abstract：:The increase in the aged population led to a global rise in the demand for elderly healthcare services, such as long-term care facilities (LTCFs), nursing homes, residential homes. Unfortunately, the spread of multidrug-resistant organisms (MDROs) in these structures represent an urgent public health threat requiring ...

journal_title：Aging clinical and experimental research

authors： Tinelli M,Tiseo G,Falcone M,ESCMID Study Group for Infections in the Elderly.

更新日期：2021-01-11 00:00:00

abstract：BACKGROUND:Art-based activities like painting workshops demonstrated health benefits in older individuals living in home care facilities. Few studies examined the effects of painting workshops in geriatric inpatients. AIM:The study aims to examine whether the participation in painting workshops performed in patients a...

journal_title：Aging clinical and experimental research

authors： Beauchet O,Lafleur L,Remondière S,Galery K,Vilcocq C,Launay CP

更新日期：2020-12-01 00:00:00

abstract：INTRODUCTION:Patient navigation improves outcomes in various clinical contexts, but has not been evaluated in secondary fracture prevention. METHODS:We retrospectively reviewed charts of patients, age 50 + from April to October, 2016 hospitalized with fragility fracture contacted by a patient navigator. Patients were ...

journal_title：Aging clinical and experimental research

authors： Jia KQ,Southerland L,Phieffer L,Stephens JA,Ing SW

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Frailty assessment has acquired an increasing importance in recent years and it has been demonstrated that this vulnerable profile predisposes elderly patients to a worse outcome after surgery. Therefore, it becomes paramount to perform an accurate stratification of surgical risk in elderly undergoing emerge...

journal_title：Aging clinical and experimental research

authors： Costa G,Bersigotti L,Massa G,Lepre L,Fransvea P,Lucarini A,Mercantini P,Balducci G,Sganga G,Crucitti A,ERASO (Elderly Risk Assessment, Surgical Outcome) Collaborative Study Group.

更新日期：2020-11-18 00:00:00

abstract：BACKGROUND:Influence of cognitive intervention programs on brain activity has not been enough explored. AIMS:The aims of the present study were to clarify changes in brain activity from a cognitive intervention program utilizing the board game "Go" and to examine the relationship between brain activity and the acquisi...

journal_title：Aging clinical and experimental research

authors： Iizuka A,Ishii K,Wagatsuma K,Ishibashi K,Onishi A,Tanaka M,Suzuki H,Awata S,Fujiwara Y

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVES:Association between socio-demographic factors and dementia risk is studied in general but not for atrial fibrillation (AF) patients. METHODS:We studied AF patients ≥ 45 years in Sweden 1998-2012 (n = 537,513) using the Total Population Register for socio-demographic factors, the Swedish Cause of Death Regis...

journal_title：Aging clinical and experimental research

authors： Wändell P,Carlsson AC,Li X,Gasevic D,Sundquist J,Sundquist K

更新日期：2020-11-01 00:00:00

abstract：AIMS:This study aimed at examining whether ankle-brachial index (ABI) and brachial-ankle pulse wave velocity (baPWV) were independently associated with carotid Intima-media thickness (CIMT) or carotid artery plaque (CAP) in elderly people. METHODS:A cross-sectional analysis was performed in 155 individuals aged over 7...

journal_title：Aging clinical and experimental research

authors： Pan FF,Xu CC,Hu TJ,Fu GX,Zhong Y

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Accumulation of aggregated α-synuclein from the enteric nervous system is believed to be involved in the pathogenesis of Parkinson's disease (PD). The appendix contains abundant α-synuclein and lacks a blood-tissue barrier, suggesting that appendectomy might reduce α-synuclein aggregation, and therefore the ...

journal_title：Aging clinical and experimental research

authors： Lu HT,Shen QY,Xie D,Zhao QZ,Xu YM

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of nutrition combined physical exercise interventions on age-related cognitive decline by a systematic review and meta-analysis. METHODS:We searched 9 databases, including PubMed, EMbase, The Cochrane Library, Web of Science, Science Direct, China National Knowledge Infrastructure (CNK...

