当前位置： SCI文献检索 > PSYCHONEUROENDOCRINOLOGY期刊下所有文献 > How childhood trauma and recent adverse events are related to hair cortisol levels in a large adult cohort.

How childhood trauma and recent adverse events are related to hair cortisol levels in a large adult cohort.

Abstract：

BACKGROUND:Exposure to adversity is a risk factor for many mental and somatic health problems. Hypothalamic-pituitary-adrenal (HPA) axis dysregulation is a potential mechanism linking adversity exposure and negative health outcomes. However, associations between adversity exposure and HPA-axis activity have been inconsistent. To understand the impact of adversity on the HPA-axis, we examined associations between early-life and recent adversity with hair cortisol concentration, an indicator of long-term systemic cortisol levels. METHODS:We included 1166 adult participants of the Netherlands Study of Depression and Anxiety (NESDA). Hair cortisol was measured in 3 cm of proximal hair, representing cortisol exposure during the previous 3 months. Childhood maltreatment, childhood negative life events, and recent negative life events were retrospectively assessed using interview and self-report questionnaires. Linear regression analyses were performed to assess the associations between childhood maltreatment, childhood life events and recent life events with hair cortisol. Associations with cumulative adversity exposure and with subtypes of childhood maltreatment, childhood and recent negative life events were also investigated, as were interaction effects between adversity and sex, age and psychopathology. RESULTS:Childhood maltreatment (β = 0.034, p = 0.243), childhood life events (β = - 0.017, p = 0.544), and recent life events (β = - 0.021, p = 0.456) were not significantly associated with hair cortisol levels. Subtypes of childhood maltreatment and specific childhood and recent life events were not significantly associated with hair cortisol (pFDR>0.05). There were no significant interaction effects between adversity exposure and sex, age or depression/anxiety diagnostic status on hair cortisol. CONCLUSIONS:There were no significant associations between childhood and recent adversity with systemic cortisol levels in adults. Effects of early-life and adult adversity are complex and may not directly impact on long-term systemic cortisol levels as measured in hair.

journal_name

Psychoneuroendocrinology

journal_title

Psychoneuroendocrinology

authors

Oresta S,Vinkers CH,van Rossum EFC,Penninx BWJH,Nawijn L

doi

10.1016/j.psyneuen.2021.105150

subject

Has Abstract

pub_date

2021-01-20 00:00:00

pages

105150

eissn

0306-4530

issn

1873-3360

pii

S0306-4530(21)00024-X

journal_volume

126

pub_type

杂志文章

相关文献

PSYCHONEUROENDOCRINOLOGY文献大全
  • Synaptic functions in the aged rat hippocampus: a target for corticosteroids?

    abstract：:The role of corticosteroids in brain aging remains a controversial issue. Conceivably, if corticosteroids levels are increased in the aged brain, neuronal function might be altered. For instance, GABA-mediated synaptic events, spike accommodation and afterhyperpolarizing potentials (AHPs) might be modified. Our electr...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/s0306-4530(97)00008-5

    authors： Lamour Y,Potier B,Jouvenceau A,Billard JM,Dutar P

    更新日期：1997-01-01 00:00:00

  • The stress hormone cortisol blocks perceptual learning in humans.

    abstract：:Cortisol, the primary glucocorticoid (GC) in humans, influences neuronal excitability and plasticity by acting on mineralocorticoid and glucocorticoid receptors. Cellular studies demonstrated that elevated GC levels affect neuronal plasticity, for example through a reduction of hippocampal long-term potentiation (LTP)...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.psyneuen.2016.12.002

    authors： Dinse HR,Kattenstroth JC,Lenz M,Tegenthoff M,Wolf OT

    更新日期：2017-03-01 00:00:00

  • The physiological response to Trier Social Stress Test relates to subjective measures of stress during but not before or after the test.

