abstract：BACKGROUND:Exposure to adversity is a risk factor for many mental and somatic health problems. Hypothalamic-pituitary-adrenal (HPA) axis dysregulation is a potential mechanism linking adversity exposure and negative health outcomes. However, associations between adversity exposure and HPA-axis activity have been incons...

journal_title：Psychoneuroendocrinology

authors： Oresta S,Vinkers CH,van Rossum EFC,Penninx BWJH,Nawijn L

更新日期：2021-01-20 00:00:00

abstract：:This study aimed to examine how loneliness contributes to metabolic dysregulation among older adults with depression and determine the relative contribution of loneliness to the development of chronic diseases in late adulthood. Harmonised data from the Ageing Trajectories of Health: Longitudinal Opportunities and Syn...

journal_title：Psychoneuroendocrinology

authors： de la Torre-Luque A,Lara E,de la Fuente J,Rico-Uribe LA,Caballero FF,Lopez-Garcia P,Sanchez-Niubo A,Bobak M,Koskinen S,Haro JM,Ayuso-Mateos JL

更新日期：2021-01-01 00:00:00

abstract：:In order to understand the psychopathology of the social anxiety disorder (SAD) at the neuroendocrine level, standardized experimental studies on endocrine and physiological markers are necessary, especially since empirical data are still ambiguous. Hence, differences in both, the autonomic nervous system (ANS) and th...

journal_title：Psychoneuroendocrinology

authors： Petrowski K,Schmalbach I,Strunk A,Hoyer J,Kirschbaum C,Joraschky P

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Family financial difficulties have been directly linked to poorer executive functioning in childhood. However, recent studies suggest that difficulties in affording basic items and other necessities may also indirectly affect children's executive functions through several psychological but also physiological...

journal_title：Psychoneuroendocrinology

authors： Kokosi T,Flouri E,Midouhas E

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Late life depression and perceived stress could influence disease pathways via reduced 11β-HSD2 activity, particularly given suggestions that reduced 11β-HSD2 activity, which is reflected in the cortisol-to-cortisone ratio, is a risk factor of disease. To date, however, examination of the relationship betwee...

journal_title：Psychoneuroendocrinology

authors： Shimanoe C,Matsumoto A,Hara M,Akao C,Nishida Y,Horita M,Nanri H,Higaki Y,Tanaka K

更新日期：2020-12-30 00:00:00

abstract：BACKGROUND:Optimism is linked with greater longevity in both White and African American populations. Optimism may enhance longevity by slowing cellular aging, for which leukocyte telomere shortening is a biomarker. However, limited studies have examined the association of optimism with leukocyte telomere length among A...

journal_title：Psychoneuroendocrinology

authors： Lee HH,Okuzono SS,Kim ES,De Vivo I,Raffield LM,Glover L,Sims M,Grodstein F,Kubzansky LD

更新日期：2020-12-29 00:00:00

abstract：BACKGROUND:Childhood adversity is a robust predictor of poor health outcomes in adulthood and hypothalamic-pituitary-adrenocortical (HPA) axis dysfunction may be a key mechanism explaining this association. However, little is known about the influence childhood adversity may exhibit on adult HPA axis habituation (i.e.,...

journal_title：Psychoneuroendocrinology

authors： Appelmann HM,Manigault AW,Shorey RC,Zoccola PM

更新日期：2020-12-24 00:00:00

abstract：:Glucocorticoid receptor (GR) antagonism is a promising new treatment for cognitive dysfunction in psychiatric disorders but the effects of GR antagonism on cognition related brain activity is poorly understood. This study examines the effects of the GR and progesterone receptor antagonist mifepristone on the neural co...

journal_title：Psychoneuroendocrinology

authors： Yalin N,Kempton MJ,Mazibuko N,Mehta MA,Young AH,Stokes PR

更新日期：2020-12-17 00:00:00

abstract：:Exposure to acute psychosocial stress has been shown to affect moral decision-making, though little is known about potential gender differences or effects of personality. In two within-subjects design studies, 179 healthy men and women (N = 99 in Study 1, N = 80 in Study 2) were exposed to the Trier Social Stress Test...

journal_title：Psychoneuroendocrinology

authors： Singer N,Sommer M,Wüst S,Kudielka BM

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Disturbances in the hypothalamic-pituitary-thyroid (HPT) and hypothalamic-pituitary-adrenal (HPA) axes have been frequently found in major depression. Given that glucocorticoids may inhibit thyrotropin (TSH) and thyrotropin-releasing hormone (TRH) secretion, it has been hypothesized that hypercortisolemia co...

