A review of current progress in triple-negative breast cancer therapy.

abstract：:The international plastination phenomenon has proved to be immensely popular with audiences world-wide. Never before has the human body been exposed to public gaze in such an accessible manner. The exhibitions have perplexed many, included anatomists, some of whom find the display of human bodies unethical. The object...

journal_title：Open medicine (Warsaw, Poland)

authors： Bin P,Conti A,Buccelli C,Addeo G,Capasso E,Piras M

更新日期：2016-12-16 00:00:00

abstract：:Long non-coding RNA forkhead box D2 adjacent opposite strand RNA 1 (FOXD2-AS1) has emerged as a potential oncogene in several tumors. However, its biological function and potential regulatory mechanism in glioma have not been fully investigated to date. In the present study, RT-qPCR was conducted to detect the levels ...

journal_title：Open medicine (Warsaw, Poland)

authors： Zhao J,Zeng XB,Zhang HY,Xiang JW,Liu YS

更新日期：2020-09-30 00:00:00

abstract：:During radiotherapy treatment for cervical cancer, up to 84% of patients exhibit some form of acute radiation toxicity (ART). The primary aim of this clinical study is to determine the impact of angiotensin-converting enzyme (ACE) inhibitors, β-blockers and other risk factors such as the patient's anatomical character...

journal_title：Open medicine (Warsaw, Poland)

authors： Radojevic MZ,Tomasevic A,Karapandzic VP,Milosavljevic N,Jankovic S,Folic M

更新日期：2020-09-02 00:00:00

abstract：Objective:To explore the clinical significance and mechanisms of altered miRNAs in squamous cell carcinoma of head and neck (SCCHN) and provide references for SCCHN diagnosis and prognosis. Method:Differential expressed miRNAs (DEMs) in SCCHN were screened through gene expression omnibus (GEO) DataSets and verified by...

journal_title：Open medicine (Warsaw, Poland)

authors： Zhao L,Tian C,Xiao E,Du J,Liang J,Chen X,Chi W

更新日期：2020-08-03 00:00:00

abstract：Aim:To compare the clinical effectiveness of the two most commonly used LMWHs, dalteparin (DALT) and enoxaparin (ENOX), in thromboprophylaxis of elective total hip replacement (THR) or total knee replacement (TKR). Material and methods:To the prospective, randomized study were included 66 adult patients qualified to u...

journal_title：Open medicine (Warsaw, Poland)

authors： Biławicz J,Lipa M,Wielgos M

更新日期：2020-10-12 00:00:00

abstract：Background:Numbers of the elderly have been on a steady increase both in Poland and other countries of the world. As they age, their health declines and they need help with their housekeeping. This, coupled with the transformation of intergenerational into single-generation or nuclear family structures, causes a marked...

journal_title：Open medicine (Warsaw, Poland)

authors： Trybusińska D,Saracen A

更新日期：2019-04-24 00:00:00

abstract：Background:Long noncoding RNA (lncRNA) LINC00152 (CYTOR) has been reported to be upregulated and to serve as a diagnostic biomarker in multiple types of cancers, including laryngeal squamous cell cancer (LSCC). However, the functional role and molecular mechanisms of LINC00152 in LSCC progression need to be further inv...

journal_title：Open medicine (Warsaw, Poland)

authors： Zheng X,Dong S,Sun L,Xu J,Liu J,Hao R

更新日期：2020-03-26 00:00:00

abstract：:We aimed to investigate the CXCL13 concentration of the serum and cerebral spinal fluid (CSF) in human immunodeficiency virus (HIV)-negative latent syphilis patients with treatment failure and explore the change in CXCL13 after treatment. Sixty-eight latent syphilis patients with treatment failure (failure group), 68 ...

journal_title：Open medicine (Warsaw, Poland)

authors： Zhang Y,Wang J,Wei Y,Liu H,Wu C,Qu B,Yan Y

更新日期：2020-07-10 00:00:00

abstract：Purpose:We hypothesized that the current criteria may be unsuitable for lacunar pontine infarctions (LPI) diagnosis and that size criteria may indicate different stroke mechanisms. Methods:A total of 102 patients with isolated pontine infarctions were divided into a parent artery disease (PAD) and non-PAD groups accor...

journal_title：Open medicine (Warsaw, Poland)

authors： Yang L,Qin W,Li Y,Yang S,Gu H,Hu W

更新日期：2020-03-08 00:00:00

abstract：:Three-dimensional (3D) cell cultures were created with the use of fur keratin associated proteins (F-KAPs) as scaffolds. The procedure of preparation F-KAP involves combinations of chemical activation and enzymatic digestion. The best result in porosity and heterogeneity of F-KAP surface was received during pepsin dig...