    abstract：:The Trier Social Stress Test (TSST) is an effective psychosocial laboratory protocol for inducing stress in humans and has been used in numerous research studies. The stressor leads to a physiological response of the hypothalamus-pituitary-adrenal axis (HPAA) and the autonomous nervous system (ANS). Common biomarkers ...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2011.05.012

    authors： Hellhammer J,Schubert M

    更新日期：2012-01-01 00:00:00

  • Contribution of norepinephrine to emotional memory consolidation during sleep.

    abstract：BACKGROUND:There is increasing evidence indicating that slow wave sleep (SWS) supports memory consolidation. This effect may in part originate from phasic noradrinergic (NE) activity occurring during SWS in the presence of tonically lowered NE levels. Here, we examined whether NE supports the consolidation of amygdala-...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.psyneuen.2011.03.006

    authors： Groch S,Wilhelm I,Diekelmann S,Sayk F,Gais S,Born J

    更新日期：2011-10-01 00:00:00

  • Cognitive effects and antipsychotic treatment.

    abstract：:Cognitive impairment has long been recognized as central to the abnormalities that occur in schizophrenia, since neurocognitive deficits are predictive of a number of outcome indices, and they pose a significant obstacle to any attempts at social rehabilitation. This raises the possibility that treatments producing im...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章,评审

    doi：10.1016/s0306-4530(02)00115-4

    authors： Kasper S,Resinger E

    更新日期：2003-01-01 00:00:00

  • Expression of tumor necrosis factor-alpha and interferon-gamma mRNA in blood cells correlates with depression scores during an acute attack in patients with multiple sclerosis.

    abstract：:Depression is a common problem in multiple sclerosis (MS) and affects about 50% of MS patients. Since a dysregulation of cytokine levels has been implicated in the pathogenesis of MS and alterations in cytokine serum levels have been found in depressive illness, we examined the relationship between depressive symptoms...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/s0306-4530(01)00068-3

    authors： Kahl KG,Kruse N,Faller H,Weiss H,Rieckmann P

    更新日期：2002-08-01 00:00:00

  • Extinction of fear is facilitated by social presence: Synergism with prefrontal oxytocin.

    abstract：:This study addressed the question of whether extinction in pairs would have a beneficial effect on extinction of fear conditioning. To that end, we established an experimental setting for extinction in which we trained animals to extinguish contextual fear memory in pairs. Taking advantage of the role of oxytocin (OT)...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2016.01.003

    authors： Brill-Maoz N,Maroun M

    更新日期：2016-04-01 00:00:00

  • Selective lentiviral-mediated suppression of microRNA124a in the hippocampus evokes antidepressants-like effects in rats.

    abstract：:Several lines of evidences suggest that the brain-derived neutrophic factor (BDNF) is implicated in the pathophysiology of depression. However, the molecular mechanisms are not fully understood. In the current study we aimed to investigate how genetic modulation of BDNF in the hippocampus using microRNa124a (miR124a)-...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2014.04.009

    authors： Bahi A,Chandrasekar V,Dreyer JL

    更新日期：2014-08-01 00:00:00

  • Stress, serotonergic function, and mood in users of oral contraceptives.

    abstract：:The relationship between stress and changes in insulin levels, plasma ratio of tryptophan to other large neutral amino acids (LNAAs), mood, and food intake was investigated in women taking monophasic oral contraceptives containing progestagens. Subjects experiencing high levels of stress displayed significant decrease...

    journal_title：Psychoneuroendocrinology

    pub_type： 临床试验,杂志文章

    doi：10.1016/0306-4530(94)00063-g

    authors： Tuiten A,Panhuysen G,Koppeschaar H,Fekkes D,Pijl H,Frölich M,Krabbe P,Everaerd W

    更新日期：1995-01-01 00:00:00

  • Cerebrospinal fluid and plasma testosterone levels in post-traumatic stress disorder and tobacco dependence.

    abstract：BACKGROUND:Little is known about the relationship between endogenous central nervous system (CNS) testosterone and any psychiatric syndrome. The goal of this study was to screen for potential abnormalities in CNS testosterone levels in patients with post-traumatic stress disorder (PTSD) and/or tobacco dependence. METH...

