听力与言语-语言病理学

行为科学

医学伦理学

你正在浏览Aging and Disease期刊下所有文献
  • Alteration of Metabolic Profile and Potential Biomarkers in the Plasma of Alzheimer's Disease.

    abstract::The expending of elderly population worldwide has resulted in a dramatic rise in the incidence of chronic diseases such as Alzheimer's disease (AD). Inadequate understanding of the mechanisms underlying AD has hampered the development of efficient tools for definitive diagnosis and curative interventions. Previous stu...

    journal_title:Aging and disease

    pub_type: 杂志文章

    doi:10.14336/AD.2020.0217

    authors: Shao Y,Ouyang Y,Li T,Liu X,Xu X,Li S,Xu G,Le W

    更新日期:2020-12-01 00:00:00

  • The Critical Role of SIRT1 in Parkinson's Disease: Mechanism and Therapeutic Considerations.

    abstract::Silence information regulator 1 (SIRT1), a member of the sirtuin family, targets histones and many non-histone proteins and participates in various physiological functions. The enzymatic activity of SIRT1 is decreased in patients with Parkinson's disease (PD), which may reduce their ability to resist neuronal damage c...

    journal_title:Aging and disease

    pub_type: 杂志文章,评审

    doi:10.14336/AD.2020.0216

    authors: Li X,Feng Y,Wang XX,Truong D,Wu YC

    更新日期:2020-12-01 00:00:00

  • Prebiotics Regulation of Intestinal Microbiota Attenuates Cognitive Dysfunction Induced by Surgery Stimulation in APP/PS1 Mice.

    abstract::Emerging evidence indicates that the intestinal microbiota could interact with the central nervous system and modulate multiple pathophysiological changes, including the integrity of intestinal barrier and blood-brain barrier, as well as neuroinflammatory response. In the present study, we investigated the potential r...

    journal_title:Aging and disease

    pub_type: 杂志文章

    doi:10.14336/AD.2020.0106

    authors: Han D,Li Z,Liu T,Yang N,Li Y,He J,Qian M,Kuang Z,Zhang W,Ni C,Guo X

    更新日期:2020-10-01 00:00:00

  • Roles of Biomarkers in Myocardial Fibrosis.

    abstract::Myocardial fibrosis is observed in various cardiovascular diseases and plays a key role in the impairment of cardiac function. Endomyocardial biopsy, as the gold standard for the diagnosis of myocardial fibrosis, has limitations in terms of clinical application. Therefore, biomarkers have been recommended for noninvas...

    journal_title:Aging and disease

    pub_type: 杂志文章,评审

    doi:10.14336/AD.2020.0604

    authors: Ding Y,Wang Y,Zhang W,Jia Q,Wang X,Li Y,Lv S,Zhang J

    更新日期:2020-10-01 00:00:00

  • The Significance of 8-oxoGsn in Aging-Related Diseases.

    abstract::Aging is a common risk factor for the occurrence and development of many diseases, such as Parkinson's disease, Alzheimer's disease, diabetes, hypertension, atherosclerosis and coronary heart disease, and cancer, among others, and is a key problem threatening the health and life expectancy of the elderly. Oxidative da...

    journal_title:Aging and disease

    pub_type: 杂志文章,评审

    doi:10.14336/AD.2019.1021

    authors: Zhang X,Li L

    更新日期:2020-10-01 00:00:00

  • Decreased Naïve T-cell Production Leading to Cytokine Storm as Cause of Increased COVID-19 Severity with Comorbidities.

    abstract::Aging, type 2 diabetes, and male gender are major risk factors leading to increased COVID-19 morbidity and mortality. Thymic production and the export of naïve T cells decrease with aging through the effects of androgens in males and in type 2 diabetes. Furthermore, with aging, recovery of naïve T-cell populations aft...

