abstract：INTRODUCTION:Women living with HIV are required to transition into the prevention of mother-to-child transmission of HIV (PMTCT) services when they become pregnant and back to ART services after delivery. Transition can be a vulnerable time when many women are lost from HIV care yet there is little guidance on the opti...

journal_title：Journal of the International AIDS Society

authors： Phillips TK,Teasdale CA,Geller A,Ng'eno B,Mogoba P,Modi S,Abrams EJ

更新日期：2021-01-01 00:00:00

abstract：INTRODUCTION:While there is a global consensus on monitoring Human Immunodeficiency Virus (HIV) treatment progress, there has been less attention to the degree of consistency of the measurement of HIV prevention programmes-and the global prevention response is not on-track to achieve 2020 goals. In this paper, we asses...

journal_title：Journal of the International AIDS Society

authors： Sekimitsu S,DePasse J,Morrison M,Mahy M,Rice B,Earle K,Daley K,Larson J,Carter A,Garnett GP,Holmes CB

更新日期：2020-12-01 00:00:00

abstract：INTRODUCTION:Preventive therapy is essential for reducing tuberculosis (TB) burden among people living with HIV (PLWH) in high-burden settings. Short-course preventive therapy regimens, such as three-month weekly rifapentine and isoniazid (3HP) and one-month daily rifapentine and isoniazid (1HP), may help facilitate up...

journal_title：Journal of the International AIDS Society

authors： Ferguson O,Jo Y,Pennington J,Johnson K,Chaisson RE,Churchyard G,Dowdy D

更新日期：2020-10-01 00:00:00

abstract：INTRODUCTION:The majority of new HIV infections occur through mucosal transmission. The availability of readily applicable and accessible platforms for anti-retroviral (ARV) delivery is critical for the prevention of HIV acquisition through sexual transmission in both women and men. There is a compelling need for devel...

journal_title：Journal of the International AIDS Society

authors： Crakes KR,Herrera C,Morgan JL,Olstad K,Hessell AJ,Ziprin P,LiWang PJ,Dandekar S

更新日期：2020-10-01 00:00:00

abstract：INTRODUCTION:Most clinical trials for new antiretroviral (ARV) agents are conducted among narrowly defined adult populations. Only after safety and efficacy have been clearly demonstrated among adults living with HIV are trials including adolescents, children and infants conducted. This approach contributes to signific...

journal_title：Journal of the International AIDS Society

authors： Rojo P,Carpenter D,Venter F,Turkova A,Penazzato M

更新日期：2020-09-01 00:00:00

abstract：INTRODUCTION:HIV continues to devastate the adolescent population in sub-Saharan Africa (SSA). The complex array of interpersonal, social, structural and system-level obstacles specific to adolescents have slowed progress in prevention and treatment of HIV in this population. The field of implementation science holds p...

journal_title：Journal of the International AIDS Society

authors： Sturke R,Vorkoper S,Bekker LG,Ameyan W,Luo C,Allison S,Walker D,Kapogiannis B,Guay L

更新日期：2020-09-01 00:00:00

abstract：INTRODUCTION:As adolescents transition from childhood to adulthood, they experience major physical, social and psychological changes, and are at heightened risk for developing mental health conditions and engaging in health-related risk behaviours. For adolescents living with HIV (ALHIV), these risks may be even more p...

journal_title：Journal of the International AIDS Society

authors： Laurenzi CA,Skeen S,Gordon S,Akin-Olugbade O,Abrahams N,Bradshaw M,Brand A,du Toit S,Melendez-Torres GJ,Tomlinson M,Servili C,Dua T,Ross DA

更新日期：2020-09-01 00:00:00

abstract：INTRODUCTION:HIV-controllers have the ability to spontaneously maintain viraemia at low or undetectable levels in the absence of antiretroviral treatment. Furthermore, HIV-controllers seem to have a superior capacity to spontaneously clear hepatitis C virus (HCV) compared to non HIV-controllers. Some of these subjects ...

journal_title：Journal of the International AIDS Society

authors： Dominguez-Molina B,Tarancon-Diez L,Milanés-Guisado Y,Genebat M,Resino S,Rodriguez C,Gonzalez-García J,Rallón N,Pernas M,Casado C,Lopez-Galíndez C,León A,Benito JM,García F,Del Romero J,Viciana P,Lopez-Cortes LF,Leal M,

更新日期：2020-09-01 00:00:00

abstract：INTRODUCTION:Older adults living with HIV (OALHIV; ≥50 years) who use drugs face unique needs and challenges that compromise their health and wellbeing due to the structural and environmental barriers they experience, in addition to being disproportionately affected by comorbidities. Nevertheless, research on this popu...

