abstract：BACKGROUND AND PURPOSE:The objective is to compare the effects of high-intensity interval training (HIIT) with long versus short intervals on endurance and motor performance. Their influence on neuroplasticity markers is assessed in the ipsilesional and contralesional cortex and hippocampus since their remodeling could...

journal_title：Stroke

authors： Pin-Barre C,Hugues N,Constans A,Berton E,Pellegrino C,Laurin J

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Patent foramen ovale (PFO) may increase the risk of embolic stroke of undetermined source (ESUS). Guidelines suggest anticoagulation may be more effective than antiplatelets in preventing stroke in patients with ESUS and PFO when interventional closure is not performed. METHODS:Patients with ESU...

journal_title：Stroke

authors： Diener HC,Chutinet A,Easton JD,Granger CB,Kleine E,Marquardt L,Meyerhoff J,Zini A,Sacco RL

更新日期：2021-01-28 00:00:00

abstract：BACKGROUND AND PURPOSE:Preceding infection as an important risk factor for ischemic stroke has been reported but neglected for hemorrhagic stroke, especially in young and middle-aged patients. This study investigates whether newly diagnosed leptospirosis is associated with an increased risk of stroke. METHODS:We ident...

journal_title：Stroke

authors： Li KY,Chou MC,Wei JC,Lin MC,Hung YM,Chang R

更新日期：2021-01-26 00:00:00

abstract：BACKGROUND AND PURPOSE:The role of decompressive hemicraniectomy (DC) in malignant cerebral infarction (MCI) has clearly been established, but little is known about the course of intracranial pressure (ICP) in patients undergoing this surgical measure. In this study, we investigated the role of invasive ICP monitoring ...

journal_title：Stroke

authors： Hernández-Durán S,Meinen L,Rohde V,von der Brelie C

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Lacunar syndromes correlate with a lacunar stroke on imaging in 50% to 60% of cases. Computed tomography perfusion (CTP) is becoming the preferred imaging modality for acute stroke triage. We aimed to estimate the sensitivity, specificity, and predictive values for noncontrast computed tomography...

journal_title：Stroke

authors： Garcia-Esperon C,Visser M,Churilov L,Miteff F,Bivard A,Lillicrap T,Levi CR,Spratt NJ,Parsons MW

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We aimed to investigate the relationship between early NT-proBNP (N-terminal probrain natriuretic peptide) and all-cause death in patients receiving reperfusion therapy, including intravenous thrombolysis and endovascular thrombectomy (EVT). METHODS:This study included 1039 acute ischemic stroke...

journal_title：Stroke

authors： Zhang X,Yan S,Zhong W,Yu Y,Lou M

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Time elapsed from last-known well (LKW) and baseline imaging results are influential on endovascular thrombectomy (EVT) outcomes. METHODS:In a prospective multicenter cohort study of imaging selection for endovascular thrombectomy (SELECT [Optimizing Patient's Selection for Endovascular Treatmen...

journal_title：Stroke

authors： Sarraj A,Hassan AE,Grotta J,Blackburn S,Day A,Abraham M,Sitton C,Dannenbaum M,Cai C,Pujara D,Hicks W,Vora N,Budzik R,Shaker F,Arora A,Riascos RF,Kamal H,Martin-Schild S,Lansberg M,Gupta R,Albers GW,SELECT Invest

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In intracerebral hemorrhage (ICH), preexisting cognitive impairment has been identified as a risk factor for increased mortality and morbidity. However, previous studies examined predominantly White populations; therefore, the prevalence and effect of preICH cognitive impairment has not been stud...

journal_title：Stroke

authors： Sawyer RP,Yim E,Coleman E,Demel SL,Sekar P,Woo D

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Ischemic injury triggers multiple pathological responses in the brain tissue, including spreading depolarizations across the cerebral cortex (cortical spreading depolarizations [CSD]). Microglia have been recently shown to play a significant role in the propagation of CSD. However, the intracellu...

journal_title：Stroke

authors： Liu L,Kearns KN,Eli I,Sharifi KA,Soldozy S,Carlson EW,Scott KW,Sluzewski MF,Acton ST,Stauderman KA,Kalani MYS,Park M,Tvrdik P

