解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:PURPOSE:To report complications of cosmetic artificial iris implantation and explantation outcomes. SETTING:Stein Eye Institute DESIGN: : Retrospective case series METHODS: : Review of medical records of 12 patients (24 eyes) who presented to us after being implanted with cosmetic artificial irises elsewhere. Data col...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2021.01.005
更新日期:2021-01-22 00:00:00
abstract:OBJECTIVE:To elucidate molecular risk factors for posterior segment uveitis using a functional genomics approach. DESIGN:Genetic association cohort study. METHODS:Setting: Single-center study at an academic referral center. STUDY POPULATION:164 patients with clinically diagnosed uveitis of the posterior segment. MA...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.07.021
更新日期:2021-01-01 00:00:00
abstract:PURPOSE:To describe the validation and implementation of an automated system for the detection and quantification of guttae in Fuchs endothelial corneal dystrophy (FECD). DESIGN:Observational reliability study. METHODS:Patients with FECD underwent retroillumination corneal photography, followed by determination of th...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.07.029
更新日期:2021-01-01 00:00:00
abstract:PURPOSE:To investigate the effect of refractive astigmatism on all-distance visual acuity (VA) in eyes implanted with a diffractive trifocal or bifocal intraocular lens (IOL). DESIGN:Cross-sectional study. METHODS:Fifty eyes with trifocal IOLs (PanOptix; Alcon) and 50 eyes with bifocal IOLs (ReSTOR +3D) were enrolled...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.07.051
更新日期:2021-01-01 00:00:00
abstract:PURPOSE:To determine the prevalence of artifacts on segmented spectral-domain optical coherence tomography (SDOCT) images and assess their impact on the interpretation of glaucomatous progression in the retinal nerve fiber layer (RNFL) profile and macular thickness map. DESIGN:Retrospective reliability analysis. METH...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.08.018
更新日期:2021-01-01 00:00:00
abstract:PURPOSE:To compare the accuracy of toric intraocular lens (IOL) alignment and visual outcomes using femtosecond laser-assisted capsulotomy marking (CM) versus conventional slit lamp-assisted manual marking (MM). DESIGN:Prospective cohort study. METHODS:A total of 57 patients who required cataract surgery and toric IO...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.08.041
更新日期:2021-01-01 00:00:00
abstract:PURPOSE:To characterize crystalline lens dimensions derived from in-vivo spectral-domain optical coherence tomography (SD-OCT) and identify associations between these parameters, ocular biometry and age. METHODS:In this retrospective study, lens thickness (LT), lens diameter (LD) and lens volume (LV) were measured int...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.12.021
更新日期:2020-12-29 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate the baseline features associated with blindness in a cohort of children with primary congenital glaucoma (PCG) from a hospital registry. METHODS:Setting: Observational cohort study DESIGN: Retrospective clinical cohort study STUDY POPULATION: The registry included all chil...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.12.014
更新日期:2020-12-21 00:00:00
abstract:PURPOSE:To estimate point prevalence of uveal melanoma in the patients with germline BAP1 pathogenic variant. DESIGN:Cohort study with risk assessment using Bayesian analysis. METHODS:The point prevalence estimate was obtained by Bayes's rule of reverse conditional probabilities. The probability of uveal melanoma giv...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.12.005
更新日期:2020-12-11 00:00:00
abstract:OBJECTIVE:To determine whether parapapillary choroidal microvasculature (PPCMv) density as measured by optical coherence tomography angiography differs between pseudoexfoliation syndrome (PXS) and pseudoexfoliation glaucoma (PXG). DESIGN:Cross-sectional study. METHODS:One hundred ninety-two eyes of 120 subjects from ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.12.002
更新日期:2020-12-10 00:00:00
abstract:PURPOSE:To critically evaluate the potential impact of the coronavirus disease (COVID-19) pandemic on global ophthalmology and VISION 2020. DESIGN:Perspective supplemented with epidemiologic insights from available online databases. METHODS:We extracted data from the Global Vision Database (2017) and Global Burden of...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.11.016
更新日期:2020-12-09 00:00:00
abstract:PURPOSE:To study the effects of age, sex, intraocular pressure (IOP), corneal thickness, axial length (AXL), disc area, and the signal strength of the scan on optical coherence tomography (OCT) parameters of normal subjects in the L V Prasad Eye Institute-Glaucoma Epidemiological and Molecular Genetic Study (LVPEI-GLEA...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.11.015
更新日期:2020-12-08 00:00:00
abstract:PURPOSE:To compare the efficacy of intraoperative scleral application with subconjunctival injection of mitomycin C (MMC) in trabeculectomy. DESIGN:Prospective, randomized, interventional study. METHODS:This study took place in a single clinical practice in an academic setting. Patients had medically uncontrolled gla...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ajo.2020.07.002
更新日期:2020-12-01 00:00:00