journal_title：Journal of the International AIDS Society

authors： Chayama KL,Ng C,McNeil R

更新日期：2020-08-01 00:00:00

abstract：INTRODUCTION:Nearly 40 years into the HIV epidemic, the persistence of HIV stigma is a matter of grave urgency. Discrimination (i.e. enacted stigma) in healthcare settings is particularly problematic as it deprives people of critical healthcare services while also discouraging preventive care seeking by confirming fear...

journal_title：Journal of the International AIDS Society

authors： Smith MK,Xu RH,Hunt SL,Wei C,Tucker JD,Tang W,Luo D,Xue H,Wang C,Yang L,Yang B,Li L,Joyner BL Jr,Sylvia SY

更新日期：2020-08-01 00:00:00

abstract：INTRODUCTION:There is great interest for integrating care for non-communicable diseases (NCDs) into routine HIV services in sub-Saharan Africa (SSA) due to the steady rise of the number of people who are ageing with HIV. Suggested health system approaches for intervening on these comorbidities have mostly been normativ...

journal_title：Journal of the International AIDS Society

authors： Kintu A,Sando D,Okello S,Mutungi G,Guwatudde D,Menzies NA,Danaei G,Verguet S

更新日期：2020-06-01 00:00:00

abstract：INTRODUCTION:Women in sub-Saharan Africa spend a substantial portion of their reproductive lives pregnant and/or breastfeeding (P/BF), yet they have limited options to prevent HIV during these maternal stages. In preparation for phase 3b prevention trials in P/BF women, we explored attitudes about using a vaginal ring ...

journal_title：Journal of the International AIDS Society

authors： van der Straten A,Ryan JH,Reddy K,Etima J,Taulo F,Mutero P,Taylor J,Piper J,Musara P,MTN-041\/MAMMA Study Team.

更新日期：2020-06-01 00:00:00

abstract：INTRODUCTION:Men who have sex with men (MSM) and transgender women (TGW) are two key populations (KPs) in Thailand at high risk for HIV. Uptake and scale-up of pre-exposure prophylaxis (PrEP) among them has been slow. We used data from Princess PrEP, Thailand's largest KP-led PrEP programme, to operationalize PrEP serv...

journal_title：Journal of the International AIDS Society

authors： Ramautarsing RA,Meksena R,Sungsing T,Chinbunchorn T,Sangprasert T,Fungfoosri O,Meekrua D,Sumalu S,Pasansai T,Bunainso W,Wongsri T,Mainoy N,Colby D,Avery M,Mills S,Vannakit R,Phanuphak P,Phanuphak N

更新日期：2020-06-01 00:00:00

abstract：INTRODUCTION:Engaging at-risk men in HIV prevention programs and services is a current priority, yet there are few effective ways to identify which men are at highest risk or how to best reach them. In this study we generated multi-factor profiles of HIV acquisition/transmission risk for men in Durban, South Africa, to...

journal_title：Journal of the International AIDS Society

authors： Gottert A,Pulerwitz J,Heck CJ,Cawood C,Mathur S

更新日期：2020-06-01 00:00:00

abstract：INTRODUCTION:Current healthcare systems fail to provide adequate HIV services to men. In Zambia, 25% of adult men living with HIV were unaware of their HIV status in 2018, and 12% of those who were unaware of their HIV statu were not receiving antiretroviral therapy (ART) due to pervasive barriers to HIV testing servic...

journal_title：Journal of the International AIDS Society

authors： Mwango LK,Stafford KA,Blanco NC,Lavoie MC,Mujansi M,Nyirongo N,Tembo K,Sakala H,Chipukuma J,Phiri B,Nzangwa C,Mwandila S,Nkwemu KC,Saadani A,Mwila A,Herce ME,Claassen CW

更新日期：2020-06-01 00:00:00

abstract：INTRODUCTION:Global guidelines emphasize the ethical obligation of investigators to help participants in HIV-endpoint trials reduce HIV risk by offering an optimal HIV prevention package. Oral pre-exposure prophylaxis (PrEP) has increasingly become part of state-of-the-art HIV prevention. Here we describe the process o...

journal_title：Journal of the International AIDS Society

authors： Beesham I,Welch JD,Heffron R,Pleaner M,Kidoguchi L,Palanee-Phillips T,Ahmed K,Baron D,Bukusi EA,Louw C,Mastro TD,Smit J,Batting JR,Malahleha M,Bailey VC,Beksinska M,Donnell D,Baeten JM,ECHO Trial Consortium.

