听力与言语-语言病理学

行为科学

医学伦理学

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  • Effects of Different High-Intensity Interval Training Regimens on Endurance and Neuroplasticity After Cerebral Ischemia.

    abstract:BACKGROUND AND PURPOSE:The objective is to compare the effects of high-intensity interval training (HIIT) with long versus short intervals on endurance and motor performance. Their influence on neuroplasticity markers is assessed in the ipsilesional and contralesional cortex and hippocampus since their remodeling could...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.031873

    authors: Pin-Barre C,Hugues N,Constans A,Berton E,Pellegrino C,Laurin J

    更新日期:2021-02-01 00:00:00

  • Dabigatran or Aspirin After Embolic Stroke of Undetermined Source in Patients With Patent Foramen Ovale: Results From RE-SPECT ESUS.

    abstract:BACKGROUND AND PURPOSE:Patent foramen ovale (PFO) may increase the risk of embolic stroke of undetermined source (ESUS). Guidelines suggest anticoagulation may be more effective than antiplatelets in preventing stroke in patients with ESUS and PFO when interventional closure is not performed. METHODS:Patients with ESU...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.031237

    authors: Diener HC,Chutinet A,Easton JD,Granger CB,Kleine E,Marquardt L,Meyerhoff J,Zini A,Sacco RL

    更新日期:2021-01-28 00:00:00

  • Newly Diagnosed Leptospirosis and Subsequent Hemorrhagic Stroke: A Nationwide Population-Based Cohort Study.

    abstract:BACKGROUND AND PURPOSE:Preceding infection as an important risk factor for ischemic stroke has been reported but neglected for hemorrhagic stroke, especially in young and middle-aged patients. This study investigates whether newly diagnosed leptospirosis is associated with an increased risk of stroke. METHODS:We ident...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.029998

    authors: Li KY,Chou MC,Wei JC,Lin MC,Hung YM,Chang R

    更新日期:2021-01-26 00:00:00

  • Invasive Monitoring of Intracranial Pressure After Decompressive Craniectomy in Malignant Stroke.

    abstract:BACKGROUND AND PURPOSE:The role of decompressive hemicraniectomy (DC) in malignant cerebral infarction (MCI) has clearly been established, but little is known about the course of intracranial pressure (ICP) in patients undergoing this surgical measure. In this study, we investigated the role of invasive ICP monitoring ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.032390

    authors: Hernández-Durán S,Meinen L,Rohde V,von der Brelie C

    更新日期:2021-01-01 00:00:00

  • Role of Computed Tomography Perfusion in Identification of Acute Lacunar Stroke Syndromes.

    abstract:BACKGROUND AND PURPOSE:Lacunar syndromes correlate with a lacunar stroke on imaging in 50% to 60% of cases. Computed tomography perfusion (CTP) is becoming the preferred imaging modality for acute stroke triage. We aimed to estimate the sensitivity, specificity, and predictive values for noncontrast computed tomography...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.030455

    authors: Garcia-Esperon C,Visser M,Churilov L,Miteff F,Bivard A,Lillicrap T,Levi CR,Spratt NJ,Parsons MW

    更新日期:2021-01-01 00:00:00

  • Early NT-ProBNP (N-Terminal Probrain Natriuretic Peptide) Elevation Predicts Malignant Edema and Death After Reperfusion Therapy in Acute Ischemic Stroke Patients.

    abstract:BACKGROUND AND PURPOSE:We aimed to investigate the relationship between early NT-proBNP (N-terminal probrain natriuretic peptide) and all-cause death in patients receiving reperfusion therapy, including intravenous thrombolysis and endovascular thrombectomy (EVT). METHODS:This study included 1039 acute ischemic stroke...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.029593

    authors: Zhang X,Yan S,Zhong W,Yu Y,Lou M

    更新日期:2021-01-01 00:00:00

  • Early Infarct Growth Rate Correlation With Endovascular Thrombectomy Clinical Outcomes: Analysis From the SELECT Study.

