Differences of plasma IL-1 and TNF-α in healthy Chinese Population.

Abstract:

:Pleiotropic proinflammatory cytokines, interleukin- 1 (IL-1) and tumor necrosis factor-α (TNF-α), involved in the regulations of various immune responses, inflammatory processes and hematopoiesis. In the present study, the expression levels of IL-1 and TNF-α were detected by enzyme-linked immunosorbent assay (ELISA). Following the cytokine blockade as a successful clinical therapy for autoimmune diseases such as rheumatoid arthritis, the patients are more susceptible to a variety of opportunistic infections. IL-1 and TNF-α may be useful predictive biomarkers of diseases and offer potential targets for therapeutic intervention of inflammatory diseases. However, our results showed that the plasma IL-1 level was significantly higher in women compared to men (69.5 ± 19.8 pg/ml in men and 80.1 ± 19.5 pg/ml in women, respectively); the plasma levels of TNF-α were higher in men than women (20.8 ± 4.9 pg/ml and 18.7 ± 7.1 pg/ml, respectively). The significant gender difference of plasma interleukin-1 (IL-1) and TNF-α levels present in healthy adults in Jiangsu Province, China (P=0.002 and P=0.015, respectively), and may be as a hint for sex differences of susceptibility to many diseases and elementary immune response.

journal_name

Open Med (Wars)

authors

Yuan J,Wang L,Lin Y,Chen J,Hu J

doi

10.1515/med-2015-0044

subject

Has Abstract

pub_date

2015-06-09 00:00:00

pages

306-310

issue

1

issn

2391-5463

pii

med-2015-0044

journal_volume

10

pub_type

杂志文章
  • Strength and aerobic training in overweight females in Gdansk, Poland.

    abstract::We compared the effects of 16-week-training on rest metabolic rate, aerobic power, and body fat, and the post-exercise effects upon rest oxygen uptake and respiratory exchange ratio in overweight middle-aged females. Twenty nine overweight women (BMI 29.9 ± 1.2 kg*m-2) participated in training (3 days a week). The sub...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2015-0021

    authors: Sawczyn S,Mishchenko V,Moska W,Sawczyn M,Jagiełło M,Kuehne T,Kostrzewa-Nowak D,Nowak R,Cięszczyk P

    更新日期:2015-02-02 00:00:00

  • LncRNA LINC00152 Promotes Laryngeal Cancer Progression by Sponging MiR-613.

    abstract:Background:Long noncoding RNA (lncRNA) LINC00152 (CYTOR) has been reported to be upregulated and to serve as a diagnostic biomarker in multiple types of cancers, including laryngeal squamous cell cancer (LSCC). However, the functional role and molecular mechanisms of LINC00152 in LSCC progression need to be further inv...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2020-0035

    authors: Zheng X,Dong S,Sun L,Xu J,Liu J,Hao R

    更新日期:2020-03-26 00:00:00

  • FPL tendon thickness, tremor and hand functions in Parkinson's disease.

    abstract:INTRODUCTION:In Parkinson's disease (PD), a resting tremor of the thumb may affect the flexor pollicis longus (FPL) and influence hand functions. We investigated the relationship between FPL tendon thickness and hand function in PD patients and compared these characteristics with those in healthy controls. METHODS:The...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2016-0004

    authors: Toktas H,Dundar U,Kusbeci ÖY,Ulasli AM,Toy O,Oruc S

    更新日期:2016-02-19 00:00:00

  • A confusing case report of pulmonary langerhans cell histiocytosis and literature review.

    abstract::Pulmonary Langerhans Cell Histiocytosis (PLCH) is a rare disease. From the insidious onset and nonspecific manifestations, it is difficult to diagnose PLCH. To help improve the diagnosis and therapy options of adult PLCH, we present this case report and literature review about a confusing case of PLCH. In this report,...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2016-0034

    authors: Li Y,Zhen W,Costable U,Jun X,Zhe R,YuPing M

    更新日期:2016-06-15 00:00:00

  • Urgent arterial embolization of ruptured renal angiomyolipoma.

    abstract::The most undesired complication of renal angiomyolipoma (AML) is bleeding. Because of tumor rupture, the bleeding can spread to the retroperitoneal field and can be severe enough to be life threatening. We report a case of retroperitoneal hemorrhage caused by a ruptured AML that was successfully treated with transarte...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type:

    doi:10.1515/med-2015-0035

    authors: Kervancioglu S,Yilmaz F

    更新日期:2015-04-02 00:00:00

  • Genetic Testing and Professional Responsibility: The Italian Experience.

