abstract：:Polycystic ovarian syndrome (PCOS) presents as a constellation of clinical manifestations that can be varied among patients; however, the hormonal derangement associated with PCOS is uniformly characterized by excess androgens and abnormal insulin activity. The alteration in the normal hormonal milieu in these patient...

journal_title：Clinical obstetrics and gynecology

authors： Lindner PG

更新日期：2021-03-01 00:00:00

abstract：:Cardiac disease is a leading cause of morbidity and mortality in pregnant women. An increased prevalence of the cardiovascular disease has been found in women of childbearing age, in which the responsibility of the treating physician extends to the mother and to the unborn fetus. As a result, care of these high-risk p...

journal_title：Clinical obstetrics and gynecology

authors： Chan A,Wolfe DS,Zaidi AN

更新日期：2020-12-01 00:00:00

abstract：:Intrahepatic cholestasis of pregnancy is a common disorder of pregnancy manifested by pruritus and elevated bile acids. The etiology of cholestasis is poorly understood and management is difficult due to the paucity of data regarding its diagnosis, treatment, and related adverse outcomes. In this article, we review th...

journal_title：Clinical obstetrics and gynecology

authors： Smith DD,Rood KM

更新日期：2020-03-01 00:00:00

abstract：:Some of the patients with epithelial ovarian cancer will not respond to initial therapy. These patients have a poor prognosis. Our aim was to identify patients with a worse prognosis by integrating clinical, pathologic, and genomic data. Using publicly available genomic data and integrating it with clinical data, we s...

journal_title：Clinical obstetrics and gynecology

authors： Newtson AM,Devor EJ,Gonzalez Bosquet J

更新日期：2020-03-01 00:00:00

abstract：:In our proof-of-concept study of 1 patient with stage IIIC carcinosarcoma of the ovary, we discovered a rare mutation in the tumor suppressor, TP53, that results in the deletion of N131. Immunofluorescence imaging of the organoid culture revealed hyperstaining of p53 protein. Computational modeling suggests this resid...

journal_title：Clinical obstetrics and gynecology

authors： Bi J,Thiel KW,Litman JM,Zhang Y,Devor EJ,Newtson AM,Schnieders MJ,Gonzalez Bosquet J,Leslie KK

更新日期：2020-03-01 00:00:00

abstract：:Chronic pelvic is a multifaceted condition that often has both peripheral and central generators of pain. Despite its high prevalence, the evaluation and management of a pelvic pain patient often present many challenges to the practicing gynecologist. As with many other chronic pain conditions, pain severity does not ...

journal_title：Clinical obstetrics and gynecology

authors： Carey ET,Moore K

更新日期：2019-12-01 00:00:00

abstract：:This article will review the basic principles of risk management, the role of the risk manager, and the importance of risk management in the patient safety movement as it pertains to obstetrics and gynecology. Several tools that are used by risk managers including risk assessments and root cause analyses will be used ...

journal_title：Clinical obstetrics and gynecology

authors： Klein VR

更新日期：2019-09-01 00:00:00

abstract：:In the last 10 years, expanded preconception carrier screening has become widely available and helps patients/couples make more informed decisions with regard to their reproductive options and facilitates more effective preconception planning, prenatal diagnosis, condition-specific counseling, and condition-specific c...

journal_title：Clinical obstetrics and gynecology

authors： Zhang T,Madeira J,Lu Y,Sun Y,Mertes H,Pennings G,Lindheim SR

更新日期：2019-06-01 00:00:00

abstract：:Hyperthyroidism is relatively uncommon during pregnancy. However, those caring for pregnant patients should be versed in the evaluation and management of hyperthyroidism, as there are potential maternal and fetal implications that are related to the disease and to treatment. The differential diagnosis of hyperthyroidi...

journal_title：Clinical obstetrics and gynecology

authors： Cuff RD

更新日期：2019-06-01 00:00:00

abstract：:Predelivery diagnosis of placenta accreta, increta, and percreta (from here referred to as placenta accreta, unless otherwise noted) has increasingly created opportunities to optimize antenatal management. Despite the increased frequency of placenta accreta today, occurring in as many as 1 in 533 to 1 in 272 deliverie...

