Comparison of low-molecular-weight heparins in thromboprophylaxis of major orthopaedic surgery - randomized, prospective pilot study.

Abstract:

Aim:To compare the clinical effectiveness of the two most commonly used LMWHs, dalteparin (DALT) and enoxaparin (ENOX), in thromboprophylaxis of elective total hip replacement (THR) or total knee replacement (TKR). Material and methods:To the prospective, randomized study were included 66 adult patients qualified to undergo THR or TKR (age 63 ± 12 years, 44 women). The patients were randomized to daily in-hospital subcutaneous prophylaxis with 5,000 I.U. of DALT or 40 mg of enoxaparin. Clinical and laboratory data were collected before surgery, and on 1st and 5th days after surgery. Results:Thirty-four patients were randomized to prophylaxis with ENOX and 32 with DALT. The groups did not differ significantly in age, sex, creatinine and most of the laboratory parameters. The compared groups had similar surgical parameters, but more patients in the ENOX group received red blood cell infusion (17(50%) vs 8(25%); p < 0.05). The Lee-White coagulation time mildly decreased in ENOX and DALT following the surgery (p = ns). There was a shortening of Duke's bleeding time in DALT after the surgery and it became significantly quicker than that in ENOX on Day 5 (p = 0.03). Conclusion:The observed difference in Duke's bleeding time and exceeding blood loss during the surgery on the enoxaparin demands confirmation, as it can be important information for clinical management.

journal_name

Open Med (Wars)

authors

Biławicz J,Lipa M,Wielgos M

doi

10.1515/med-2020-0213

subject

Has Abstract

pub_date

2020-10-12 00:00:00

pages

1048-1053

issue

1

issn

2391-5463

pii

med-2020-0213

journal_volume

15

pub_type

杂志文章
  • MicroRNA-181a-5p Regulates Inflammatory Response of Macrophages in Sepsis.

    abstract::The aim of this study was to evaluate the role of miR-181a-5p in sepsis, and to further explore the molecular mechanism. RAW 264.7 cells were stimulated with 1 μg/ml LPS for 4 hours. Firstly, qRT-PCR and ELISA was adopted to evaluate the expression of miR-181a-5p and p ro-inflammatory cytokines in RAW 264.7 macrophage...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2019-0106

    authors: Huang Z,Xu H

    更新日期:2019-11-20 00:00:00

  • Thresholding for Medical Image Segmentation for Cancer using Fuzzy Entropy with Level Set Algorithm.

    abstract::In this study, an effective means for detecting cancer region through different types of medical image segmentation are presented and explained. We proposed a new method for cancer segmentation on the basis of fuzzy entropy with a level set (FELs) thresholding. The proposed method was successfully utilized to segment ...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2018-0056

    authors: Maolood IY,Al-Salhi YEA,Lu S

    更新日期:2018-09-08 00:00:00

  • Is acute appendicitis still misdiagnosed?

    abstract:OBJECTIVE:The optimal diagnostics and treatment of acute appendicitis continues to be a challenge. A false positive diagnosis of appendicitis may lead to an unnecessary operation, which has been appropriately termed negative appendectomy. The aim of our study was to identify the effectiveness of preoperative investigat...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2016-0045

    authors: Kryzauskas M,Danys D,Poskus T,Mikalauskas S,Poskus E,Jotautas V,Beisa V,Strupas K

    更新日期:2016-07-22 00:00:00

  • A review of current progress in triple-negative breast cancer therapy.

    abstract::Triple-negative breast cancer (TNBC) is a particularly aggressive subtype known for its extremely high drug resistance, progression, poor prognosis, and lack of clear therapeutic targets. Researchers are aiming to advance TNBC treatment worldwide. In the past 2-3 years, more positive results have emerged in the clinic...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章,评审

    doi:10.1515/med-2020-0138

    authors: Shen M,Pan H,Chen Y,Xu YH,Yang W,Wu Z

    更新日期:2020-11-14 00:00:00

  • A confusing case report of pulmonary langerhans cell histiocytosis and literature review.

    abstract::Pulmonary Langerhans Cell Histiocytosis (PLCH) is a rare disease. From the insidious onset and nonspecific manifestations, it is difficult to diagnose PLCH. To help improve the diagnosis and therapy options of adult PLCH, we present this case report and literature review about a confusing case of PLCH. In this report,...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2016-0034

    authors: Li Y,Zhen W,Costable U,Jun X,Zhe R,YuPing M

    更新日期:2016-06-15 00:00:00

  • Limits of Professional Competency in Nurses Working in NICU.