    journal_title:Aging and disease

    pub_type: 杂志文章

    doi:10.14336/AD.2020.0619

    authors: Schwartz MD,Emerson SG,Punt J,Goff WD

    更新日期:2020-07-23 00:00:00

  • DICER1 in the Pathogenesis of Age-related Macular Degeneration (AMD) - Alu RNA Accumulation versus miRNA Dysregulation.

    abstract::DICER1 deficiency in the retinal pigment epithelium (RPE) was associated with the accumulation of Alu transcripts and implicated in geographic atrophy (GA), a form of age-related macular degeneration (AMD), an eye disease leading to blindness in millions of people. Although the exact mechanism of this association is n...

    journal_title:Aging and disease

    pub_type: 杂志文章,评审

    doi:10.14336/AD.2019.0809

    authors: Kaarniranta K,Pawlowska E,Szczepanska J,Blasiak J

    更新日期:2020-07-23 00:00:00

  • Biogenesis, Features, Functions, and Disease Relationships of a Specific Circular RNA: CDR1as.

    abstract::In 2011, Hansen discovered the natural antisense transcript (NAT) of the cerebellar degeneration-related protein 1 gene (CDR1), and further described CDR1 NAT as a circular RNA (CircRNA). CDR1 antisense RNA (CDR1as), which is the official name of CDR1 NAT, is conserved and extensively expressed in most eutherian mamma...

    journal_title:Aging and disease

    pub_type: 杂志文章,评审

    doi:10.14336/AD.2019.0920

    authors: Guo Z,Cao Q,Zhao Z,Song C

    更新日期:2020-07-23 00:00:00

  • Cellular and Molecular Biomarkers Indicate Premature Aging in Pseudoxanthoma Elasticum Patients.

    abstract::The molecular processes of aging are very heterogenic and not fully understood. Studies on rare progeria syndromes, which display an accelerated progression of physiological aging, can help to get a better understanding. Pseudoxanthoma elasticum (PXE) caused by mutations in the ATP-binding cassette sub-family C member...

    journal_title:Aging and disease

    pub_type: 杂志文章

    doi:10.14336/AD.2019.0610

    authors: Tiemann J,Wagner T,Vanakker OM,van Gils M,Cabrera JB,Ibold B,Faust I,Knabbe C,Hendig D

    更新日期:2020-05-09 00:00:00

  • Dementia Risk in Type 2 Diabetes Patients: Acarbose Use and Its Joint Effects with Metformin and Pioglitazone.

    abstract::This population-based retrospective cohort study investigated dementia risk associated with acarbose in patients with type 2 diabetes mellitus by using Taiwan's National Health Insurance database. A cohort of 15,524 matched pairs of ever and never users of acarbose based on propensity score matching was enrolled from ...

    journal_title:Aging and disease

    pub_type: 杂志文章,评审

    doi:10.14336/AD.2019.0621

    authors: Tseng CH

    更新日期:2020-05-09 00:00:00

  • Disease Progression-Dependent Expression of CD200R1 and CX3CR1 in Mouse Models of Parkinson's Disease.

    abstract::Microglial activation is an important contributor to the pathogenesis of Parkinson's disease (PD). Microglia are tightly and efficiently regulated by immune checkpoints, including CD200-CD200R1 and CX3CL1-CX3CR1. Understanding the involvement of these checkpoints in disease progression provides important insights into...

    journal_title:Aging and disease

    pub_type: 杂志文章

    doi:10.14336/AD.2019.0615

    authors: Wang L,Liu Y,Yan S,Du T,Fu X,Gong X,Zhou X,Zhang T,Wang X

    更新日期:2020-03-09 00:00:00

  • Understanding the Physiological Links Between Physical Frailty and Cognitive Decline.

    abstract::Declines in both physical and cognitive function are associated with increasing age. Understanding the physiological link between physical frailty and cognitive decline may allow us to develop interventions that prevent and treat both conditions. Although there is significant epidemiological evidence linking physical ...