journal_title：Aging clinical and experimental research

authors： Liu T,Li N,Hou Z,Liu L,Gao L,Wang L,Tan J

更新日期：2020-10-14 00:00:00

abstract：BACKGROUND:We define active aging as a striving for activities as per one's goals, capacities and opportunities. AIM:To test the 1-year counselling intervention effects on active aging. METHODS:In this two-arm single-blinded randomized controlled trial, the intervention group received individually tailored counsellin...

journal_title：Aging clinical and experimental research

authors： Rantanen T,Hassandra M,Pynnönen K,Siltanen S,Kokko K,Karavirta L,Kauppinen M,Sipilä S,Saajanaho M,Portegijs E

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Frailty is a public health concern in the ageing population. Little is known about the role of gender in the relationship between frailty and health care utilization in older adults. AIMS:The study aims to examine gender differences in the association between different frailty status and health care utiliza...

journal_title：Aging clinical and experimental research

authors： Zhang J,Xu L,Sun L,Li J,Qin W

更新日期：2020-10-01 00:00:00

abstract：AIM:The main purpose of the present study was to verify the feasibility of wearable inertial sensors (IMUs) in a clinical setting to screen gait and functional mobility in Italian older persons. In particular, we intended to verify the capability of IMUs to discriminate individuals with and without cognitive impairment...

journal_title：Aging clinical and experimental research

authors： Mulas I,Putzu V,Asoni G,Viale D,Mameli I,Pau M

更新日期：2020-09-25 00:00:00

abstract：BACKGROUND:It is unclear whether motor-cognitive dual tasks predict cognitive decline better than either motor or cognitive tasks alone. AIMS:To examine the utility of the novel motor-cognitive dual-task test [Stepping Trail Making Test (S-TMT)], as a predictor of cognitive decline, and compare its predictive performa...

journal_title：Aging clinical and experimental research

authors： Osuka Y,Kim H,Watanabe Y,Taniguchi Y,Kojima N,Seino S,Kawai H,Sakurai R,Inagaki H,Awata S,Shinkai S

更新日期：2020-09-23 00:00:00

abstract：BACKGROUND AND AIMS:Walking is the core physical activity of older persons. The assessment of walking capacity is increasingly important for clinical purposes and clinical research. Differences between assessment tools and protocols for short walks to obtain gait characteristics can be responsible for changes, e.g., in...

journal_title：Aging clinical and experimental research

authors： Krumpoch S,Lindemann U,Rappl A,Becker C,Sieber CC,Freiberger E

更新日期：2020-09-15 00:00:00

abstract：BACKGROUND:The effectiveness of computer-based cognitive training (CCT) remains controversial, especially in older adults with neurodegenerative diseases. AIMS:To evaluate the efficacy of CCT in patients with Parkinson's disease and mild cognitive impairment (PD-MCI). METHODS:In this randomized controlled trial, 53 p...

journal_title：Aging clinical and experimental research

authors： Bernini S,Panzarasa S,Barbieri M,Sinforiani E,Quaglini S,Tassorelli C,Bottiroli S

更新日期：2020-09-08 00:00:00

abstract：BACKGROUND:Despite differences between the studies regarding methods for estimating low muscle mass, the European Working Group on Sarcopenia in Older People (EWGSOP) recommends use of two standard deviations (SDs) below the reference sex-specific means of healthy young adults. AIMS:The aim of this study was to determ...

journal_title：Aging clinical and experimental research

authors： Ates Bulut E,Soysal P,Dokuzlar O,Kocyigit SE,Aydin AE,Yavuz I,Isik AT

更新日期：2020-09-01 00:00:00

abstract：INTRODUCTION:Endogenous brain-derived neurotrophic factor (BDNF) is thought to be protective against the neurodegeneration seen in Parkinson's disease (PD), and is thought to increase during exercise. This has been proposed as a possible mechanism by which exercise improves outcomes for people with PD. We conducted a p...