    abstract::Our study aimed to find out the views of nurses working in neonatal intensive care units about the limits of professional competencies and to identify situations where the limits are crossed. Methods:The research employed the focus group method. For this research we had three focus groups with nurses working in neona...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2018-0060

    authors: Skorobogatova N,Žemaitienė N,Šmigelskas K,Tamelienė R,Markūnienė E,Stonienė D

    更新日期:2018-10-04 00:00:00

  • Trends in the treatment of risk factors for stroke in a Czech stroke unit.

    abstract::The goal of this study is to evaluate therapeutic trends for several diseases that represent risk factors for stroke. The relative frequency of therapy with compounds that influence the risk factors for stroke was monitored in a group of 3,290 patients who were hospitalised in the Stroke Unit at the University Hospita...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2015-0060

    authors: Simunek L,Krajickova D,Vysata O,Valis M

    更新日期:2015-10-26 00:00:00

  • Resuscitation Following a Bupivacaine Injection for a Cervical Paravertebral Block.

    abstract:Background:Cardiac arrest related to nerve blockade using a local anaesthetic is a rare event. We report a case of bupivacaine severe cardiovascular toxicity following cervical paravertebral nerve block. Case presentation:A 44-year-old female was admitted to Republican Vilnius University Hospital, with symptoms of sus...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2019-0112

    authors: Vosylius S,Uvarovas V,Svediene S,Satkauskas I

    更新日期:2019-12-17 00:00:00

  • Integration of human papillomavirus type 16 in cervical cancer cells.

    abstract::Cervical cancer remains an important cause of women morbidity and mortality. The progression of cervical pathology correlates with the HPV integration into the host genome. However, the data on the viral integration status in cervical dysplasias are controversial. The aim of the current study was to evaluate the statu...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2015-0001

    authors: Gudleviciene Z,Kanopiene D,Stumbryte A,Bausyte R,Kirvelaitis E,Simanaviciene V,Zvirbliene A

    更新日期:2014-09-25 00:00:00

  • Genetic Testing and Professional Responsibility: The Italian Experience.

    abstract::Responsibility means responding to the damaging consequences of technical work and in this binding perspective the general principles of guilt in genetic diagnostics and related activities are not different from any other medical performance. Performing a genetic test however, especially when it has predictive charact...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2018-0046

    authors: Bin P,Conti A,Capasso E,Fedeli P,Ceccarelli P,Policino F,Casella C,Delbon P

    更新日期:2018-08-24 00:00:00

  • Analysis of Ticagrelor's Cardio-protective Effects on Patients with ST-segment Elevation Acute Coronary Syndrome Accompanied with Diabetes.

    abstract:Background:To analyze the cardio-protective effects of ticagrelor in patients with acute coronary syndrome with S-T segment elevation. Methods:The sample was 200 patients who had been diagnosed with acute coronary syndrome accompanied by diabetes Mellitus type II. Only patients having ST segment elevation before the t...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2019-0017

    authors: Li DT,Li SB,Zheng JY,Tang HH,Qiu YG,Xue N,Cao Y

    更新日期:2019-02-20 00:00:00

  • CXCL13 concentration in latent syphilis patients with treatment failure.

    abstract::We aimed to investigate the CXCL13 concentration of the serum and cerebral spinal fluid (CSF) in human immunodeficiency virus (HIV)-negative latent syphilis patients with treatment failure and explore the change in CXCL13 after treatment. Sixty-eight latent syphilis patients with treatment failure (failure group), 68 ...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2020-0204

    authors: Zhang Y,Wang J,Wei Y,Liu H,Wu C,Qu B,Yan Y

    更新日期:2020-07-10 00:00:00

  • miR-101-3p sensitizes non-small cell lung cancer cells to irradiation.

    abstract::Recent studies have revealed that microRNAs regulate radiosensitivity of non-small cell lung cancer (NSCLC). The aim of this study was to investigate whether miR-101-3p is correlated with radiosensitivity of NSCLC. According to our results, miR-101-3p was downregulated in NSCLC tissues and cell lines. Moreover, miR-10...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2020-0044

    authors: Li Z,Qu Z,Wang Y,Qin M,Zhang H

    更新日期:2020-06-07 00:00:00

  • FPL tendon thickness, tremor and hand functions in Parkinson's disease.