journal_title：Psychoneuroendocrinology

authors： Mokrani MC,Duval F,Erb A,Gonzalez Lopera F,Danila V

更新日期：2020-12-01 00:00:00

abstract：AIMS:Mental health symptoms are frequent in women with gestational diabetes mellitus (GDM) and may influence glycemic control. We therefore investigated if mental health symptoms (high depression and low well-being scores) predicted a need for glucose-lowering medication and if this use of medication influenced the tra...

journal_title：Psychoneuroendocrinology

authors： Gilbert L,Nikolaou A,Quansah DY,Rossel JB,Horsch A,Puder JJ

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Emotion dysregulation can elicit inflammatory activity. The current study examined whether specific maladaptive and adaptive emotion regulation strategies were associated with inflammatory markers in trauma-exposed veterans, above and beyond PTSD. METHODS:In a cohort study, 606 participants exposed to a Cri...

journal_title：Psychoneuroendocrinology

authors： Khan AJ,O'Donovan A,Neylan TC,Gross JJ,Cohen BE

更新日期：2020-12-01 00:00:00

abstract：:Contagious stress describes the transmission of a stress response from a distressed individual (target) to an uninvolved observer. Building on social identity theory, we hypothesize that a shared social identity between the observer and the target as compared to a personal identity increases the likelihood of contagio...

journal_title：Psychoneuroendocrinology

authors： Schury VA,Nater UM,Häusser JA

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Cesarean delivery reduces the risk of infant and maternal morbidity and mortality when medically indicated, however, the cesarean delivery rate is estimated to be two to three times higher than medically necessary. The World Health Organization and American College of Obstetricians and Gynecologists have exp...

journal_title：Psychoneuroendocrinology

authors： Martinez LD,Glynn LM,Sandman CA,Wing DA,Davis EP

更新日期：2020-12-01 00:00:00

abstract：:Early adversity (EA) modulates stress hormone secretion in mixed directions. The Accumulation Model suggests that the number of EA predicts patterns of cortisol dysregulations, while the Life Cycle Model of Stress highlights the importance of considering the timing at which EA began, given that brain regions sensitive...

journal_title：Psychoneuroendocrinology

authors： Raymond C,Marin MF,Wolosianski V,Journault AA,Longpré C,Leclaire S,Cernik R,Juster RP,Lupien SJ

更新日期：2020-11-22 00:00:00

abstract：BACKGROUND:This report evaluated sex-specific differences in the association between brain aging and body mass index (BMI) in young adults using the publicly available data from the Human Connectome Project (HCP). METHODS:Participants of HCP with available structural imaging and BMI data were included [n = 1112; mean ...

journal_title：Psychoneuroendocrinology

authors： Chin Fatt CR,Jha MK,Minhajuddin A,Mayes T,Trivedi MH

更新日期：2020-11-16 00:00:00

abstract：:For the measurement of salivary alpha-amylase (sAA) activity, saliva samples first have to be diluted. There is some evidence for instability, that is, a decline of sAA activity in diluted samples. It is not clear which factors during dilution may contribute to this phenomenon and how quickly this decline of sAA activ...

journal_title：Psychoneuroendocrinology

authors： Skoluda N,Dhrami I,Nater UM

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis is implicated in the pathophysiology of post-traumatic stress disorder (PTSD). However, there has been little study of HPA stress reactivity in association with PTSD symptoms (PTSS) in children; and there is limited research on PTSD in low and mi...

journal_title：Psychoneuroendocrinology

authors： Zimmerman A,Halligan S,Skeen S,Morgan B,Fraser A,Fearon P,Tomlinson M

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Although the linkage between psychological stress and cortisol is believed to mediate the association of stress with health outcomes, several studies have been unable to demonstrate this association. We suggest this inability may be a consequence of limitations in the measurement approach and/or reliance on ...

journal_title：Psychoneuroendocrinology

authors： Lazarides C,Ward EB,Buss C,Chen WP,Voelkle MC,Gillen DL,Wadhwa PD,Entringer S

更新日期：2020-11-01 00:00:00

abstract：INTRODUCTION:Maternal early life maltreatment (ELM) and history of depression can bear a risk for adverse development in the child. One neurobiological pathway for the transmission of both maternal ELM and remitted depression (MDD) might be altered maternal cortisol levels. In the present study, we examine (1) main and...

journal_title：Psychoneuroendocrinology

authors： Kluczniok D,Bertsch K,Hindi Attar C,Neukel C,Fuchs A,Jaite C,Dittrich K,Bödeker K,Heinz A,Winter S,Brunner R,Herpertz SC,Bermpohl F

更新日期：2020-10-01 00:00:00

abstract：:Spouses share common risks for cardiometabolic diseases: a person's diabetes or hypertension raises the partner's odds of developing the same condition. The mechanisms responsible for this disease concordance remain poorly understood. To examine three factors that may modulate partners' cardiometabolic similarity-clos...

