解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Not fully maturated immune system in preterm neonates may contribute to the increased susceptibility to infection. The levels of some cytokines can be useful in the prediction and diagnosis of sepsis in premature neonates. In the present study, we evaluated the potential predictive role of IFN-γ and IL-5 in cord and v...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2021-0206
更新日期:2021-01-11 00:00:00
abstract::[This corrects the article on p. 479 in vol. 14, PMID: 31231684.]. ...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 已发布勘误
doi:10.1515/med-2021-0006
更新日期:2020-11-27 00:00:00
abstract::Triple-negative breast cancer (TNBC) is a particularly aggressive subtype known for its extremely high drug resistance, progression, poor prognosis, and lack of clear therapeutic targets. Researchers are aiming to advance TNBC treatment worldwide. In the past 2-3 years, more positive results have emerged in the clinic...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章,评审
doi:10.1515/med-2020-0138
更新日期:2020-11-14 00:00:00
abstract:Aim:To compare the clinical effectiveness of the two most commonly used LMWHs, dalteparin (DALT) and enoxaparin (ENOX), in thromboprophylaxis of elective total hip replacement (THR) or total knee replacement (TKR). Material and methods:To the prospective, randomized study were included 66 adult patients qualified to u...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2020-0213
更新日期:2020-10-12 00:00:00
abstract::Long non-coding RNA forkhead box D2 adjacent opposite strand RNA 1 (FOXD2-AS1) has emerged as a potential oncogene in several tumors. However, its biological function and potential regulatory mechanism in glioma have not been fully investigated to date. In the present study, RT-qPCR was conducted to detect the levels ...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2020-0175
更新日期:2020-09-30 00:00:00
abstract::During radiotherapy treatment for cervical cancer, up to 84% of patients exhibit some form of acute radiation toxicity (ART). The primary aim of this clinical study is to determine the impact of angiotensin-converting enzyme (ACE) inhibitors, β-blockers and other risk factors such as the patient's anatomical character...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2020-0222
更新日期:2020-09-02 00:00:00
abstract:Objective:To explore the clinical significance and mechanisms of altered miRNAs in squamous cell carcinoma of head and neck (SCCHN) and provide references for SCCHN diagnosis and prognosis. Method:Differential expressed miRNAs (DEMs) in SCCHN were screened through gene expression omnibus (GEO) DataSets and verified by...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2020-0146
更新日期:2020-08-03 00:00:00
abstract::We aimed to investigate the CXCL13 concentration of the serum and cerebral spinal fluid (CSF) in human immunodeficiency virus (HIV)-negative latent syphilis patients with treatment failure and explore the change in CXCL13 after treatment. Sixty-eight latent syphilis patients with treatment failure (failure group), 68 ...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2020-0204
更新日期:2020-07-10 00:00:00
abstract::This study evaluates the efficacy and safety of bevacizumab (BEV) in the treatment of non-small cell lung cancer (NSCLC) patients with brain metastases (BM) by performing meta-analyses of response and survival indices. Seventeen studies were included. BEV treatment was associated with a lower new BM incidence (hazard ...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2020-0192
更新日期:2020-07-01 00:00:00
abstract:Background:Many factors contribute to successful nerve reconstruction. The correct technique of anastomosis is one of the key elements that determine the final result of a surgery. The aim of this study is to examine how useful an electromyography (EMG) can be as an objective intraoperative anastomosis assessment metho...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2020-0143
更新日期:2020-06-13 00:00:00
abstract::Recent studies have revealed that microRNAs regulate radiosensitivity of non-small cell lung cancer (NSCLC). The aim of this study was to investigate whether miR-101-3p is correlated with radiosensitivity of NSCLC. According to our results, miR-101-3p was downregulated in NSCLC tissues and cell lines. Moreover, miR-10...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2020-0044
更新日期:2020-06-07 00:00:00
abstract::Three-dimensional (3D) cell cultures were created with the use of fur keratin associated proteins (F-KAPs) as scaffolds. The procedure of preparation F-KAP involves combinations of chemical activation and enzymatic digestion. The best result in porosity and heterogeneity of F-KAP surface was received during pepsin dig...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2020-0031
更新日期:2020-04-03 00:00:00
abstract:Background:Long noncoding RNA (lncRNA) LINC00152 (CYTOR) has been reported to be upregulated and to serve as a diagnostic biomarker in multiple types of cancers, including laryngeal squamous cell cancer (LSCC). However, the functional role and molecular mechanisms of LINC00152 in LSCC progression need to be further inv...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2020-0035
更新日期:2020-03-26 00:00:00
abstract:Purpose:We hypothesized that the current criteria may be unsuitable for lacunar pontine infarctions (LPI) diagnosis and that size criteria may indicate different stroke mechanisms. Methods:A total of 102 patients with isolated pontine infarctions were divided into a parent artery disease (PAD) and non-PAD groups accor...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2020-0025