    journal_title:Aging and disease

    pub_type: 杂志文章,评审

    doi:10.14336/AD.2019.0521

    authors: Ma L,Chan P

    更新日期:2020-03-09 00:00:00

  • Predictive Value of Pin1 in Cervical Low-Grade Squamous Intraepithelial Lesions and Inhibition of Pin1 Exerts Potent Anticancer Activity against Human Cervical Cancer.

    abstract::Many oncogenes are involved in the progression from low-grade squamous intraepithelial lesions (LSILs) to high-grade squamous intraepithelial lesions (HSILs); which greatly increases the risk of cervical cancer (CC). Thus, a reliable biomarker for risk classification of LSILs is urgently needed. The prolyl isomerase P...

    journal_title:Aging and disease

    pub_type: 杂志文章

    doi:10.14336/AD.2019.0415

    authors: Guo YT,Lu Y,Jia YY,Qu HN,Qi D,Wang XQ,Song PY,Jin XS,Xu WH,Dong Y,Liang YY,Quan CS

    更新日期:2020-02-01 00:00:00

  • Roles and Functions of Exosomal Non-coding RNAs in Vascular Aging.

    abstract::Aging is a progressive loss of physiological integrity and functionality process which increases susceptibility and mortality to diseases. Vascular aging is a specific type of organic aging. The structure and function changes of endothelial cells (ECs) and vascular smooth muscle cells (VSMCs) are the main cause of vas...

    journal_title:Aging and disease

    pub_type: 杂志文章,评审

    doi:10.14336/AD.2019.0402

    authors: Ni YQ,Lin X,Zhan JK,Liu YS

    更新日期:2020-02-01 00:00:00

  • Novel Role of Lck in Leptin-Induced Inflammation and Implications for Renal Aging.

    abstract::Aging is associated with increased fat mass and elevated serum leptin levels (hyperleptinemia), causing proinflammation in the kidneys where it plays a primary role in the removal of endogenous leptin from the circulation. Lymphocyte-specific kinase (Lck) is a positive regulator of inflammatory signaling and a potenti...

    journal_title:Aging and disease

    pub_type: 杂志文章

    doi:10.14336/AD.2019.0218

    authors: Kim DH,Park JW,Jeong HO,Lee B,Chung KW,Lee Y,Jung HJ,Hyun MK,Lee AK,Kim BM,Yu BP,Chung HY

    更新日期:2019-12-01 00:00:00

  • The Potential Markers of Circulating microRNAs and long non-coding RNAs in Alzheimer's Disease.

    abstract::Alzheimer's disease (AD) is a neurodegenerative disorder and one of the leading causes of disability and mortality in the late life with no curative treatment currently. Thus, it is urgently to establish sensitive and non-invasive biomarkers for AD diagnosis, particularly in the early stage. Recently, emerging number ...

    journal_title:Aging and disease

    pub_type: 杂志文章,评审

    doi:10.14336/AD.2018.1105

    authors: Zhao Y,Zhang Y,Zhang L,Dong Y,Ji H,Shen L

    更新日期:2019-12-01 00:00:00

  • Characterization of Alzheimer's Disease Using Ultra-high b-values Apparent Diffusion Coefficient and Diffusion Kurtosis Imaging.

    abstract::The aim of the study is to investigate the diffusion characteristics of Alzheimer's disease (AD) patients using an ultra-high b-values apparent diffusion coefficient (ADC_uh) and diffusion kurtosis imaging (DKI). A total of 31 AD patients and 20 healthy controls (HC) who underwent both MRI examination and clinical ass...

    journal_title:Aging and disease

    pub_type: 杂志文章

    doi:10.14336/AD.2018.1129

    authors: Xue Y,Zhang Z,Wen C,Liu H,Wang S,Li J,Zhuge Q,Chen W,Ye Q

    更新日期:2019-10-01 00:00:00

  • Galectin-3 Mediates Endothelial-to-Mesenchymal Transition in Pulmonary Arterial Hypertension.