    journal_title：Psychoneuroendocrinology

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0306-4530(00)00052-4

    authors： Mulchahey JJ,Ekhator NN,Zhang H,Kasckow JW,Baker DG,Geracioti TD Jr

    更新日期：2001-04-01 00:00:00

  • T4 and waist:hip ratio as biomarkers of antipsychotic-induced weight gain in Han Chinese inpatients with schizophrenia.

    abstract：:Second-generation antipsychotic agents (SGAs) cause serious metabolic side effects, including weight gain, dyslipidemia, and glucose metabolism abnormalities, which occur by unknown mechanisms. Therefore, the search for prospective markers for antipsychotic-induced weight gain (AIWG) has been of major interest. So far...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2017.11.010

    authors： Li S,Gao Y,Lv H,Zhang M,Wang L,Jiang R,Xu C,Wang X,Gao M,He Y,Li J,Li WD

    更新日期：2018-02-01 00:00:00

  • Emerging role of the P2X7-NLRP3-IL1β pathway in mood disorders.

    abstract：:The science of neuroimmunopsychiatry has evolved rapidly in the last few years with the hope of tackling the unmet need in mood disorders. This article focuses on an inflammatory pathway, highly conserved in myeloid cells that may play a role in neuroinflammatory disorders including depression. Within the brain tissue...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章,评审

    doi：10.1016/j.psyneuen.2018.08.015

    authors： Bhattacharya A,Jones DNC

    更新日期：2018-12-01 00:00:00

  • Effects of change of mothers and lighting conditions on the development of the circadian adrenocortical rhythm in blinded rat pups.

    abstract：:Free-running blood corticosterone rhythms were examined between the 4th and 9th postnatal week in blinded rat pups optically enucleated on day 1. The pups were born of mother rats having a free-running rhythm under constant illumination conditions and then were put under two separate illumination conditions (light - d...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/0306-4530(83)90060-4

    authors： Yamazaki J,Takahashi K

    更新日期：1983-01-01 00:00:00

  • Dipeptidyl peptidase- IV inhibitor alogliptin improves stress-induced insulin resistance and prothrombotic state in a murine model.

    abstract：BACKGROUND:Stress evokes lipolytic release of free fatty acid (FFA) and low-grade inflammation in visceral adipose tissue, mediated by increased adipokine secretion, and contributes to glucose metabolism disorder and prothrombotic state. We tested the hypothesis that alogliptin, a dipeptidyl peptidase-4 inhibitor, can ...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2016.08.004

    authors： Yisireyili M,Takeshita K,Hayashi M,Wu H,Uchida Y,Yamamoto K,Kikuchi R,Hao CN,Nakayama T,Cheng XW,Matsushita T,Nakamura S,Murohara T

    更新日期：2016-11-01 00:00:00

  • Childhood urbanicity and hair steroid hormone levels in ten-year-old children.

    abstract：BACKGROUND:Research suggests that it may be more stressful for children to grow up in an urban area than in a rural area. Urbanicity may affect physiological stress system functioning as well as the timing of sexual maturation. The purpose of the current study was to investigate whether moderate urbanicity (current and...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2018.11.039

    authors： Evans BE,Beijers R,Hagquist C,de Weerth C

    更新日期：2019-04-01 00:00:00

  • Linking genetic variants of the mineralocorticoid receptor and negative memory bias: interaction with prior life adversity.

    abstract：:Substantial research has been conducted investigating the association between life adversity and genetic vulnerability for depression, but clear mechanistic links are rarely identified and investigation often focused on single genetic variants. Complex phenotypes like depression, however, are likely determined by mult...

    journal_title：Psychoneuroendocrinology

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.psyneuen.2013.11.010

    authors： Vogel S,Gerritsen L,van Oostrom I,Arias-Vásquez A,Rijpkema M,Joëls M,Franke B,Tendolkar I,Fernández G

    更新日期：2014-02-01 00:00:00

  • Chronic stress differentially regulates glucocorticoid negative feedback response in rats.