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Mechanical thrombectomy (MT) is the recommended treatment for acute ischemic stroke caused by anterior circulation large vessel occlusion. However, despite a high rate of reperfusion, the clinical response to successful MT remains highly variable in the early time window where optimal imaging sel...

journal_title：Stroke

authors： Olivot JM,Albucher JF,Guenego A,Thalamas C,Mlynash M,Rousseau V,Drif A,Christensen S,Sommet A,Viguier A,Darcourt J,Calvière L,Menegon P,Raposo N,Januel AC,Bonneville F,Tourdias T,Mazighi M,Sibon I,Albers GW,Cognar

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We aim to evaluate if good collateral flow (CF) modifies endovascular therapy (EVT) efficacy on large-vessel stroke. To do that, we used final degree of reperfusion and number of device-passes performed, factors previously associated with better functional outcome, as main outcome measures. METH...

journal_title：Stroke

authors： García-Tornel Á,Ciolli L,Rubiera M,Requena M,Muchada M,Pagola J,Rodriguez-Luna D,Deck M,Juega J,Rodríguez-Villatoro N,Boned S,Olivé-Gadea M,Sanjuan E,Tomasello A,Piñana C,Hernández D,Álvarez-Sabin J,Molina CA,Ribó M

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A recent study proposed that thrombus perviousness (TP)-the degree to which contrast agents penetrate the thrombus in an occluded vessel measured on noncontrast computed tomography (NCCT) and CT angiography-may be associated with cardioembolic stroke cause with high specificity. Our aim was to in...

journal_title：Stroke

authors： Kufner A,Erdur H,Endres M,Nolte CH,Scheel M,Schlemm L

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We aimed to determine whether lobar cerebellar microbleeds or concomitant lobar cerebellar and deep microbleeds, in the presence of lobar cerebral microbleeds, attribute to underlying advanced cerebral amyloid angiopathy pathology or hypertensive arteriopathy. METHODS:We categorized 71 patients ...

journal_title：Stroke

authors： Jung YH,Jang H,Park SB,Choe YS,Park Y,Kang SH,Lee JM,Kim JS,Kim J,Kim JP,Kim HJ,Na DL,Seo SW

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We aim to investigate whether histopathologic examination of thrombi retrieved from acute ischemic stroke patients undergoing endovascular treatment could distinguish cancer-related stroke from other etiologies. METHODS:Thrombi from patients undergoing endovascular treatment were analyzed. The e...

journal_title：Stroke

authors： Fu CH,Chen CH,Lin YH,Lee CW,Tsai LK,Tang SC,Shun CT,Jeng JS

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although the efficacy of endovascular treatment (EVT) in patients with anterior circulation ischemic stroke (AIS) is well documented, early neurological deterioration after EVT remains a serious issue associated with poor outcome. Besides obvious causes, such as lack of reperfusion, procedural co...

journal_title：Stroke

authors： Girot JB,Richard S,Gariel F,Sibon I,Labreuche J,Kyheng M,Gory B,Dargazanli C,Maier B,Consoli A,Daumas-Duport B,Lapergue B,Bourcier R,ETIS Investigators*.

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Post hoc analyses of randomized controlled clinical trials evaluating mechanical thrombectomy have suggested that admission-to-groin-puncture (ATG) delays are associated with reduced reperfusion rates. Purpose of this analysis was to validate this association in a real-world cohort and to find as...

journal_title：Stroke

authors： Kaesmacher J,Maamari B,Meinel TR,Piechowiak EI,Mosimann PJ,Mordasini P,Goeldlin M,Arnold M,Dobrocky T,Boeckh-Behrens T,Berndt M,Michel P,Requena M,Benali A,Pierot L,Mendes Pereira V,Boulouis G,Brehm A,Sporns PB,Ospe

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Symptomatic hemorrhage contributes to an increased risk of repeated bleeding and morbidity in cerebral cavernous malformation (CCM). A better understanding of morbidity after CCM hemorrhage would be helpful to identify patients of higher risk for unfavorable outcome and tailor individualized mana...