    abstract::Galectin-3 (Gal-3) is highly expressed in fibrotic tissue related to diverse etiologies. endothelial-to-mesenchymal transition (EndoMT), A less well studied phenomenon serves as a critical process in pulmonary vascular remodeling associated with the development of pulmonary arterial hypertension (PAH). EndoMT is hypot...

    journal_title:Aging and disease

    pub_type: 杂志文章

    doi:10.14336/AD.2018.1001

    authors: Li T,Zha L,Luo H,Li S,Zhao L,He J,Li X,Qi Q,Liu Y,Yu Z

    更新日期:2019-08-01 00:00:00

  • Metabolomics Coupled with Transcriptomics Approach Deciphering Age Relevance in Sepsis.

    abstract::Sepsis is a severe disease frequently occurred in the Intenisive Care Unit (ICU), which has a very high morbidity and mortality, especially in patients aged over 65 years. Owing to the aging effect and the ensuing deterioration of body function, the elder patients may have atypical responses to sepsis. Diagnosis and p...

    journal_title:Aging and disease

    pub_type: 杂志文章

    doi:10.14336/AD.2018.1027

    authors: Xu D,Liao S,Li P,Zhang Q,Lv Y,Fu X,Yang M,Wang J,Kong L

    更新日期:2019-08-01 00:00:00

  • Duration and Quality of Sleep and Risk of Physical Function Impairment and Disability in Older Adults: Results from the ENRICA and ELSA Cohorts.

    abstract::Sleep duration and quality have been associated with poor physical function, but both the temporality of the association and the independence of sleep duration and quality are unclear. We examined the prospective association of sleep duration and quality with physical function impairment and disability in older adults...

    journal_title:Aging and disease

    pub_type: 杂志文章

    doi:10.14336/AD.2018.0611

    authors: Campanini MZ,Mesas AE,Carnicero-Carreño JA,Rodríguez-Artalejo F,Lopez-Garcia E

    更新日期:2019-06-01 00:00:00

  • A Microcirculatory Theory of Aging.

    abstract::Aging is the progressive decline of physiological functions necessary for survival and reproduction. In gaining a better understanding of the inevitable aging process, the hope is to preserve, promote, or delay healthy aging through the treatment of common age-associated diseases. Although there are theories that try ...

    journal_title:Aging and disease

    pub_type: 杂志文章

    doi:10.14336/AD.2019.0315

    authors: Jin K

    更新日期:2019-06-01 00:00:00

  • Deficiency of Yes-Associated Protein Induces Cataract in Mice.

    abstract::Cataract is a major cause of blindness worldwide, its complicated and unclear etiopathogenesis limit effective therapy. Here, we found that Yap, a downstream effector of the Hippo pathway, is specifically expressed in lens epithelial cells and Yap conditional knockout (cKO) in the lens leads to cataract. Histologicall...

    journal_title:Aging and disease

    pub_type: 杂志文章

    doi:10.14336/AD.2018.0910

    authors: He Q,Gao Y,Wang T,Zhou L,Zhou W,Yuan Z

    更新日期:2019-04-01 00:00:00

  • DRAM is Involved in Hypoxia/Ischemia-Induced Autophagic Apoptosis in Hepatocytes.

    abstract::Liver hypoxia/ischemia injury leads to acute liver injury, delayed graft dysfunction, and failure during liver transplantation. Previous studies showed that autophagy is involved in liver hypoxia/ischemia injury. Our and others' studies have found that the damage-regulated autophagy modulator (DRAM) could induce the a...

    journal_title:Aging and disease

    pub_type: 杂志文章

    doi:10.14336/AD.2018.0210

    authors: Xu J,Zang Y,Liu D,Yang T,Wang J,Wang Y,Liu X,Chen D

    更新日期:2019-02-01 00:00:00

  • Prognostic Nomogram Associated with Longer Survival in Amyotrophic Lateral Sclerosis Patients.

