Clinical Features of Infertile Men Carrying a Chromosome 9 Translocation.

Abstract:

:Previous studies indicated that chromosome 9 translocations are involved in reduced male fertility and increased chance of miscarriage in the female partner. The aim of this study was to review the clinical features and genetic counselling requirements of infertile men carrying chromosome 9 translocations. This study analyzed fertile-age male carriers of chromosome 9 translocations, and included 12 clinical cases in our hospital. In our cases, three cases had oligozoospermia or severe oligozoospermia, while nine cases had normal semen. Of the latter nine cases, seven were associated with recurrent spontaneous abortions, and two produced a phenotypically normal child as confirmed by amniocentesis. Male chromosome 9 translocations and specific breakpoints from reported papers were searched using PubMed and CNKI database. A literature review identified 76 male patients who carried chromosome 9 translocations. Breakpoints at 9p12, 9p11, 9p10 and 9q34.1 were related to pregestational infertility, while breakpoints at 9p21, 9q10, 9q11, 9q13, 9q21.1, 9q22, 9q22.2, 9q22.3, 9q34, 9q34.2 and 9q34.3 exhibited gestational infertility. Chromosome translocations involving chromosome 9 lead to increased risk of miscarriage. Carriers of chromosome 9 translocations should be counselled to consider in vitro fertilization accompanied by preimplantation genetic diagnosis.

journal_name

Open Med (Wars)

authors

Wang R,Yu Y,Wang Q,Jiang Y,Li L,Zhu H,Liu R,Zhang H

doi

10.1515/med-2019-0100

subject

Has Abstract

pub_date

2019-11-10 00:00:00

pages

854-862

issn

2391-5463

pii

med-2019-0100

journal_volume

14

pub_type

杂志文章
  • Differentiation of Pontine Infarction by Size.

    abstract:Purpose:We hypothesized that the current criteria may be unsuitable for lacunar pontine infarctions (LPI) diagnosis and that size criteria may indicate different stroke mechanisms. Methods:A total of 102 patients with isolated pontine infarctions were divided into a parent artery disease (PAD) and non-PAD groups accor...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2020-0025

    authors: Yang L,Qin W,Li Y,Yang S,Gu H,Hu W

    更新日期:2020-03-08 00:00:00

  • Color Doppler Ultrasound in Uterine Arterial Embolization.

    abstract:Objective:To observe and analyze the effect of color doppler ultrasonography (CDU) in uterine arterial embolization (UAE). Methods:160 cases of patients with uterine fibroid were selected in this study. CDU were performed on all patients before UAE as well as 5-9 days and 3-6 months after UAE, so as to observe the sha...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2017-0069

    authors: Jinhe R

    更新日期:2017-12-29 00:00:00

  • Serum AFU, 5'-NT and AFP as Biomarkers for Primary Hepatocellular Carcinoma Diagnosis.

    abstract::To evaluate the clinical value of serum α-L-fucosidase (AFU), 5'-nucleotidase (5'-NT) and alpha fetoprotein (AFP) as biomarkers for primary hepatocellular carcinoma (PHC) diagnosis. METHODS:Thirty six primary hepatocellular carcinoma (PHC) patients and 36 healthy controls were recruited in this study from February 20...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2017-0051

    authors: Junna Z,Gongde C,Jinying X,Xiu Z

    更新日期:2017-10-11 00:00:00

  • Thresholding for Medical Image Segmentation for Cancer using Fuzzy Entropy with Level Set Algorithm.

    abstract::In this study, an effective means for detecting cancer region through different types of medical image segmentation are presented and explained. We proposed a new method for cancer segmentation on the basis of fuzzy entropy with a level set (FELs) thresholding. The proposed method was successfully utilized to segment ...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2018-0056

    authors: Maolood IY,Al-Salhi YEA,Lu S

    更新日期:2018-09-08 00:00:00

  • Laparoscopic splenectomy and porto-azygos disconnection: clinical research in the treatment of portal hypertension.

    abstract::To investigate the safety and efficacy of laparoscopic splenectomy and portaazygous devascularization, we studied laparoscopic splenectomy and porto-azygos devascularization patients within the peri-operative period. Clinical data and curative effect are detailed alongside statistical analysis. The laparoscopic splene...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2015-0073

    authors: Fengyong W,Yuanshui S,Zhangbing,Yuewu W,Weihua Z,Jianfeng S,Qi W,Jinming L,Ji X,Zaiyuan Y

    更新日期:2015-12-17 00:00:00

  • Clinical significance and potential mechanisms of miR-223-3p and miR-204-5p in squamous cell carcinoma of head and neck: a study based on TCGA and GEO.