journal_title：Open medicine (Warsaw, Poland)

authors： Bochynska-Czyz M,Redkiewicz P,Kozlowska H,Matalinska J,Konop M,Kosson P

更新日期：2020-04-03 00:00:00

abstract：:Previous studies indicated that chromosome 9 translocations are involved in reduced male fertility and increased chance of miscarriage in the female partner. The aim of this study was to review the clinical features and genetic counselling requirements of infertile men carrying chromosome 9 translocations. This study ...

journal_title：Open medicine (Warsaw, Poland)

authors： Wang R,Yu Y,Wang Q,Jiang Y,Li L,Zhu H,Liu R,Zhang H

更新日期：2019-11-10 00:00:00

abstract：:Cervical cancer remains an important cause of women morbidity and mortality. The progression of cervical pathology correlates with the HPV integration into the host genome. However, the data on the viral integration status in cervical dysplasias are controversial. The aim of the current study was to evaluate the statu...

journal_title：Open medicine (Warsaw, Poland)

authors： Gudleviciene Z,Kanopiene D,Stumbryte A,Bausyte R,Kirvelaitis E,Simanaviciene V,Zvirbliene A

更新日期：2014-09-25 00:00:00

abstract：Background:To analyze the cardio-protective effects of ticagrelor in patients with acute coronary syndrome with S-T segment elevation. Methods:The sample was 200 patients who had been diagnosed with acute coronary syndrome accompanied by diabetes Mellitus type II. Only patients having ST segment elevation before the t...

journal_title：Open medicine (Warsaw, Poland)

authors： Li DT,Li SB,Zheng JY,Tang HH,Qiu YG,Xue N,Cao Y

更新日期：2019-02-20 00:00:00

abstract：:[This corrects the article on p. 479 in vol. 14, PMID: 31231684.]. ...

journal_title：Open medicine (Warsaw, Poland)

authors： Tb M,G T,A G,D A

更新日期：2020-11-27 00:00:00

abstract：Objective:The aim of this study was to assess the diagnostic value of PET/CT for metastatic lymph nodes in cervical cancer patients. Methods:Searching in the databases including PubMed, Embase, Web of Science, Cochrane Library and Google Scholar about non-invasive modalities for detecting lymph nodes metastases during...

journal_title：Open medicine (Warsaw, Poland)

authors： Ruan J,Zhang Y,Ren H

更新日期：2018-09-22 00:00:00

abstract：:Aim of the study is to highlight difficulties faced by an inexperienced surgeon in approaching endorectal-ultrasound, trying to define when learning curve can be considered complete. A prospective analysis was conducted on endorectal-ultrasound performed for subperitoneal rectal adenocarcinoma staging in the period fr...

journal_title：Open medicine (Warsaw, Poland)

authors： Surace A,Ferrarese A,Gentile V,Bindi M,Cumbo J,Solej M,Enrico S,Martino V

更新日期：2016-11-19 00:00:00

abstract：OBJECTIVE:The optimal diagnostics and treatment of acute appendicitis continues to be a challenge. A false positive diagnosis of appendicitis may lead to an unnecessary operation, which has been appropriately termed negative appendectomy. The aim of our study was to identify the effectiveness of preoperative investigat...

journal_title：Open medicine (Warsaw, Poland)

authors： Kryzauskas M,Danys D,Poskus T,Mikalauskas S,Poskus E,Jotautas V,Beisa V,Strupas K

更新日期：2016-07-22 00:00:00

abstract：:Microsatellite instability (MSI) is an important factor in the development of various cancers as an identifier of a defective DNA mismatch repair system. The objective of our study was to define the association between microsatellite instability status and traditional clinicopathologic characteristics of endometrioid ...

journal_title：Open medicine (Warsaw, Poland)

authors： Kanopiene D,Vidugiriene J,Valuckas KP,Smailyte G,Uleckiene S,Bacher J

更新日期：2014-11-11 00:00:00

abstract：:One of the most dangerous cancers in humans is Melanoma. However, early detection of melanoma can help us to cure it completely. This paper presents a new efficient method to detect malignancy in melanoma via images. At first, the extra scales are eliminated by using edge detection and smoothing. Afterwards, the propo...

journal_title：Open medicine (Warsaw, Poland)

authors： Razmjooy N,Sheykhahmad FR,Ghadimi N

更新日期：2018-03-15 00:00:00

abstract：:The purpose of this study was to examine the efficacy rendered with a single dose of live attenuated measles, rubella, mumps, and varicella containing vaccine. We inoculated healthcare workers (HCWs) with a single dose of vaccine to a disease lacking in antibody titer for those not meeting the criteria of our hospital...

journal_title：Open medicine (Warsaw, Poland)

authors： Ogawa T,Uchiyama-Nakamura F,Sugata-Tsubaki A,Yamada Y,Uno K,Kasahara K,Maeda K,Konishi M,Mikasa K

