听力与言语-语言病理学

行为科学

医学伦理学

你正在浏览INHALATION TOXICOLOGY期刊下所有文献
  • A single exposure to eucalyptus smoke sensitizes rats to the postprandial cardiovascular effects of a high carbohydrate oral load.

    abstract:OBJECTIVE:Previous studies have shown that air pollution exposure primes the body to heightened responses to everyday stressors of the cardiovascular system. The purpose of this study was to examine the utility of postprandial responses to a high carbohydrate oral load, a cardiometabolic stressor long used to predict c...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.1080/08958378.2020.1809572

    authors: Martin BL,Thompson LC,Kim YH,Snow SJ,Schladweiler MC,Phillips P,Harmon M,King C,Richards J,George I,W Kyle Martin,Haykal-Coates N,Gilmour MI,Kodavanti UP,Hazari MS,Farraj AK

    更新日期:2020-07-01 00:00:00

  • The impact of allergies and smoking status on nasal mucosa of hypertrophied turbinates - an immunohistologic analysis.

    abstract::Background: Allergies and smoking are common reasons for nasal mucosa inflammations, which in turn, cause nasal obstructions. Nevertheless, the impact of coexisting allergies and smoking on nasal mucosa inflammation has not been studied.Objectives: To study the impact of smoking with relation to allergies on nasal muc...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.1080/08958378.2020.1777226

    authors: Warman M,Tiomkin E,Huszar M,Halperin D,Asher I,Cohen O

    更新日期:2020-05-01 00:00:00

  • Associations of HMGB1 gene polymorphisms with risk of coal workers' pneumoconiosis susceptibility in Chinese Han population.

    abstract::Background: High-mobility group box 1 (HMGB1) protein plays an important pathogenic role in various diseases such as pulmonary fibrosis. However, the relationship between variation of HMGB1 gene and susceptibility to coal worker's pneumoconiosis (CWP) remains unclear. The objective of the study was to determine the as...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.1080/08958378.2020.1764153

    authors: Tang Y,Duan J,Wang Y,Yuan L

    更新日期:2020-03-01 00:00:00

  • Determination of the relative contribution of the non-dissolved fraction of ZnO NP on membrane permeability and cytotoxicity.

    abstract::Background: While the role of lysosomal membrane permeabilization (LMP) in NP-induced inflammatory responses has been recognized, the underlying mechanism of LMP is still unclear. The assumption has been that zinc oxide (ZnO)-induced LMP is due to Zn2+; however, little is known about the role of ZnO nanoparticles (NP)...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.1080/08958378.2020.1743394

    authors: Ziglari T,Anderson DS,Holian A

    更新日期:2020-02-01 00:00:00

  • Changes at global and site-specific DNA methylation of MLH1 gene promoter induced by waterpipe smoking in blood lymphocytes and oral epithelial cells.

    abstract::Objective: Cigarette tobacco smoking has been shown to cause cancer through different mechanisms that include epigenetic modulation of tumor-suppressor genes. In the present study, the association between global and MLH1 gene promoter methylation and waterpipe tobacco smoking was investigated. Materials and Methods: B...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.1080/08958378.2020.1754972

    authors: Sabi SH,Khabour OF,Alzoubi KH,Cobb CO,Eissenberg T

    更新日期:2020-02-01 00:00:00

  • PBPK modeling characterization of potential acute impairment effects from inhalation of ethanol during e-cigarette use.

    abstract::Objective: Ethanol is used as a solvent for flavoring chemicals in some electronic cigarette (e-cigarette) liquids (e-liquids). However, there are limited data available regarding the effects of inhalation of ethanol on blood alcohol concentration (BAC) during e-cigarette use. In this study, a modified physiologically...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.1080/08958378.2020.1720867

    authors: More SL,Thornton SA,Maskrey JR,Sharma A,de Gandiaga E,Cheng TJ,Fung ES,Bernal AJ,Madl AK

    更新日期:2020-01-01 00:00:00

  • Bedding-generated particulate matter: implications for rodent studies.