abstract:PURPOSE:To analyze the comparative safety and efficacy of two techniques of corneal neurotization (CN) (direct corneal neurotization [DCN] vs indirect corneal neurotization [ICN]) for the treatment of neurotrophic keratopathy (NK). DESIGN:Multicenter interventional prospective comparative case series. METHODS:This st...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ajo.2020.07.003
更新日期:2020-12-01 00:00:00
abstract:PURPOSE:To compare rotational stability and its influencing factors in 3 different widely used hydrophobic acrylic intraocular lenses (IOLs) from the end of surgery (EoS) to 4-7 months (6 months) in over 380 eyes. DESIGN:Prospective interventional comparative clinical study. METHODS:Setting: Department of Ophthalmolo...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1016/j.ajo.2020.07.019
更新日期:2020-12-01 00:00:00
abstract:PURPOSE:We investigated meetings of the Dermatologic and Ophthalmic Drug Advisory Committee (DODAC) and the Ophthalmic Devices Panel (ODP) of the Food and Drug Administration (FDA) to determine whether a relationship exists between receipt of industry payments by speakers of the Open Public Hearing (OPH) portion and th...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.09.043
更新日期:2020-11-06 00:00:00
abstract:PURPOSE:To evaluate the repeatability of an extensive number of relevant indices with the Pentacam HR in keratoconus of varying severity and normal eyes. DESIGN:Reliability analysis. METHODS:This study was performed at Antwerp University Hospital, Belgium, and enrolled 20 healthy volunteers (20 eyes) and 69 patients ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.06.013
更新日期:2020-11-01 00:00:00
abstract:PURPOSE:To evaluate the natural history and ophthalmologic morbidity of Mycoplasma pneumoniae-induced rash and mucositis (MIRM) and propose a treatment algorithm. DESIGN:Retrospective, interventional case series. METHODS:Retrospective chart review of all MIRM patients examined by the department of ophthalmology at a ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.06.010
更新日期:2020-11-01 00:00:00
abstract:PURPOSE:This study sought to compare the postoperative visual outcomes of toric implantable collamer lens (T-ICL) with toric Artiflex (T-Artiflex) lenses. DESIGN:Alternating treatment, contralateral eye matched clinical study. METHODS:This study compared 82 eyes of 41 patients with T-ICL lenses in one eye and toric A...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.06.021
更新日期:2020-11-01 00:00:00
abstract:PURPOSE:To evaluate the in vivo durability of the surface and optical properties of the implantable Collamer lens (ICL). DESIGN:Retrospective case series. METHODS:We included patients who developed cataracts after having undergone ICL implantation from March 2003 to May 2014 and underwent ICL explantation followed by...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.06.025
更新日期:2020-11-01 00:00:00
abstract:PURPOSE:To determine whether clinical features and visual outcomes of myelin oligodendrocyte glycoprotein antibody-associated optic neuritis (MOG-ON) differ between White and Asian subjects. DESIGN:Multicenter retrospective cohort. METHODS:This was a multicenter study of 153 subjects who were White or Asian with a hi...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ajo.2020.07.008
更新日期:2020-11-01 00:00:00
abstract:PURPOSE:We sought to assess the effects of exposure to secondhand smoke (SHS) on peripapillary retinal nerve fiber layer (p-RNFL) thickness in children. DESIGN:Cross-sectional study. METHODS:Children 6-8 years of age were consecutively recruited from the population-based Hong Kong Children Eye Study. All participants...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.10.016
更新日期:2020-10-29 00:00:00
abstract:PURPOSE:To describe the pre-exudative stage of exudative perifoveal vascular anomalous complex (ePVAC), referred to as nonexudative PVAC (nePVAC). DESIGN:Retrospective noncomparative case series. METHODS:Patients diagnosed with nePVAC were identified at 4 retina referral centers worldwide. Multimodal retinal imaging,...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ajo.2020.04.025
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:To determine whether an association exists between dry eye disease (DED) and statin use and/or dyslipidemia. DESIGN:Retrospective, case-control study. METHODS:Setting: University of North Carolina (UNC)-affiliated healthcare facilities. STUDY POPULATION:72,931 patients seen at UNC ophthalmology clinics over ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.05.007
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:This study compared the outcomes after Descemet's membrane endothelial keratoplasty (DMEK) in pseudophakic patients with the outcomes after DMEK combined with cataract surgery (triple-DMEK) in patients with Fuchs' endothelial dystrophy (FED). DESIGN:Retrospective, single-institution, interventional, consecutiv...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.05.003
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:To describe patients with late-onset pseudoxanthoma elasticum (PXE) associated with a likely hypomorphic ABCC6 variant. DESIGN:Retrospective observational case series. METHODS:Clinical evaluation, multimodal retinal imaging, genetic testing, and molecular modeling. RESULTS:Three patients, in whom vision symp...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.05.009
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:To characterize the progression of optical gaps and expand the known etiologies of this phenotype. DESIGN:Retrospective cohort study. METHODS:Thirty-six patients were selected based on the identification of an optical gap on spectral-domain optical coherence tomography (OCT) from a large cohort of patients (N...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.05.016