更新日期：2016-11-26 00:00:00

abstract：:An 85-year-old female suffered pelvic fracture, multiple rib fractures, right hemopneumothorax, and blunt abdominal aortic injury in a traffic accident. After transfer to our hospital, transcatheter arterial embolization (TAE) was performed immediately for hemorrhage from the bilateral internal iliac arteries. Enhance...

journal_title：Open medicine (Warsaw, Poland)

authors： Murata M,Aoki M,Hagiwara S,Sekihara M,Kohri T,Shibuya K,Koike N,Miyazaki D,Oshima K

更新日期：2018-05-24 00:00:00

abstract：:This study evaluates the efficacy and safety of bevacizumab (BEV) in the treatment of non-small cell lung cancer (NSCLC) patients with brain metastases (BM) by performing meta-analyses of response and survival indices. Seventeen studies were included. BEV treatment was associated with a lower new BM incidence (hazard ...

journal_title：Open medicine (Warsaw, Poland)

authors： Liang P,Wang YD,Wei ZM,Deng QJ,Xu T,Liu J,Luo N,Hou J

更新日期：2020-07-01 00:00:00

abstract：:The large epidemiological studies demonstrated that atrial fibrillation is correlated with high mortality and adverse events in patients with acute myocardial infarction. The aim of this study was to determinate predictors of atrial fibrillation develop during the hospital period in patients with acute myocardial infa...

journal_title：Open medicine (Warsaw, Poland)

authors： Vukmirović M,Bošković A,Tomašević Vukmirović I,Vujadinovic R,Fatić N,Bukumirić Z,Vukmirović F

更新日期：2017-05-02 00:00:00

abstract：Background:Many factors contribute to successful nerve reconstruction. The correct technique of anastomosis is one of the key elements that determine the final result of a surgery. The aim of this study is to examine how useful an electromyography (EMG) can be as an objective intraoperative anastomosis assessment metho...

journal_title：Open medicine (Warsaw, Poland)

authors： Czapla N,Bargiel P,Petriczko J,Kotrych D,Krajewski P,Prowans P

更新日期：2020-06-13 00:00:00

abstract：:An intact hepatic artery is the gateway to successful hepato-biliary surgery. Introduction of laproscopic cholecystectomy (LC) has stimulated a renewed interest in the anatomy of hepatic artery. In this case report we have highlighted importance of variations of right hepatic artery in terms of origin and course We pr...

journal_title：Open medicine (Warsaw, Poland)

authors： Martino V,Ferrarese A,Bindi M,Marola S,Gentile V,Rivelli M,Ferrara Y,Enrico S,Berti S,Solej M

更新日期：2015-12-17 00:00:00

abstract：:The goal of this study is to evaluate therapeutic trends for several diseases that represent risk factors for stroke. The relative frequency of therapy with compounds that influence the risk factors for stroke was monitored in a group of 3,290 patients who were hospitalised in the Stroke Unit at the University Hospita...

journal_title：Open medicine (Warsaw, Poland)

authors： Simunek L,Krajickova D,Vysata O,Valis M

更新日期：2015-10-26 00:00:00

abstract：Background:Cardiac arrest related to nerve blockade using a local anaesthetic is a rare event. We report a case of bupivacaine severe cardiovascular toxicity following cervical paravertebral nerve block. Case presentation:A 44-year-old female was admitted to Republican Vilnius University Hospital, with symptoms of sus...

journal_title：Open medicine (Warsaw, Poland)

authors： Vosylius S,Uvarovas V,Svediene S,Satkauskas I

更新日期：2019-12-17 00:00:00

abstract：:In this study, an effective means for detecting cancer region through different types of medical image segmentation are presented and explained. We proposed a new method for cancer segmentation on the basis of fuzzy entropy with a level set (FELs) thresholding. The proposed method was successfully utilized to segment ...

journal_title：Open medicine (Warsaw, Poland)

authors： Maolood IY,Al-Salhi YEA,Lu S

更新日期：2018-09-08 00:00:00

abstract：:To observe a therapeutic effect of macrolide antibiotics in children with Pseudomonas aeruginosa pneumonia. Fifty-four cases of children with Pseudomonas aeruginosa pneumonia were randomly divided into an observation group (n=30) and a control group (n=24). The observation group was treated with macrolide antibiotics ...

journal_title：Open medicine (Warsaw, Poland)

authors： Huang XQ,Deng L,Lu G,He CH,Wu PQ,Xie ZW,Ashraf MA

更新日期：2015-12-17 00:00:00

abstract：:The aim of this study was to evaluate the role of miR-181a-5p in sepsis, and to further explore the molecular mechanism. RAW 264.7 cells were stimulated with 1 μg/ml LPS for 4 hours. Firstly, qRT-PCR and ELISA was adopted to evaluate the expression of miR-181a-5p and p ro-inflammatory cytokines in RAW 264.7 macrophage...

journal_title：Open medicine (Warsaw, Poland)

authors： Huang Z,Xu H

更新日期：2019-11-20 00:00:00