    abstract:BACKGROUND AND PURPOSE:Time elapsed from last-known well (LKW) and baseline imaging results are influential on endovascular thrombectomy (EVT) outcomes. METHODS:In a prospective multicenter cohort study of imaging selection for endovascular thrombectomy (SELECT [Optimizing Patient's Selection for Endovascular Treatmen...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.030912

    authors: Sarraj A,Hassan AE,Grotta J,Blackburn S,Day A,Abraham M,Sitton C,Dannenbaum M,Cai C,Pujara D,Hicks W,Vora N,Budzik R,Shaker F,Arora A,Riascos RF,Kamal H,Martin-Schild S,Lansberg M,Gupta R,Albers GW,SELECT Invest

    更新日期:2021-01-01 00:00:00

  • Impact of Preexisting Cognitive Impairment and Race/Ethnicity on Functional Outcomes Following Intracerebral Hemorrhage.

    abstract:BACKGROUND AND PURPOSE:In intracerebral hemorrhage (ICH), preexisting cognitive impairment has been identified as a risk factor for increased mortality and morbidity. However, previous studies examined predominantly White populations; therefore, the prevalence and effect of preICH cognitive impairment has not been stud...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.030084

    authors: Sawyer RP,Yim E,Coleman E,Demel SL,Sekar P,Woo D

    更新日期:2021-01-01 00:00:00

  • Microglial Calcium Waves During the Hyperacute Phase of Ischemic Stroke.

    abstract:BACKGROUND AND PURPOSE:Ischemic injury triggers multiple pathological responses in the brain tissue, including spreading depolarizations across the cerebral cortex (cortical spreading depolarizations [CSD]). Microglia have been recently shown to play a significant role in the propagation of CSD. However, the intracellu...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.032766

    authors: Liu L,Kearns KN,Eli I,Sharifi KA,Soldozy S,Carlson EW,Scott KW,Sluzewski MF,Acton ST,Stauderman KA,Kalani MYS,Park M,Tvrdik P

    更新日期:2021-01-01 00:00:00

  • Mismatch Profile Influences Outcome After Mechanical Thrombectomy.

    abstract:BACKGROUND AND PURPOSE:Mechanical thrombectomy (MT) is the recommended treatment for acute ischemic stroke caused by anterior circulation large vessel occlusion. However, despite a high rate of reperfusion, the clinical response to successful MT remains highly variable in the early time window where optimal imaging sel...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.031929

    authors: Olivot JM,Albucher JF,Guenego A,Thalamas C,Mlynash M,Rousseau V,Drif A,Christensen S,Sommet A,Viguier A,Darcourt J,Calvière L,Menegon P,Raposo N,Januel AC,Bonneville F,Tourdias T,Mazighi M,Sibon I,Albers GW,Cognar

    更新日期:2021-01-01 00:00:00

  • Leptomeningeal Collateral Flow Modifies Endovascular Treatment Efficacy on Large-Vessel Occlusion Strokes.

    abstract:BACKGROUND AND PURPOSE:We aim to evaluate if good collateral flow (CF) modifies endovascular therapy (EVT) efficacy on large-vessel stroke. To do that, we used final degree of reperfusion and number of device-passes performed, factors previously associated with better functional outcome, as main outcome measures. METH...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.031338

    authors: García-Tornel Á,Ciolli L,Rubiera M,Requena M,Muchada M,Pagola J,Rodriguez-Luna D,Deck M,Juega J,Rodríguez-Villatoro N,Boned S,Olivé-Gadea M,Sanjuan E,Tomasello A,Piñana C,Hernández D,Álvarez-Sabin J,Molina CA,Ribó M

    更新日期:2021-01-01 00:00:00

  • Association Between Thrombus Perviousness Assessed on Computed Tomography and Stroke Cause.

    abstract:BACKGROUND AND PURPOSE:A recent study proposed that thrombus perviousness (TP)-the degree to which contrast agents penetrate the thrombus in an occluded vessel measured on noncontrast computed tomography (NCCT) and CT angiography-may be associated with cardioembolic stroke cause with high specificity. Our aim was to in...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.031148

    authors: Kufner A,Erdur H,Endres M,Nolte CH,Scheel M,Schlemm L

    更新日期:2020-12-01 00:00:00

  • Strictly Lobar Microbleeds Reflect Amyloid Angiopathy Regardless of Cerebral and Cerebellar Compartments.