    abstract：:Exposure to chronic stress is thought to play an important role in the etiology of depression. In this disorder, a disrupted negative feedback response to exogenous glucocorticoids on cortisol secretion has been indicated. However, the regulation of glucocorticoid negative feedback by chronic stress is not fully under...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/s0306-4530(01)00004-x

    authors： Mizoguchi K,Yuzurihara M,Ishige A,Sasaki H,Chui DH,Tabira T

    更新日期：2001-07-01 00:00:00

  • The glucocorticoid receptor antagonist mifepristone reduces ethanol intake in rats under limited access conditions.

    abstract：:There is a substantial amount of evidence indicating control over ethanol intake by steroid hormones, particularly adrenal glucocorticoids. Thus far, however, studies employing pharmacological methods have failed to find effects of glucocorticoid receptor blockade on voluntary ethanol consumption. Since length of etha...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2003.09.004

    authors： Koenig HN,Olive MF

    更新日期：2004-09-01 00:00:00

  • Pregnancy, the postpartum, and steroid hormones: effects on cognition and mood.

    abstract：:The effects of pregnancy on cognition and mood were examined using a repeated-measures design. Nineteen women, average age 33, were tested with a comprehensive neuropsychological battery during their last 2 months of pregnancy and again within 2 months of delivery. Blood samples were obtained from all subjects and ass...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/s0306-4530(98)00044-4

    authors： Buckwalter JG,Stanczyk FZ,McCleary CA,Bluestein BW,Buckwalter DK,Rankin KP,Chang L,Goodwin TM

    更新日期：1999-01-01 00:00:00

  • Corticotropin-releasing factor (CRF): stimulation in normal controls and in patients with Cushing's syndrome.

    abstract：:Synthetic ovine and human CRF were given as an i.v. bolus to six healthy volunteers in four and two different dosages, respectively (oCRF: 25, 50, 100 and 200 micrograms; hCRF: 50 and 100 micrograms). There was a significant increase of ACTH and cortisol after the injection of all dosages though the dose-response rela...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/0306-4530(86)90031-4

    authors： Müller OA,Hartwimmer J,Hauer A,Kaliebe T,Schopohl J,Stalla GK,von Werder K

    更新日期：1986-01-01 00:00:00

  • Differential effects of the 18-kDa translocator protein (TSPO) ligand etifoxine on steroidogenesis in rat brain, plasma and steroidogenic glands: Pharmacodynamic studies.

    abstract：:Etifoxine is indicated in humans for treating anxiety. In rodents, besides its anxiolytic-like properties, it has recently shown neuroprotective and neuroregenerative activities. It acts by enhancing GABAA receptor function and by stimulating acute steroid biosynthesis via the activation of the 18-kDa translocator pro...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2017.05.022

    authors： Liere P,Pianos A,Oudinet JP,Schumacher M,Akwa Y

    更新日期：2017-09-01 00:00:00

  • Relationship between testosterone supplementation and insulin-like growth factor-I levels and cognition in healthy older men.

    abstract：BACKGROUND:Our laboratory has previously reported that testosterone (T) administration to older men significantly improves cognitive function. This study examined potential changes in insulin-like growth factor (IGF) IGF-I, IGF-II and IGF-related binding proteins in response to T administration in older men and their r...

    journal_title：Psychoneuroendocrinology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0306-4530(02)00136-1

    authors： Cherrier MM,Plymate S,Mohan S,Asthana S,Matsumoto AM,Bremner W,Peskind E,Raskind M,Latendresse S,Haley AP,Craft S

    更新日期：2004-01-01 00:00:00

  • Microglial-driven changes in synaptic plasticity: A possible role in major depressive disorder.

    abstract：:Recent data gathered from both in vitro and in vivo models of Major Depressive Disorder (MDD) have indicated that microglia play an active role in modifying some of the most important sources for neuronal plasticity, specifically long-term potentiation (LTP) and long-term depression (LTD). In addition, microglia have ...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章,评审

    doi：10.1016/j.psyneuen.2018.12.233

    authors： Innes S,Pariante CM,Borsini A

    更新日期：2019-04-01 00:00:00

  • Environmental enrichment models a naturalistic form of maternal separation and shapes the anxiety response patterns of offspring.