    abstract::Better understanding of survival factors in amyotrophic lateral sclerosis (ALS) could help physicians and patients schedule therapeutic interventions. We conducted a study to evaluate the predictive factors associated with longer survival and construct prognostic nomogram in ALS patients. A total of 553 ALS patients w...

    journal_title:Aging and disease

    pub_type: 杂志文章

    doi:10.14336/AD.2017.1016

    authors: Wei QQ,Chen Y,Chen X,Cao B,Ou R,Zhang L,Hou Y,Shang H

    更新日期:2018-12-04 00:00:00

  • Olfactory Dysfunction and Its Relationship with Clinical Symptoms of Alzheimer Disease.

    abstract::Our study aimed to analyse the olfactory dysfunction (OD) evaluations between self-report, the Hyposmia Rating Scale (HRS) and the Sniffin' Sticks test, and the relationship between OD and clinical features of AD. Sixty patients with AD dementia, 37 patients with mild cognitive impairment (MCI) due to AD and 30 health...

    journal_title:Aging and disease

    pub_type: 杂志文章

    doi:10.14336/AD.2018.0819

    authors: Yu Q,Guo P,Li D,Zuo L,Lian T,Yu S,Hu Y,Liu L,Jin Z,Wang R,Piao Y,Li L,Wang X,Zhang W

    更新日期:2018-12-04 00:00:00

  • Searching for Factors Raising the Incidence of Metabolic Syndrome Among 45-60-Year-Old Women.

    abstract::Metabolic syndrome is an increasing health problem, whose pathogenesis may be associated with genetic factors. The main purpose of our study was to assess relationships between MetS and the presence of the FTO rs9939609, the MC4R rs17782313, and the PPAR-γ rs1801282 polymorphisms in 45-60-year-old women. The study inc...

    journal_title:Aging and disease

    pub_type: 杂志文章

    doi:10.14336/AD.2017.1027

    authors: Małgorzata S,Jacek B,Jerzy OA,Piotr C,Anna J,Elżbieta G

    更新日期:2018-10-01 00:00:00

  • Neuroprotective Effect of Caffeic Acid Phenethyl Ester in A Mouse Model of Alzheimer's Disease Involves Nrf2/HO-1 Pathway.

    abstract::Alzheimer's disease (AD) is a progressive pathology, where dementia symptoms gradually worsen over a number of years. The hallmarks of AD, such as amyloid β-peptide (Aβ) in senile plaque and neurofibrillary tangles, are strongly intertwined with oxidative stress, which is considered one of the common effectors of the ...

    journal_title:Aging and disease

    pub_type: 杂志文章

    doi:10.14336/AD.2017.0903

    authors: Morroni F,Sita G,Graziosi A,Turrini E,Fimognari C,Tarozzi A,Hrelia P

    更新日期:2018-08-01 00:00:00

  • Mitochondrial Pharmacology of Dimebon (Latrepirdine) Calls for a New Look at its Possible Therapeutic Potential in Alzheimer's Disease.

    abstract::Dimebon (latrepirdine), an old antihistaminic drug, showed divergent results in two large clinical trials in Alzheimer disease (AD), which according to our review might be related to the specific pharmacological properties of the drug and the different patient populations included in both studies. Out of the many phar...

    journal_title:Aging and disease

    pub_type: 杂志文章,评审

    doi:10.14336/AD.2017.1014

    authors: Eckert SH,Gaca J,Kolesova N,Friedland K,Eckert GP,Muller WE

    更新日期:2018-08-01 00:00:00

  • Prehospital Notification Procedure Improves Stroke Outcome by Shortening Onset to Needle Time in Chinese Urban Area.

    abstract::Intravenous thrombolysis (IVT) with recombinant tissue plasminogen activator (rt-PA) can improve clinical outcome in eligible patients with acute ischemic stroke (AIS). However, its efficacy is strongly time-dependent. This study was aimed to examine whether prehospital notification by emergency medical service (EMS) ...