更新日期:2020-03-08 00:00:00
abstract:Background and aim:To explore the diagnostic value of recombinant heparin-binding hemagglutinin adhesin (HBHA) protein antigen in spinal tuberculosis. Materials and methods:Forty patients with spinal tuberculosis were included in the experimental group and 40 healthy people were included in the control group. Serum Ig...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2020-0017
更新日期:2020-02-28 00:00:00
abstract::Convolutional neural networks (CNNs) are a branch of deep learning which have been turned into one of the popular methods in different applications, especially medical imaging. One of the significant applications in this category is to help specialists make an early detection of skin cancer in dermoscopy and can reduc...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2020-0006
更新日期:2020-01-13 00:00:00
abstract:Background:Cardiac arrest related to nerve blockade using a local anaesthetic is a rare event. We report a case of bupivacaine severe cardiovascular toxicity following cervical paravertebral nerve block. Case presentation:A 44-year-old female was admitted to Republican Vilnius University Hospital, with symptoms of sus...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2019-0112
更新日期:2019-12-17 00:00:00
abstract::The aim of this study was to evaluate the role of miR-181a-5p in sepsis, and to further explore the molecular mechanism. RAW 264.7 cells were stimulated with 1 μg/ml LPS for 4 hours. Firstly, qRT-PCR and ELISA was adopted to evaluate the expression of miR-181a-5p and p ro-inflammatory cytokines in RAW 264.7 macrophage...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2019-0106
更新日期:2019-11-20 00:00:00
abstract::Previous studies indicated that chromosome 9 translocations are involved in reduced male fertility and increased chance of miscarriage in the female partner. The aim of this study was to review the clinical features and genetic counselling requirements of infertile men carrying chromosome 9 translocations. This study ...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2019-0100
更新日期:2019-11-10 00:00:00
abstract:Background:Numbers of the elderly have been on a steady increase both in Poland and other countries of the world. As they age, their health declines and they need help with their housekeeping. This, coupled with the transformation of intergenerational into single-generation or nuclear family structures, causes a marked...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2019-0035
更新日期:2019-04-24 00:00:00
abstract::Regional anaesthesia techniques in ophthalmology are usually utilized for day case surgery. During various procedures, profound akinesia of the eye and anaesthesia of the surgical site are required, both of which are achieved with retrobulbar block. Due to the anatomy of the eye, life-threatening complications are pos...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2019-0025
更新日期:2019-03-02 00:00:00
abstract:Background:To analyze the cardio-protective effects of ticagrelor in patients with acute coronary syndrome with S-T segment elevation. Methods:The sample was 200 patients who had been diagnosed with acute coronary syndrome accompanied by diabetes Mellitus type II. Only patients having ST segment elevation before the t...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2019-0017
更新日期:2019-02-20 00:00:00
abstract::Prostate cancer (PCa) is the second most diagnosed cancer in Western male population. In this study, we insert mK5 (the mutational kringle5 of human plasminogen) into a DD3-promoted (differential display code 3) oncolytic adenovirus to construct OncoAd.mK5.DD3. E1A.dE1B, briefly, OAd.DD3.mK5. DD3 is one of the most pr...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2019-0001
更新日期:2018-12-24 00:00:00
abstract::There are many determinants of vancomycin clearance, but these have not been analyzed separately in populations with different levels of renal function, which could be why some important factors have been missed. The aim of our study was to compare the pharmacokinetic parameters and factors that may affect vancomycin ...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2018-0068
更新日期:2018-10-22 00:00:00
abstract::Our study aimed to find out the views of nurses working in neonatal intensive care units about the limits of professional competencies and to identify situations where the limits are crossed. Methods:The research employed the focus group method. For this research we had three focus groups with nurses working in neona...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2018-0060
更新日期:2018-10-04 00:00:00
abstract:Objective:The aim of this study was to assess the diagnostic value of PET/CT for metastatic lymph nodes in cervical cancer patients. Methods:Searching in the databases including PubMed, Embase, Web of Science, Cochrane Library and Google Scholar about non-invasive modalities for detecting lymph nodes metastases during...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2018-0065
更新日期:2018-09-22 00:00:00
abstract::Performing accurate diagnosis using computed tomography (CT) in emergency medicine may reduce mortality rates in various diseases. In this observational, correlational and cross-sectional study, we conducted multiple regression analyses to investigate the relationship between CT utilization rates and mortality. In add...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2018-0058
