durable viral suppression. We ha...

journal_title：HIV medicine

authors： Gisslén M,Svedhem V,Lindborg L,Flamholc L,Norrgren H,Wendahl S,Axelsson M,Sönnerborg A

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVES:Involvement of people living with HIV (PLHIV) in the design of HIV cure studies is important, given the potential risks to participants. We present results of an international survey of PLHIV to define these issues and inform cure research. METHODS:PLHIV were recruited in June-November 2014 through HIV webs...

journal_title：HIV medicine

authors： Simmons R,Kall M,Collins S,Cairns G,Taylor S,Nelson M,Fidler S,Porter K,Fox J,Collaborative HIV Eradication of viral Reservoirs (CHERUB) Survey collaboration.

更新日期：2017-02-01 00:00:00