    abstract:OBJECTIVES:Rodents used in scientific research are typically housed in cages containing natural bedding materials. Despite extensive evidence of biological harm from inhaled particulate matter (PM), relatively little work has been performed to measure bedding-generated PM exposure in caged animals used in basic science...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.1080/08958378.2019.1694109

    authors: Hudda N,Durant JL,Nemeth A,Mann P,Petitto J,Brugge D,Nephew BC

    更新日期:2019-08-01 00:00:00

  • Surface area- and mass-based comparison of fine and ultrafine nickel oxide lung toxicity and augmentation of allergic response in an ovalbumin asthma model.

    abstract::Background: The correlation of physico-chemical properties with mechanisms of toxicity has been proposed as an approach to predict the toxic potential of the vast number of emerging nanomaterials. Although relationships have been established between properties and the acute pulmonary inflammation induced by nanomateri...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.1080/08958378.2019.1680775

    authors: Roach KA,Anderson SE,Stefaniak AB,Shane HL,Kodali V,Kashon M,Roberts JR

    更新日期:2019-07-01 00:00:00

  • Radiological progression and lung function decrements among silica-exposed ceramic workers: a longitudinal study.

    abstract::Objectives: This follow-up study set out to evaluate the natural course and radiographic progression of silicosis among ceramic workers and describe the risk factors related with disease progression. Materials and methods: We retrospectively analyzed the data of ceramic workers with silicosis who were referred to our ...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.1080/08958378.2019.1613459

    authors: Karataş M,Gündüzöz M,Büyükşekerci M,Özakıncı OG,Nadir Öziş T

    更新日期:2019-02-01 00:00:00

  • Waterpipe tobacco smoke distresses cardiovascular biomarkers in mice: alterations in protein expression of metalloproteinases, endothelin and myeloperoxidase.

    abstract::Introduction: Tobacco use is a major risk factor of cardiovascular diseases (CVD) and atherosclerosis in particular. The use of waterpipe smoking (WPS) is increasing due to the misperception that it is less harmful than cigarette smoking due to its flavor and the use of water as a filter. Thus, research that investiga...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.1080/08958378.2019.1606366

    authors: Rababa'h AM,Bsoul RW,Alkhatatbeh MJ,Alzoubi KH,Khabour OF

    更新日期:2019-02-01 00:00:00

  • A custom-built low-cost chamber for exposing rodents to e-cigarette aerosol: practical considerations.

    abstract::Objectives: To (1) design and build a low-cost exposure chamber system for whole-body exposure of rodents to electronic cigarette aerosol, (2) provide detailed instructions with particular focus on automated e-cigarette activation, and (3) develop a simple mathematical model for aerosol levels in the exposure chamber....

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.1080/08958378.2019.1698678

    authors: Hilpert M,Ilievski V,Coady M,Andrade-Gutierrez M,Yan B,Chillrud SN,Navas-Acien A,Kleiman NJ

    更新日期:2019-01-01 00:00:00

  • Incorporation of in vitro metabolism data and physiologically based pharmacokinetic modeling in a risk assessment for chloroprene.

    abstract::Objective: To develop a physiologically based pharmacokinetic (PBPK) model for chloroprene in the mouse, rat and human, relying only on in vitro data to estimate tissue metabolism rates and partitioning, and to apply the model to calculate an inhalation unit risk (IUR) for chloroprene.Materials and methods: Female B6C...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.1080/08958378.2020.1715513

    authors: Clewell HJ 3rd,Campbell JL,Van Landingham C,Franzen A,Yoon M,Dodd DE,Andersen ME,Gentry PR

    更新日期:2019-01-01 00:00:00

  • Time-course transcriptomic alterations reflect the pathophysiology of polyhexamethylene guanidine phosphate-induced lung injury in rats.

    abstract::Objective: Humidifier-disinfectant-induced lung injury is a new syndrome associated with a high mortality rate and characterized by severe hypersensitivity pneumonitis, acute interstitial pneumonia, or acute respiratory distress syndrome. Polyhexamethylene guanidine phosphate (PHMG-P), a guanidine-based antimicrobial ...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.1080/08958378.2019.1707912

    authors: Song MK,Kim DI,Lee K

    更新日期:2019-01-01 00:00:00

  • Concentration-time extrapolation of short-term inhalation exposure levels: dimethyl sulfide, a case study using a chemical-specific toxic load exponent.

