Screening for fetal aneuploidy: is maternal age relevant?

Abstract:

:The process of genetic screening has evolved from a simple notation of maternal age to a complex algorithm incorporating age, maternal serum screening, and sonographic findings. The extent to which each of these variables should contribute to the overall screening result is much debated and deserves continued research. It is clear that maternal age provides useful information when used as part of this equation but should not represent the sole screening modality. The use of genetic screening in a general population should be examined in terms of cost effectiveness without sacrificing patient preference and autonomy.

journal_name

Clin Obstet Gynecol

authors

Hawk AF,Saller DN

doi

10.1097/GRF.0b013e3182488309

subject

Has Abstract

pub_date

2012-03-01 00:00:00

pages

217-25

issue

1

eissn

0009-9201

issn

1532-5520

pii

00003081-201203000-00019

journal_volume

55

pub_type

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