journal_title：Aging clinical and experimental research

authors： O'Callaghan A,Harvey M,Houghton D,Gray WK,Weston KL,Oates LL,Romano B,Walker RW

更新日期：2020-09-01 00:00:00

abstract：INTRODUCTION:Despite the use of the new generation P2Y12 inhibitors (Ticagrelor and Prasugrel) with aspirin is the recommended therapy in acute NSTE-ACS patients, their current use in clinical practice remains quite low and might be related, among several variables, with increased comorbidity burden. We aimed to assess...

journal_title：Aging clinical and experimental research

authors： Aboal J,Llaó I,García García C,Sans-Roselló J,Sambola A,Andrea R,Tomás C,Bonet G,Ariza-Solé A,Viñas D,Oliveras Vilà T,Montero S,Cantalapiedra J,Pujol-López M,Hernández I,Pérez-Rodriguez M,Loma-Osorio P,Sánchez-Salado JC

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Hip fractures (HF) are a major issue worldwide. We aimed at evaluating the practices in delivering care to patients with HF among several Italian Orthogeriatric centers. METHODS:The study took place from February 2016 to July 2018. Seven performance indicators (pre-surgical cognitive assessment, surgery per...

journal_title：Aging clinical and experimental research

authors： Ferrara MC,Andreano A,Tassistro E,Rapazzini P,Zurlo A,Volpato S,Mussi C,Corsi M,Lunardelli ML,Martini E,Castoldi G,De Filippi F,Pizzonia M,Monacelli F,Barone A,Pilotto A,March A,Ungar A,Capelli R,Galmarini V,Franz

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Advances such as passive monitoring technology (PMT), which provides holistic supervision of chronically ill and elderly patients, enable and support improved monitoring and observation, thus empowering the growing population of older adults to live more independently while lowering health care expenses. AI...

journal_title：Aging clinical and experimental research

authors： Schneider JE,Cooper J,Scheibling C,Parikh A

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:The aging trajectory from a state of robustness and good health proceeds from sarcopenia to frailty followed by disability and death due to decline in skeletal muscle mass and function. Sarcopenia is now formally recognized as a muscle disease with an ICD-10-MC diagnosis code. The autophagic response seems t...

journal_title：Aging clinical and experimental research

authors： Rajan SP,Anwar M,Jain B,Khan MA,Dey S,Dey AB

更新日期：2020-06-27 00:00:00

abstract：BACKGROUND:The role played by cognitive reserve for the maintenance of numeracy skills in late adulthood is still not sufficiently explored. AIMS:This study mainly investigated whether cognitive reserve (i.e., vocabulary) mediates on the relationship between non-verbal reasoning and addition and multiplication skills ...

journal_title：Aging clinical and experimental research

authors： Mulas I,Ruiu M,Fastame MC

更新日期：2020-06-18 00:00:00

abstract：BACKGROUND:Cognitive and physical deficits independently raise the risk for negative events in older adults. Less is known about whether their co-occurrence constitutes a distinct risk profile. This study quantifies the association between cognitive impairment, no dementia (CIND), slow walking speed (WS) and their comb...

journal_title：Aging clinical and experimental research

authors： Grande G,Vetrano DL,Fratiglioni L,Marseglia A,Vanacore N,Laukka EJ,Welmer AK,Rizzuto D

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Malnutrition and poor physical performance are both conditions that increase in prevalence with age; however, their interrelation in a clinically relevant population has not been thoroughly studied. AIMS:This study aimed to determine the strength of the association between malnutrition and measures of both ...

journal_title：Aging clinical and experimental research

authors： Ramsey KA,Meskers CGM,Trappenburg MC,Verlaan S,Reijnierse EM,Whittaker AC,Maier AB

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:It is important to identify the relevant parameters of physical performance to prevent early functional decline and to prolong independent living. The aim of this study is to describe the development of physical performance in a healthy community-dwelling older cohort aged 70+ years using comprehensive asses...