    abstract:BACKGROUND AND PURPOSE:We aimed to determine whether lobar cerebellar microbleeds or concomitant lobar cerebellar and deep microbleeds, in the presence of lobar cerebral microbleeds, attribute to underlying advanced cerebral amyloid angiopathy pathology or hypertensive arteriopathy. METHODS:We categorized 71 patients ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.119.028487

    authors: Jung YH,Jang H,Park SB,Choe YS,Park Y,Kang SH,Lee JM,Kim JS,Kim J,Kim JP,Kim HJ,Na DL,Seo SW

    更新日期:2020-12-01 00:00:00

  • Fibrin and Platelet-Rich Composition in Retrieved Thrombi Hallmarks Stroke With Active Cancer.

    abstract:BACKGROUND AND PURPOSE:We aim to investigate whether histopathologic examination of thrombi retrieved from acute ischemic stroke patients undergoing endovascular treatment could distinguish cancer-related stroke from other etiologies. METHODS:Thrombi from patients undergoing endovascular treatment were analyzed. The e...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.032069

    authors: Fu CH,Chen CH,Lin YH,Lee CW,Tsai LK,Tang SC,Shun CT,Jeng JS

    更新日期:2020-12-01 00:00:00

  • Predictors of Unexplained Early Neurological Deterioration After Endovascular Treatment for Acute Ischemic Stroke.

    abstract:BACKGROUND AND PURPOSE:Although the efficacy of endovascular treatment (EVT) in patients with anterior circulation ischemic stroke (AIS) is well documented, early neurological deterioration after EVT remains a serious issue associated with poor outcome. Besides obvious causes, such as lack of reperfusion, procedural co...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.029494

    authors: Girot JB,Richard S,Gariel F,Sibon I,Labreuche J,Kyheng M,Gory B,Dargazanli C,Maier B,Consoli A,Daumas-Duport B,Lapergue B,Bourcier R,ETIS Investigators*.

    更新日期:2020-10-01 00:00:00

  • Effect of Pre- and In-Hospital Delay on Reperfusion in Acute Ischemic Stroke Mechanical Thrombectomy.

    abstract:BACKGROUND AND PURPOSE:Post hoc analyses of randomized controlled clinical trials evaluating mechanical thrombectomy have suggested that admission-to-groin-puncture (ATG) delays are associated with reduced reperfusion rates. Purpose of this analysis was to validate this association in a real-world cohort and to find as...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.030208

    authors: Kaesmacher J,Maamari B,Meinel TR,Piechowiak EI,Mosimann PJ,Mordasini P,Goeldlin M,Arnold M,Dobrocky T,Boeckh-Behrens T,Berndt M,Michel P,Requena M,Benali A,Pierot L,Mendes Pereira V,Boulouis G,Brehm A,Sporns PB,Ospe

    更新日期:2020-10-01 00:00:00

  • Morbidity After Symptomatic Hemorrhage of Cerebral Cavernous Malformation: A Nomogram Approach to Risk Assessment.

    abstract:BACKGROUND AND PURPOSE:Symptomatic hemorrhage contributes to an increased risk of repeated bleeding and morbidity in cerebral cavernous malformation (CCM). A better understanding of morbidity after CCM hemorrhage would be helpful to identify patients of higher risk for unfavorable outcome and tailor individualized mana...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.029942

    authors: Ma L,Zhang S,Li Z,Wu CX,Wang Z,Zhan L,Hao Q,Wang H,Ye X,Chen X,Liu YO,Wang S,Zhao YL

    更新日期:2020-10-01 00:00:00

  • Brain Arteriovenous Malformation Recurrence After Apparent Microsurgical Cure: Increased Risk in Children Who Present With Arteriovenous Malformation Rupture.

