Endometrial cancer and microsatellite instability status.

abstract：:Prostate cancer (PCa) is the second most diagnosed cancer in Western male population. In this study, we insert mK5 (the mutational kringle5 of human plasminogen) into a DD3-promoted (differential display code 3) oncolytic adenovirus to construct OncoAd.mK5.DD3. E1A.dE1B, briefly, OAd.DD3.mK5. DD3 is one of the most pr...

journal_title：Open medicine (Warsaw, Poland)

authors： Hao J,Xie W,Li H,Li R

更新日期：2018-12-24 00:00:00

abstract：:Not fully maturated immune system in preterm neonates may contribute to the increased susceptibility to infection. The levels of some cytokines can be useful in the prediction and diagnosis of sepsis in premature neonates. In the present study, we evaluated the potential predictive role of IFN-γ and IL-5 in cord and v...

journal_title：Open medicine (Warsaw, Poland)

authors： Vucic J,Vucic M,Stankovic T,Stamenkovic H,Stankovic S,Zlatanovic D

更新日期：2021-01-11 00:00:00

abstract：:Long non-coding RNA forkhead box D2 adjacent opposite strand RNA 1 (FOXD2-AS1) has emerged as a potential oncogene in several tumors. However, its biological function and potential regulatory mechanism in glioma have not been fully investigated to date. In the present study, RT-qPCR was conducted to detect the levels ...

journal_title：Open medicine (Warsaw, Poland)

authors： Zhao J,Zeng XB,Zhang HY,Xiang JW,Liu YS

更新日期：2020-09-30 00:00:00

abstract：:Melanin-concentrating hormone (MCH) is a cyclic 19 amino acid orexigenic hypothalamic peptide. MCH is located in the lateral and dorsal hypothalamus, as well as in the zona incerta. In mammals MCH increases food intake, contributes to regulation of energy balance, temperature, reproductive function, endocrine homeosta...

journal_title：Open medicine (Warsaw, Poland)

authors： Bencze J,Pocsai K,Murnyák B,Gergely PA,Juhász B,Szilvássy Z,Hortobágyi T

更新日期：2018-07-06 00:00:00

abstract：:To investigate the safety and efficacy of laparoscopic splenectomy and portaazygous devascularization, we studied laparoscopic splenectomy and porto-azygos devascularization patients within the peri-operative period. Clinical data and curative effect are detailed alongside statistical analysis. The laparoscopic splene...

journal_title：Open medicine (Warsaw, Poland)

authors： Fengyong W,Yuanshui S,Zhangbing,Yuewu W,Weihua Z,Jianfeng S,Qi W,Jinming L,Ji X,Zaiyuan Y

更新日期：2015-12-17 00:00:00

abstract：Background:Long noncoding RNA (lncRNA) LINC00152 (CYTOR) has been reported to be upregulated and to serve as a diagnostic biomarker in multiple types of cancers, including laryngeal squamous cell cancer (LSCC). However, the functional role and molecular mechanisms of LINC00152 in LSCC progression need to be further inv...

journal_title：Open medicine (Warsaw, Poland)

authors： Zheng X,Dong S,Sun L,Xu J,Liu J,Hao R

更新日期：2020-03-26 00:00:00

abstract：:During radiotherapy treatment for cervical cancer, up to 84% of patients exhibit some form of acute radiation toxicity (ART). The primary aim of this clinical study is to determine the impact of angiotensin-converting enzyme (ACE) inhibitors, β-blockers and other risk factors such as the patient's anatomical character...

journal_title：Open medicine (Warsaw, Poland)

authors： Radojevic MZ,Tomasevic A,Karapandzic VP,Milosavljevic N,Jankovic S,Folic M

更新日期：2020-09-02 00:00:00

abstract：:The aim of this study was to evaluate the role of miR-181a-5p in sepsis, and to further explore the molecular mechanism. RAW 264.7 cells were stimulated with 1 μg/ml LPS for 4 hours. Firstly, qRT-PCR and ELISA was adopted to evaluate the expression of miR-181a-5p and p ro-inflammatory cytokines in RAW 264.7 macrophage...

journal_title：Open medicine (Warsaw, Poland)

authors： Huang Z,Xu H

更新日期：2019-11-20 00:00:00

abstract：:Garengeot's hernia (GH) is defined as the presence of the appendix inside a femoral hernia. It occurs in 0.9% of femoral hernias and is usually an incidental finding during surgery. Its treatment is controversial and the aim of this article is to review the diagnostic methods and surgical considerations. We report two...

journal_title：Open medicine (Warsaw, Poland)

authors： Garcia-Amador C,De la Plaza R,Arteaga V,Lopez-Marcano A,Ramia J

更新日期：2016-10-07 00:00:00

abstract：:This study is a case report, which presents a case of severe mitral regurgitation in a 77-year-old man. Two-dimensional transesophageal echocardiography (TEE), regurgitant jets directed anteriorly in early systole and centrally to laterally in late systole were seen, while three-dimensional TEE showed a flail posterio...

