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  • Long-term Health of Offspring of Women With Polycystic Ovarian Syndrome.

    abstract::Polycystic ovarian syndrome (PCOS) presents as a constellation of clinical manifestations that can be varied among patients; however, the hormonal derangement associated with PCOS is uniformly characterized by excess androgens and abnormal insulin activity. The alteration in the normal hormonal milieu in these patient...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/GRF.0000000000000598

    authors: Lindner PG

    更新日期:2021-03-01 00:00:00

  • Pregnancy and Congenital Heart Disease: A Brief Review of Risk Assessment and Management.

    abstract::Cardiac disease is a leading cause of morbidity and mortality in pregnant women. An increased prevalence of the cardiovascular disease has been found in women of childbearing age, in which the responsibility of the treating physician extends to the mother and to the unborn fetus. As a result, care of these high-risk p...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/GRF.0000000000000579

    authors: Chan A,Wolfe DS,Zaidi AN

    更新日期:2020-12-01 00:00:00

  • Prediction of Epithelial Ovarian Cancer Outcomes With Integration of Genomic Data.

    abstract::Some of the patients with epithelial ovarian cancer will not respond to initial therapy. These patients have a poor prognosis. Our aim was to identify patients with a worse prognosis by integrating clinical, pathologic, and genomic data. Using publicly available genomic data and integrating it with clinical data, we s...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/GRF.0000000000000493

    authors: Newtson AM,Devor EJ,Gonzalez Bosquet J

    更新日期:2020-03-01 00:00:00

  • Characterization of a TP53 Somatic Variant of Unknown Function From an Ovarian Cancer Patient Using Organoid Culture and Computational Modeling.

    abstract::In our proof-of-concept study of 1 patient with stage IIIC carcinosarcoma of the ovary, we discovered a rare mutation in the tumor suppressor, TP53, that results in the deletion of N131. Immunofluorescence imaging of the organoid culture revealed hyperstaining of p53 protein. Computational modeling suggests this resid...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/GRF.0000000000000516

    authors: Bi J,Thiel KW,Litman JM,Zhang Y,Devor EJ,Newtson AM,Schnieders MJ,Gonzalez Bosquet J,Leslie KK

    更新日期:2020-03-01 00:00:00

  • Intrahepatic Cholestasis of Pregnancy.

    abstract::Intrahepatic cholestasis of pregnancy is a common disorder of pregnancy manifested by pruritus and elevated bile acids. The etiology of cholestasis is poorly understood and management is difficult due to the paucity of data regarding its diagnosis, treatment, and related adverse outcomes. In this article, we review th...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/GRF.0000000000000495

    authors: Smith DD,Rood KM

    更新日期:2020-03-01 00:00:00

  • Updates in the Approach to Chronic Pelvic Pain: What the Treating Gynecologist Should Know.

    abstract::Chronic pelvic is a multifaceted condition that often has both peripheral and central generators of pain. Despite its high prevalence, the evaluation and management of a pelvic pain patient often present many challenges to the practicing gynecologist. As with many other chronic pain conditions, pain severity does not ...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/GRF.0000000000000486

    authors: Carey ET,Moore K

    更新日期:2019-12-01 00:00:00

  • Risk Management in Obstetrics and Gynecology.

    abstract::This article will review the basic principles of risk management, the role of the risk manager, and the importance of risk management in the patient safety movement as it pertains to obstetrics and gynecology. Several tools that are used by risk managers including risk assessments and root cause analyses will be used ...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000473

    authors: Klein VR

    更新日期:2019-09-01 00:00:00

  • Hyperthyroidism During Pregnancy: A Clinical Approach.

    abstract::Hyperthyroidism is relatively uncommon during pregnancy. However, those caring for pregnant patients should be versed in the evaluation and management of hyperthyroidism, as there are potential maternal and fetal implications that are related to the disease and to treatment. The differential diagnosis of hyperthyroidi...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000435

    authors: Cuff RD

    更新日期:2019-06-01 00:00:00

  • Expanded Preconception Carrier Screening in Clinical Practice: Review of Technology, Guidelines, Implementation Challenges, and Ethical Quandaries.

    abstract::In the last 10 years, expanded preconception carrier screening has become widely available and helps patients/couples make more informed decisions with regard to their reproductive options and facilitates more effective preconception planning, prenatal diagnosis, condition-specific counseling, and condition-specific c...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000437

    authors: Zhang T,Madeira J,Lu Y,Sun Y,Mertes H,Pennings G,Lindheim SR

    更新日期:2019-06-01 00:00:00

  • Antenatal Management of Placenta Accreta.