journal_title：Clinical obstetrics and gynecology

authors： Haunschild C,Yeaton-Massey A,Lyell DJ

更新日期：2018-12-01 00:00:00

abstract：:The purpose of this review was to assist obstetricians and gynecologists in considering the most appropriate conservative treatment option to manage women with placenta accreta spectrum according to their individual need and local expertise of the heath care team. The issue is challenging, as the quality of evidence w...

journal_title：Clinical obstetrics and gynecology

authors： Sentilhes L,Kayem G,Silver RM

更新日期：2018-12-01 00:00:00

abstract：:The provision of hormone therapy, both estrogens and antiandrogens, to adult transgender females is well within the scope of practice of the obstetrician gynecologist. The goal is to induce feminizing changes and suppress previously developed masculinization. Estrogens in sufficient doses will usually achieve both goa...

journal_title：Clinical obstetrics and gynecology

authors： Randolph JF Jr

更新日期：2018-12-01 00:00:00

abstract：:The role of Interventional radiologic procedures for the management of suspected placenta accreta spectrum (PAS) has evolved considerably over last 3 decades. In this article, the authors describe the various techniques of vascular occlusion for the management of PAS and provide a brief review of the literature examin...

journal_title：Clinical obstetrics and gynecology

authors： Shrivastava VK,Nageotte MP

更新日期：2018-12-01 00:00:00

abstract：:Current findings continue to support the concept of a biologically defective decidua rather than a primarily abnormally invasive trophoblast. Prior cesarean sections increase the risk of placenta previa and both adherent and invasive placenta accreta, suggesting that the endometrial/decidual defect following the iatro...

journal_title：Clinical obstetrics and gynecology

authors： Jauniaux E,Burton GJ

更新日期：2018-12-01 00:00:00

abstract：:Genitourinary syndrome of menopause (GSM) describes a collection of exam findings and bothersome symptoms associated with estrogen deficiency involving changes to the labia, introitus, clitoris, vagina, urethra, and bladder. Vulvovaginal atrophy is a component of GSM. GSM is a highly prevalent medical condition with a...

journal_title：Clinical obstetrics and gynecology

authors： Shifren JL

更新日期：2018-09-01 00:00:00

abstract：:The UK Confidential Enquiry into Maternal Deaths has been in operation for more than 60 years, during which time maternal mortality rates have fallen 10-fold. The program includes two aspects, surveillance and confidential case review, providing different information to aid quality improvement in maternity care. The e...

journal_title：Clinical obstetrics and gynecology

authors： Knight M,Tuffnell D

更新日期：2018-06-01 00:00:00

abstract：:State Perinatal Quality Collaboratives (PQCs) represent a major advance for scaling up quality improvement efforts for reducing maternal mortality and severe maternal morbidity. The critical roles of partners, rapid-cycle low-burden data systems, and linkage to maternal mortality review committees are reviewed. The ch...

journal_title：Clinical obstetrics and gynecology

authors： Main EK

更新日期：2018-06-01 00:00:00

abstract：:Stroke risk is 3 times higher in pregnancy than in the general young adult population and carries high morbidity and mortality risks. The recognition of signs and symptoms of stroke and other serious cerebrovascular disorders in pregnant and postpartum patients is important for the obstetrician to be able to initiate ...

journal_title：Clinical obstetrics and gynecology

authors： Barghouthi T,Bushnell C

更新日期：2018-06-01 00:00:00

abstract：:This article reviews the sonographic manifestations of fetal infection and the role of ultrasound in the evaluation of the fetus at risk for congenital infection. Several ultrasound findings have been associated with in utero fetal infections. For the patient with a known or suspected fetal infection, sonographic iden...

journal_title：Clinical obstetrics and gynecology

authors： Crino JP,Driggers RW

更新日期：2018-03-01 00:00:00

abstract：:Serous tubal intraepithelial carcinoma is considered the precursor lesion of high-grade serous carcinoma, and found in both low-risk and high-risk populations. Isolated serous tubal intraepithelial carcinomas in patients with BRCA1/2 mutations are detected in ∼2% of patients undergoing risk-reducing bilateral salpingo...