journal_title：Open medicine (Warsaw, Poland)

authors： Iida R,Aono M,Choy J

更新日期：2018-08-11 00:00:00

abstract：Purpose:We hypothesized that the current criteria may be unsuitable for lacunar pontine infarctions (LPI) diagnosis and that size criteria may indicate different stroke mechanisms. Methods:A total of 102 patients with isolated pontine infarctions were divided into a parent artery disease (PAD) and non-PAD groups accor...

journal_title：Open medicine (Warsaw, Poland)

authors： Yang L,Qin W,Li Y,Yang S,Gu H,Hu W

更新日期：2020-03-08 00:00:00

abstract：Objective:To explore the clinical significance and mechanisms of altered miRNAs in squamous cell carcinoma of head and neck (SCCHN) and provide references for SCCHN diagnosis and prognosis. Method:Differential expressed miRNAs (DEMs) in SCCHN were screened through gene expression omnibus (GEO) DataSets and verified by...

journal_title：Open medicine (Warsaw, Poland)

authors： Zhao L,Tian C,Xiao E,Du J,Liang J,Chen X,Chi W

更新日期：2020-08-03 00:00:00

abstract：OBJECTIVE:To evaluate the value of individual and combined measurement of human epididymis protein 4 (HE4) and cancer antigen 125 (CA-125) in the diagnosis of ovarian cancer. METHODS:A clinical case-control study was performed in which the levels of serum HE4 and CA-125 of subjects with malignant, borderline, benign o...

journal_title：Open medicine (Warsaw, Poland)

authors： Zheng LE,Qu JY,He F

更新日期：2016-05-06 00:00:00

abstract：:An intact hepatic artery is the gateway to successful hepato-biliary surgery. Introduction of laproscopic cholecystectomy (LC) has stimulated a renewed interest in the anatomy of hepatic artery. In this case report we have highlighted importance of variations of right hepatic artery in terms of origin and course We pr...

journal_title：Open medicine (Warsaw, Poland)

authors： Martino V,Ferrarese A,Bindi M,Marola S,Gentile V,Rivelli M,Ferrara Y,Enrico S,Berti S,Solej M

更新日期：2015-12-17 00:00:00

abstract：:Our study aimed to find out the views of nurses working in neonatal intensive care units about the limits of professional competencies and to identify situations where the limits are crossed. Methods:The research employed the focus group method. For this research we had three focus groups with nurses working in neona...

journal_title：Open medicine (Warsaw, Poland)

authors： Skorobogatova N,Žemaitienė N,Šmigelskas K,Tamelienė R,Markūnienė E,Stonienė D

更新日期：2018-10-04 00:00:00

abstract：:The goal of this study is to evaluate therapeutic trends for several diseases that represent risk factors for stroke. The relative frequency of therapy with compounds that influence the risk factors for stroke was monitored in a group of 3,290 patients who were hospitalised in the Stroke Unit at the University Hospita...

journal_title：Open medicine (Warsaw, Poland)

authors： Simunek L,Krajickova D,Vysata O,Valis M

更新日期：2015-10-26 00:00:00

abstract：:One of the most dangerous cancers in humans is Melanoma. However, early detection of melanoma can help us to cure it completely. This paper presents a new efficient method to detect malignancy in melanoma via images. At first, the extra scales are eliminated by using edge detection and smoothing. Afterwards, the propo...

journal_title：Open medicine (Warsaw, Poland)

authors： Razmjooy N,Sheykhahmad FR,Ghadimi N

更新日期：2018-03-15 00:00:00

abstract：:Triple-negative breast cancer (TNBC) is a particularly aggressive subtype known for its extremely high drug resistance, progression, poor prognosis, and lack of clear therapeutic targets. Researchers are aiming to advance TNBC treatment worldwide. In the past 2-3 years, more positive results have emerged in the clinic...

journal_title：Open medicine (Warsaw, Poland)

authors： Shen M,Pan H,Chen Y,Xu YH,Yang W,Wu Z

更新日期：2020-11-14 00:00:00

abstract：:Cervical cancer remains an important cause of women morbidity and mortality. The progression of cervical pathology correlates with the HPV integration into the host genome. However, the data on the viral integration status in cervical dysplasias are controversial. The aim of the current study was to evaluate the statu...

journal_title：Open medicine (Warsaw, Poland)

authors： Gudleviciene Z,Kanopiene D,Stumbryte A,Bausyte R,Kirvelaitis E,Simanaviciene V,Zvirbliene A

更新日期：2014-09-25 00:00:00

abstract：:Responsibility means responding to the damaging consequences of technical work and in this binding perspective the general principles of guilt in genetic diagnostics and related activities are not different from any other medical performance. Performing a genetic test however, especially when it has predictive charact...