    abstract:Objective:To explore the clinical significance and mechanisms of altered miRNAs in squamous cell carcinoma of head and neck (SCCHN) and provide references for SCCHN diagnosis and prognosis. Method:Differential expressed miRNAs (DEMs) in SCCHN were screened through gene expression omnibus (GEO) DataSets and verified by...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2020-0146

    authors: Zhao L,Tian C,Xiao E,Du J,Liang J,Chen X,Chi W

    更新日期:2020-08-03 00:00:00

  • MicroRNA-181a-5p Regulates Inflammatory Response of Macrophages in Sepsis.

    abstract::The aim of this study was to evaluate the role of miR-181a-5p in sepsis, and to further explore the molecular mechanism. RAW 264.7 cells were stimulated with 1 μg/ml LPS for 4 hours. Firstly, qRT-PCR and ELISA was adopted to evaluate the expression of miR-181a-5p and p ro-inflammatory cytokines in RAW 264.7 macrophage...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2019-0106

    authors: Huang Z,Xu H

    更新日期:2019-11-20 00:00:00

  • Comparison of low-molecular-weight heparins in thromboprophylaxis of major orthopaedic surgery - randomized, prospective pilot study.

    abstract:Aim:To compare the clinical effectiveness of the two most commonly used LMWHs, dalteparin (DALT) and enoxaparin (ENOX), in thromboprophylaxis of elective total hip replacement (THR) or total knee replacement (TKR). Material and methods:To the prospective, randomized study were included 66 adult patients qualified to u...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2020-0213

    authors: Biławicz J,Lipa M,Wielgos M

    更新日期:2020-10-12 00:00:00

  • Pituitary Dysfunction from an Unruptured Ophthalmic Internal Carotid Artery Aneurysm with Improved 2-year Follow-up Results: A Case Report.

    abstract::Internal carotid artery (ICA) supraclinoid segment aneurysms extending into the sellar region and leading to pituitary dysfunction are a rare occurrence. To date, long-term follow up of pituitary function 2 years post-treatment has never been reported. Herein, we present a case of pituitary dysfunction due to an unrup...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2018-0021

    authors: Qi M,Ye M,Li M,Zhang P

    更新日期:2018-04-18 00:00:00

  • Galen Vein Aneurysm- Challenge for Treatment.

    abstract::The term vein of Galen aneurysm is related to a group of different vascular anomalies, with one common distinction being the dilatation of the vein of Galen. It represents a rear vascular anomaly, whose incidence is yet unknown, although some authors suggest numbers around 1:25000 deliveries. It accounts for only 1% o...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2017-0054

    authors: Crnogorac S,Bozaric AV

    更新日期:2017-12-05 00:00:00

  • The Melanin-concentrating Hormone System in Human, Rodent and Avian Brain.

    abstract::Melanin-concentrating hormone (MCH) is a cyclic 19 amino acid orexigenic hypothalamic peptide. MCH is located in the lateral and dorsal hypothalamus, as well as in the zona incerta. In mammals MCH increases food intake, contributes to regulation of energy balance, temperature, reproductive function, endocrine homeosta...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2018-0040

    authors: Bencze J,Pocsai K,Murnyák B,Gergely PA,Juhász B,Szilvássy Z,Hortobágyi T

    更新日期:2018-07-06 00:00:00

  • Abnormal right hepatic artery injury resulting in right hepatic atrophy: diagnosed by laparoscopic cholecystectomy.

    abstract::An intact hepatic artery is the gateway to successful hepato-biliary surgery. Introduction of laproscopic cholecystectomy (LC) has stimulated a renewed interest in the anatomy of hepatic artery. In this case report we have highlighted importance of variations of right hepatic artery in terms of origin and course We pr...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2015-0090

    authors: Martino V,Ferrarese A,Bindi M,Marola S,Gentile V,Rivelli M,Ferrara Y,Enrico S,Berti S,Solej M

    更新日期:2015-12-17 00:00:00

  • Prostate Cancer-Specific of DD3-driven Oncolytic Virus-harboring mK5 Gene.

    abstract::Prostate cancer (PCa) is the second most diagnosed cancer in Western male population. In this study, we insert mK5 (the mutational kringle5 of human plasminogen) into a DD3-promoted (differential display code 3) oncolytic adenovirus to construct OncoAd.mK5.DD3. E1A.dE1B, briefly, OAd.DD3.mK5. DD3 is one of the most pr...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2019-0001

    authors: Hao J,Xie W,Li H,Li R

    更新日期:2018-12-24 00:00:00

  • Genetic Testing and Professional Responsibility: The Italian Experience.

