Low-Molecular-Weight Heparin for the Prevention of Placenta-mediated Pregnancy Complications.

Abstract:

:During the past decade, prophylactic doses of low-molecular-weight heparin (LMWH) have been suggested to decrease the risk of placental-mediated complications. Herein, we review the prospective randomized trials that addressed the usefulness of LMWH in preventing placental-mediated complications in high-risk women. Inclusion criteria and results of these trials are heterogeneous. Unlike older trials (3 of 4 are single center), recent trials (all are multicenter) do not show beneficial effect of LMWH. There is certainly a need of complementary research before stating on the usefulness of LMWH in the prevention of placenta-mediated pregnancy complications in women at high risk.

journal_name

Clin Obstet Gynecol

authors

Haddad B,Lecarpentier E,Touboul C,Sibai BM

doi

10.1097/GRF.0000000000000252

subject

Has Abstract

pub_date

2017-03-01 00:00:00

pages

153-160

issue

1

eissn

0009-9201

issn

1532-5520

journal_volume

60

pub_type

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