更新日期：2020-05-01 00:00:00

abstract：INTRODUCTION:High levels of HIV seroconcordance at the population level reduce the potential for effective HIV transmission. However, the level of HIV seroconcordance is largely unknown among heterosexual couples in sub-Saharan Africa. We aimed to quantify the population level HIV seroconcordance in stable heterosexual...

journal_title：Journal of the International AIDS Society

authors： Kim HY,Harling G,Vandormael A,Tomita A,Cuadros DF,Bärnighausen T,Tanser F

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION:HIV testing is an essential prerequisite for accessing treatment with antiretroviral therapy or prevention using pre-exposure prophylaxis. Internet distribution of HIV self-tests is a novel approach, and data on the programmatic cost of this approach are limited. We analyse the costs and cost-effectiveness...

journal_title：Journal of the International AIDS Society

authors： Shrestha RK,Chavez PR,Noble M,Sansom SL,Sullivan PS,Mermin JH,MacGowan RJ

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION:Viral load testing is essential to manage HIV disease, especially in infants and children. Early infant diagnosis is performed using nucleic-acid testing in children under 18 months. Resource-limited health systems face severe challenges to scale-up both viral load and early infant diagnosis to unprecedent...

journal_title：Journal of the International AIDS Society

authors： Vubil A,Nhachigule C,Loquiha O,Meggi B,Mabunda N,Bollinger T,Sacks JA,Jani I,Vojnov L

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION:In 2013, the World Health Organization (WHO) recommended initiating combination ART (cART) in all adults with HIV and CD4+ lymphocyte counts (CD4) <500 cells/mm3 . In 2015, this was updated to recommend cART initiation in all patients with HIV, regardless of CD4 count. Implementation of these guidelines in...

journal_title：Journal of the International AIDS Society

authors： Crabtree-Ramírez BE,Caro-Vega Y,Belaunzarán-Zamudio PF,Shepherd BE,Rebeiro PF,Veloso V,Cortes CP,Padgett D,Gotuzzo E,Sierra-Madero J,McGowan CC,Person AK,Caribbean, Central, South America Network for HIV Epidemiology (CCASAnet).

更新日期：2019-12-01 00:00:00

abstract：INTRODUCTION:Integrating standardized measures of HIV stigma and discrimination into research studies of emerging HIV prevention approaches could enhance uptake and retention of these approaches, and care and treatment for people living with HIV (PLHIV), by informing stigma mitigation strategies. We sought to develop a...

journal_title：Journal of the International AIDS Society

authors： Stangl AL,Lilleston P,Mathema H,Pliakas T,Krishnaratne S,Sievwright K,Bell-Mandla N,Vermaak R,Mainga T,Steinhaus M,Donnell D,Schaap A,Bock P,Ayles H,Hayes R,Hoddinott G,Bond V,Hargreaves JR,HPTN 071 (PopART) Study Tea

更新日期：2019-12-01 00:00:00

abstract：INTRODUCTION:The relative efficacy of different antiretroviral (ART) regimens has been extensively evaluated in the context of clinical trials, using HIV viral load (VL) measurements at pre-specified timepoints after ART onset. However, data from real-life studies using combined longitudinal measurements of cumulative ...

journal_title：Journal of the International AIDS Society

authors： Pascom AR,Pinho RE,Rick F,Veras NM,Perini FB,Meireles MV,Pereira GF,Benzaken AS,Avelino-Silva VI

更新日期：2019-11-01 00:00:00

abstract：INTRODUCTION:Gonorrhoea and chlamydia cases have been rising among gay, bisexual and other men who have sex with men (MSM) over the last decade. The majority of cases are extragenital and occur at the oropharynx and anorectum. The aim of this narrative review was to review the risk factors and mode of transmission for ...

journal_title：Journal of the International AIDS Society

authors： Chow EP,Fairley CK

更新日期：2019-08-01 00:00:00

abstract：INTRODUCTION:Achieving UNAIDS 90-90-90 targets is a crucial step towards ending the AIDS epidemic. Many countries have published estimates of care cascades, although often with methodological limitations. We describe an approach that used the national HIV registry as a starting-point to determine the HIV care cascade a...

journal_title：Journal of the International AIDS Society

authors： Ho ZJM,Huang F,Wong CS,Chua L,Ma S,Chen MI,Lee VJ

更新日期：2019-07-01 00:00:00

abstract：INTRODUCTION:As prevalence of undiagnosed HIV declines, it is unclear whether testing programmes will be cost-effective. To guide their HIV testing programmes, countries require appropriate metrics that can be measured. The cost-per-diagnosis is potentially a useful metric. METHODS:We simulated a series of setting-sce...