journal_title：Stroke

authors： Ma L,Zhang S,Li Z,Wu CX,Wang Z,Zhan L,Hao Q,Wang H,Ye X,Chen X,Liu YO,Wang S,Zhao YL

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Do children have an increased risk for brain arteriovenous malformation (AVM) recurrence compared with adults and does this risk vary depending on initial presentation with AVM rupture? METHODS:We retrospectively studied 115 patients initially presenting with brain AVM under age 25 years who und...

journal_title：Stroke

authors： Copelan A,Drocton G,Caton MT,Smith ER,Cooke DL,Nelson J,Abla AA,Fox C,Amans MR,Dowd CF,Halbach VV,Higashida RT,Lawton MT,Kim H,Fullerton HJ,Gupta N,Hetts SW,UCSF Center For Cerebrovascular Research and UCSF Pediatric Br

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Anecdotal evidence suggests that the coronavirus disease 2019 (COVID-19) pandemic mitigation efforts may inadvertently discourage patients from seeking treatment for stroke with resultant increased morbidity and mortality. Analysis of regional data, while hospital capacities for acute stroke care...

journal_title：Stroke

authors： Hsiao J,Sayles E,Antzoulatos E,Stanton RJ,Sucharew H,Broderick JP,Demel SL,Flaherty ML,Grossman AW,Kircher C,Kreitzer N,Peariso K,Prestigiacomo CJ,Shirani P,Walsh KB,Lampton H,Adeoye O,Khatri P

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Identification of acute ischemic stroke (AIS) cause is crucial for guidance of secondary prevention. Previous studies have yielded inconsistent results regarding possible correlations between AIS cause and thrombus composition, as assessed by semiquantitative histological analysis. Here, we perfo...

journal_title：Stroke

authors： Di Meglio L,Desilles JP,Solonomenjanahary M,Labreuche J,Ollivier V,Dupont S,Deschildre C,Maacha MB,Consoli A,Lapergue B,Piotin M,Blanc R,Ho-Tin-Noe B,Mazighi M,compoCLOT study group†.

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Brain atrophy can be regarded as an end-organ effect of cumulative cardiovascular risk factors. Accelerated brain atrophy is described following ischemic stroke, but it is not known whether atrophy rates vary over the poststroke period. Examining rates of brain atrophy allows the identification o...

journal_title：Stroke

authors： Brodtmann A,Khlif MS,Egorova N,Veldsman M,Bird LJ,Werden E

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Enlarged perivascular spaces (EPVS) have been associated with aging, increased stroke risk, decreased cognitive function, and vascular dementia. However, the relationship of EPVS with age-related neuropathologies is not well understood. Therefore, the purpose of this study was to assess the neuro...

journal_title：Stroke

authors： Javierre-Petit C,Schneider JA,Kapasi A,Makkinejad N,Tamhane AA,Leurgans SE,Mehta RI,Barnes LL,Bennett DA,Arfanakis K

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Delayed cerebral ischemia (DCI) is the most important cause for a poor clinical outcome after a subarachnoid hemorrhage. The aim of this study was to assess whether goal-directed hemodynamic therapy (GDHT), as compared to standard clinical care, reduces the rate of DCI after subarachnoid hemorrha...

journal_title：Stroke

authors： Anetsberger A,Gempt J,Blobner M,Ringel F,Bogdanski R,Heim M,Schneider G,Meyer B,Schmid S,Ryang YM,Wostrack M,Schneider J,Martin J,Ehrhardt M,Jungwirth B

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Disabling anxiety affects a quarter of stroke survivors but access to treatment is poor. We developed a telemedicine model for delivering guided self-help cognitive behavioral therapy (CBT) for anxiety after stroke (TASK-CBT). We aimed to evaluate the feasibility of TASK-CBT in a randomized contr...

journal_title：Stroke

authors： Chun HY,Carson AJ,Tsanas A,Dennis MS,Mead GE,Calabria C,Whiteley WN

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke incidence and mortality are declining rapidly in developed countries. Little data on ethnic-specific stroke recurrence trends exist. Fourteen-year stroke recurrence trend estimates were evaluated in Mexican Americans and non-Hispanic whites in a population-based study. METHODS:Recurrent s...