journal_title：Aging clinical and experimental research

authors： Diekmann R,Hellmers S,Elgert L,Fudickar S,Heinks A,Lau S,Bauer JM,Zieschang T,Hein A

更新日期：2020-05-01 00:00:00

abstract：:MPI_AGE is a European Union co-funded research project aimed to use the Multidimensional Prognostic Index (MPI), a validated Comprehensive Geriatric Assessment (CGA)-based prognostic tool, to develop predictive rules that guide clinical and management decisions in older people in different European countries. A series...

journal_title：Aging clinical and experimental research

authors： Cruz-Jentoft AJ,Daragjati J,Fratiglioni L,Maggi S,Mangoni AA,Mattace-Raso F,Paccalin M,Polidori MC,Topinkova E,Ferrucci L,Pilotto A,MPI_AGE Investigators.

更新日期：2020-05-01 00:00:00

abstract：AIM:Falls are a significant problem for older people, but are few studies of the risk of falling in residents of nursing homes in Japan. We aimed to investigate the risk factors for falls and the association of medication use and falls in nursing home residents in Japan. METHODS:This case-control study reviewed the re...

journal_title：Aging clinical and experimental research

authors： Park H,Satoh H,Miki A,Maki H,Asai K,Shiraishi A,Urushihara H,Sawada Y

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Since oral organs function in the first stage of the swallowing process, it is possible that decline in swallowing function can be partly related to oral frailty. AIMS:The purpose of this study was to investigate the association between swallowing function and oral function among community-dwelling elderly ...

journal_title：Aging clinical and experimental research

authors： Takeuchi N,Sawada N,Ekuni D,Morita M

更新日期：2020-04-18 00:00:00

abstract：BACKGROUND:The platelet to lymphocyte ratio (PLR) is a novel biomarker to predict the prognosis of acute myocardial infarction (AMI) patients. AIM:The study aimed to evaluate the in-hospital outcomes of elderly patients with AMI and assessed the prognostic value of PLR on in-hospital adverse events. METHODS:A total o...

journal_title：Aging clinical and experimental research

authors： Li L,Ma Y,Geng XB,Tan Z,Wang JH,Cui C,Wang HL,Shang XM

更新日期：2020-04-16 00:00:00

abstract：:Osteoarthritis (OA) is the most common joint condition and, with a burgeoning ageing population, is due to increase in prevalence. Beyond conventional medical and surgical interventions, there are an increasing number of 'alternative' therapies. These alternative therapies may have a limited evidence base and, for thi...

journal_title：Aging clinical and experimental research

authors： Fuggle NR,Cooper C,Oreffo ROC,Price AJ,Kaux JF,Maheu E,Cutolo M,Honvo G,Conaghan PG,Berenbaum F,Branco J,Brandi ML,Cortet B,Veronese N,Kurth AA,Matijevic R,Roth R,Pelletier JP,Martel-Pelletier J,Vlaskovska M,Thoma

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Interprofessional collaborative practice (ICP) is currently recommended for the delivery of high-quality integrated care for older people. Frailty prevention and management are key elements to be tackled on a multi-professional level. AIM:This study aims to develop a consensus-based European multi-professio...

journal_title：Aging clinical and experimental research

authors： Roller-Wirnsberger R,Lindner S,Liew A,O'Caoimh R,Koula ML,Moody D,Espinosa JM,van Durme T,Dimitrov P,Benjak T,Nicolaidou E,Hammar T,Vanhecke E,Junius-Walker U,Csizmadia P,Galluzzo L,Macijauskienė J,Salem M,Rietman L,

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:The Short Physical Performance Battery (SPPB) and the De Morton Mobility Index (DEMMI) are two commonly used instruments to assess mobility in older patients. AIMS:To compare the two assessments in acute senior trauma patients with regard to sensitivity to change during an acute care, and prediction of disc...