    abstract:BACKGROUND AND PURPOSE:Do children have an increased risk for brain arteriovenous malformation (AVM) recurrence compared with adults and does this risk vary depending on initial presentation with AVM rupture? METHODS:We retrospectively studied 115 patients initially presenting with brain AVM under age 25 years who und...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.030135

    authors: Copelan A,Drocton G,Caton MT,Smith ER,Cooke DL,Nelson J,Abla AA,Fox C,Amans MR,Dowd CF,Halbach VV,Higashida RT,Lawton MT,Kim H,Fullerton HJ,Gupta N,Hetts SW,UCSF Center For Cerebrovascular Research and UCSF Pediatric Br

    更新日期:2020-10-01 00:00:00

  • Effect of COVID-19 on Emergent Stroke Care: A Regional Experience.

    abstract:BACKGROUND AND PURPOSE:Anecdotal evidence suggests that the coronavirus disease 2019 (COVID-19) pandemic mitigation efforts may inadvertently discourage patients from seeking treatment for stroke with resultant increased morbidity and mortality. Analysis of regional data, while hospital capacities for acute stroke care...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.030499

    authors: Hsiao J,Sayles E,Antzoulatos E,Stanton RJ,Sucharew H,Broderick JP,Demel SL,Flaherty ML,Grossman AW,Kircher C,Kreitzer N,Peariso K,Prestigiacomo CJ,Shirani P,Walsh KB,Lampton H,Adeoye O,Khatri P

    更新日期:2020-09-01 00:00:00

  • DNA Content in Ischemic Stroke Thrombi Can Help Identify Cardioembolic Strokes Among Strokes of Undetermined Cause.

    abstract:BACKGROUND AND PURPOSE:Identification of acute ischemic stroke (AIS) cause is crucial for guidance of secondary prevention. Previous studies have yielded inconsistent results regarding possible correlations between AIS cause and thrombus composition, as assessed by semiquantitative histological analysis. Here, we perfo...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.029134

    authors: Di Meglio L,Desilles JP,Solonomenjanahary M,Labreuche J,Ollivier V,Dupont S,Deschildre C,Maacha MB,Consoli A,Lapergue B,Piotin M,Blanc R,Ho-Tin-Noe B,Mazighi M,compoCLOT study group†.

    更新日期:2020-09-01 00:00:00

  • Dynamic Regional Brain Atrophy Rates in the First Year After Ischemic Stroke.

    abstract:BACKGROUND AND PURPOSE:Brain atrophy can be regarded as an end-organ effect of cumulative cardiovascular risk factors. Accelerated brain atrophy is described following ischemic stroke, but it is not known whether atrophy rates vary over the poststroke period. Examining rates of brain atrophy allows the identification o...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.030256

    authors: Brodtmann A,Khlif MS,Egorova N,Veldsman M,Bird LJ,Werden E

    更新日期:2020-09-01 00:00:00

  • Neuropathologic and Cognitive Correlates of Enlarged Perivascular Spaces in a Community-Based Cohort of Older Adults.

    abstract:BACKGROUND AND PURPOSE:Enlarged perivascular spaces (EPVS) have been associated with aging, increased stroke risk, decreased cognitive function, and vascular dementia. However, the relationship of EPVS with age-related neuropathologies is not well understood. Therefore, the purpose of this study was to assess the neuro...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.029388

    authors: Javierre-Petit C,Schneider JA,Kapasi A,Makkinejad N,Tamhane AA,Leurgans SE,Mehta RI,Barnes LL,Bennett DA,Arfanakis K

    更新日期:2020-09-01 00:00:00

  • Impact of Goal-Directed Therapy on Delayed Ischemia After Aneurysmal Subarachnoid Hemorrhage: Randomized Controlled Trial.

    abstract:BACKGROUND AND PURPOSE:Delayed cerebral ischemia (DCI) is the most important cause for a poor clinical outcome after a subarachnoid hemorrhage. The aim of this study was to assess whether goal-directed hemodynamic therapy (GDHT), as compared to standard clinical care, reduces the rate of DCI after subarachnoid hemorrha...