journal_title：Stroke

authors： Sozener CB,Lisabeth LD,Shafie-Khorassani F,Kim S,Zahuranec DB,Brown DL,Skolarus LE,Burke JF,Kerber KA,Meurer WJ,Case E,Morgenstern LB

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cilostazol, a phosphodiesterase 3' inhibitor, is used in Asia-Pacific countries for stroke prevention, but rarely used elsewhere. In addition to weak antiplatelet effects, it stabilizes endothelium, aids myelin repair and astrocyte-neuron energy transfer in laboratory models, effects that may be ...

journal_title：Stroke

authors： McHutchison C,Blair GW,Appleton JP,Chappell FM,Doubal F,Bath PM,Wardlaw JM

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Comparative effectiveness and safety of oral anticoagulants in patients with atrial fibrillation and high polypharmacy are unknown. METHODS:We used Medicare administrative data to evaluate patients with new atrial fibrillation diagnosis from 2015 to 2017, who initiated an oral anticoagulant with...

journal_title：Stroke

authors： Mentias A,Heller E,Vaughan Sarrazin M

更新日期：2020-07-01 00:00:00

abstract：:The coronavirus disease 2019 (COVID-19) pandemic has broad implications on stroke patient triage. Emergency medical services providers have to ensure timely transfer of patients while minimizing the risk of infectious exposure for themselves, their co-workers, and other patients. This statement paper provides a concep...

journal_title：Stroke

authors： Goyal M,Ospel JM,Southerland AM,Wira C,Amin-Hanjani S,Fraser JF,Panagos P,AHA\/ASA Stroke Council Science Subcommittees: Emergency Neurovascular Care (ENCC), the Telestroke and the Neurovascular Intervention Committees.

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intracranial atherosclerosis is one of the main causes of stroke, and high-resolution magnetic resonance imaging provides useful imaging biomarkers related to the risk of ischemic events. This study aims to evaluate differences in histogram features between culprit and nonculprit intracranial ath...

journal_title：Stroke

authors： Shi Z,Li J,Zhao M,Peng W,Meddings Z,Jiang T,Liu Q,Teng Z,Lu J

更新日期：2020-07-01 00:00:00

abstract：:Background and Purpose- Hyperacute assessment and management of patients with stroke, termed code stroke, is a time-sensitive and high-stakes clinical scenario. In the context of the current coronavirus disease 2019 (COVID-19) pandemic caused by the SARS-CoV-2 virus, the ability to deliver timely and efficacious care ...

journal_title：Stroke

authors： Khosravani H,Rajendram P,Notario L,Chapman MG,Menon BK

更新日期：2020-06-01 00:00:00

abstract：:Background and Purpose- There is debate over an optimal systolic blood pressure (SBP) in secondary stroke prevention of patients with symptomatic intracranial atherosclerotic stenosis (sICAS). We investigated whether translesional pressure gradient across sICAS would alter the relationship between SBP and risk of recu...

journal_title：Stroke

authors： Feng X,Chan KL,Lan L,Abrigo J,Ip VHL,Soo YOY,Leung TW,Leng X

更新日期：2020-06-01 00:00:00

abstract：:Background and Purpose- If a relationship between stroke etiology and thrombus computed tomography characteristics exists, assessing these characteristics in clinical practice could serve as a useful additional diagnostic tool for the identification of stroke subtype. Our purpose was to study the association of stroke...

journal_title：Stroke

authors： Boodt N,Compagne KCJ,Dutra BG,Samuels N,Tolhuisen ML,Alves HCBR,Kappelhof M,Lycklama À Nijeholt GJ,Marquering HA,Majoie CBLM,Lingsma HF,Dippel DWJ,van der Lugt A,Coinvestigators MR CLEAN Registry.

