Abstract:
:The goal of this study is to evaluate therapeutic trends for several diseases that represent risk factors for stroke. The relative frequency of therapy with compounds that influence the risk factors for stroke was monitored in a group of 3,290 patients who were hospitalised in the Stroke Unit at the University Hospital in Hradec Kralove between 2005 and 2012. For most drugs monitored, the reasons for the significant decrease or increase in use were causes other than the reduction of stroke risk. Despite this finding, the majority of statistically significant changes had, according to review of comparative studies, a positive effect on prevention of stroke. Motivation to change treatment of stroke risk factors, such as hypertension, diabetes mellitus and hypercholesterolemia, was mainly aimed at sufficient disease management with a minimum of adverse effects. On the other hand, optimization of stroke recurrence and economic factors were motivations to treatment changes in prevention with antiplatelets. Antidiabetics were associated with an increase in metformin use and reduction in insulin use. For antihypertensives, the most significant reduction was associated with the use of diuretics, although calcium channel blockers and beta-blockers are also less used. Additionally, the use of the ACE inhibitor ramipril increased.
journal_name
Open Med (Wars)journal_title
Open medicine (Warsaw, Poland)authors
Simunek L,Krajickova D,Vysata O,Valis Mdoi
10.1515/med-2015-0060subject
Has Abstractpub_date
2015-10-26 00:00:00pages
364-369issue
1issn
2391-5463pii
med-2015-0060journal_volume
10pub_type
杂志文章相关文献
Open Medicine文献大全abstract::Aim of the study is to highlight difficulties faced by an inexperienced surgeon in approaching endorectal-ultrasound, trying to define when learning curve can be considered complete. A prospective analysis was conducted on endorectal-ultrasound performed for subperitoneal rectal adenocarcinoma staging in the period fr...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2016-0074
更新日期:2016-11-19 00:00:00
abstract:INTRODUCTION:In Parkinson's disease (PD), a resting tremor of the thumb may affect the flexor pollicis longus (FPL) and influence hand functions. We investigated the relationship between FPL tendon thickness and hand function in PD patients and compared these characteristics with those in healthy controls. METHODS:The...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2016-0004
更新日期:2016-02-19 00:00:00
abstract::An 85-year-old female suffered pelvic fracture, multiple rib fractures, right hemopneumothorax, and blunt abdominal aortic injury in a traffic accident. After transfer to our hospital, transcatheter arterial embolization (TAE) was performed immediately for hemorrhage from the bilateral internal iliac arteries. Enhance...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2018-0031
更新日期:2018-05-24 00:00:00
abstract::Long non-coding RNA forkhead box D2 adjacent opposite strand RNA 1 (FOXD2-AS1) has emerged as a potential oncogene in several tumors. However, its biological function and potential regulatory mechanism in glioma have not been fully investigated to date. In the present study, RT-qPCR was conducted to detect the levels ...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2020-0175
更新日期:2020-09-30 00:00:00
abstract::An intact hepatic artery is the gateway to successful hepato-biliary surgery. Introduction of laproscopic cholecystectomy (LC) has stimulated a renewed interest in the anatomy of hepatic artery. In this case report we have highlighted importance of variations of right hepatic artery in terms of origin and course We pr...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2015-0090
更新日期:2015-12-17 00:00:00
abstract::We aimed to investigate the CXCL13 concentration of the serum and cerebral spinal fluid (CSF) in human immunodeficiency virus (HIV)-negative latent syphilis patients with treatment failure and explore the change in CXCL13 after treatment. Sixty-eight latent syphilis patients with treatment failure (failure group), 68 ...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2020-0204
更新日期:2020-07-10 00:00:00
abstract:Background:Numbers of the elderly have been on a steady increase both in Poland and other countries of the world. As they age, their health declines and they need help with their housekeeping. This, coupled with the transformation of intergenerational into single-generation or nuclear family structures, causes a marked...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2019-0035
更新日期:2019-04-24 00:00:00