journal_title：Psychoneuroendocrinology

authors： Wilson SJ,Peng J,Andridge R,Jaremka LM,Fagundes CP,Malarkey WB,Belury MA,Kiecolt-Glaser JK

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND AND AIMS:The gut microbiota produces metabolites that are an integral part of the metabolome and, as such, of the host physiology. Changes in gut microbiota metabolism could therefore contribute to pathophysiological processes. We showed previously that a chronic and moderate overproduction of indole from tr...

journal_title：Psychoneuroendocrinology

authors： Mir HD,Milman A,Monnoye M,Douard V,Philippe C,Aubert A,Castanon N,Vancassel S,Guérineau NC,Naudon L,Rabot S

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:There is evidence that microRNA-195 (miR-195) is associated with schizophrenia (SZ) and cognition, but the relationship between miR-195 and cognitive impairment in SZ is still unknown. Sex differences in both microRNA (miRNA) expression and cognition were found in SZ. We aim to investigate whether sex moderat...

journal_title：Psychoneuroendocrinology

authors： Huang X,Bao C,Lv Q,Zhao J,Wang Y,Lang X,Li Z,Yi Z

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Previous studies have examined whether steroid hormone treatment in transgender individuals may affect cognitive function; yet, their limited power does not allow firm conclusions to be drawn. We leveraged data from to-date literature aiming to explore the effect of gender-affirming hormone administration on...

journal_title：Psychoneuroendocrinology

authors： Karalexi MA,Georgakis MK,Dimitriou NG,Vichos T,Katsimpris A,Petridou ET,Papadopoulos FC

更新日期：2020-09-01 00:00:00

abstract：:Cardiometabolic diseases are the main contributor of reduced life expectancy in patients with schizophrenia. It is now widely accepted that antipsychotic treatment plays an important role in the development of obesity and its consequences. However, some intrinsic mechanisms need to be taken into consideration. One of ...

journal_title：Psychoneuroendocrinology

authors： Lis M,Stańczykiewicz B,Liśkiewicz P,Misiak B

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Functional connectivity is a fundamental principle of brain organization. Cortisol, the end product of the hypothalamic-pituitary-adrenal axis, is a potent modulator of brain functions. Previous studies investigating the association between cortisol levels on brain connectivity are, however, limited to speci...

journal_title：Psychoneuroendocrinology

authors： Muehlhan M,Alexander N,Trautmann S,Weckesser LJ,Vogel S,Kirschbaum C,Miller R

更新日期：2020-07-01 00:00:00

abstract：:Social withdrawal may lead to mental health problems and can have a large impact on a life course, particularly among boys. To support adolescents with social withdrawal, an integrative understanding of the biological bases would be helpful. Social dominance, a possible opposite of social withdrawal, is known to have ...

journal_title：Psychoneuroendocrinology

authors： Hayashi N,Ando S,Jinde S,Fujikawa S,Okada N,Toriyama R,Masaoka M,Sugiyama H,Shirakawa T,Yagi T,Morita M,Morishima R,Kiyono T,Yamasaki S,Nishida A,Kasai K

更新日期：2020-06-01 00:00:00

abstract：:The purpose of this study was to explore whether individual differences in glucocorticoid concentrations were associated with symptom improvement following exposure therapy for patients with social anxiety disorder. To do this, 60 participants with social anxiety disorder completed a randomized-controlled trial of exp...

journal_title：Psychoneuroendocrinology

authors： Kuhlman KR,Treanor M,Imbriano G,Craske MG

更新日期：2020-06-01 00:00:00

abstract：OBJECTIVE:Glucocorticoid receptor gene (NR3C1) promoter methylation influences cellular expression of the glucocorticoid receptor and is a proposed mechanism by which early life stress impacts neuroendocrine function. Mitochondria are sensitive and responsive to neuroendocrine stress signaling through the glucocorticoi...

journal_title：Psychoneuroendocrinology

authors： Ridout KK,Coe JL,Parade SH,Marsit CJ,Kao HT,Porton B,Carpenter LL,Price LH,Tyrka AR

更新日期：2020-06-01 00:00:00

abstract：:Neighborhood violence is associated with a range of health consequences but little is known about the biological processes involved. Research in disease pathogenesis has identified low-grade inflammation as a process that, beginning in the first decades of life, is both induced by chronic stress and a contributor to m...

journal_title：Psychoneuroendocrinology

authors： Finegood ED,Chen E,Kish J,Vause K,Leigh AKK,Hoffer L,Miller GE

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVE:Prenatal stress (PS) contributes to depression-like behavior in the offspring. PDLIM5 is involved in the onset of mental disorders. This study is to investigate the role and mechanism of PDLIM5 in depression-like behavior of PS offspring rats. METHODS:PS model was used to analyze the effects of different tre...