更新日期：2020-06-01 00:00:00

abstract：:Background and Purpose- Preterm neonates with intraventricular hemorrhage (IVH) are at risk for posthemorrhagic hydrocephalus and poor neurological outcomes. Iron has been implicated in ventriculomegaly, hippocampal injury, and poor outcomes following IVH. We hypothesized that levels of cerebrospinal fluid blood break...

journal_title：Stroke

authors： Mahaney KB,Buddhala C,Paturu M,Morales D,Limbrick DD Jr,Strahle JM

更新日期：2020-06-01 00:00:00

abstract：:Background and Purpose- The use of oral anticoagulants (OAC) is considered a contra-indication for intravenous thrombolytics as acute treatment of ischemic stroke. However, little is known about the risks and benefits of endovascular treatment in patients on prior OAC. We aim to compare outcomes after endovascular tre...

journal_title：Stroke

authors： Goldhoorn RB,van de Graaf RA,van Rees JM,Lingsma HF,Dippel DWJ,Hinsenveld WH,Postma A,van den Wijngaard I,van Zwam WH,van Oostenbrugge RJ,Roozenbeek B,MR CLEAN Registry Investigators—Group Authors.

更新日期：2020-06-01 00:00:00

abstract：:Background and Purpose- Ischemic stroke impairs endoplasmic reticulum (ER) function, causes ER stress, and activates the unfolded protein response. The unfolded protein response consists of 3 branches controlled by ER stress sensor proteins, which include PERK (protein kinase RNA-like ER kinase). Activated PERK phosph...

journal_title：Stroke

authors： Wang YC,Li X,Shen Y,Lyu J,Sheng H,Paschen W,Yang W

更新日期：2020-05-01 00:00:00

abstract：:Background and Purpose- Cerebral small vessel disease (SVD) is associated with increased stroke risk and poor stroke outcomes. We aimed to evaluate whether chronic SVD burden is associated with poor recruitment of collaterals in large-vessel occlusive stroke. Methods- Consecutive patients with middle cerebral artery o...

journal_title：Stroke

authors： Lin MP,Brott TG,Liebeskind DS,Meschia JF,Sam K,Gottesman RF

更新日期：2020-05-01 00:00:00

abstract：:Background and Purpose- The importance of weight change for the risk of stroke is not well known. We examined the associations between early- and mid-life weight change and risks of stroke and death during long-term follow-up of healthy men. Methods- We recruited healthy men aged between 40 and 59 years and performed ...

journal_title：Stroke

authors： Prestgaard E,Mariampillai J,Engeseth K,Erikssen J,Bodegård J,Liestøl K,Kjeldsen S,Grundvold I,Berge E

更新日期：2020-05-01 00:00:00

abstract：:Background and Purpose- Identifying the etiology of acute ischemic stroke is essential for effective secondary prevention. However, in at least one third of ischemic strokes, existing investigative protocols fail to determine the underlying cause. Establishing etiology is complicated by variation in clinical practice,...

journal_title：Stroke

authors： McMahon NE,Bangee M,Benedetto V,Bray EP,Georgiou RF,Gibson JME,Lane DA,Al-Khalidi AH,Chatterjee K,Chauhan U,Clegg AJ,Lightbody CE,Lip GYH,Sekhar A,Watkins CL

更新日期：2020-05-01 00:00:00

abstract：:Background and Purpose- Endovascular thrombectomy (ET) door-to-puncture time (DTPT) is a modifiable metric. One of the most important, yet time-consuming steps, is documentation of large vessel occlusion by computed tomography angiography (CTA). We hypothesized that obtaining CTA on board a Mobile Stroke Unit and dire...

journal_title：Stroke

authors： Czap AL,Singh N,Bowry R,Jagolino-Cole A,Parker SA,Phan K,Wang M,Sheth SA,Rajan SS,Yamal JM,Grotta JC

更新日期：2020-05-01 00:00:00

abstract：:Background and Purpose- Timely access to endovascular thrombectomy (EVT) centers is vital for best acute ischemic stroke outcomes. Methods- US stroke-treating centers were mapped utilizing geo-mapping and stratified into non-EVT or EVT if they reported ≥1 acute ischemic stroke thrombectomy code in 2017 to Center for M...

journal_title：Stroke

authors： Sarraj A,Savitz S,Pujara D,Kamal H,Carroll K,Shaker F,Reddy S,Parsha K,Fournier LE,Jones EM,Sharrief A,Martin-Schild S,Grotta J

更新日期：2020-04-01 00:00:00