    abstract::Responsibility means responding to the damaging consequences of technical work and in this binding perspective the general principles of guilt in genetic diagnostics and related activities are not different from any other medical performance. Performing a genetic test however, especially when it has predictive charact...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2018-0046

    authors: Bin P,Conti A,Capasso E,Fedeli P,Ceccarelli P,Policino F,Casella C,Delbon P

    更新日期:2018-08-24 00:00:00

  • Laparoscopic splenectomy and porto-azygos disconnection: clinical research in the treatment of portal hypertension.

    abstract::To investigate the safety and efficacy of laparoscopic splenectomy and portaazygous devascularization, we studied laparoscopic splenectomy and porto-azygos devascularization patients within the peri-operative period. Clinical data and curative effect are detailed alongside statistical analysis. The laparoscopic splene...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2015-0073

    authors: Fengyong W,Yuanshui S,Zhangbing,Yuewu W,Weihua Z,Jianfeng S,Qi W,Jinming L,Ji X,Zaiyuan Y

    更新日期:2015-12-17 00:00:00

  • Can Keratin Scaffolds be used for Creating Three-dimensional Cell Cultures?

    abstract::Three-dimensional (3D) cell cultures were created with the use of fur keratin associated proteins (F-KAPs) as scaffolds. The procedure of preparation F-KAP involves combinations of chemical activation and enzymatic digestion. The best result in porosity and heterogeneity of F-KAP surface was received during pepsin dig...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2020-0031

    authors: Bochynska-Czyz M,Redkiewicz P,Kozlowska H,Matalinska J,Konop M,Kosson P

    更新日期:2020-04-03 00:00:00

  • Pituitary Dysfunction from an Unruptured Ophthalmic Internal Carotid Artery Aneurysm with Improved 2-year Follow-up Results: A Case Report.

    abstract::Internal carotid artery (ICA) supraclinoid segment aneurysms extending into the sellar region and leading to pituitary dysfunction are a rare occurrence. To date, long-term follow up of pituitary function 2 years post-treatment has never been reported. Herein, we present a case of pituitary dysfunction due to an unrup...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2018-0021

    authors: Qi M,Ye M,Li M,Zhang P

    更新日期:2018-04-18 00:00:00

  • CXCL13 concentration in latent syphilis patients with treatment failure.

    abstract::We aimed to investigate the CXCL13 concentration of the serum and cerebral spinal fluid (CSF) in human immunodeficiency virus (HIV)-negative latent syphilis patients with treatment failure and explore the change in CXCL13 after treatment. Sixty-eight latent syphilis patients with treatment failure (failure group), 68 ...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2020-0204

    authors: Zhang Y,Wang J,Wei Y,Liu H,Wu C,Qu B,Yan Y

    更新日期:2020-07-10 00:00:00

  • Erratum to "Suffering from Cerebral Small Vessel Disease with and without Metabolic Syndrome".

    abstract::[This corrects the article on p. 479 in vol. 14, PMID: 31231684.]. ...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 已发布勘误

    doi:10.1515/med-2021-0006

    authors: Tb M,G T,A G,D A

    更新日期:2020-11-27 00:00:00

  • Limits of Professional Competency in Nurses Working in NICU.

    abstract::Our study aimed to find out the views of nurses working in neonatal intensive care units about the limits of professional competencies and to identify situations where the limits are crossed. Methods:The research employed the focus group method. For this research we had three focus groups with nurses working in neona...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2018-0060

    authors: Skorobogatova N,Žemaitienė N,Šmigelskas K,Tamelienė R,Markūnienė E,Stonienė D

    更新日期:2018-10-04 00:00:00

  • Comparison of low-molecular-weight heparins in thromboprophylaxis of major orthopaedic surgery - randomized, prospective pilot study.

    abstract:Aim:To compare the clinical effectiveness of the two most commonly used LMWHs, dalteparin (DALT) and enoxaparin (ENOX), in thromboprophylaxis of elective total hip replacement (THR) or total knee replacement (TKR). Material and methods:To the prospective, randomized study were included 66 adult patients qualified to u...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2020-0213

    authors: Biławicz J,Lipa M,Wielgos M

    更新日期:2020-10-12 00:00:00

  • Meta-analysis of PET/CT Detect Lymph Nodes Metastases of Cervical Cancer.