    abstract:OBJECTIVE:Dimethyl sulfide (DMS, CAS 75-18-3) is an industrial chemical. It is both an irritant and neurotoxicant that may be life-threatening because of accidental release. The effects of DMS on public health and associated public health response depend on the exposure concentration and duration. However, currently, p...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.1080/08958378.2018.1551444

    authors: Demchuk E,Ball SL,Le SL,Prussia AJ

    更新日期:2018-01-01 00:00:00

  • Effect of prenatal waterpipe tobacco smoke on airway inflammation in murine model of asthma of adult offspring mice.

    abstract:OBJECTIVE:Worldwide popularity of waterpipe tobacco smoking has increased, including in pregnant women. This study investigates the effect of prenatal waterpipe tobacco smoke (WTS) exposure on airway inflammation in a murine model of asthma of adult offspring mice. MATERIALS AND METHODS:Pregnant BALB/c mice were expos...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.1080/08958378.2017.1385113

    authors: Al-Sawalha NA,Al-Bo'ul HF,Alzoubi KH,Khabour OF,Thanawala VJ

    更新日期:2017-07-01 00:00:00

  • Evaluation of the amount of nanoparticles emitted in welding fume from stainless steel using different shielding gases.

    abstract::The primary objective of this study was to correlate the emission of macro and nanoparticles released during the process of metal inert gas/metal active gas (MIG/MAG) of stainless steel with different gas mixtures. Using different gas mixtures with different heat inputs, it was possible to determine fume formation rat...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.1080/08958378.2017.1358778

    authors: Pacheco RP,Gomes JF,Miranda RM,Quintino ML

    更新日期:2017-05-01 00:00:00

  • Effects of maternal high-fat diet and sedentary lifestyle on susceptibility of adult offspring to ozone exposure in rats.

    abstract::Epidemiological and experimental data suggest that obesity exacerbates the health effects of air pollutants such as ozone (O3). Maternal inactivity and calorically rich diets lead to offspring that show signs of obesity. Exacerbated O3 susceptibility of offspring could thus be manifested by maternal obesity. Thirty-da...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.1080/08958378.2017.1342719

    authors: Gordon CJ,Phillips PM,Johnstone AFM,Schmid J,Schladweiler MC,Ledbetter A,Snow SJ,Kodavanti UP

    更新日期:2017-05-01 00:00:00

  • Cosmetic talc as a risk factor for pleural mesothelioma: a weight of evidence evaluation of the epidemiology.

    abstract:OBJECTIVE:Due to some historical (and inaccurate) reports that asbestos might be present in some cosmetic talc products, questions are occasionally raised regarding the potential pleural mesothelioma risks associated with cosmetic talc products. Our objective was to determine the incidence of pleural mesothelioma of in...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章,评审

    doi:10.1080/08958378.2017.1336187

    authors: Finley BL,Benson SM,Marsh GM

    更新日期:2017-03-01 00:00:00

  • Temporal structure/function variation in cultured differentiated human nasal epithelium associated with acute single exposure to tobacco smoke or E-cigarette vapor.

    abstract:OBJECTIVE:Mucociliary clearance sustains a baseline functionality and an "on demand" capability to upregulate clearance upon irritant exposure involving mucus hypersecretion and accelerated ciliary beat frequency (CBF) modulated by nitric oxide (NO). This study characterized these elements as well as cellular and exoge...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.1080/08958378.2017.1318985

    authors: Carson JL,Zhou L,Brighton L,Mills KH,Zhou H,Jaspers I,Hazucha M

    更新日期:2017-02-01 00:00:00

  • Effect of waterpipe tobacco smoking on airway inflammation in murine model of asthma.

    abstract:OBJECTIVE:There has been an increase in the popularity of waterpipe tobacco smoking (WTS) worldwide, especially in the younger population, including asthma patients. In this study, we investigated the effects of waterpipe smoking on airway inflammation, cytokine levels and oxidative stress markers in an antigen-driven ...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.1080/08958378.2017.1280105

    authors: Al-Sawalha NA,Migdadi AM,Alzoubi KH,Khabour OF,Qinna NA

    更新日期:2017-02-01 00:00:00

  • Modeling vascular inflammation and atherogenicity after inhalation of ambient levels of ozone: exploratory lessons from transcriptomics.

