abstract：PURPOSE:To provide a comprehensive analysis of mtDNA quantity in D5 and D6 blastocysts, as well as a further insight to the origin of delayed blastocyst development. METHODS:A retrospective cohort analysis of 829 D5 and 472 D6 blastocysts from 460 patients who underwent in vitro fertilization (IVF) with next-generatio...

journal_title：Journal of assisted reproduction and genetics

authors： Wu FS,Weng SP,Shen MS,Ma PC,Wu PK,Lee NC

更新日期：2021-01-20 00:00:00

abstract：:The most common reason for in vitro fertilization (IVF) cycle cancelation is a lack of quality gametes available for intracytoplasmic sperm injection (ICSI). Here we present the successful fertility treatment of the couple affected by obstructive azoospermia combined with suboptimal response to controlled ovarian stim...

journal_title：Journal of assisted reproduction and genetics

authors： Holubcová Z,Otevřel P,Koudelka M,Kloudová S

更新日期：2021-01-20 00:00:00

abstract：PURPOSE:To provide a validated method to identify copy number variation (CNV) in regions of the Y chromosome of infertile men by next-generation sequencing (NGS). METHODS:Semen analysis was used to determine the quality of semen and diagnose infertility. Deletion of the azoospermia factor (AZF) region in the Y chromos...

journal_title：Journal of assisted reproduction and genetics

authors： Liu X,Zhang H,Zhang X,Zhang H,Jiang Y,Liu R,Fei J,Wang Y,Yu Y

更新日期：2021-01-16 00:00:00

abstract：RESEARCH QUESTION:Granulosa cells (GCs) surrounding oocytes are crucial for follicular growth, oocyte development, ovulation, and luteinization under the dynamic co-stimulation of follicle stimulating hormone (FSH) and luteinizing hormone (LH). This study aimed to investigate the effect of LH levels on GCs in preovulat...

journal_title：Journal of assisted reproduction and genetics

authors： Wan YT,Liu S,Zhao SK,Luo YY,Lv YS,Qu DN,Liu MH,Li Y

更新日期：2021-01-14 00:00:00

abstract：PURPOSE:To evaluate whether endometrial compaction using sequential transvaginal ultrasound is associated with improved live birth rates in medicated single euploid frozen embryo transfer (FET) cycles. METHODS:Prospective observational cohort study at a private fertility clinic. Patients who underwent FETs between Jan...

journal_title：Journal of assisted reproduction and genetics

authors： Riestenberg C,Quinn M,Akopians A,Danzer H,Surrey M,Ghadir S,Kroener L

更新日期：2021-01-03 00:00:00

abstract：PURPOSE:To identify, appraise, and assess clinical practice guidelines informing patient counseling on female age-related fertility decline. METHODS:Searched electronic database records from January 1, 2006, to September 10, 2018, and professional society websites. The search terms included iterations of "guideline," ...

journal_title：Journal of assisted reproduction and genetics

authors： Trawick E,Pecoriello J,Quinn G,Goldman KN

更新日期：2021-01-01 00:00:00

abstract：PURPOSE:There is no consensus yet in the literature on an optimal luteinizing hormone (LH) level for human chorionic gonadotrophin (hCG) trigger timing in patients undergoing frozen-thawed embryo transfer (FET) with modified natural cycles (mNC). The objective of our study was to compare the clinical results of hCG tri...

journal_title：Journal of assisted reproduction and genetics

authors： Kahraman S,Sahin Y

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:Assess the effect of class III (body mass index [BMI, kg/m2] 40-49.9) and class IV obesity (≥ 50) on clinical pregnancy and live birth outcomes after first oocyte retrieval and fresh embryo transfer cycle. DESIGN:Cohort study SETTING: Academic center PATIENTS: Patients undergoing their first oocyte retrieval...

journal_title：Journal of assisted reproduction and genetics

authors： Romanski PA,Bortoletto P,Magaoay B,Chung A,Rosenwaks Z,Spandorfer SD

更新日期：2020-11-16 00:00:00

abstract：:Embryo implantation is accompanied by a potent inflammatory response, and a gradient of cytokines and chemokines produced by endometrial cells supports the embryo-endometrial interaction. C-reactive protein (CRP) serves as an early marker of inflammation and recent studies have illustrated that controlled ovarian hype...