journal_title：Clinical obstetrics and gynecology

authors： Patrono MG,Corzo C,Iniesta M,Ramirez PT

更新日期：2017-12-01 00:00:00

abstract：:Endometriosis is a chronic medical condition that affects around 6% to 10% of reproductive age women. Pelvic pain, dysmenorrhea, and infertility are the most common presenting symptoms. The disease is characterized by estrogen-dependent growth of the endometrial glands and stroma outside the endometrial cavity. The di...

journal_title：Clinical obstetrics and gynecology

authors： Rafique S,Decherney AH

更新日期：2017-09-01 00:00:00

abstract：:Care of the endometriosis patient today can be complex and difficult. Once medical management has been exhausted and symptoms persist patients desire further treatment options. This chapter takes an evidence-based approach at discussion of patient surgcical options for treatment of endometriosis symptoms. Surgical tec...

journal_title：Clinical obstetrics and gynecology

authors： Zanelotti A,Decherney AH

更新日期：2017-09-01 00:00:00

abstract：:Pregnancy failure is defined as a lack of sonographic evidence of current or expected viability. Technologic advances in ultrasound imaging continue to redefine diagnostic criteria of pregnancy failure or success. When evaluating a pregnancy, the first step is an assessment of maternal risk factors for failure. Imagin...

journal_title：Clinical obstetrics and gynecology

authors： Canavan TP

更新日期：2017-09-01 00:00:00

abstract：:Once the decision to perform a hysterectomy has been made, the type and route of hysterectomy must be chosen, and efforts made to accomplish the surgery as safely as possible. Hysterectomy can be performed vaginally, abdominally with laparoscopic or robotic assistance, or open. The main goal of gynecologic surgeons sh...

journal_title：Clinical obstetrics and gynecology

authors： Walters MD,Ridgeway BM

更新日期：2017-06-01 00:00:00

abstract：:Minimally invasive surgery continues to transform the field of gynecologic oncology and has now become the standard of care for many early-stage malignancies. The proven benefits of minimally invasive surgery are driving the rapid introduction and dissemination of novel technologies and the increasing ability to perfo...

journal_title：Clinical obstetrics and gynecology

authors： Stewart KI,Fader AN

更新日期：2017-06-01 00:00:00

abstract：:During the past decade, prophylactic doses of low-molecular-weight heparin (LMWH) have been suggested to decrease the risk of placental-mediated complications. Herein, we review the prospective randomized trials that addressed the usefulness of LMWH in preventing placental-mediated complications in high-risk women. In...

journal_title：Clinical obstetrics and gynecology

authors： Haddad B,Lecarpentier E,Touboul C,Sibai BM

更新日期：2017-03-01 00:00:00

abstract：:Despite advances in estimating prognosis and predicting response to adjuvant systemic therapy, the status of the axillary lymph nodes remains a critical component in initial surgical planning and in determining therapeutic strategies for patients with breast cancer. Buoyed by evidence from multi-institutional randomiz...

journal_title：Clinical obstetrics and gynecology

authors： McCARTAN D,Gemignani ML

更新日期：2016-12-01 00:00:00

abstract：:Shoulder dystocia complicates ∼1% of vaginal births. Although fetal macrosomia and maternal diabetes are risk factors for shoulder dystocia, for the most part its occurrence remains largely unpredictable and unpreventable. ...

journal_title：Clinical obstetrics and gynecology

authors： Ouzounian JG

更新日期：2016-12-01 00:00:00

abstract：:There has been a steady decline in breast cancer mortality that has led to a significant increase in the number of patients surviving breast cancer. We will review in this manuscript the evidence and guidelines for posttreatment surveillance of patients with breast cancer as well as the management options for patients...

journal_title：Clinical obstetrics and gynecology

authors： Karam AK

更新日期：2016-12-01 00:00:00

abstract：:In recent years it has been recognized that in all phases of life, including pregnancy, physical activity promotes health benefits and precludes comorbidities, the scientific evidence is indisputable. Several organizations around the world have updated in recent years the guidelines and recommendations for exercise in...