更新日期:2018-09-14 00:00:00
abstract::In this study, an effective means for detecting cancer region through different types of medical image segmentation are presented and explained. We proposed a new method for cancer segmentation on the basis of fuzzy entropy with a level set (FELs) thresholding. The proposed method was successfully utilized to segment ...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2018-0056
更新日期:2018-09-08 00:00:00
abstract::Responsibility means responding to the damaging consequences of technical work and in this binding perspective the general principles of guilt in genetic diagnostics and related activities are not different from any other medical performance. Performing a genetic test however, especially when it has predictive charact...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2018-0046
更新日期:2018-08-24 00:00:00
abstract::This study is a case report, which presents a case of severe mitral regurgitation in a 77-year-old man. Two-dimensional transesophageal echocardiography (TEE), regurgitant jets directed anteriorly in early systole and centrally to laterally in late systole were seen, while three-dimensional TEE showed a flail posterio...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2018-0047
更新日期:2018-08-11 00:00:00
abstract::Melanin-concentrating hormone (MCH) is a cyclic 19 amino acid orexigenic hypothalamic peptide. MCH is located in the lateral and dorsal hypothalamus, as well as in the zona incerta. In mammals MCH increases food intake, contributes to regulation of energy balance, temperature, reproductive function, endocrine homeosta...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2018-0040
更新日期:2018-07-06 00:00:00
abstract::An 85-year-old female suffered pelvic fracture, multiple rib fractures, right hemopneumothorax, and blunt abdominal aortic injury in a traffic accident. After transfer to our hospital, transcatheter arterial embolization (TAE) was performed immediately for hemorrhage from the bilateral internal iliac arteries. Enhance...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2018-0031
更新日期:2018-05-24 00:00:00
abstract:Objective:Elevation of serum high sensitivity C-reactive protein (hs-CRP) level has been demonstrated as a risk factor for varying diseases, as well as a biomarker for predicting recovery after operation of lumber disc herniation. Our objective was to investigate the relationship between serum hs-CRP and sacroiliac (SI...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2018-0018
更新日期:2018-05-19 00:00:00
abstract::Arginine vasopressin can bind to high-affinity vasopressin V1a receptors in human leukocytes. This study aims to investigate the effects of arginine vasopressin on migration and chemotaxis of neutrophils and oxygen free radical release by human leukocytes. Neutrophils and monocytes were obtained from peripheral blood ...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2018-0020
更新日期:2018-05-09 00:00:00
abstract::Internal carotid artery (ICA) supraclinoid segment aneurysms extending into the sellar region and leading to pituitary dysfunction are a rare occurrence. To date, long-term follow up of pituitary function 2 years post-treatment has never been reported. Herein, we present a case of pituitary dysfunction due to an unrup...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2018-0021
更新日期:2018-04-18 00:00:00
abstract::One of the most dangerous cancers in humans is Melanoma. However, early detection of melanoma can help us to cure it completely. This paper presents a new efficient method to detect malignancy in melanoma via images. At first, the extra scales are eliminated by using edge detection and smoothing. Afterwards, the propo...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2018-0002
更新日期:2018-03-15 00:00:00
abstract:Objective:To observe and analyze the effect of color doppler ultrasonography (CDU) in uterine arterial embolization (UAE). Methods:160 cases of patients with uterine fibroid were selected in this study. CDU were performed on all patients before UAE as well as 5-9 days and 3-6 months after UAE, so as to observe the sha...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2017-0069
更新日期:2017-12-29 00:00:00
abstract::The term vein of Galen aneurysm is related to a group of different vascular anomalies, with one common distinction being the dilatation of the vein of Galen. It represents a rear vascular anomaly, whose incidence is yet unknown, although some authors suggest numbers around 1:25000 deliveries. It accounts for only 1% o...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2017-0054
更新日期:2017-12-05 00:00:00
abstract::To evaluate the clinical value of serum α-L-fucosidase (AFU), 5'-nucleotidase (5'-NT) and alpha fetoprotein (AFP) as biomarkers for primary hepatocellular carcinoma (PHC) diagnosis. METHODS:Thirty six primary hepatocellular carcinoma (PHC) patients and 36 healthy controls were recruited in this study from February 20...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2017-0051
更新日期:2017-10-11 00:00:00
abstract::The chief aim of this study was to analyze secondary healthcare providers' efficiency, focusing on the efficiency analysis of Slovene general hospitals. We intended to present a complete picture of technical, allocative, and cost or economic efficiency of general hospitals. METHODS:We researched the aspects of effici...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2017-0031
更新日期:2017-07-06 00:00:00