journal_title：Aging clinical and experimental research

authors： Gazzotti A,Meyer U,Freystaetter G,Palzer M,Theiler R,Abderhalden L,Bischoff-Ferrari HA

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Aging has several effects on auditory processing with the most important effect known as speech perception impairment in noise. AIMS:The aim of the present study was to investigate the effects of aging on spatial hearing using quick speech in noise (QSIN) and binaural masking level difference (BMLD) tests a...

journal_title：Aging clinical and experimental research

authors： Adel Ghahraman M,Ashrafi M,Mohammadkhani G,Jalaie S

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND/AIM:Polypharmacy and inappropriate medication use in older adults is a major public health problem associated with morbidity and mortality. Aging is associated with metabolic changes and decreased drug clearance, increased drug-drug interactions, prescribing cascades, and potentially inappropriate medication...

journal_title：Aging clinical and experimental research

authors： Kucukdagli P,Bahat G,Bay I,Kilic C,Oren MM,Turkmen BO,Karan MA

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Adaptation to strength training in very old mobility-limited individuals is not fully characterized. Therefore, the aim of this study was to perform a thorough investigation of the adaptation to a lower body strength training regime in this population, with particular emphasis on the relationship between cha...

journal_title：Aging clinical and experimental research

authors： Aas SN,Seynnes O,Benestad HB,Raastad T

更新日期：2020-04-01 00:00:00

abstract：AIMS:The objective of this study was to examine baseline frailty status (including cognitive deficits) and important clinical outcomes, to inform shared decision-making in older adults receiving transcatheter aortic valve implantation (TAVI). METHODS AND RESULTS:We conducted a prospective, observational study of 82 TA...

journal_title：Aging clinical and experimental research

authors： Skaar E,Øksnes A,Eide LSP,Norekvål TM,Ranhoff AH,Nordrehaug JE,Forman DE,Schoenenberger AW,Hufthammer KO,Kuiper KK,Bleie Ø,Packer EJS,Langørgen J,Haaverstad R,Schaufel MA

更新日期：2020-03-19 00:00:00

abstract：BACKGROUND:There is a high burden of antipsychotic use in residential aged care facilities (RACFs) and there is concern regarding potential inappropriate prescribing of antipsychotics in response to mild behavioural symptoms. Antipsychotic use has been associated with a higher risk of mortality in community-dwelling ol...

journal_title：Aging clinical and experimental research

authors： Harrison SL,Sluggett JK,Lang C,Whitehead C,Crotty M,Corlis M,Wesselingh S,Inacio MC

更新日期：2020-03-11 00:00:00

abstract：INTRODUCTION:Using biomarkers to predict mortality in patients with sepsis is important because these patients frequently have high mortality rates and unsatisfactory outcomes. The performance of N-terminal pro-brain natriuretic peptide (NT-pro-BNP) and C-reactive protein (CRP) to predict clinical outcomes in elderly s...

journal_title：Aging clinical and experimental research

authors： Li H,Shan-Shan Z,Jian-Qiang K,Ling Y,Fang L

更新日期：2020-03-01 00:00:00

abstract：:Alzheimer and Parkinson's diseases are neurodegenerative aging-related pathological conditions, mainly caused by the interplay of genetic and non-genetic factors and whose incidence rate is going to drastically increase given the growing life expectancy. To address these complex multifactorial traits, a systems biolog...

journal_title：Aging clinical and experimental research

authors： Gentile G,La Cognata V,Cavallaro S

更新日期：2020-02-06 00:00:00

abstract：BACKGROUND:In spite of a rapidly ageing population, there is a lack of population-based data on mortality among nursing home residents in Southern Europe. AIMS:To assess mortality rates, their determinants, and causes of death in newly admitted nursing home residents in the Veneto region (northeastern Italy). METHODS...

journal_title：Aging clinical and experimental research

authors： Braggion M,Pellizzari M,Basso C,Girardi P,Zabeo V,Lamattina MR,Corti MC,Fedeli U

更新日期：2020-02-01 00:00:00