journal_title：Journal of assisted reproduction and genetics

authors： Diba-Bagtash F,Farshbaf-Khalili A,Ghasemzadeh A,Lotz L,Fattahi A,Shahnazi M,Dittrich R

更新日期：2020-11-01 00:00:00

abstract：PURPOSE:A genome-wide association study conducted in the Han Chinese population identified three single nucleotide variants rs12097821, rs2477686, and rs10842262 as being significantly associated with non-obstructive azoospermia. Our aim was to evaluate the possible association between these susceptibility loci and idi...

journal_title：Journal of assisted reproduction and genetics

authors： Nemanja V,Zorana D,Nevena K,Suzana M,Ivan V,Branko B,Mirka D,Dusanka SP,Goran B

更新日期：2020-11-01 00:00:00

abstract：PURPOSE:To assess longitudinal trends in in vitro fertilization (IVF) patients' choices for disposing of cryopreserved embryos. METHODS:This is a retrospective cohort study of embryo disposition forms submitted between January 2000 and February 2020 at a university-based fertility clinic. Primary outcome was dispositi...

journal_title：Journal of assisted reproduction and genetics

authors： Alexander VM,Riley JK,Jungheim ES

更新日期：2020-11-01 00:00:00

abstract：PURPOSE:To compare morphokinetic parameters and quality of embryos derived from GnRH antagonist ICSI cycles triggered either with GnRH agonist or standard hCG between matched groups of patients. METHODS:Morphokinetic parameters of embryos derived from matched first GnRH antagonist ICSI cycles triggered by GnRH agonist...

journal_title：Journal of assisted reproduction and genetics

authors： Oron G,Sapir O,Wertheimer A,Shufaro Y,Bar-Gil R,Margalit T,Shlush E,Ben-Haroush A

更新日期：2020-11-01 00:00:00

abstract：:Artificial intelligence (AI) has been proposed as a potential tool to help address many of the existing problems related with empirical or subjective assessments of clinical and embryological decision points during the treatment of infertility. AI technologies are reviewed and potential areas of implementation of algo...

journal_title：Journal of assisted reproduction and genetics

authors： Swain J,VerMilyea MT,Meseguer M,Ezcurra D,Fertility AI Forum Group.

更新日期：2020-11-01 00:00:00

abstract：:A recent study published in Human Reproduction claimed that uterine lavage offers a non-surgical, minimally invasive strategy for the recovery of human embryos from fertile women who do not want or need IVF for medical reasons but who desire preimplantation genetic testing (PGT) for embryos. To prove this hypothesis, ...

journal_title：Journal of assisted reproduction and genetics

authors： Murtinger M,Wirleitner B,Hradecký L,Comploj G,Okhowat J,Spitzer D,Stadler J,Haidbauer R,Schuff M,Yildirim S,Soepenberg T,Eibner K,Gagsteiger F

更新日期：2020-11-01 00:00:00

abstract：PURPOSE:To evaluate whether miR-148a-3p overexpression is associated with disrupted decidualization of recurrent implantation failure (RIF). METHODS:Endometrial miRNA and mRNA expression profiles during the implantation window derived from women with and without RIF were identified using microarray and RT-qPCR. Immort...

journal_title：Journal of assisted reproduction and genetics

authors： Zhang Q,Ni T,Dang Y,Ding L,Jiang J,Li J,Xia M,Yu N,Ma J,Yan J,Chen ZJ

更新日期：2020-10-01 00:00:00

abstract：PURPOSE:To investigate the potential etiologies of premature ovarian insufficiency (POI) and diminished ovarian reserve (DOR). METHODS:Fourteen women with sporadic POI and 6 women with DOR were enrolled. We used whole-exome sequencing (WES) and bioinformatics analysis to identify variants in a subset of 599 selected P...

journal_title：Journal of assisted reproduction and genetics

authors： Tang R,Yu Q

更新日期：2020-10-01 00:00:00

abstract：RESEARCH QUESTION:Does a freeze-all strategy improve live birth rates in women of different age groups? DESIGN:Retrospective cohort study of 1882 first embryo transfer cycles, performed between January 2013 and December 2015. Reproductive outcomes between fresh (FRESH) or frozen (FROZEN) embryo transfers were compared...