    abstract::Responsibility means responding to the damaging consequences of technical work and in this binding perspective the general principles of guilt in genetic diagnostics and related activities are not different from any other medical performance. Performing a genetic test however, especially when it has predictive charact...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2018-0046

    authors: Bin P,Conti A,Capasso E,Fedeli P,Ceccarelli P,Policino F,Casella C,Delbon P

    更新日期:2018-08-24 00:00:00

  • Urgent arterial embolization of ruptured renal angiomyolipoma.

    abstract::The most undesired complication of renal angiomyolipoma (AML) is bleeding. Because of tumor rupture, the bleeding can spread to the retroperitoneal field and can be severe enough to be life threatening. We report a case of retroperitoneal hemorrhage caused by a ruptured AML that was successfully treated with transarte...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type:

    doi:10.1515/med-2015-0035

    authors: Kervancioglu S,Yilmaz F

    更新日期:2015-04-02 00:00:00

  • Learning curve for endorectal ultrasound in young and elderly: lights and shades.

    abstract::Aim of the study is to highlight difficulties faced by an inexperienced surgeon in approaching endorectal-ultrasound, trying to define when learning curve can be considered complete. A prospective analysis was conducted on endorectal-ultrasound performed for subperitoneal rectal adenocarcinoma staging in the period fr...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2016-0074

    authors: Surace A,Ferrarese A,Gentile V,Bindi M,Cumbo J,Solej M,Enrico S,Martino V

    更新日期:2016-11-19 00:00:00

  • Integration of human papillomavirus type 16 in cervical cancer cells.

    abstract::Cervical cancer remains an important cause of women morbidity and mortality. The progression of cervical pathology correlates with the HPV integration into the host genome. However, the data on the viral integration status in cervical dysplasias are controversial. The aim of the current study was to evaluate the statu...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2015-0001

    authors: Gudleviciene Z,Kanopiene D,Stumbryte A,Bausyte R,Kirvelaitis E,Simanaviciene V,Zvirbliene A

    更新日期:2014-09-25 00:00:00

  • Measuring Efficiency of Secondary Healthcare Providers in Slovenia.

    abstract::The chief aim of this study was to analyze secondary healthcare providers' efficiency, focusing on the efficiency analysis of Slovene general hospitals. We intended to present a complete picture of technical, allocative, and cost or economic efficiency of general hospitals. METHODS:We researched the aspects of effici...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2017-0031

    authors: Blatnik P,Bojnec Š,Tušak M

    更新日期:2017-07-06 00:00:00

  • Relationship of HS CRP and Sacroiliac Joint Inflammation in Undifferentiated Spondyloarthritis.

    abstract:Objective:Elevation of serum high sensitivity C-reactive protein (hs-CRP) level has been demonstrated as a risk factor for varying diseases, as well as a biomarker for predicting recovery after operation of lumber disc herniation. Our objective was to investigate the relationship between serum hs-CRP and sacroiliac (SI...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2018-0018

    authors: Liu TJ,Chang CC,Chen LC,Chu HY,Hsu CS,Chang ST

    更新日期:2018-05-19 00:00:00

  • Intraosseous Lipoma of the Mandibula: A Case Report and Review of the Literature.

    abstract::Lipoma is a benign tumour originating from mature adipose tissue. It can occur in any place in the body where adipose tissue is located. Intraosseous lipoma is a very rare bone tumour. The authors present an infrequent case involving intraosseous lipoma of the mandible in a 32-year old man and provide a review of case...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2017-0008

    authors: Waśkowska J,Wójcik S,Koszowski R,Drozdzowska B

    更新日期:2017-03-29 00:00:00

  • A Hybrid Neural Network - World Cup Optimization Algorithm for Melanoma Detection.

    abstract::One of the most dangerous cancers in humans is Melanoma. However, early detection of melanoma can help us to cure it completely. This paper presents a new efficient method to detect malignancy in melanoma via images. At first, the extra scales are eliminated by using edge detection and smoothing. Afterwards, the propo...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2018-0002

    authors: Razmjooy N,Sheykhahmad FR,Ghadimi N

    更新日期:2018-03-15 00:00:00

  • Successful Endovascular Therapy in an Elderly Patient with Severe Hemorrhage Caused by Traumatic Injury.

    abstract::An 85-year-old female suffered pelvic fracture, multiple rib fractures, right hemopneumothorax, and blunt abdominal aortic injury in a traffic accident. After transfer to our hospital, transcatheter arterial embolization (TAE) was performed immediately for hemorrhage from the bilateral internal iliac arteries. Enhance...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2018-0031

    authors: Murata M,Aoki M,Hagiwara S,Sekihara M,Kohri T,Shibuya K,Koike N,Miyazaki D,Oshima K