abstract::The purpose of this study was to examine the efficacy rendered with a single dose of live attenuated measles, rubella, mumps, and varicella containing vaccine. We inoculated healthcare workers (HCWs) with a single dose of vaccine to a disease lacking in antibody titer for those not meeting the criteria of our hospital...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2016-0085
更新日期:2016-11-26 00:00:00
abstract::One of the most dangerous cancers in humans is Melanoma. However, early detection of melanoma can help us to cure it completely. This paper presents a new efficient method to detect malignancy in melanoma via images. At first, the extra scales are eliminated by using edge detection and smoothing. Afterwards, the propo...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2018-0002
更新日期:2018-03-15 00:00:00
abstract:Aim:To compare the clinical effectiveness of the two most commonly used LMWHs, dalteparin (DALT) and enoxaparin (ENOX), in thromboprophylaxis of elective total hip replacement (THR) or total knee replacement (TKR). Material and methods:To the prospective, randomized study were included 66 adult patients qualified to u...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2020-0213
更新日期:2020-10-12 00:00:00
abstract::Previous studies indicated that chromosome 9 translocations are involved in reduced male fertility and increased chance of miscarriage in the female partner. The aim of this study was to review the clinical features and genetic counselling requirements of infertile men carrying chromosome 9 translocations. This study ...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2019-0100
更新日期:2019-11-10 00:00:00
abstract:Background:Many factors contribute to successful nerve reconstruction. The correct technique of anastomosis is one of the key elements that determine the final result of a surgery. The aim of this study is to examine how useful an electromyography (EMG) can be as an objective intraoperative anastomosis assessment metho...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2020-0143
更新日期:2020-06-13 00:00:00
abstract::The chief aim of this study was to analyze secondary healthcare providers' efficiency, focusing on the efficiency analysis of Slovene general hospitals. We intended to present a complete picture of technical, allocative, and cost or economic efficiency of general hospitals. METHODS:We researched the aspects of effici...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2017-0031
更新日期:2017-07-06 00:00:00
abstract:Background:Cardiac arrest related to nerve blockade using a local anaesthetic is a rare event. We report a case of bupivacaine severe cardiovascular toxicity following cervical paravertebral nerve block. Case presentation:A 44-year-old female was admitted to Republican Vilnius University Hospital, with symptoms of sus...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2019-0112
更新日期:2019-12-17 00:00:00
abstract::Prostate cancer (PCa) is the second most diagnosed cancer in Western male population. In this study, we insert mK5 (the mutational kringle5 of human plasminogen) into a DD3-promoted (differential display code 3) oncolytic adenovirus to construct OncoAd.mK5.DD3. E1A.dE1B, briefly, OAd.DD3.mK5. DD3 is one of the most pr...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2019-0001
更新日期:2018-12-24 00:00:00
abstract:Background:Long noncoding RNA (lncRNA) LINC00152 (CYTOR) has been reported to be upregulated and to serve as a diagnostic biomarker in multiple types of cancers, including laryngeal squamous cell cancer (LSCC). However, the functional role and molecular mechanisms of LINC00152 in LSCC progression need to be further inv...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2020-0035
更新日期:2020-03-26 00:00:00
abstract:Objective:To observe and analyze the effect of color doppler ultrasonography (CDU) in uterine arterial embolization (UAE). Methods:160 cases of patients with uterine fibroid were selected in this study. CDU were performed on all patients before UAE as well as 5-9 days and 3-6 months after UAE, so as to observe the sha...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2017-0069
更新日期:2017-12-29 00:00:00
abstract::In this study, an effective means for detecting cancer region through different types of medical image segmentation are presented and explained. We proposed a new method for cancer segmentation on the basis of fuzzy entropy with a level set (FELs) thresholding. The proposed method was successfully utilized to segment ...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2018-0056
更新日期:2018-09-08 00:00:00
abstract::Performing accurate diagnosis using computed tomography (CT) in emergency medicine may reduce mortality rates in various diseases. In this observational, correlational and cross-sectional study, we conducted multiple regression analyses to investigate the relationship between CT utilization rates and mortality. In add...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2018-0058