    abstract：:Environmental enrichment (EE) mimics positive life experiences by providing enhanced social and physical stimulation. Placement into EE following weaning, or in later life, confers beneficial outcomes on both emotional and cognitive processes. However, anxiety-like behavior is also reported, particularly in rats expos...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2014.10.021

    authors： Connors EJ,Migliore MM,Pillsbury SL,Shaik AN,Kentner AC

    更新日期：2015-02-01 00:00:00

  • Isoallopregnanolone antagonize allopregnanolone-induced effects on saccadic eye velocity and self-reported sedation in humans.

    abstract：:Allopregnanolone (AP) is an endogenous neurosteroid. It modulates the effect of γ-amino-butyric acid (GABA) on the GABA type A (GABAA) receptor, which leads to increased receptor activity. Since the GABA-system is mainly inhibitory, increased AP activity leads to modulation of neuronal activity. In vitro studies of GA...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.psyneuen.2014.10.025

    authors： Bengtsson SK,Nyberg S,Hedström H,Zingmark E,Jonsson B,Bäckström T,Bixo M

    更新日期：2015-02-01 00:00:00

  • Prenatal and postnatal cortisol and testosterone are related to parental caregiving quality in fathers, but not in mothers.

    abstract：:Testosterone and cortisol have both been implicated in human parenting behavior. We investigated the relations between observed quality of caregiving during parent-child interactions and pre- and postnatal testosterone and cortisol levels, in both mothers (N = 88) and fathers (N = 57). Testosterone and cortisol were m...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2018.07.013

    authors： Bos PA,Hechler C,Beijers R,Shinohara K,Esposito G,de Weerth C

    更新日期：2018-11-01 00:00:00

  • High cortisol awakening response in the aftermath of workplace violence exposure moderates the association between acute stress disorder symptoms and PTSD symptoms.

    abstract：:Although a majority of people will be exposed to a traumatic event over the course of their lifespan, only a minority will develop post-traumatic stress disorder. Better understanding the factors contributing to the development of this psychopathology is of high importance and could significantly reduce the societal a...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2019.03.006

    authors： Marin MF,Geoffrion S,Juster RP,Giguère CE,Marchand A,Lupien SJ,Guay S

    更新日期：2019-06-01 00:00:00

  • HPA axis activation by a socially evaluated cold-pressor test.

    abstract：:The cold-pressor test (CPT) in which subjects immerse their hand in ice water is among the most commonly used laboratory stressors. While the CPT elicits strong sympathetic nervous system activation, cortisol elevations indicative for the reactivity of the hypothalamus-pituitary-adrenal (HPA) axis are moderate to low ...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.psyneuen.2008.03.001

    authors： Schwabe L,Haddad L,Schachinger H

    更新日期：2008-07-01 00:00:00

  • Thyroid stimulating hormone, free thyroxine and cognitive ability in old age: the Lothian Birth Cohort Study 1936.

    abstract：:The current study investigated the associations between thyroid stimulating hormone (TSH), free thyroxine (T(4)) and cognitive ability (general ability, memory and processing speed), in a large age homogenous sample (n=659) of generally healthy euthyroid older adults. Associations were considered both at baseline (mea...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2012.07.018

    authors： Booth T,Deary IJ,Starr JM

    更新日期：2013-04-01 00:00:00

  • Chronic intermittent cold stress sensitizes neuro-immune reactivity in the rat brain.

    abstract：:Chronic stress contributes to many neuropsychiatric disorders in which the HPA axis, cognition and neuro-immune activity are dysregulated. Patients with major depression, or healthy individuals subjected to acute stress, present elevated levels of circulating pro-inflammatory markers. Acute stress also activates pro-i...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2011.02.008

    authors： Girotti M,Donegan JJ,Morilak DA

    更新日期：2011-09-01 00:00:00