journal_title：Journal of the International AIDS Society

authors： Phillips AN,Cambiano V,Nakagawa F,Bansi-Matharu L,Wilson D,Jani I,Apollo T,Sculpher M,Hallett T,Kerr C,van Oosterhout JJ,Eaton JW,Estill J,Williams B,Doi N,Cowan F,Keiser O,Ford D,Hatzold K,Barnabas R,Ayles H,Me

更新日期：2019-07-01 00:00:00

abstract：INTRODUCTION:WHO recommends assisted partner notification (APN) for people living with HIV (PLHIV). These services have not been widely scaled in Central Asia. We describe the results from an APN intervention implemented within a programme focused on PLHIV and people who inject drugs in Kazakhstan, the Kyrgyz Republic ...

journal_title：Journal of the International AIDS Society

authors： Little KM,Kan M,Samoylova O,Rsaldinova A,Saliev D,Ishokov F,Gray R,Hasen NS

更新日期：2019-07-01 00:00:00

abstract：INTRODUCTION:To achieve epidemic control of HIV by 2030, countries aim to meet 90-90-90 targets to increase knowledge of HIV-positive status, initiation of antiretroviral therapy (ART) and viral suppression by 2020. We assessed the progress towards these targets from 2014 to 2016 in South Africa as expanded treatment p...

journal_title：Journal of the International AIDS Society

authors： Lippman SA,El Ayadi AM,Grignon JS,Puren A,Liegler T,Venter WDF,Ratlhagana MJ,Morris JL,Naidoo E,Agnew E,Barnhart S,Shade SB

更新日期：2019-06-01 00:00:00

abstract：INTRODUCTION:Better knowledge about fertility desires/intentions among HIV-serodiscordant partners who face unique challenges when considering childbearing may be helpful in the development of targeted reproductive interventions. The aim of this systematic review was to synthesize the published literature regarding the...

journal_title：Journal of the International AIDS Society

authors： Martins A,Alves S,Chaves C,Canavarro MC,Pereira M

更新日期：2019-05-01 00:00:00

abstract：INTRODUCTION:Safer conception strategies minimize HIV risk during condomless sex to become pregnant. Gaps remain in understanding the acceptability, feasibility and choices HIV-serodiscordant couples make when multiple safer conception options are available. METHODS:We conducted a pilot study of a comprehensive safer ...

journal_title：Journal of the International AIDS Society

authors： Heffron R,Ngure K,Velloza J,Kiptinness C,Quame-Amalgo J,Oluch L,Thuo N,Njoroge J,Momanyi R,Gakuo S,Mbugua S,Morrison S,Haugen H,Chohan B,Celum C,Baeten JM,Mugo N

更新日期：2019-04-01 00:00:00

abstract：INTRODUCTION:Limited data exist on acceptability of candidate pre-exposure prophylaxis (PrEP) regimens among US women. We evaluated PrEP experiences, attitudes and future use intentions among sexually active women who completed the US-based HIV Prevention Trials Network 069/AIDS Clinical Trials Group 5305 study. METHO...

journal_title：Journal of the International AIDS Society

authors： Amico KR,Ramirez C,Caplan MR,Montgomery BE,Stewart J,Hodder S,Swaminathan S,Wang J,Darden-Tabb NY,McCauley M,Mayer KH,Wilkin T,Landovitz RJ,Gulick R,Adimora AA,HPTN 069\/A5305 Study Team and HPTN Women at Risk Committee.

更新日期：2019-03-01 00:00:00

abstract：INTRODUCTION:HIV incidence among men who have sex with men (MSM) is high in China. Pre-exposure prophylaxis (PrEP) is a promising mean to prevent HIV transmission but it is not widely available in China. We conducted a large Internet-based online survey to assess the willingness of Chinese MSM to take PrEP and associat...

journal_title：Journal of the International AIDS Society

authors： Han J,Bouey JZ,Wang L,Mi G,Chen Z,He Y,Viviani T,Zhang F

更新日期：2019-02-01 00:00:00

abstract：INTRODUCTION:Since June 2016, the national HIV programme in Malawi has adopted Universal Test and Treat (UTT) guidelines requiring that all persons who test HIV positive will be referred to start antiretroviral therapy (ART). Although there is strong evidence from clinical trials that early initiation of ART leads to r...

journal_title：Journal of the International AIDS Society

authors： Alhaj M,Amberbir A,Singogo E,Banda V,van Lettow M,Matengeni A,Kawalazira G,Theu J,Jagriti MR,Chan AK,van Oosterhout JJ