journal_title：Clinical obstetrics and gynecology

authors： Artal R

更新日期：2016-09-01 00:00:00

abstract：:Prevention of spontaneous preterm birth is an important public health priority. Pessary may be a potential therapy in cases of cervical insufficiency, in singleton and multiple gestations. Availability of transvaginal sonography for accurate assessment of cervical length is allowing for the tailoring of therapy to a m...

journal_title：Clinical obstetrics and gynecology

authors： Timofeev J

更新日期：2016-06-01 00:00:00

abstract：:Cervical cerclage is a surgical procedure to prevent preterm birth. There are currently 3 main indications, based on either history, ultrasound, or physical exam changes. ...

journal_title：Clinical obstetrics and gynecology

authors： Roman A,Suhag A,Berghella V

更新日期：2016-06-01 00:00:00

abstract：:The utility and effectiveness of screening mammography in diagnosing breast cancer at earlier stages and reducing disease-specific mortality remain controversial especially as to when to start and stop routine mammographic screening, and whether mammograms should be performed annually or biennially in average-risk wom...

journal_title：Clinical obstetrics and gynecology

authors： Swain M,Jeudy M,Pearlman MD

更新日期：2016-06-01 00:00:00

abstract：:In the United States, roughly half of women are either overweight (24.5%) or obese (21.4%) when they become pregnant. Women who are obese before pregnancy are at increased risk for a number of pregnancy complications relative to normal-weight women. Specifically, obesity is associated with significantly increased mate...

journal_title：Clinical obstetrics and gynecology

authors： Simhan HN

更新日期：2016-03-01 00:00:00

abstract：:In mammalian reproductive physiology, lactation follows pregnancy; growing evidence suggests that disruption of this physiology affects a woman's lifetime risk of metabolic disease. These differences may reflect lactation-induced mobilization of fat stores and modulation of maternal stress reactivity. In addition, con...

journal_title：Clinical obstetrics and gynecology

authors： Stuebe A

更新日期：2015-12-01 00:00:00

abstract：:Endometriomas are common in reproductive-aged women, but controversy exists regarding their management. PubMed was searched to identify pertinent studies on outcomes of medical and surgical management of endometrioma, with focus on randomized controlled trials and meta-analyses. Surgical excision is more effective tha...

journal_title：Clinical obstetrics and gynecology

authors： Johnstone EB,Link MH

更新日期：2015-12-01 00:00:00

abstract：:The appearance of the female external genitalia is key for understanding and diagnosing many diseases that women of all ages encounter. Alas, the normal appearance of the vulva is an elusive concept, scarcely represented in textbooks, and the growing number of vulvar cosmetic surgery calls for a review of the normal a...

journal_title：Clinical obstetrics and gynecology

authors： Cohen Sacher B

更新日期：2015-09-01 00:00:00

abstract：:The purpose of this paper is to assist the clinician in recognizing pelvic floor muscle dysfunction in women with vulvar symptoms, to provide general treatment algorithms, and to facilitate understanding of the scientific rationale behind appropriate treatment. In short, this paper is meant to provide a "how-to" guide...

journal_title：Clinical obstetrics and gynecology

authors： Albrecht KB

更新日期：2015-09-01 00:00:00

abstract：:Higher-order multiple gestations have increased since the advent of advanced reproductive technologies. These pregnancies present unique risks to both mothers and fetuses. It is imperative that early diagnosis of chronicity be determined and that proper counseling is performed, so patients understand the risks, evalua...

journal_title：Clinical obstetrics and gynecology

authors： Stone J,Kohari KS

更新日期：2015-09-01 00:00:00

abstract：:Pregnancy is an opportune time to identify opioid dependence, facilitate conversion to opioid maintenance treatment, and coordinate care with specialists in addiction medicine, behavioral health, and social services. Comprehensive prenatal care for opioid-dependent women involves the evaluation and the management of c...

journal_title：Clinical obstetrics and gynecology

authors： Krans EE,Cochran G,Bogen DL

更新日期：2015-06-01 00:00:00