journal_title：Open medicine (Warsaw, Poland)

authors： Bin P,Conti A,Capasso E,Fedeli P,Ceccarelli P,Policino F,Casella C,Delbon P

更新日期：2018-08-24 00:00:00

abstract：Objective:To observe and analyze the effect of color doppler ultrasonography (CDU) in uterine arterial embolization (UAE). Methods:160 cases of patients with uterine fibroid were selected in this study. CDU were performed on all patients before UAE as well as 5-9 days and 3-6 months after UAE, so as to observe the sha...

journal_title：Open medicine (Warsaw, Poland)

authors： Jinhe R

更新日期：2017-12-29 00:00:00

abstract：Objective:The aim of this study was to assess the diagnostic value of PET/CT for metastatic lymph nodes in cervical cancer patients. Methods:Searching in the databases including PubMed, Embase, Web of Science, Cochrane Library and Google Scholar about non-invasive modalities for detecting lymph nodes metastases during...

journal_title：Open medicine (Warsaw, Poland)

authors： Ruan J,Zhang Y,Ren H

更新日期：2018-09-22 00:00:00

abstract：:Pleiotropic proinflammatory cytokines, interleukin- 1 (IL-1) and tumor necrosis factor-α (TNF-α), involved in the regulations of various immune responses, inflammatory processes and hematopoiesis. In the present study, the expression levels of IL-1 and TNF-α were detected by enzyme-linked immunosorbent assay (ELISA). ...

journal_title：Open medicine (Warsaw, Poland)

authors： Yuan J,Wang L,Lin Y,Chen J,Hu J

更新日期：2015-06-09 00:00:00

abstract：:Regional anaesthesia techniques in ophthalmology are usually utilized for day case surgery. During various procedures, profound akinesia of the eye and anaesthesia of the surgical site are required, both of which are achieved with retrobulbar block. Due to the anatomy of the eye, life-threatening complications are pos...

journal_title：Open medicine (Warsaw, Poland)

authors： Kostadinov I,Hostnik A,Cvenkel B,Potočnik I

更新日期：2019-03-02 00:00:00

abstract：Background:Numbers of the elderly have been on a steady increase both in Poland and other countries of the world. As they age, their health declines and they need help with their housekeeping. This, coupled with the transformation of intergenerational into single-generation or nuclear family structures, causes a marked...

journal_title：Open medicine (Warsaw, Poland)

authors： Trybusińska D,Saracen A

更新日期：2019-04-24 00:00:00

abstract：:Arginine vasopressin can bind to high-affinity vasopressin V1a receptors in human leukocytes. This study aims to investigate the effects of arginine vasopressin on migration and chemotaxis of neutrophils and oxygen free radical release by human leukocytes. Neutrophils and monocytes were obtained from peripheral blood ...

journal_title：Open medicine (Warsaw, Poland)

authors： Wiedermann FJ,Watzinger K,Stichlberger M,Joannidis M,Kaehler C,Lederer W

更新日期：2018-05-09 00:00:00

abstract：:To observe a therapeutic effect of macrolide antibiotics in children with Pseudomonas aeruginosa pneumonia. Fifty-four cases of children with Pseudomonas aeruginosa pneumonia were randomly divided into an observation group (n=30) and a control group (n=24). The observation group was treated with macrolide antibiotics ...

journal_title：Open medicine (Warsaw, Poland)

authors： Huang XQ,Deng L,Lu G,He CH,Wu PQ,Xie ZW,Ashraf MA

更新日期：2015-12-17 00:00:00

abstract：:Internal carotid artery (ICA) supraclinoid segment aneurysms extending into the sellar region and leading to pituitary dysfunction are a rare occurrence. To date, long-term follow up of pituitary function 2 years post-treatment has never been reported. Herein, we present a case of pituitary dysfunction due to an unrup...

journal_title：Open medicine (Warsaw, Poland)

authors： Qi M,Ye M,Li M,Zhang P

更新日期：2018-04-18 00:00:00

abstract：INTRODUCTION:In Parkinson's disease (PD), a resting tremor of the thumb may affect the flexor pollicis longus (FPL) and influence hand functions. We investigated the relationship between FPL tendon thickness and hand function in PD patients and compared these characteristics with those in healthy controls. METHODS:The...

journal_title：Open medicine (Warsaw, Poland)

authors： Toktas H,Dundar U,Kusbeci ÖY,Ulasli AM,Toy O,Oruc S

更新日期：2016-02-19 00:00:00

abstract：Background and aim:To explore the diagnostic value of recombinant heparin-binding hemagglutinin adhesin (HBHA) protein antigen in spinal tuberculosis. Materials and methods:Forty patients with spinal tuberculosis were included in the experimental group and 40 healthy people were included in the control group. Serum Ig...

journal_title：Open medicine (Warsaw, Poland)

authors： Pu F,Feng J,Niu F,Xia P

更新日期：2020-02-28 00:00:00