    journal_title:Aging and disease

    pub_type: 杂志文章

    doi:10.14336/AD.2017.0601

    authors: Zhang S,Zhang J,Zhang M,Zhong G,Chen Z,Lin L,Lou M

    更新日期:2018-06-01 00:00:00

  • Mammalian Sterile20-like Kinases: Signalings and Roles in Central Nervous System.

    abstract::Mammalian Sterile20-like (MST) kinases are located upstream in the mitogen-activated protein kinase pathway, and play an important role in cell proliferation, differentiation, renewal, polarization and migration. Generally, five MST kinases exist in mammalian signal transduction pathways, including MST1, MST2, MST3, M...

    journal_title:Aging and disease

    pub_type: 杂志文章,评审

    doi:10.14336/AD.2017.0702

    authors: Chen S,Fang Y,Xu S,Reis C,Zhang J

    更新日期:2018-06-01 00:00:00

  • Diagnostic and Immunosuppressive Potential of Elevated Mir-424 Levels in Circulating Immune Cells of Ischemic Stroke Patients.

    abstract::Our previous study demonstrated that microRNA-424 (miR-424) protected against experimental stroke through inhibition of microglial proliferation and activation by targeting cell cycle proteins. The purpose of this study was to further explore the clinical significance of miR-424 in peripheral immune cells of patients ...

    journal_title:Aging and disease

    pub_type: 杂志文章

    doi:10.14336/AD.2017.0602

    authors: Li G,Ma Q,Wang R,Fan Z,Tao Z,Liu P,Zhao H,Luo Y

    更新日期:2018-04-01 00:00:00

  • The Prevalence of Frailty and its Associated Factors in Japanese Hemodialysis Patients.

    abstract::The population undergoing dialysis is aging worldwide, particularly in Japan. The clinical condition of frailty is the most problematic expression in the elderly population. Potential pathophysiological factors of frailty present in patients with CKD and are accentuated in patients with ESRD. The aim of this study was...

    journal_title:Aging and disease

    pub_type: 杂志文章

    doi:10.14336/AD.2017.0429

    authors: Takeuchi H,Uchida HA,Kakio Y,Okuyama Y,Okuyama M,Umebayashi R,Wada K,Sugiyama H,Sugimoto K,Rakugi H,Wada J

    更新日期:2018-04-01 00:00:00

  • Serum Zonulin and Endotoxin Levels in Exceptional Longevity versus Precocious Myocardial Infarction.

    abstract::Endotoxemia-induced inflammation has been associated with insulin resistance and atherosclerosis, ultimately increasing the risk of coronary heart disease. Increased intestinal permeability is an important event leading to endotoxemia. This study aims to elucidate the possible association between endotoxin (lipopolysa...

    journal_title:Aging and disease

    pub_type: 杂志文章

    doi:10.14336/AD.2017.0630

    authors: Carrera-Bastos P,Picazo Ó,Fontes-Villalba M,Pareja-Galeano H,Lindeberg S,Martínez-Selles M,Lucia A,Emanuele E

    更新日期:2018-04-01 00:00:00

  • Identification of MAVS as a Novel Risk Factor for the Development of Osteoarthritis.

    abstract::Evidence indicated that inflammatory response and some pattern-recognition receptors play important roles in the occurrence and progression of osteoarthritis. This study is conducted to evaluate the role of RIG-I and its adaptor protein MAVS in the pathogenesis of osteoarthritis. Four SNPs in RIG-I gene and four in MA...

    journal_title:Aging and disease

    pub_type: 杂志文章

    doi:10.14336/AD.2017.0308

    authors: Liu J,Tang LY,Wang YG,Lu SY,Zhang EN,Wang ZG,Zhang HX

    更新日期:2018-02-01 00:00:00

  • Acute Sarcopenia Secondary to Hospitalisation - An Emerging Condition Affecting Older Adults.