journal_title：Journal of assisted reproduction and genetics

authors： Lattes K,López S,Checa MA,Brassesco M,García D,Vassena R

更新日期：2020-10-01 00:00:00

abstract：PURPOSE:Although ovarian tissue transportation has been validated for up to 24 h, there is no standard protocol to date. We aimed to elucidate how existing media currently used for ovarian tissue transportation affect ovarian tissue metabolism and cell viability. METHODS:Cow ovarian fragments were immersed in 0.9% NaC...

journal_title：Journal of assisted reproduction and genetics

authors： Vilela JMV,Dolmans MM,Maruhashi E,Blackman MCNM,Sonveaux P,Miranda-Vilela AL,Amorim CA

更新日期：2020-10-01 00:00:00

abstract：PURPOSE:To evaluate if preimplantation genetic testing (PGT) improves the odds of a healthy live birth amongst recipients of fresh donor oocytes. METHODS:We performed a retrospective cohort study including in vitro fertilization cycles of women using fresh donor oocytes reported to the Society for Assisted Reproductiv...

journal_title：Journal of assisted reproduction and genetics

authors： Roeca C,Johnson R,Carlson N,Polotsky AJ

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:To perform complex preimplantation genetic tests (PGT) for aneuploidy screening, Robertsonian translocation, HLA-matching, and X-linked hyper IgM syndrome (XHIGM) caused by a novel mutation c.156 G>T of CD40LG gene. METHODS:Reverse transcription PCR (RT-PCR) and Sanger sequencing were carried out to confirm th...

journal_title：Journal of assisted reproduction and genetics

authors： Huang S,Niu Y,Li J,Gao M,Zhang Y,Yan J,Ma S,Gao X,Gao Y

更新日期：2020-08-01 00:00:00

abstract：PURPOSE:Higher serum estradiol levels occur in women undergoing assisted reproductive technology (ART) owing to ovarian stimulation. Here, we investigated the association between maternal serum estradiol levels and the intellectual development of offspring conceived with ART. METHODS:A total of 204 singletons born aft...

journal_title：Journal of assisted reproduction and genetics

authors： Zhou CL,Xu GF,Yang Q,Wang HH,Guo MX,Xiong YM,Guo XY,Hou M,Jin LY,Sheng JZ,He L,Jin L,Huang HF

更新日期：2020-08-01 00:00:00

abstract：PURPOSE:To identify gender differences in leadership and academic rank within academic reproductive endocrinology (REI) programs with fellowships in the USA. METHODS:Official institutional websites of the 2017-2018 American Board of Obstetrics and Gynecology (ABOG)-accredited reproductive endocrinology fellowship prog...

journal_title：Journal of assisted reproduction and genetics

authors： Selter JH,Spurlin EE,Brady PC

更新日期：2020-08-01 00:00:00

abstract：PURPOSE:To evaluate the association of objectively measured physical activity (PA) and sedentary behaviour before and during in vitro fertilization (IVF) with controlled ovarian stimulation (COS) and pregnancy outcomes. METHODS:This longitudinal study involved 107 infertile women undergoing IVF treatment. PA and seden...

journal_title：Journal of assisted reproduction and genetics

authors： Sõritsa D,Mäestu E,Nuut M,Mäestu J,Migueles JH,Läänelaid S,Ehrenberg A,Sekavin A,Sõritsa A,Salumets A,Ortega FB,Altmäe S

更新日期：2020-08-01 00:00:00

abstract：:MicroRNAs (miRNAs) are small, about 22 nucleotides, non-coding RNAs which regulate a wide range of gene expression during post-transcriptional stage. They are released into intra- and extracellular microenvironments and play vital roles in different physiological and pathological pathways. Due to easy accessibility, d...

journal_title：Journal of assisted reproduction and genetics

authors： Qasemi M,Amidi F

更新日期：2020-08-01 00:00:00

abstract：:The incorporation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing into patient care algorithms has been proposed to mitigate risk. However, the two main professional societies for human reproduction (ESHRE and ASRM) appear divergent on their clinical utility and whether they should be adopted. ...