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:To report the population-based birth prevalence of pseudostrabismus in the first year of life and the subsequent diagnosis of strabismus. DESIGN:Retrospective population-based cohort study. METHODS:All residents of Olmsted County, Minnesota ≤1 year old diagnosed with pseudostrabismus from January 1, 2005 thro...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.06.002
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:To perform 11- and 2-year health care sector (ophthalmic) and societal cost perspective reference case, cost-utility analyses comparing bevacizumab, ranibizumab, and aflibercept monotherapies for neovascular age-related macular degeneration (NVAMD). DESIGN:Cost-utility analysis. METHODS:The authors performed ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.05.029
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:We sought to assess the correlation of corneal endothelial cell (CEC) density to alterations of collagen composition of Descemet membrane (DM) in advanced Fuchs endothelial corneal dystrophy (FECD) and to image such changes by slit-lamp biomicroscopy in vivo. DESIGN:Prospective, observational consecutive case ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.09.030
更新日期:2020-09-21 00:00:00
abstract:PURPOSE:Macular imaging with optical coherence tomography (OCT) measures the most critical retinal ganglion cells (RGCs) in the human eye. The goal of this perspective is to review the challenges to detection of glaucoma progression with macular OCT imaging and propose ways to enhance its performance. DESIGN:Perspecti...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.09.026
更新日期:2020-09-18 00:00:00
abstract:PURPOSE:To compare tear protein markers between normal subjects and patients with dry eye (DE) and high and low lymphotoxin-alpha (LT-α) levels. DESIGN:Prospective cross-sectional study. METHODS:Patients with DE were divided into low (≤700 pg/mL) and high (>700 pg/mL) LT-α groups. Twelve protein markers were measured...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.03.013
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:The prediction of atherosclerosis using retinal fundus images and deep learning has not been shown possible. The purpose of this study was to develop a deep learning model which predicted atherosclerosis by using retinal fundus images and to verify its clinical implications by conducting a retrospective cohort ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.03.027
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:To correlate in vivo confocal microscopy morphologic features (IVCM-MF) and Acanthamoeba cyst density (ACD) with final best-corrected visual acuity (BCVA) in Acanthamoeba keratitis (AK). DESIGN:Retrospective cohort study. METHODS:Patient demographics, treatment outcome, and corresponding IVCM-MF performed at ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.03.048
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:Patients with idiopathic nystagmus syndrome often develop an abnormal head position. A horizontal face turn can be treated with the augmented Kestenbaum procedure, while patients with a chin up or chin down position can be treated with surgery on the vertical recti and/or oblique muscles. Although rare, some pa...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.04.034
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:To compare the prediction accuracy of new intraocular lens (IOL) calculation formulas (Barrett Universal II [BUII], Emmetropia Verifying Optical [EVO], Kane and Ladas Super formula) and traditional formulas (Haigis, Hoffer Q, Holladay 1, and SRK/T) with Wang-Koch (WK) axial length (AL) adjustment in vitrectomiz...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.04.035
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:To evaluate the importance of nutritional supplements, dietary pattern, and genetic associations in age-related macular degeneration (AMD); and to discuss the technique of artificial intelligence/deep learning to potentially enhance research in detecting and classifying AMD. DESIGN:Retrospective literature rev...
journal_title:American journal of ophthalmology
pub_type:
doi:10.1016/j.ajo.2020.05.042
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:To describe follow-up rates for patients referred for outpatient ophthalmic care after emergency department (ED) discharge and identify patient and visit characteristics associated with loss to follow-up (LTFU). DESIGN:Single-institution retrospective cohort study. METHODS:We analyzed the medical records of 2...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.08.038
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:To comprehensively evaluate the effectiveness of different types of laser trabeculoplasty (LT) in the treatment of open-angle glaucoma. DESIGN:Systematic review and network meta-analysis. METHODS:Eligible randomized controlled trials (RCT) were identified by searching PubMed, EMBASE, Cochrane Library, SCOPUS,...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1016/j.ajo.2020.07.046
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:To investigate the relationship between intraretinal macular hemorrhage and visual acuity outcomes in eyes with central retinal vein occlusion or hemiretinal vein occlusion managed with aflibercept, bevacizumab, or observation. DESIGN:Retrospective analysis of data from 2 randomized clinical trials. METHODS:A...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.08.030
更新日期:2020-08-20 00:00:00