    abstract:INTRODUCTION:In Parkinson's disease (PD), a resting tremor of the thumb may affect the flexor pollicis longus (FPL) and influence hand functions. We investigated the relationship between FPL tendon thickness and hand function in PD patients and compared these characteristics with those in healthy controls. METHODS:The...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2016-0004

    authors: Toktas H,Dundar U,Kusbeci ÖY,Ulasli AM,Toy O,Oruc S

    更新日期:2016-02-19 00:00:00

  • Diagnostic Value of Recombinant Heparin-binding Hemagglutinin Adhesin Protein in Spinal Tuberculosis.

    abstract:Background and aim:To explore the diagnostic value of recombinant heparin-binding hemagglutinin adhesin (HBHA) protein antigen in spinal tuberculosis. Materials and methods:Forty patients with spinal tuberculosis were included in the experimental group and 40 healthy people were included in the control group. Serum Ig...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2020-0017

    authors: Pu F,Feng J,Niu F,Xia P

    更新日期:2020-02-28 00:00:00

  • Learning curve for endorectal ultrasound in young and elderly: lights and shades.

    abstract::Aim of the study is to highlight difficulties faced by an inexperienced surgeon in approaching endorectal-ultrasound, trying to define when learning curve can be considered complete. A prospective analysis was conducted on endorectal-ultrasound performed for subperitoneal rectal adenocarcinoma staging in the period fr...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2016-0074

    authors: Surace A,Ferrarese A,Gentile V,Bindi M,Cumbo J,Solej M,Enrico S,Martino V

    更新日期:2016-11-19 00:00:00

  • Color Doppler Ultrasound in Uterine Arterial Embolization.

    abstract:Objective:To observe and analyze the effect of color doppler ultrasonography (CDU) in uterine arterial embolization (UAE). Methods:160 cases of patients with uterine fibroid were selected in this study. CDU were performed on all patients before UAE as well as 5-9 days and 3-6 months after UAE, so as to observe the sha...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2017-0069

    authors: Jinhe R

    更新日期:2017-12-29 00:00:00

  • Differentiation of Pontine Infarction by Size.

    abstract:Purpose:We hypothesized that the current criteria may be unsuitable for lacunar pontine infarctions (LPI) diagnosis and that size criteria may indicate different stroke mechanisms. Methods:A total of 102 patients with isolated pontine infarctions were divided into a parent artery disease (PAD) and non-PAD groups accor...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2020-0025

    authors: Yang L,Qin W,Li Y,Yang S,Gu H,Hu W

    更新日期:2020-03-08 00:00:00

  • Differences of plasma IL-1 and TNF-α in healthy Chinese Population.

    abstract::Pleiotropic proinflammatory cytokines, interleukin- 1 (IL-1) and tumor necrosis factor-α (TNF-α), involved in the regulations of various immune responses, inflammatory processes and hematopoiesis. In the present study, the expression levels of IL-1 and TNF-α were detected by enzyme-linked immunosorbent assay (ELISA). ...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2015-0044

    authors: Yuan J,Wang L,Lin Y,Chen J,Hu J

    更新日期:2015-06-09 00:00:00

  • Endometrial cancer and microsatellite instability status.

    abstract::Microsatellite instability (MSI) is an important factor in the development of various cancers as an identifier of a defective DNA mismatch repair system. The objective of our study was to define the association between microsatellite instability status and traditional clinicopathologic characteristics of endometrioid ...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2015-0005

    authors: Kanopiene D,Vidugiriene J,Valuckas KP,Smailyte G,Uleckiene S,Bacher J

    更新日期:2014-11-11 00:00:00

  • Plastination: ethical and medico-legal considerations.

    abstract::The international plastination phenomenon has proved to be immensely popular with audiences world-wide. Never before has the human body been exposed to public gaze in such an accessible manner. The exhibitions have perplexed many, included anatomists, some of whom find the display of human bodies unethical. The object...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2016-0095

    authors: Bin P,Conti A,Buccelli C,Addeo G,Capasso E,Piras M

    更新日期:2016-12-16 00:00:00

  • Garengeot's hernia: two case reports with CT diagnosis and literature review.

    abstract::Garengeot's hernia (GH) is defined as the presence of the appendix inside a femoral hernia. It occurs in 0.9% of femoral hernias and is usually an incidental finding during surgery. Its treatment is controversial and the aim of this article is to review the diagnostic methods and surgical considerations. We report two...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章,评审

    doi:10.1515/med-2016-0065

    authors: Garcia-Amador C,De la Plaza R,Arteaga V,Lopez-Marcano A,Ramia J

    更新日期:2016-10-07 00:00:00

  • Galen Vein Aneurysm- Challenge for Treatment.