    abstract:Objective:The aim of this study was to assess the diagnostic value of PET/CT for metastatic lymph nodes in cervical cancer patients. Methods:Searching in the databases including PubMed, Embase, Web of Science, Cochrane Library and Google Scholar about non-invasive modalities for detecting lymph nodes metastases during...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2018-0065

    authors: Ruan J,Zhang Y,Ren H

    更新日期:2018-09-22 00:00:00

  • Learning curve for endorectal ultrasound in young and elderly: lights and shades.

    abstract::Aim of the study is to highlight difficulties faced by an inexperienced surgeon in approaching endorectal-ultrasound, trying to define when learning curve can be considered complete. A prospective analysis was conducted on endorectal-ultrasound performed for subperitoneal rectal adenocarcinoma staging in the period fr...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2016-0074

    authors: Surace A,Ferrarese A,Gentile V,Bindi M,Cumbo J,Solej M,Enrico S,Martino V

    更新日期:2016-11-19 00:00:00

  • Abnormal right hepatic artery injury resulting in right hepatic atrophy: diagnosed by laparoscopic cholecystectomy.

    abstract::An intact hepatic artery is the gateway to successful hepato-biliary surgery. Introduction of laproscopic cholecystectomy (LC) has stimulated a renewed interest in the anatomy of hepatic artery. In this case report we have highlighted importance of variations of right hepatic artery in terms of origin and course We pr...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2015-0090

    authors: Martino V,Ferrarese A,Bindi M,Marola S,Gentile V,Rivelli M,Ferrara Y,Enrico S,Berti S,Solej M

    更新日期:2015-12-17 00:00:00

  • The Mechanism of Mitral Regurgitant Jets Identified by 3-Dimensional Transesophageal Echocardiography.

    abstract::This study is a case report, which presents a case of severe mitral regurgitation in a 77-year-old man. Two-dimensional transesophageal echocardiography (TEE), regurgitant jets directed anteriorly in early systole and centrally to laterally in late systole were seen, while three-dimensional TEE showed a flail posterio...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2018-0047

    authors: Iida R,Aono M,Choy J

    更新日期:2018-08-11 00:00:00

  • Acute chemoradiotherapy toxicity in cervical cancer patients.

    abstract::During radiotherapy treatment for cervical cancer, up to 84% of patients exhibit some form of acute radiation toxicity (ART). The primary aim of this clinical study is to determine the impact of angiotensin-converting enzyme (ACE) inhibitors, β-blockers and other risk factors such as the patient's anatomical character...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2020-0222

    authors: Radojevic MZ,Tomasevic A,Karapandzic VP,Milosavljevic N,Jankovic S,Folic M

    更新日期:2020-09-02 00:00:00

  • Benefits of Computed Tomography in Reducing Mortality in Emergency Medicine.

    abstract::Performing accurate diagnosis using computed tomography (CT) in emergency medicine may reduce mortality rates in various diseases. In this observational, correlational and cross-sectional study, we conducted multiple regression analyses to investigate the relationship between CT utilization rates and mortality. In add...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2018-0058

    authors: Imai S,Akahane M,Konishi Y,Imamura T

    更新日期:2018-09-14 00:00:00

  • Trends in the treatment of risk factors for stroke in a Czech stroke unit.

    abstract::The goal of this study is to evaluate therapeutic trends for several diseases that represent risk factors for stroke. The relative frequency of therapy with compounds that influence the risk factors for stroke was monitored in a group of 3,290 patients who were hospitalised in the Stroke Unit at the University Hospita...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2015-0060

    authors: Simunek L,Krajickova D,Vysata O,Valis M

    更新日期:2015-10-26 00:00:00

  • Electromyography as an intraoperative test to assess the quality of nerve anastomosis - experimental study on rats.

    abstract:Background:Many factors contribute to successful nerve reconstruction. The correct technique of anastomosis is one of the key elements that determine the final result of a surgery. The aim of this study is to examine how useful an electromyography (EMG) can be as an objective intraoperative anastomosis assessment metho...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2020-0143

    authors: Czapla N,Bargiel P,Petriczko J,Kotrych D,Krajewski P,Prowans P

    更新日期:2020-06-13 00:00:00

  • A Hybrid Neural Network - World Cup Optimization Algorithm for Melanoma Detection.

    abstract::One of the most dangerous cancers in humans is Melanoma. However, early detection of melanoma can help us to cure it completely. This paper presents a new efficient method to detect malignancy in melanoma via images. At first, the extra scales are eliminated by using edge detection and smoothing. Afterwards, the propo...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2018-0002

    authors: Razmjooy N,Sheykhahmad FR,Ghadimi N

    更新日期:2018-03-15 00:00:00

  • Pharmacokinetics of Vancomycin in Patients with Different Renal Function Levels.