journal_title：Psychoneuroendocrinology

authors： Lu Y,Jiang J,Si J,Wu Q,Tian F,Jiao K,Mu Y,Dong P,Zhu Z

更新日期：2020-05-01 00:00:00

abstract：INTRODUCTION:During pregnancy, maternal stressors cause changes in both maternal and fetal HPA axes. We therefore investigated the impact of maternal non chronic and chronic stress on fetal glucose metabolism and growth, and serum levels of cortisol in the fetus. MATERIALS AND METHODS:Normal weight pregnant women (n =...

journal_title：Psychoneuroendocrinology

authors： Valsamakis G,Papatheodorou D,Chalarakis N,Manolikaki M,Margeli A,Papassotiriou I,Barber TM,Kumar S,Kalantaridou S,Mastorakos G

更新日期：2020-04-01 00:00:00

abstract：:Stressors induce physiological changes in the brain and periphery that support adaptive defensive responses. The consequences of psychological stress on cognitive functioning are often measured in laboratory settings using experimentally induced stress that leads to mainly negative subjective feelings. There is a need...

journal_title：Psychoneuroendocrinology

authors： Everaerd DS,Henckens MJAG,Bloemendaal M,Bovy L,Kaldewaij R,Maas FMWM,Mulders PCR,Niermann HCM,van de Pavert I,Przezdzik I,Fernández G,Klumpers F,de Voogd LD

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Hair cortisol concentrations (HCC) are increasingly used as a biomarker of stress, however limited research exists regarding the relationship between HCC and protective factors, such as resilience. Additionally, studies measuring HCC need to account for possible confounders, and these factors have not been e...

journal_title：Psychoneuroendocrinology

authors： van den Heuvel LL,Acker D,du Plessis S,Stalder T,Suliman S,Thorne MY,Kirschbaum C,Seedat S

更新日期：2020-03-01 00:00:00

abstract：:Testosterone is associated with status-seeking behaviors such as competition, which may depend on whether one wins or loses status, but also on the stability of one's status. We examined (1) to what extent testosterone administration affects competition behavior in repeated social contests in men with high or low rank...

journal_title：Psychoneuroendocrinology

authors： Losecaat Vermeer AB,Krol I,Gausterer C,Wagner B,Eisenegger C,Lamm C

更新日期：2020-03-01 00:00:00

abstract：:Combined oral contraceptive (COC) use is associated with small, albeit significant, increases in mental symptom scores, predominantly irritability, depressed mood, and anxiety. Yet, randomized prospective trials are needed to better characterize the women at risk for COC-induced negative mood change. Thus, the primary...

journal_title：Psychoneuroendocrinology

authors： Scheuringer A,Lundin C,Derntl B,Pletzer B,Sundström Poromaa I

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVES:Exposure to adversity has been linked to accelerated biological aging, which in turn has been shown to predict numerous physical and mental health problems. In recent years, measures of DNA methylation-based epigenetic age--known as "epigenetic clocks"--have been used to estimate accelerated epigenetic aging...

journal_title：Psychoneuroendocrinology

authors： Marini S,Davis KA,Soare TW,Zhu Y,Suderman MJ,Simpkin AJ,Smith ADAC,Wolf EJ,Relton CL,Dunn EC

更新日期：2020-03-01 00:00:00

abstract：:Individuals who poorly regulate emotion exhibit premature aging and worse general health. Telomere shortening, a prognostic biomarker of physical health, is related to aging, poor immunocompetence and autonomic nervous system functioning. Cognitive reappraisal is one type of emotion regulation strategy, which involves...

journal_title：Psychoneuroendocrinology

authors： Shahane AD,LeRoy AS,Denny BT,Fagundes CP

更新日期：2020-02-01 00:00:00

abstract：:In mothers, offspring cues are associated with a powerful reinforcing value that motivates maternal care. Animal studies show that this is mediated by dopamine release into the nucleus accumbens, a core component of the brain's reward system located in the ventral striatum (VStr). The VStr is also known to respond to ...

journal_title：Psychoneuroendocrinology

authors： Hoekzema E,Tamnes CK,Berns P,Barba-Müller E,Pozzobon C,Picado M,Lucco F,Martínez-García M,Desco M,Ballesteros A,Crone EA,Vilarroya O,Carmona S

更新日期：2020-02-01 00:00:00

abstract：:Adolescent animals are vulnerable to the effects of stress on brain development. We hypothesized that long-term effects of adolescent chronic stress are mediated by glucocorticoid receptor (GR) signaling. We used a specific GR modulator (CORT108297) to pharmacologically disrupt GR signaling in adolescent rats during e...

journal_title：Psychoneuroendocrinology

authors： Cotella EM,Morano RL,Wulsin AC,Martelle SM,Lemen P,Fitzgerald M,Packard BA,Moloney RD,Herman JP

更新日期：2020-02-01 00:00:00