    abstract:BACKGROUND:Epidemiologic studies have linked inhalation of air pollutants such as ozone to cardiovascular mortality. Human exposure studies have shown that inhalation of ambient levels of ozone causes airway and systemic inflammation and an imbalance in sympathetic/parasympathetic tone. METHODS:To explore molecular me...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章,meta分析

    doi:10.1080/08958378.2017.1310333

    authors: Tham A,Lullo D,Dalton S,Zeng S,van Koeverden I,Arjomandi M

    更新日期:2017-02-01 00:00:00

  • Comparative inhalation toxicity of ethyltoluene isomers in rats and mice.

    abstract::The C9 alkylbenzenes, composed mostly of ethyltoluenes and trimethylbenzenes, comprise 75-90% of the naphtha fraction of crude oil. Occupational and environmental exposure to C9 alkylbenzenes occur via inhalation. We conducted short-term inhalation studies on the ethyltoluene isomers (2-, 3- or 4-) to select one isome...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.1080/08958378.2018.1430190

    authors: Roberts GK,Willson CJ,Olivera DS,Malarkey DE,Morgan DL

    更新日期:2017-01-01 00:00:00

  • Spirometry: a predictor of lung cancer among asbestos workers.

    abstract:OBJECTIVE:The significance of lung function as an independent risk factor for lung cancer remains unclear. The objective of the study is to answer the question if spirometry can identify patients at risk for lung cancer among people occupationally exposed to asbestos dust in the past. METHODS:In order to identify a gr...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.1080/08958378.2016.1272652

    authors: Świątkowska B,Szeszenia-Dąbrowska N

    更新日期:2017-01-01 00:00:00

  • Evaluating ECG and carboxyhemoglobin changes due to smoking narghile.

    abstract:PURPOSE:This study aimed to investigate whether increased carboxyhemoglobin (COHB) levels and ECG changes, which associated with fatal ventricular dysrhythmias, including increased QT, P-wave and T peak (Tp)-Tend (Te) dispersion, can be detected after smoking narghile, which is a traditional method of smoking tobacco t...

    journal_title:Inhalation toxicology

    pub_type: 临床试验,杂志文章

    doi:10.1080/08958378.2016.1224957

    authors: Yıldırım F,Çevik Y,Emektar E,Çorbacıoğlu ŞK,Katırcı Y

    更新日期:2016-10-01 00:00:00

  • "Rinse and trickle": a protocol for TEM preparation and investigation of inorganic fibers from biological material.

    abstract::The purpose of this work is to define a sample preparation protocol that allows inorganic fibers and particulate matter extracted from different biological samples to be characterized morphologically, crystallographically and chemically by transmission electron microscopy-energy dispersive spectroscopy (TEM-EDS). The ...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.1080/08958378.2016.1175527

    authors: Vigliaturo R,Capella S,Rinaudo C,Belluso E

    更新日期:2016-07-01 00:00:00

  • Subacute inhalation exposure to ozone induces systemic inflammation but not insulin resistance in a diabetic mouse model.

    abstract::Epidemiological studies suggest that diabetics may be more susceptible to the adverse health effects from exposure to high ambient concentrations of ozone, the primary oxidant gas in photochemical smog. While increased morbidity and mortality from ozone inhalation has been linked to disruption of normal cardiovascular...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.3109/08958378.2016.1146808

    authors: Ying Z,Allen K,Zhong J,Chen M,Williams KM,Wagner JG,Lewandowski R,Sun Q,Rajagopalan S,Harkema JR

    更新日期:2016-01-01 00:00:00

  • Cytotoxicity of diesel engine exhaust among the Chinese occupational population: a complement of cytokinesis-block micronucleus cytome.

    abstract::Diesel engine exhaust (DEE), a ubiquitous environmental pollutant, has been associated with adverse health effects. Revelation of cellular and molecular changes is critical for understanding environmental exposure-related diseases. Although the molecular-level effects of DEE exposure have been investigated, whether it...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.3109/08958378.2016.1162233

    authors: Zhang X,Xiao X,Duan H,Gao F,Li Y,Niu Y,Gao W,Wang H,Yu S,Zheng Y

    更新日期:2016-01-01 00:00:00

  • Cardiomyopathy confers susceptibility to particulate matter-induced oxidative stress, vagal dominance, arrhythmia and pulmonary inflammation in heart failure-prone rats.