journal_title：Journal of assisted reproduction and genetics

authors： La Marca A,Nelson SM

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVE:Combination of transcriptomic and retrospective clinical data, to assess anti-Mullerian hormone (AMH) functionality at a cumulus cell level and evaluate AMH potential as a suitable marker for IVF outcomes (oocytes retrieved, number of day 3 embryos, gestation outcomes). DESIGN:Raw RNA-sequencing data of cumu...

journal_title：Journal of assisted reproduction and genetics

authors： Kastora SL,Triantafyllidou O,Kolovos G,Kastoras A,Sigalos G,Vlahos N

更新日期：2020-07-01 00:00:00

abstract：PURPOSE:The aim of this study was to compare the levels of hyperglycosylated human chorionic gonadotropin (hCG-H) secreted from balanced and unbalanced human embryos. METHODS:Single-step culture media samples from 155 good quality embryos, derived from 90 good prognosis patients undergoing intracytoplasmic sperm injec...

journal_title：Journal of assisted reproduction and genetics

authors： Parvanov D,Nikolova D,Ganeva R,Nikolova K,Vasileva M,Rangelov I,Pancheva M,Serafimova M,Staneva R,Hadjidekova S,Scarpellini F,Stamenov G

更新日期：2020-06-01 00:00:00

abstract：:Treatment for cancer has the potential to significantly diminish fertility and, further, to negatively impact the obstetrical outcomes of pregnancies that do occur. Cancer survivors have decreased rates of fertility and increased rates of pregnancy complications, such as preterm birth and low birth weight, after expos...

journal_title：Journal of assisted reproduction and genetics

authors： Garg D,Johnstone EB,Lomo L,Fair DB,Rosen MP,Taylor R,Silver B,Letourneau JM

更新日期：2020-06-01 00:00:00

abstract：PURPOSE:The aim of this study is to provide data on the practice of Luteal Phase Oocyte Retrieval (LuPOR). The authors assess cell-free DNA levels in follicular fluid (ff cfDNA) from poor responders undergoing natural cycles, and comparing it to respective data originating from follicular phase oocyte retrievals. METH...

journal_title：Journal of assisted reproduction and genetics

authors： Konstantinos S,Petroula T,Evangelos M,Polina G,Argyro G,Sokratis G,Anna R,Andrianos N,Agni P,Michael K,Konstantinos P,George M,Mara S

更新日期：2020-05-01 00:00:00

abstract：PURPOSE:This study aimed to investigate the clinical outcomes of morula stage transfer derived from post-thawed cleavage embryos undergoing overnight culture in frozen embryo transfer (FET) cycles. METHODS:We performed a retrospective study that included 392 FET cycles with 784 thawed embryos undergoing overnight cult...

journal_title：Journal of assisted reproduction and genetics

authors： Hui D,Han X,Wang X,Ren W,Lei X,Liu J,Dong L,Li H

更新日期：2020-04-01 00:00:00

abstract：PURPOSE:The aim of the present study was to improve the in vitro maturation (IVM) procedure using oocytes from surplus ovarian tissue after fertility preservation. METHODS:Twenty-five patients aged 17-37 years were included in the study. Maturation was compared between oocytes collected in HEPES-buffered medium or sal...

journal_title：Journal of assisted reproduction and genetics

authors： Nikiforov D,Junping C,Cadenas J,Shukla V,Blanshard R,Pors SE,Kristensen SG,Macklon KT,Colmorn L,Ernst E,Bay-Bjørn AM,Ghezelayagh Z,Wakimoto Y,Grøndahl ML,Hoffmann E,Andersen CY

更新日期：2020-04-01 00:00:00

abstract：PURPOSE:To investigate the relation between mutations in ciliopathy-related SPAG6 and RSPH3 and male infertility with severe asthenoteratospermia characterized by multiple flagellar malformations and reveal the intracytoplasmic sperm injection (ICSI) outcomes of those primary ciliary dyskinesia (PCD) patients. METHODS...

journal_title：Journal of assisted reproduction and genetics

authors： Wu H,Wang J,Cheng H,Gao Y,Liu W,Zhang Z,Jiang H,Li W,Zhu F,Lv M,Liu C,Tan Q,Zhang X,Wang C,Ni X,Chen Y,Song B,Zhou P,Wei Z,Zhang F,He X,Cao Y