    更新日期:2018-05-24 00:00:00

  • Meta-analysis of PET/CT Detect Lymph Nodes Metastases of Cervical Cancer.

    abstract:Objective:The aim of this study was to assess the diagnostic value of PET/CT for metastatic lymph nodes in cervical cancer patients. Methods:Searching in the databases including PubMed, Embase, Web of Science, Cochrane Library and Google Scholar about non-invasive modalities for detecting lymph nodes metastases during...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2018-0065

    authors: Ruan J,Zhang Y,Ren H

    更新日期:2018-09-22 00:00:00

  • Pharmacokinetics of Vancomycin in Patients with Different Renal Function Levels.

    abstract::There are many determinants of vancomycin clearance, but these have not been analyzed separately in populations with different levels of renal function, which could be why some important factors have been missed. The aim of our study was to compare the pharmacokinetic parameters and factors that may affect vancomycin ...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2018-0068

    authors: Zaric RZ,Milovanovic J,Rosic N,Milovanovic D,Zecevic DR,Folic M,Jankovic S

    更新日期:2018-10-22 00:00:00

  • FPL tendon thickness, tremor and hand functions in Parkinson's disease.

    abstract:INTRODUCTION:In Parkinson's disease (PD), a resting tremor of the thumb may affect the flexor pollicis longus (FPL) and influence hand functions. We investigated the relationship between FPL tendon thickness and hand function in PD patients and compared these characteristics with those in healthy controls. METHODS:The...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2016-0004

    authors: Toktas H,Dundar U,Kusbeci ÖY,Ulasli AM,Toy O,Oruc S

    更新日期:2016-02-19 00:00:00

  • Benefits of Computed Tomography in Reducing Mortality in Emergency Medicine.

    abstract::Performing accurate diagnosis using computed tomography (CT) in emergency medicine may reduce mortality rates in various diseases. In this observational, correlational and cross-sectional study, we conducted multiple regression analyses to investigate the relationship between CT utilization rates and mortality. In add...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2018-0058

    authors: Imai S,Akahane M,Konishi Y,Imamura T

    更新日期:2018-09-14 00:00:00

  • CXCL13 concentration in latent syphilis patients with treatment failure.

    abstract::We aimed to investigate the CXCL13 concentration of the serum and cerebral spinal fluid (CSF) in human immunodeficiency virus (HIV)-negative latent syphilis patients with treatment failure and explore the change in CXCL13 after treatment. Sixty-eight latent syphilis patients with treatment failure (failure group), 68 ...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2020-0204

    authors: Zhang Y,Wang J,Wei Y,Liu H,Wu C,Qu B,Yan Y

    更新日期:2020-07-10 00:00:00

  • Electromyography as an intraoperative test to assess the quality of nerve anastomosis - experimental study on rats.

    abstract:Background:Many factors contribute to successful nerve reconstruction. The correct technique of anastomosis is one of the key elements that determine the final result of a surgery. The aim of this study is to examine how useful an electromyography (EMG) can be as an objective intraoperative anastomosis assessment metho...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2020-0143

    authors: Czapla N,Bargiel P,Petriczko J,Kotrych D,Krajewski P,Prowans P

    更新日期:2020-06-13 00:00:00

  • A review of current progress in triple-negative breast cancer therapy.

    abstract::Triple-negative breast cancer (TNBC) is a particularly aggressive subtype known for its extremely high drug resistance, progression, poor prognosis, and lack of clear therapeutic targets. Researchers are aiming to advance TNBC treatment worldwide. In the past 2-3 years, more positive results have emerged in the clinic...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章,评审

    doi:10.1515/med-2020-0138

    authors: Shen M,Pan H,Chen Y,Xu YH,Yang W,Wu Z

    更新日期:2020-11-14 00:00:00

  • Expression and clinical significance of LXRα and SREBP-1c in placentas of preeclampsia.

    abstract:OBJECTIVE:To evaluate the expression and correlations of liver X receptor alpha (LXRa) and its target gene sterol regulatory element-binding protein-1c (SREBP-1c) in placentas of preeclampsia (PE) and their significance in PE. METHODS:Pregnancies were divided into two groups, 60 cases (29 cases of mild and 31 cases of...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章,评审

    doi:10.1515/med-2016-0057

    authors: Jianhua L,Xueqin M,Jifen H

    更新日期:2016-08-13 00:00:00