    journal_title:Stroke

    pub_type: 杂志文章,随机对照试验

    doi:10.1161/STROKEAHA.120.029279

    authors: Anetsberger A,Gempt J,Blobner M,Ringel F,Bogdanski R,Heim M,Schneider G,Meyer B,Schmid S,Ryang YM,Wostrack M,Schneider J,Martin J,Ehrhardt M,Jungwirth B

    更新日期:2020-08-01 00:00:00

  • Telemedicine Cognitive Behavioral Therapy for Anxiety After Stroke: Proof-of-Concept Randomized Controlled Trial.

    abstract:BACKGROUND AND PURPOSE:Disabling anxiety affects a quarter of stroke survivors but access to treatment is poor. We developed a telemedicine model for delivering guided self-help cognitive behavioral therapy (CBT) for anxiety after stroke (TASK-CBT). We aimed to evaluate the feasibility of TASK-CBT in a randomized contr...

    journal_title:Stroke

    pub_type: 杂志文章,随机对照试验

    doi:10.1161/STROKEAHA.120.029042

    authors: Chun HY,Carson AJ,Tsanas A,Dennis MS,Mead GE,Calabria C,Whiteley WN

    更新日期:2020-08-01 00:00:00

  • Trends in Stroke Recurrence in Mexican Americans and Non-Hispanic Whites.

    abstract:BACKGROUND AND PURPOSE:Stroke incidence and mortality are declining rapidly in developed countries. Little data on ethnic-specific stroke recurrence trends exist. Fourteen-year stroke recurrence trend estimates were evaluated in Mexican Americans and non-Hispanic whites in a population-based study. METHODS:Recurrent s...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.029376

    authors: Sozener CB,Lisabeth LD,Shafie-Khorassani F,Kim S,Zahuranec DB,Brown DL,Skolarus LE,Burke JF,Kerber KA,Meurer WJ,Case E,Morgenstern LB

    更新日期:2020-08-01 00:00:00

  • Cilostazol for Secondary Prevention of Stroke and Cognitive Decline: Systematic Review and Meta-Analysis.

    abstract:BACKGROUND AND PURPOSE:Cilostazol, a phosphodiesterase 3' inhibitor, is used in Asia-Pacific countries for stroke prevention, but rarely used elsewhere. In addition to weak antiplatelet effects, it stabilizes endothelium, aids myelin repair and astrocyte-neuron energy transfer in laboratory models, effects that may be ...

    journal_title:Stroke

    pub_type: 杂志文章,meta分析

    doi:10.1161/STROKEAHA.120.029454

    authors: McHutchison C,Blair GW,Appleton JP,Chappell FM,Doubal F,Bath PM,Wardlaw JM

    更新日期:2020-08-01 00:00:00

  • Comparative Effectiveness of Rivaroxaban, Apixaban, and Warfarin in Atrial Fibrillation Patients With Polypharmacy.

    abstract:BACKGROUND AND PURPOSE:Comparative effectiveness and safety of oral anticoagulants in patients with atrial fibrillation and high polypharmacy are unknown. METHODS:We used Medicare administrative data to evaluate patients with new atrial fibrillation diagnosis from 2015 to 2017, who initiated an oral anticoagulant with...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.029541

    authors: Mentias A,Heller E,Vaughan Sarrazin M

    更新日期:2020-07-01 00:00:00

  • Prehospital Triage of Acute Stroke Patients During the COVID-19 Pandemic.

    abstract::The coronavirus disease 2019 (COVID-19) pandemic has broad implications on stroke patient triage. Emergency medical services providers have to ensure timely transfer of patients while minimizing the risk of infectious exposure for themselves, their co-workers, and other patients. This statement paper provides a concep...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.030340

    authors: Goyal M,Ospel JM,Southerland AM,Wira C,Amin-Hanjani S,Fraser JF,Panagos P,AHA\/ASA Stroke Council Science Subcommittees: Emergency Neurovascular Care (ENCC), the Telestroke and the Neurovascular Intervention Committees.