更新日期:2018-09-14 00:00:00
abstract::This study evaluates the efficacy and safety of bevacizumab (BEV) in the treatment of non-small cell lung cancer (NSCLC) patients with brain metastases (BM) by performing meta-analyses of response and survival indices. Seventeen studies were included. BEV treatment was associated with a lower new BM incidence (hazard ...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2020-0192
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVE:The optimal diagnostics and treatment of acute appendicitis continues to be a challenge. A false positive diagnosis of appendicitis may lead to an unnecessary operation, which has been appropriately termed negative appendectomy. The aim of our study was to identify the effectiveness of preoperative investigat...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2016-0045
更新日期:2016-07-22 00:00:00
abstract::The large epidemiological studies demonstrated that atrial fibrillation is correlated with high mortality and adverse events in patients with acute myocardial infarction. The aim of this study was to determinate predictors of atrial fibrillation develop during the hospital period in patients with acute myocardial infa...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2017-0018
更新日期:2017-05-02 00:00:00
abstract::Three-dimensional (3D) cell cultures were created with the use of fur keratin associated proteins (F-KAPs) as scaffolds. The procedure of preparation F-KAP involves combinations of chemical activation and enzymatic digestion. The best result in porosity and heterogeneity of F-KAP surface was received during pepsin dig...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2020-0031
更新日期:2020-04-03 00:00:00
abstract::There are many determinants of vancomycin clearance, but these have not been analyzed separately in populations with different levels of renal function, which could be why some important factors have been missed. The aim of our study was to compare the pharmacokinetic parameters and factors that may affect vancomycin ...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2018-0068
更新日期:2018-10-22 00:00:00
abstract::The international plastination phenomenon has proved to be immensely popular with audiences world-wide. Never before has the human body been exposed to public gaze in such an accessible manner. The exhibitions have perplexed many, included anatomists, some of whom find the display of human bodies unethical. The object...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2016-0095
更新日期:2016-12-16 00:00:00
abstract::Responsibility means responding to the damaging consequences of technical work and in this binding perspective the general principles of guilt in genetic diagnostics and related activities are not different from any other medical performance. Performing a genetic test however, especially when it has predictive charact...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2018-0046
更新日期:2018-08-24 00:00:00
abstract::Pulmonary Langerhans Cell Histiocytosis (PLCH) is a rare disease. From the insidious onset and nonspecific manifestations, it is difficult to diagnose PLCH. To help improve the diagnosis and therapy options of adult PLCH, we present this case report and literature review about a confusing case of PLCH. In this report,...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2016-0034
更新日期:2016-06-15 00:00:00
abstract::The most undesired complication of renal angiomyolipoma (AML) is bleeding. Because of tumor rupture, the bleeding can spread to the retroperitoneal field and can be severe enough to be life threatening. We report a case of retroperitoneal hemorrhage caused by a ruptured AML that was successfully treated with transarte...
journal_title:Open medicine (Warsaw, Poland)
pub_type:
doi:10.1515/med-2015-0035
更新日期:2015-04-02 00:00:00
abstract:Background and aim:To explore the diagnostic value of recombinant heparin-binding hemagglutinin adhesin (HBHA) protein antigen in spinal tuberculosis. Materials and methods:Forty patients with spinal tuberculosis were included in the experimental group and 40 healthy people were included in the control group. Serum Ig...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2020-0017
更新日期:2020-02-28 00:00:00
abstract::To investigate the safety and efficacy of laparoscopic splenectomy and portaazygous devascularization, we studied laparoscopic splenectomy and porto-azygos devascularization patients within the peri-operative period. Clinical data and curative effect are detailed alongside statistical analysis. The laparoscopic splene...
journal_title:Open medicine (Warsaw, Poland)
pub_type: 杂志文章
doi:10.1515/med-2015-0073
更新日期:2015-12-17 00:00:00