    abstract::Acute exposure to ambient fine particulate matter (PM2.5) is tied to cardiovascular morbidity and mortality, especially among those with prior cardiac injury. The mechanisms and pathophysiological events precipitating these outcomes remain poorly understood but may involve inflammation, oxidative stress, arrhythmia an...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.3109/08958378.2014.995387

    authors: Carll AP,Haykal-Coates N,Winsett DW,Hazari MS,Ledbetter AD,Richards JH,Cascio WE,Costa DL,Farraj AK

    更新日期:2015-02-01 00:00:00

  • The negative effects of chronic exposure to isoflurane on spermatogenesis via breaking the hypothalamus-pituitary-gonadal equilibrium.

    abstract::This study aims to investigate the negative effects of chronic exposure to isoflurane on spermatogenesis and explore the underlying mechanisms. Sixty male rats were randomly allocated to two groups: control group, receiving no treatment, and anesthesia group, administrated exposure to isoflurane (2 ppm) for 25 consecu...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.3109/08958378.2015.1080772

    authors: Ding Y,Yu J,Qu P,Ma P,Yu Z

    更新日期:2015-01-01 00:00:00

  • Acrolein inhalation alters arterial blood gases and triggers carotid body-mediated cardiovascular responses in hypertensive rats.

    abstract:CONTEXT:Air pollution exposure affects autonomic function, heart rate, blood pressure and left ventricular function. While the mechanism for these effects is uncertain, several studies have reported that air pollution exposure modifies activity of the carotid body, the major organ that senses changes in arterial oxygen...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.3109/08958378.2014.984881

    authors: Perez CM,Hazari MS,Ledbetter AD,Haykal-Coates N,Carll AP,Cascio WE,Winsett DW,Costa DL,Farraj AK

    更新日期:2015-01-01 00:00:00

  • Generation and characterization of diesel engine combustion emissions from petroleum diesel and soybean biodiesel fuels and application for inhalation exposure studies.

    abstract::Biodiesel made from the transesterification of plant- and animal-derived oils is an important alternative fuel source for diesel engines. Although numerous studies have reported health effects associated with petroleum diesel emissions, information on biodiesel emissions are more limited. To this end, a program at the...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.3109/08958378.2015.1076910

    authors: Mutlu E,Nash DG,King C,Krantz TQ,Preston WT,Kooter IM,Higuchi M,DeMarini D,Linak WP,Gilmour MI

    更新日期:2015-01-01 00:00:00

  • Variability in ozone-induced pulmonary injury and inflammation in healthy and cardiovascular-compromised rat models.

    abstract::The molecular bases for variability in air pollutant-induced pulmonary injury due to underlying cardiovascular (CVD) and/or metabolic diseases are unknown. We hypothesized that healthy and genetic CVD-prone rat models will exhibit exacerbated response to acute ozone exposure dependent on the type and severity of disea...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.3109/08958378.2014.954169

    authors: Kodavanti UP,Ledbetter AD,Thomas RF,Richards JE,Ward WO,Schladweiler MC,Costa DL

    更新日期:2015-01-01 00:00:00

  • The in vitro and in vivo investigation of a novel small chamber dry powder inhalation delivery system for preclinical dosing to rats.

    abstract:PURPOSE:This research describes a novel "minitower" dry powder delivery system for nose-only delivery of dry powder aerosols to spontaneously breathing rats. METHODS:The minitower system forces pressurized air through pre-filled capsules to deliver aerosolized drug to four nose ports; three of which house spontaneousl...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.3109/08958378.2015.1089959

    authors: Sellers S,Horodnik W,House A,Wylie J,Mauser P,Donovan B

    更新日期:2015-01-01 00:00:00

  • Direct contact with particulate matter increases oxidative stress in different brain structures.

    abstract:INTRODUCTION:Several experimental and epidemiological studies have demonstrated the neurological adverse effects caused by exposure to air pollution, specifically in relation to pollutant particulate matter (PM). The objective of this study was to investigate the direct effect of PM in increased concentrations in diffe...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.3109/08958378.2015.1060278

    authors: Fagundes LS,Fleck Ada S,Zanchi AC,Saldiva PH,Rhoden CR

    更新日期:2015-01-01 00:00:00

  • Health effects after firing small arms comparing leaded and unleaded ammunition.