更新日期：2020-04-01 00:00:00

abstract：:Infertility is a major health problem across the world. One of the main reasons for male infertility are defects in sperm. Semen analysis is the most common test utilized to evaluate male fertility and since it suffers from multiple drawbacks, reproduction scientists have tried to find new molecular markers for detect...

journal_title：Journal of assisted reproduction and genetics

authors： Daneshmandpour Y,Bahmanpour Z,Hamzeiy H,Mazaheri Moghaddam M,Mazaheri Moghaddam M,Khademi B,Sakhinia E

更新日期：2020-04-01 00:00:00

abstract：:With the increased rate of stable remission after gonadotoxic cancer treatment, new methods of fertility preservation are required in order to provide the best possible care for oncological patients. Here, we report an original case of euploid blastocyst cryopreservation after in vitro maturation of ovarian tissue ooc...

journal_title：Journal of assisted reproduction and genetics

authors： Kirillova A,Kovalskaya E,Brovkina O,Ekimov A,Bunyaeva E,Gordiev M,Mishieva N,Nazarenko T,Abubakirov A,Sukikh G

更新日期：2020-04-01 00:00:00

abstract：PURPOSE:To examine the intra- and inter-individual variability in fatty acid composition of follicular fluid (FF) of 23 patients undergoing assisted reproductive treatment. METHODS:The average coefficient of variation within each patient (CVw) and intra-class correlation coefficient (ICC) values of FF fatty acid compo...

journal_title：Journal of assisted reproduction and genetics

authors： Liu YJ,Vlaeminck B,Tilleman K,Chouinard PY,Gervais R,De Sutter P,Fievez V

更新日期：2020-03-01 00:00:00

abstract：:With more young breast cancer survivors, a trend toward having children later in life, and improvements in assisted reproductive technology (ART), fertility preserving techniques are of growing importance prior to initiation of gonadotoxic treatments. The American Society for Clinical Oncology (ASCO) updated their Fer...

journal_title：Journal of assisted reproduction and genetics

authors： Hampe ME,Rhoton-Vlasak AS

更新日期：2020-03-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy of preimplantation genetic testing (PGT) for α- and β-double thalassemia combined with aneuploidy screening using next-generation sequencing (NGS). METHODS:An NGS-based PGT protocol was performed between 2017 and 2018 for twelve couples, each of which carried both α- and β-thalassemia ...

journal_title：Journal of assisted reproduction and genetics

authors： Chen D,Shen X,Wu C,Xu Y,Ding C,Zhang G,Xu Y,Zhou C

更新日期：2020-03-01 00:00:00

abstract：PURPOSE:To use conflict resolution analysis on the conflict between proponents and opponents of preimplantation genetic testing for aneuploidy (PGT-A), previously called preimplantation genetic screening (PGS). METHODS:Considered in conflict analysis a case study, we reviewed the English literature based on key-word s...

journal_title：Journal of assisted reproduction and genetics

authors： Mochizuki L,Gleicher N

更新日期：2020-03-01 00:00:00

abstract：PURPOSE:This study sought to identify a disease-related gene in a consanguineous Chinese family in which there were two premature ovarian insufficiency (POI) sisters. METHOD:We used whole-exome sequencing and Sanger sequencing to identify the disease-causing gene. Results were verified using an assay of mutant protein...

journal_title：Journal of assisted reproduction and genetics

authors： Peng T,Lv C,Tan H,Huang J,He H,Wang Y,Zeng M,Yi D,Li J,Deng H,Shi X,Xiao H

更新日期：2020-02-01 00:00:00

abstract：PURPOSE:To assess testicular mRNA and protein expression levels of MRE11 and RAD50 in human azoospermia patients. METHODS:Patients diagnosed with maturation arrest at the spermatocyte stage (MA) and Sertoli cell-only syndrome (SCOS) were recruited through diagnostic testicular biopsy. Patients with normal spermatogene...

journal_title：Journal of assisted reproduction and genetics

authors： Hu M,Li L,Liu S,Lou Y,Wang L,Le F,Li H,Wang Q,Lou H,Wang N,Jin F

更新日期：2020-02-01 00:00:00