    更新日期:2020-07-01 00:00:00

  • Quantitative Histogram Analysis on Intracranial Atherosclerotic Plaques: A High-Resolution Magnetic Resonance Imaging Study.

    abstract:BACKGROUND AND PURPOSE:Intracranial atherosclerosis is one of the main causes of stroke, and high-resolution magnetic resonance imaging provides useful imaging biomarkers related to the risk of ischemic events. This study aims to evaluate differences in histogram features between culprit and nonculprit intracranial ath...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.029062

    authors: Shi Z,Li J,Zhao M,Peng W,Meddings Z,Jiang T,Liu Q,Teng Z,Lu J

    更新日期:2020-07-01 00:00:00

  • Protected Code Stroke: Hyperacute Stroke Management During the Coronavirus Disease 2019 (COVID-19) Pandemic.

    abstract::Background and Purpose- Hyperacute assessment and management of patients with stroke, termed code stroke, is a time-sensitive and high-stakes clinical scenario. In the context of the current coronavirus disease 2019 (COVID-19) pandemic caused by the SARS-CoV-2 virus, the ability to deliver timely and efficacious care ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.029838

    authors: Khosravani H,Rajendram P,Notario L,Chapman MG,Menon BK

    更新日期:2020-06-01 00:00:00

  • Translesional Pressure Gradient Alters Relationship Between Blood Pressure and Recurrent Stroke in Intracranial Stenosis.

    abstract::Background and Purpose- There is debate over an optimal systolic blood pressure (SBP) in secondary stroke prevention of patients with symptomatic intracranial atherosclerotic stenosis (sICAS). We investigated whether translesional pressure gradient across sICAS would alter the relationship between SBP and risk of recu...

    journal_title:Stroke

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1161/STROKEAHA.119.028616

    authors: Feng X,Chan KL,Lan L,Abrigo J,Ip VHL,Soo YOY,Leung TW,Leng X

    更新日期:2020-06-01 00:00:00

  • Stroke Etiology and Thrombus Computed Tomography Characteristics in Patients With Acute Ischemic Stroke: A MR CLEAN Registry Substudy.

    abstract::Background and Purpose- If a relationship between stroke etiology and thrombus computed tomography characteristics exists, assessing these characteristics in clinical practice could serve as a useful additional diagnostic tool for the identification of stroke subtype. Our purpose was to study the association of stroke...

    journal_title:Stroke

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1161/STROKEAHA.119.027749

    authors: Boodt N,Compagne KCJ,Dutra BG,Samuels N,Tolhuisen ML,Alves HCBR,Kappelhof M,Lycklama À Nijeholt GJ,Marquering HA,Majoie CBLM,Lingsma HF,Dippel DWJ,van der Lugt A,Coinvestigators MR CLEAN Registry.

    更新日期:2020-06-01 00:00:00

  • Intraventricular Hemorrhage Clearance in Human Neonatal Cerebrospinal Fluid: Associations With Hydrocephalus.

    abstract::Background and Purpose- Preterm neonates with intraventricular hemorrhage (IVH) are at risk for posthemorrhagic hydrocephalus and poor neurological outcomes. Iron has been implicated in ventriculomegaly, hippocampal injury, and poor outcomes following IVH. We hypothesized that levels of cerebrospinal fluid blood break...

    journal_title:Stroke

    pub_type: 临床试验,杂志文章

    doi:10.1161/STROKEAHA.119.028744

    authors: Mahaney KB,Buddhala C,Paturu M,Morales D,Limbrick DD Jr,Strahle JM

    更新日期:2020-06-01 00:00:00

  • Endovascular Treatment for Acute Ischemic Stroke in Patients on Oral Anticoagulants: Results From the MR CLEAN Registry.

    abstract::Background and Purpose- The use of oral anticoagulants (OAC) is considered a contra-indication for intravenous thrombolytics as acute treatment of ischemic stroke. However, little is known about the risks and benefits of endovascular treatment in patients on prior OAC. We aim to compare outcomes after endovascular tre...

    journal_title:Stroke

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1161/STROKEAHA.119.028675

    authors: Goldhoorn RB,van de Graaf RA,van Rees JM,Lingsma HF,Dippel DWJ,Hinsenveld WH,Postma A,van den Wijngaard I,van Zwam WH,van Oostenbrugge RJ,Roozenbeek B,MR CLEAN Registry Investigators—Group Authors.