    abstract::A number of Norwegian soldiers have reported health problems after live-fire training using the HK416 rifle. The objective of this study was to characterize gaseous and particulate emissions from three different types of ammunition, and record the health effects after exposure to emissions from live-firing. Fifty-five...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.3109/08958378.2014.970783

    authors: Voie Ø,Borander AK,Sikkeland LI,Grahnstedt S,Johnsen A,Danielsen TE,Longva K,Kongerud J

    更新日期:2014-12-01 00:00:00

  • The increases in relative mRNA expressions of inflammatory cytokines and chemokines in splenic macrophages from rats exposed to multi-walled carbon nanotubes by whole-body inhalation for 13 weeks.

    abstract:BACKGROUND:The toxicity of multi-walled carbon nanotubes (MWCNT) may be related to the immune system. The objective of this study was to obtain information for immunotoxic mechanisms of MWCNT in situ. METHODS:Using whole-body inhalation, male and female rats were exposed to 0, 0.2, 1 or 5 mg MWCNT/m³ for 13 weeks. The...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.3109/08958378.2014.953275

    authors: Kido T,Tsunoda M,Kasai T,Sasaki T,Umeda Y,Senoh H,Yanagisawa H,Asakura M,Aizawa Y,Fukushima S

    更新日期:2014-10-01 00:00:00

  • The National Environmental Respiratory Center (NERC) experiment in multi-pollutant air quality health research: III. Components of diesel and gasoline engine exhausts, hardwood smoke and simulated downwind coal emissions driving non-cancer biological resp

    abstract::An approach to identify causal components of complex air pollution mixtures was explored. Rats and mice were exposed by inhalation 6 h daily for 1 week or 6 months to dilutions of simulated downwind coal emissions, diesel and gasoline exhausts and wood smoke. Organ weights, hematology, serum chemistry, bronchoalveolar...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.3109/08958378.2014.920440

    authors: Mauderly JL,Seilkop SK

    更新日期:2014-09-01 00:00:00

  • The role of N-acetylcysteine in the management of acute and chronic pulmonary complications of sulfur mustard: a literature review.

    abstract:CONTEXT:Sulfur mustard exposure, as the most widely used chemical weapon, can lead to acute and long-term pulmonary complications via various pathways, such as triggering an imbalance between the oxidant and antioxidant system. Currently, there is no validated antidote, chemoprophylaxis and curative modality for pulmon...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章,评审

    doi:10.3109/08958378.2014.920439

    authors: Shohrati M,Karimzadeh I,Saburi A,Khalili H,Ghanei M

    更新日期:2014-08-01 00:00:00

  • Exposure to ozone induces a systemic inflammatory response: possible source of the neurological alterations induced by this gas.

    abstract::The World Health Organization identified urban outdoor air pollution as the eighth highest mortality risk factor in high-income countries. Exposure to ambient pollutants such as ozone (O3) increases the number of hospital admissions. O3 is a highly reactive gas that reacts with cells lining the airways, producing the ...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.3109/08958378.2014.922648

    authors: González-Guevara E,Martínez-Lazcano JC,Custodio V,Hernández-Cerón M,Rubio C,Paz C

    更新日期:2014-07-01 00:00:00

  • Local and systemic tolerability of a 2'O-methoxyethyl antisense oligonucleotide targeting interleukin-4 receptor-α delivery by inhalation in mouse and monkey.

    abstract::Antisense oligonucleotides (ASOs) bind and facilitate degradation of RNA and inhibit protein expression in pathways not easily targeted with small molecules or antibodies. Interleukin (IL)-4 and IL-13 potentiate signaling through the shared IL-4 receptor-α (IL-4Rα) subunit of their receptors. ASO targeting of IL-4Rα m...

    journal_title:Inhalation toxicology

    pub_type: 杂志文章

    doi:10.3109/08958378.2014.907587

    authors: Fey RA,Templin MV,McDonald JD,Yu RZ,Hutt JA,Gigliotti AP,Henry SP,Reed MD

    更新日期:2014-07-01 00:00:00

195 条记录 1/5 页 « 12345 »