    abstract::Predelivery diagnosis of placenta accreta, increta, and percreta (from here referred to as placenta accreta, unless otherwise noted) has increasingly created opportunities to optimize antenatal management. Despite the increased frequency of placenta accreta today, occurring in as many as 1 in 533 to 1 in 272 deliverie...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000394

    authors: Haunschild C,Yeaton-Massey A,Lyell DJ

    更新日期:2018-12-01 00:00:00

  • Pathophysiology of Placenta Accreta Spectrum Disorders: A Review of Current Findings.

    abstract::Current findings continue to support the concept of a biologically defective decidua rather than a primarily abnormally invasive trophoblast. Prior cesarean sections increase the risk of placenta previa and both adherent and invasive placenta accreta, suggesting that the endometrial/decidual defect following the iatro...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000392

    authors: Jauniaux E,Burton GJ

    更新日期:2018-12-01 00:00:00

  • The Utilization of Interventional Radiologic Procedures in the Surgical Management of Placenta Accreta Syndrome.

    abstract::The role of Interventional radiologic procedures for the management of suspected placenta accreta spectrum (PAS) has evolved considerably over last 3 decades. In this article, the authors describe the various techniques of vascular occlusion for the management of PAS and provide a brief review of the literature examin...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000401

    authors: Shrivastava VK,Nageotte MP

    更新日期:2018-12-01 00:00:00

  • Gender-Affirming Hormone Therapy for Transgender Females.

    abstract::The provision of hormone therapy, both estrogens and antiandrogens, to adult transgender females is well within the scope of practice of the obstetrician gynecologist. The goal is to induce feminizing changes and suppress previously developed masculinization. Estrogens in sufficient doses will usually achieve both goa...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000396

    authors: Randolph JF Jr

    更新日期:2018-12-01 00:00:00

  • Conservative Management of Placenta Accreta Spectrum.

    abstract::The purpose of this review was to assist obstetricians and gynecologists in considering the most appropriate conservative treatment option to manage women with placenta accreta spectrum according to their individual need and local expertise of the heath care team. The issue is challenging, as the quality of evidence w...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000395

    authors: Sentilhes L,Kayem G,Silver RM

    更新日期:2018-12-01 00:00:00

  • Genitourinary Syndrome of Menopause.

    abstract::Genitourinary syndrome of menopause (GSM) describes a collection of exam findings and bothersome symptoms associated with estrogen deficiency involving changes to the labia, introitus, clitoris, vagina, urethra, and bladder. Vulvovaginal atrophy is a component of GSM. GSM is a highly prevalent medical condition with a...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000380

    authors: Shifren JL

    更新日期:2018-09-01 00:00:00

  • Reducing Maternal Mortality and Severe Maternal Morbidity Through State-based Quality Improvement Initiatives.

    abstract::State Perinatal Quality Collaboratives (PQCs) represent a major advance for scaling up quality improvement efforts for reducing maternal mortality and severe maternal morbidity. The critical roles of partners, rapid-cycle low-burden data systems, and linkage to maternal mortality review committees are reviewed. The ch...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/GRF.0000000000000361

    authors: Main EK

    更新日期:2018-06-01 00:00:00

  • A View From the UK: The UK and Ireland Confidential Enquiry into Maternal Deaths and Morbidity.

    abstract::The UK Confidential Enquiry into Maternal Deaths has been in operation for more than 60 years, during which time maternal mortality rates have fallen 10-fold. The program includes two aspects, surveillance and confidential case review, providing different information to aid quality improvement in maternity care. The e...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/GRF.0000000000000352

    authors: Knight M,Tuffnell D

    更新日期:2018-06-01 00:00:00

  • Prevention and Management of Stroke in Obstetrics and Gynecology.

    abstract::Stroke risk is 3 times higher in pregnancy than in the general young adult population and carries high morbidity and mortality risks. The recognition of signs and symptoms of stroke and other serious cerebrovascular disorders in pregnant and postpartum patients is important for the obstetrician to be able to initiate ...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000367

    authors: Barghouthi T,Bushnell C

    更新日期:2018-06-01 00:00:00

  • Ultrasound Findings Associated With Antepartum Viral Infection.

    abstract::This article reviews the sonographic manifestations of fetal infection and the role of ultrasound in the evaluation of the fetus at risk for congenital infection. Several ultrasound findings have been associated with in utero fetal infections. For the patient with a known or suspected fetal infection, sonographic iden...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000342

    authors: Crino JP,Driggers RW

    更新日期:2018-03-01 00:00:00

  • Management of Preinvasive Lesions.