    更新日期:2020-06-01 00:00:00

  • PERK (Protein Kinase RNA-Like ER Kinase) Branch of the Unfolded Protein Response Confers Neuroprotection in Ischemic Stroke by Suppressing Protein Synthesis.

    abstract::Background and Purpose- Ischemic stroke impairs endoplasmic reticulum (ER) function, causes ER stress, and activates the unfolded protein response. The unfolded protein response consists of 3 branches controlled by ER stress sensor proteins, which include PERK (protein kinase RNA-like ER kinase). Activated PERK phosph...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.029071

    authors: Wang YC,Li X,Shen Y,Lyu J,Sheng H,Paschen W,Yang W

    更新日期:2020-05-01 00:00:00

  • Collateral Recruitment Is Impaired by Cerebral Small Vessel Disease.

    abstract::Background and Purpose- Cerebral small vessel disease (SVD) is associated with increased stroke risk and poor stroke outcomes. We aimed to evaluate whether chronic SVD burden is associated with poor recruitment of collaterals in large-vessel occlusive stroke. Methods- Consecutive patients with middle cerebral artery o...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.119.027661

    authors: Lin MP,Brott TG,Liebeskind DS,Meschia JF,Sam K,Gottesman RF

    更新日期:2020-05-01 00:00:00

  • Change in Body Weight and Long-Term Risk of Stroke and Death in Healthy Men.

    abstract::Background and Purpose- The importance of weight change for the risk of stroke is not well known. We examined the associations between early- and mid-life weight change and risks of stroke and death during long-term follow-up of healthy men. Methods- We recruited healthy men aged between 40 and 59 years and performed ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.119.027233

    authors: Prestgaard E,Mariampillai J,Engeseth K,Erikssen J,Bodegård J,Liestøl K,Kjeldsen S,Grundvold I,Berge E

    更新日期:2020-05-01 00:00:00

  • Etiologic Workup in Cases of Cryptogenic Stroke: A Systematic Review of International Clinical Practice Guidelines.

    abstract::Background and Purpose- Identifying the etiology of acute ischemic stroke is essential for effective secondary prevention. However, in at least one third of ischemic strokes, existing investigative protocols fail to determine the underlying cause. Establishing etiology is complicated by variation in clinical practice,...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.119.027123

    authors: McMahon NE,Bangee M,Benedetto V,Bray EP,Georgiou RF,Gibson JME,Lane DA,Al-Khalidi AH,Chatterjee K,Chauhan U,Clegg AJ,Lightbody CE,Lip GYH,Sekhar A,Watkins CL

    更新日期:2020-05-01 00:00:00

  • Mobile Stroke Unit Computed Tomography Angiography Substantially Shortens Door-to-Puncture Time.

    abstract::Background and Purpose- Endovascular thrombectomy (ET) door-to-puncture time (DTPT) is a modifiable metric. One of the most important, yet time-consuming steps, is documentation of large vessel occlusion by computed tomography angiography (CTA). We hypothesized that obtaining CTA on board a Mobile Stroke Unit and dire...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.119.028626

    authors: Czap AL,Singh N,Bowry R,Jagolino-Cole A,Parker SA,Phan K,Wang M,Sheth SA,Rajan SS,Yamal JM,Grotta JC

    更新日期:2020-05-01 00:00:00

  • Endovascular Thrombectomy for Acute Ischemic Strokes: Current US Access Paradigms and Optimization Methodology.

    abstract::Background and Purpose- Timely access to endovascular thrombectomy (EVT) centers is vital for best acute ischemic stroke outcomes. Methods- US stroke-treating centers were mapped utilizing geo-mapping and stratified into non-EVT or EVT if they reported ≥1 acute ischemic stroke thrombectomy code in 2017 to Center for M...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.028850

    authors: Sarraj A,Savitz S,Pujara D,Kamal H,Carroll K,Shaker F,Reddy S,Parsha K,Fournier LE,Jones EM,Sharrief A,Martin-Schild S,Grotta J

    更新日期:2020-04-01 00:00:00

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