    abstract::The term vein of Galen aneurysm is related to a group of different vascular anomalies, with one common distinction being the dilatation of the vein of Galen. It represents a rear vascular anomaly, whose incidence is yet unknown, although some authors suggest numbers around 1:25000 deliveries. It accounts for only 1% o...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2017-0054

    authors: Crnogorac S,Bozaric AV

    更新日期:2017-12-05 00:00:00

  • Strength and aerobic training in overweight females in Gdansk, Poland.

    abstract::We compared the effects of 16-week-training on rest metabolic rate, aerobic power, and body fat, and the post-exercise effects upon rest oxygen uptake and respiratory exchange ratio in overweight middle-aged females. Twenty nine overweight women (BMI 29.9 ± 1.2 kg*m-2) participated in training (3 days a week). The sub...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2015-0021

    authors: Sawczyn S,Mishchenko V,Moska W,Sawczyn M,Jagiełło M,Kuehne T,Kostrzewa-Nowak D,Nowak R,Cięszczyk P

    更新日期:2015-02-02 00:00:00

  • Pharmacokinetics of Vancomycin in Patients with Different Renal Function Levels.

    abstract::There are many determinants of vancomycin clearance, but these have not been analyzed separately in populations with different levels of renal function, which could be why some important factors have been missed. The aim of our study was to compare the pharmacokinetic parameters and factors that may affect vancomycin ...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2018-0068

    authors: Zaric RZ,Milovanovic J,Rosic N,Milovanovic D,Zecevic DR,Folic M,Jankovic S

    更新日期:2018-10-22 00:00:00

  • Research on the treatment of Pseudomonas aeruginosa pneumonia in children by macrolide antibiotics.

    abstract::To observe a therapeutic effect of macrolide antibiotics in children with Pseudomonas aeruginosa pneumonia. Fifty-four cases of children with Pseudomonas aeruginosa pneumonia were randomly divided into an observation group (n=30) and a control group (n=24). The observation group was treated with macrolide antibiotics ...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2015-0082

    authors: Huang XQ,Deng L,Lu G,He CH,Wu PQ,Xie ZW,Ashraf MA

    更新日期:2015-12-17 00:00:00

  • Can Keratin Scaffolds be used for Creating Three-dimensional Cell Cultures?

    abstract::Three-dimensional (3D) cell cultures were created with the use of fur keratin associated proteins (F-KAPs) as scaffolds. The procedure of preparation F-KAP involves combinations of chemical activation and enzymatic digestion. The best result in porosity and heterogeneity of F-KAP surface was received during pepsin dig...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2020-0031

    authors: Bochynska-Czyz M,Redkiewicz P,Kozlowska H,Matalinska J,Konop M,Kosson P

    更新日期:2020-04-03 00:00:00

  • Pituitary Dysfunction from an Unruptured Ophthalmic Internal Carotid Artery Aneurysm with Improved 2-year Follow-up Results: A Case Report.

    abstract::Internal carotid artery (ICA) supraclinoid segment aneurysms extending into the sellar region and leading to pituitary dysfunction are a rare occurrence. To date, long-term follow up of pituitary function 2 years post-treatment has never been reported. Herein, we present a case of pituitary dysfunction due to an unrup...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2018-0021

    authors: Qi M,Ye M,Li M,Zhang P

    更新日期:2018-04-18 00:00:00

  • Predictions and Outcomes of Atrial Fibrillation in the Patients with Acute Myocardial Infarction.

    abstract::The large epidemiological studies demonstrated that atrial fibrillation is correlated with high mortality and adverse events in patients with acute myocardial infarction. The aim of this study was to determinate predictors of atrial fibrillation develop during the hospital period in patients with acute myocardial infa...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2017-0018

    authors: Vukmirović M,Bošković A,Tomašević Vukmirović I,Vujadinovic R,Fatić N,Bukumirić Z,Vukmirović F

    更新日期:2017-05-02 00:00:00

  • Antibody Response to Live Attenuated Vaccines in Adults in Japan.

    abstract::The purpose of this study was to examine the efficacy rendered with a single dose of live attenuated measles, rubella, mumps, and varicella containing vaccine. We inoculated healthcare workers (HCWs) with a single dose of vaccine to a disease lacking in antibody titer for those not meeting the criteria of our hospital...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2016-0085

    authors: Ogawa T,Uchiyama-Nakamura F,Sugata-Tsubaki A,Yamada Y,Uno K,Kasahara K,Maeda K,Konishi M,Mikasa K

    更新日期:2016-11-26 00:00:00