    abstract::Serous tubal intraepithelial carcinoma is considered the precursor lesion of high-grade serous carcinoma, and found in both low-risk and high-risk populations. Isolated serous tubal intraepithelial carcinomas in patients with BRCA1/2 mutations are detected in ∼2% of patients undergoing risk-reducing bilateral salpingo...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000316

    authors: Patrono MG,Corzo C,Iniesta M,Ramirez PT

    更新日期:2017-12-01 00:00:00

  • Medical Management of Endometriosis.

    abstract::Endometriosis is a chronic medical condition that affects around 6% to 10% of reproductive age women. Pelvic pain, dysmenorrhea, and infertility are the most common presenting symptoms. The disease is characterized by estrogen-dependent growth of the endometrial glands and stroma outside the endometrial cavity. The di...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/GRF.0000000000000292

    authors: Rafique S,Decherney AH

    更新日期:2017-09-01 00:00:00

  • Surgery and Endometriosis.

    abstract::Care of the endometriosis patient today can be complex and difficult. Once medical management has been exhausted and symptoms persist patients desire further treatment options. This chapter takes an evidence-based approach at discussion of patient surgcical options for treatment of endometriosis symptoms. Surgical tec...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/GRF.0000000000000291

    authors: Zanelotti A,Decherney AH

    更新日期:2017-09-01 00:00:00

  • Failed Intrauterine Pregnancy: What Is a Failed Pregnancy, What Is Not?

    abstract::Pregnancy failure is defined as a lack of sonographic evidence of current or expected viability. Technologic advances in ultrasound imaging continue to redefine diagnostic criteria of pregnancy failure or success. When evaluating a pregnancy, the first step is an assessment of maternal risk factors for failure. Imagin...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/GRF.0000000000000301

    authors: Canavan TP

    更新日期:2017-09-01 00:00:00

  • New Developments in Minimally Invasive Gynecologic Oncology Surgery.

    abstract::Minimally invasive surgery continues to transform the field of gynecologic oncology and has now become the standard of care for many early-stage malignancies. The proven benefits of minimally invasive surgery are driving the rapid introduction and dissemination of novel technologies and the increasing ability to perfo...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000286

    authors: Stewart KI,Fader AN

    更新日期:2017-06-01 00:00:00

  • Increasing Utilization of Minimally Invasive Hysterectomy.

    abstract::Once the decision to perform a hysterectomy has been made, the type and route of hysterectomy must be chosen, and efforts made to accomplish the surgery as safely as possible. Hysterectomy can be performed vaginally, abdominally with laparoscopic or robotic assistance, or open. The main goal of gynecologic surgeons sh...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/GRF.0000000000000283

    authors: Walters MD,Ridgeway BM

    更新日期:2017-06-01 00:00:00

  • Low-Molecular-Weight Heparin for the Prevention of Placenta-mediated Pregnancy Complications.

    abstract::During the past decade, prophylactic doses of low-molecular-weight heparin (LMWH) have been suggested to decrease the risk of placental-mediated complications. Herein, we review the prospective randomized trials that addressed the usefulness of LMWH in preventing placental-mediated complications in high-risk women. In...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000252

    authors: Haddad B,Lecarpentier E,Touboul C,Sibai BM

    更新日期:2017-03-01 00:00:00

  • Breast Cancer Posttreatment Surveillance: Diagnosis and Management of Recurrent Disease.

    abstract::There has been a steady decline in breast cancer mortality that has led to a significant increase in the number of patients surviving breast cancer. We will review in this manuscript the evidence and guidelines for posttreatment surveillance of patients with breast cancer as well as the management options for patients...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000243

    authors: Karam AK

    更新日期:2016-12-01 00:00:00

  • Current Management of the Axilla.

    abstract::Despite advances in estimating prognosis and predicting response to adjuvant systemic therapy, the status of the axillary lymph nodes remains a critical component in initial surgical planning and in determining therapeutic strategies for patients with breast cancer. Buoyed by evidence from multi-institutional randomiz...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000232

    authors: McCARTAN D,Gemignani ML

    更新日期:2016-12-01 00:00:00

  • Shoulder Dystocia: Incidence and Risk Factors.

    abstract::Shoulder dystocia complicates ∼1% of vaginal births. Although fetal macrosomia and maternal diabetes are risk factors for shoulder dystocia, for the most part its occurrence remains largely unpredictable and unpreventable. ...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000227

    authors: Ouzounian JG

    更新日期:2016-12-01 00:00:00

  • Exercise in Pregnancy: Guidelines.