更新日期：2019-02-01 00:00:00

abstract：INTRODUCTION:People living with HIV (PLHIV) on antiretroviral therapy (ART) experience high rates of non-communicable diseases (NCDs). These co-morbidities often accumulate and older adults may suffer from multimorbidity. Multimorbidity has been associated with loss of quality of life, polypharmacy, and increased risk ...

journal_title：Journal of the International AIDS Society

authors： Castilho JL,Escuder MM,Veloso V,Gomes JO,Jayathilake K,Ribeiro S,Souza RA,Ikeda ML,de Alencastro PR,Tupinanbas U,Brites C,McGowan CC,Grangeiro A,Grinsztejn B

更新日期：2019-01-01 00:00:00

abstract：INTRODUCTION:Treat-all is being implemented in several African settings, in accordance with 2015 World Health Organisation guidelines. The factors known to undermine adherence to antiretroviral therapy (ART) may change in the context of Treat-all, where people living with HIV (PLHIV) increasingly initiate ART at earlie...

journal_title：Journal of the International AIDS Society

authors： Horter S,Wringe A,Thabede Z,Dlamini V,Kerschberger B,Pasipamire M,Lukhele N,Rusch B,Seeley J

更新日期：2019-01-01 00:00:00

abstract：INTRODUCTION:HIV controllers (HIC) maintain viraemia at low levels without antiretroviral treatment and have small HIV reservoirs. Nevertheless, they are heterogeneous regarding their risk of infection progression. The study of reservoirs can help elucidate this control. This study aimed to explore the factors implicat...

journal_title：Journal of the International AIDS Society

authors： Avettand-Fenoel V,Bayan T,Gardiennet E,Boufassa F,Lopez P,Lecuroux C,Noel N,Trémeaux P,Monceaux V,Autran B,Meyer L,Saez-Cirion A,Lambotte O,Rouzioux C,CODEX ANRS Cohort Study Group.

更新日期：2019-01-01 00:00:00

abstract：INTRODUCTION:Setting and monitoring progress towards targets for HIV control is critical in ensuring responsive programmes. Here, we explore how to apply targets for reduction in HIV incidence to local settings and which indicators give the strongest signal of a change in incidence in the population and are therefore m...

journal_title：Journal of the International AIDS Society

authors： Anderson SJ,Garnett GP,Enstone J,Hallett TB

更新日期：2018-11-01 00:00:00

abstract：INTRODUCTION:The Good Participatory Practice (GPP): Guidelines for Biomedical HIV Prevention Trials, second edition (2011) were developed to provide clinical trial sponsors and implementers with a formal stakeholder engagement framework. As one of the largest African research institutes, Wits Reproductive Health and HI...

journal_title：Journal of the International AIDS Society

authors： Baron D,Essien T,Pato S,Magongo M,Mbandazayo N,Scorgie F,Rees H,Delany-Moretlwe S

更新日期：2018-10-01 00:00:00

abstract：INTRODUCTION:Population-level improvements in knowledge about HIV may reduce the stigma attached to HIV and ensure maximal uptake of HIV prevention initiatives. The extent to which levels of HIV knowledge in the general population of sub-Saharan Africa have changed in the current era of antiretroviral therapy (ART) sca...

journal_title：Journal of the International AIDS Society

authors： Chan BT,Tsai AC

更新日期：2018-07-01 00:00:00

abstract：INTRODUCTION:HIV self-testing (HIVST) offers an alternative to facility-based HIV testing services, particularly for populations such as men who have sex with men (MSM) who may fear accessing testing due to stigma, discrimination and criminalization. Innovative HIV testing approaches are needed to meet the goal of 90% ...

journal_title：Journal of the International AIDS Society

authors： Tun W,Vu L,Dirisu O,Sekoni A,Shoyemi E,Njab J,Ogunsola S,Adebajo S

更新日期：2018-07-01 00:00:00

abstract：INTRODUCTION:The universal test and treat strategy (UTT) was developed to maximize the proportion of all HIV-positive individuals on antiretroviral treatment (ART) and virally suppressed, assuming that it will lead to a reduction in HIV incidence at the population level. The evolution over time of the cross-sectional H...

journal_title：Journal of the International AIDS Society

authors： Larmarange J,Diallo MH,McGrath N,Iwuji C,Plazy M,Thiébaut R,Tanser F,Bärnighausen T,Pillay D,Dabis F,Orne-Gliemann J,ANRS 12249 TasP Study Group.

更新日期：2018-07-01 00:00:00