    abstract::There has been increasing interest and research into sarcopenia in community-dwelling older adults since the European Working Group on Sarcopenia in Older People (EWGSOP) agreed a consensus definition in 2010. Sarcopenia has been defined as loss of muscle mass with loss of muscle function (strength or physical perform...

    journal_title:Aging and disease

    pub_type: 杂志文章,评审

    doi:10.14336/AD.2017.0315

    authors: Welch C,K Hassan-Smith Z,A Greig C,M Lord J,A Jackson T

    更新日期:2018-02-01 00:00:00

  • The Effects of Baicalin and Baicalein on Cerebral Ischemia: A Review.

    abstract::Ischemic stroke, producing a high mortality and morbidity rate, is a common clinical disease. Enhancing the prevention and control of ischemic stroke is particularly important. Baicalin and its aglycon baicalein are flavonoids extracted from Scutellaria baicalensis, an important traditional Chinese herb. In recent yea...

    journal_title:Aging and disease

    pub_type: 杂志文章,评审

    doi:10.14336/AD.2017.0829

    authors: Liang W,Huang X,Chen W

    更新日期:2017-12-01 00:00:00

  • Parity History Determines a Systemic Inflammatory Response to Spread of Ovarian Cancer in Naturally Aged Mice.

    abstract::Aging intersects with reproductive senescence in women by promoting a systemic low-grade chronic inflammation that predisposes women to several diseases including ovarian cancer (OC). OC risk at menopause is significantly modified by parity records during prior fertile life. To date, the combined effects of age and pa...

    journal_title:Aging and disease

    pub_type: 杂志文章

    doi:10.14336/AD.2017.0110

    authors: Urzua U,Chacon C,Lizama L,Sarmiento S,Villalobos P,Kroxato B,Marcelain K,Gonzalez MJ

    更新日期:2017-10-01 00:00:00

  • Mitochondrial Ferritin Protects Hydrogen Peroxide-Induced Neuronal Cell Damage.

    abstract::Oxidative stress and iron accumulation are tightly associated with neurodegenerative diseases. Mitochondrial ferritin (FtMt) is identified as an iron-storage protein located in the mitochondria, and its role in regulation of iron hemeostasis in neurodegenerative diseases has been reported. However, the role of FtMt in...

    journal_title:Aging and disease

    pub_type: 杂志文章

    doi:10.14336/AD.2016.1108

    authors: Gao G,Zhang N,Wang YQ,Wu Q,Yu P,Shi ZH,Duan XL,Zhao BL,Wu WS,Chang YZ

    更新日期:2017-07-21 00:00:00

  • Geroprotectors: A Unified Concept and Screening Approaches.

    abstract::Although the geroprotectors discovery is a new biomedicine trend and more than 200 compounds can slow aging and increase the lifespan of the model organism, there are still no geroprotectors on the market. The reasons may be partly related to the lack of a unified concept of geroprotector, accepted by the scientific c...

    journal_title:Aging and disease

    pub_type: 杂志文章,评审

    doi:10.14336/AD.2016.1022

    authors: Moskalev A,Chernyagina E,Kudryavtseva A,Shaposhnikov M

    更新日期:2017-05-02 00:00:00

  • Association between Coagulation Function and Cerebral Microbleeds in Ischemic Stroke Patients with Atrial Fibrillation and/or Rheumatic Heart Disease.

    abstract::Cerebral microbleeds (CMBs), which indicate hemorrhage-prone disease, may associate with hemostatic abnormalities, but the association between CMBs and coagulation function is uncertain. We aimed to examine this possible association. The following coagulation function indicators were evaluated in 85 consecutive ischem...

    journal_title:Aging and disease

    pub_type: 杂志文章

    doi:10.14336/AD.2016.0715

    authors: Liu J,Wang D,Xiong Y,Liu B,Lin J,Zhang S,Wu B,Wei C,Liu M

    更新日期:2017-04-01 00:00:00

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