    abstract::There are many determinants of vancomycin clearance, but these have not been analyzed separately in populations with different levels of renal function, which could be why some important factors have been missed. The aim of our study was to compare the pharmacokinetic parameters and factors that may affect vancomycin ...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2018-0068

    authors: Zaric RZ,Milovanovic J,Rosic N,Milovanovic D,Zecevic DR,Folic M,Jankovic S

    更新日期:2018-10-22 00:00:00

  • Is acute appendicitis still misdiagnosed?

    abstract:OBJECTIVE:The optimal diagnostics and treatment of acute appendicitis continues to be a challenge. A false positive diagnosis of appendicitis may lead to an unnecessary operation, which has been appropriately termed negative appendectomy. The aim of our study was to identify the effectiveness of preoperative investigat...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2016-0045

    authors: Kryzauskas M,Danys D,Poskus T,Mikalauskas S,Poskus E,Jotautas V,Beisa V,Strupas K

    更新日期:2016-07-22 00:00:00

  • The diagnosis and pathological value of combined detection of HE4 and CA125 for patients with ovarian cancer.

    abstract:OBJECTIVE:To evaluate the value of individual and combined measurement of human epididymis protein 4 (HE4) and cancer antigen 125 (CA-125) in the diagnosis of ovarian cancer. METHODS:A clinical case-control study was performed in which the levels of serum HE4 and CA-125 of subjects with malignant, borderline, benign o...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2016-0024

    authors: Zheng LE,Qu JY,He F

    更新日期:2016-05-06 00:00:00

  • Measuring Efficiency of Secondary Healthcare Providers in Slovenia.

    abstract::The chief aim of this study was to analyze secondary healthcare providers' efficiency, focusing on the efficiency analysis of Slovene general hospitals. We intended to present a complete picture of technical, allocative, and cost or economic efficiency of general hospitals. METHODS:We researched the aspects of effici...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2017-0031

    authors: Blatnik P,Bojnec Š,Tušak M

    更新日期:2017-07-06 00:00:00

  • Differentiation of Pontine Infarction by Size.

    abstract:Purpose:We hypothesized that the current criteria may be unsuitable for lacunar pontine infarctions (LPI) diagnosis and that size criteria may indicate different stroke mechanisms. Methods:A total of 102 patients with isolated pontine infarctions were divided into a parent artery disease (PAD) and non-PAD groups accor...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2020-0025

    authors: Yang L,Qin W,Li Y,Yang S,Gu H,Hu W

    更新日期:2020-03-08 00:00:00

  • Expression and clinical significance of LXRα and SREBP-1c in placentas of preeclampsia.

    abstract:OBJECTIVE:To evaluate the expression and correlations of liver X receptor alpha (LXRa) and its target gene sterol regulatory element-binding protein-1c (SREBP-1c) in placentas of preeclampsia (PE) and their significance in PE. METHODS:Pregnancies were divided into two groups, 60 cases (29 cases of mild and 31 cases of...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章,评审

    doi:10.1515/med-2016-0057

    authors: Jianhua L,Xueqin M,Jifen H

    更新日期:2016-08-13 00:00:00

  • Endometrial cancer and microsatellite instability status.

    abstract::Microsatellite instability (MSI) is an important factor in the development of various cancers as an identifier of a defective DNA mismatch repair system. The objective of our study was to define the association between microsatellite instability status and traditional clinicopathologic characteristics of endometrioid ...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2015-0005

    authors: Kanopiene D,Vidugiriene J,Valuckas KP,Smailyte G,Uleckiene S,Bacher J

    更新日期:2014-11-11 00:00:00

  • Long non-coding RNA FOXD2-AS1 promotes cell proliferation, metastasis and EMT in glioma by sponging miR-506-5p.

    abstract::Long non-coding RNA forkhead box D2 adjacent opposite strand RNA 1 (FOXD2-AS1) has emerged as a potential oncogene in several tumors. However, its biological function and potential regulatory mechanism in glioma have not been fully investigated to date. In the present study, RT-qPCR was conducted to detect the levels ...

    journal_title:Open medicine (Warsaw, Poland)

    pub_type: 杂志文章

    doi:10.1515/med-2020-0175

    authors: Zhao J,Zeng XB,Zhang HY,Xiang JW,Liu YS

    更新日期:2020-09-30 00:00:00