    abstract::In recent years it has been recognized that in all phases of life, including pregnancy, physical activity promotes health benefits and precludes comorbidities, the scientific evidence is indisputable. Several organizations around the world have updated in recent years the guidelines and recommendations for exercise in...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000223

    authors: Artal R

    更新日期:2016-09-01 00:00:00

  • Controversies in Screening Mammography.

    abstract::The utility and effectiveness of screening mammography in diagnosing breast cancer at earlier stages and reducing disease-specific mortality remain controversial especially as to when to start and stop routine mammographic screening, and whether mammograms should be performed annually or biennially in average-risk wom...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/GRF.0000000000000205

    authors: Swain M,Jeudy M,Pearlman MD

    更新日期:2016-06-01 00:00:00

  • Cerclage: Indications and Patient Counseling.

    abstract::Cervical cerclage is a surgical procedure to prevent preterm birth. There are currently 3 main indications, based on either history, ultrasound, or physical exam changes. ...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/GRF.0000000000000185

    authors: Roman A,Suhag A,Berghella V

    更新日期:2016-06-01 00:00:00

  • Use of Cervical Pessary in the Management of Cervical Insufficiency.

    abstract::Prevention of spontaneous preterm birth is an important public health priority. Pessary may be a potential therapy in cases of cervical insufficiency, in singleton and multiple gestations. Availability of transvaginal sonography for accurate assessment of cervical length is allowing for the tailoring of therapy to a m...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000196

    authors: Timofeev J

    更新日期:2016-06-01 00:00:00

  • Antepartum Care of the Obese Patient.

    abstract::In the United States, roughly half of women are either overweight (24.5%) or obese (21.4%) when they become pregnant. Women who are obese before pregnancy are at increased risk for a number of pregnancy complications relative to normal-weight women. Specifically, obesity is associated with significantly increased mate...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000173

    authors: Simhan HN

    更新日期:2016-03-01 00:00:00

  • Controversies in the Management of Endometrioma: To Cure Sometimes, to Treat Often, to Comfort Always?

    abstract::Endometriomas are common in reproductive-aged women, but controversy exists regarding their management. PubMed was searched to identify pertinent studies on outcomes of medical and surgical management of endometrioma, with focus on randomized controlled trials and meta-analyses. Surgical excision is more effective tha...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000151

    authors: Johnstone EB,Link MH

    更新日期:2015-12-01 00:00:00

  • Associations Among Lactation, Maternal Carbohydrate Metabolism, and Cardiovascular Health.

    abstract::In mammalian reproductive physiology, lactation follows pregnancy; growing evidence suggests that disruption of this physiology affects a woman's lifetime risk of metabolic disease. These differences may reflect lactation-induced mobilization of fat stores and modulation of maternal stress reactivity. In addition, con...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000155

    authors: Stuebe A

    更新日期:2015-12-01 00:00:00

  • The Normal Vulva, Vulvar Examination, and Evaluation Tools.

    abstract::The appearance of the female external genitalia is key for understanding and diagnosing many diseases that women of all ages encounter. Alas, the normal appearance of the vulva is an elusive concept, scarcely represented in textbooks, and the growing number of vulvar cosmetic surgery calls for a review of the normal a...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000123

    authors: Cohen Sacher B

    更新日期:2015-09-01 00:00:00

  • Higher-order Multiples.

    abstract::Higher-order multiple gestations have increased since the advent of advanced reproductive technologies. These pregnancies present unique risks to both mothers and fetuses. It is imperative that early diagnosis of chronicity be determined and that proper counseling is performed, so patients understand the risks, evalua...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000121

    authors: Stone J,Kohari KS

    更新日期:2015-09-01 00:00:00

  • "How-To" Guide to Pelvic Floor Muscle Dysfunction.

    abstract::The purpose of this paper is to assist the clinician in recognizing pelvic floor muscle dysfunction in women with vulvar symptoms, to provide general treatment algorithms, and to facilitate understanding of the scientific rationale behind appropriate treatment. In short, this paper is meant to provide a "how-to" guide...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/GRF.0000000000000135

    authors: Albrecht KB

    更新日期:2015-09-01 00:00:00

  • Induction of Labor and Cesarean: What is the True Relationship?

    abstract::It is a commonly held belief that labor induction increases the risk of cesarean delivery; women who are induced are at higher risk of cesarean as compared with those in spontaneous labor. This comparison group is inaccurate, however, as women and providers cannot choose spontaneous labor as the alternative to labor i...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000112

    authors: Little SE,Caughey AB

    更新日期:2015-06-01 00:00:00

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