Cilostazol for Secondary Prevention of Stroke and Cognitive Decline: Systematic Review and Meta-Analysis.

abstract：BACKGROUND AND PURPOSE:The pivotal National Institute of Neurological Disorders and Stroke recombinant tissue plasminogen activator trials excluded patients with ischemic stroke with specific minor presentations or rapidly improving symptoms. The recombinant tissue plasminogen activator product label notes that its use...

journal_title：Stroke

authors： Khatri P,Kleindorfer DO,Yeatts SD,Saver JL,Levine SR,Lyden PD,Moomaw CJ,Palesch YY,Jauch EC,Broderick JP

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The Montreal Cognitive Assessment (MoCA) and Addenbrooke's Cognitive Examination-Revised (ACE-R) are proposed as short cognitive tests for use after stroke, but there are few published validations against a neuropsychological battery. We studied the relationship between MoCA, ACE-R, Mini-Mental S...

journal_title：Stroke

authors： Pendlebury ST,Mariz J,Bull L,Mehta Z,Rothwell PM

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The collagen alpha2(I) gene (COL1A2) on chromosome 7q22.1, a positional and functional candidate for intracranial aneurysm (IA), was extensively screened for susceptibility in Japanese IA patients. METHODS:Twenty-one single nucleotide polymorphisms (SNPs) of COL1A2 were genotyped in genomic DNA ...

journal_title：Stroke

authors： Yoneyama T,Kasuya H,Onda H,Akagawa H,Hashiguchi K,Nakajima T,Hori T,Inoue I

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Lacunar ischemic stroke accounts for 25% of all ischemic strokes, but the exact etiology is unknown. Numerous pathophysiologies have been proposed, including atheroma and endothelial dysfunction. Models of any of these pathological features would aid understanding of the etiology and help develop...

journal_title：Stroke

authors： Bailey EL,McCulloch J,Sudlow C,Wardlaw JM

更新日期：2009-06-01 00:00:00

abstract：:Background and Purpose- Many patients with acute ischemic stroke are not eligible for thrombolysis or mechanical reperfusion therapies due to contraindications, inaccessible vascular occlusions, late presentation, or large infarct core. Sphenopalatine ganglion (SPG) stimulation to enhance collateral flow and stabilize...

journal_title：Stroke

authors： Bornstein NM,Saver JL,Diener HC,Gorelick PB,Shuaib A,Solberg Y,Devlin T,Leung T,Molina CA,ImpACT-24A Investigators † .,ImpACT-24A Investigators include the Site Principal Investigators, DSMB members, and the Site Co-Investigators lis

更新日期：2019-05-23 00:00:00

abstract：BACKGROUND AND PURPOSE:Experimental and clinical data suggest that insonation of echo-contrast agents with high acoustical power produces disintegration of microbubbles, resulting in a pseudo-Doppler phenomenon called stimulated acoustic emission (SAE). The purpose of this study was to investigate whether SAE might be ...

journal_title：Stroke

authors： Pohl C,Tiemann K,Schlosser T,Becher H

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To compare the utility of contrast-enhanced MR Angiography (CE-MRA) with digital subtraction angiography (DSA) after endovascular treatment of intracranial aneurysms with Guglielmi detachable coils. METHODS:From April 1999 to August 2002, 106 patients with 107 aneurysms treated by endovascular c...

journal_title：Stroke

authors： Gauvrit JY,Leclerc X,Caron S,Taschner CA,Lejeune JP,Pruvo JP

更新日期：2006-04-01 00:00:00

abstract：:Platelet-activating factor is a potent mediator of inflammation, which has untoward effects on cerebrovascular and neural elements. While several investigators have reported attenuation of ischemic damage after treatment with antagonists of platelet-activating factor, no study has proved endogenous production of plate...

journal_title：Stroke

authors： Lindsberg PJ,Yue TL,Frerichs KU,Hallenbeck JM,Feuerstein G

更新日期：1990-10-01 00:00:00

abstract：:Glycosylated hemoglobin concentration (GHb), which is considered an indication of glycemia over the preceding several months, was examined in 50 patients hospitalized for recent stroke or transient ischemic attacks (TIA), and compared to that in several reference populations. Patients with stroke or TIA had GHb (mean ...

journal_title：Stroke

authors： Riddle MC,Hart J

更新日期：1982-05-01 00:00:00

abstract：:We report the case of a young man with recurrent posterior circulation strokes over the course of 6 years. Standard stroke evaluation was unremarkable until careful review of catheter angiogram and CT angiogram images revealed a bony protuberance from the occiput impinging on the left vertebral artery. Local vessel in...

journal_title：Stroke

authors： Cronin CA,Aldrich EF,Kittner SJ

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke produces diaschisis in adjacent and connected regions. The sequential changes in diaschisis over time and the relationship of regions of diaschisis to functional cortical areas and regions of poststroke neuroplasticity have not been determined. METHODS:Small cortical strokes were produced...

journal_title：Stroke

authors： Carmichael ST,Tatsukawa K,Katsman D,Tsuyuguchi N,Kornblum HI

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Transorbital sonography may help establish diagnosis of central retinal artery occlusion (CRAO). Next to Doppler sonographic proof of CRAO, an intra-arterial spot sign can be detected in some cases. We hypothesized that it reflects calcified components. It may be associated with embolization from...

journal_title：Stroke

authors： Nedelmann M,Graef M,Weinand F,Wassill KH,Kaps M,Lorenz B,Tanislav C

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Many studies have reported frequent cognitive deficits associated with subarachnoid hemorrhage (SAH) and aneurysm repair. One study found more severe cognitive deficits after clipping than coiling of aneurysms, raising the possibility that deficits are due to surgery instead of SAH itself. This p...

journal_title：Stroke

authors： Tuffiash E,Tamargo RJ,Hillis AE

更新日期：2003-09-01 00:00:00

abstract：:Survival and recurrences after stroke were assessed prospectively in a general population sample of 5184 subjects followed biennially for 26 years. Initial strokes occurred in 198 men and 196 women. There were 84 second and 27 third strokes and 223 deaths reported. Thirty day case-fatality rates for initial strokes we...

journal_title：Stroke

authors： Sacco RL,Wolf PA,Kannel WB,McNamara PM

更新日期：1982-05-01 00:00:00

abstract：:Cerebral blood flow and clinical parameters were studied in 30 stroke patients at 15th, 30th, 60th, 90th days after the cerebral insult (Xenon 133 inhalation method). The clinical improvement was not accompanied by a progressive normalization of the CBF at rest. No relationship was found between the clinical data and ...

journal_title：Stroke

authors： Demeurisse G,Verhas M,Capon A,Paternot J

更新日期：1983-01-01 00:00:00

abstract：:Experimental subarachnoid hemorrhage was induced in 52 adult male Wistar rats by microsurgical transclival basilar artery puncture. Telencephalic blood flow measured in 24 rats with subarachnoid hemorrhage was compared with that in 23 sham-operated rats and 10 unoperated control rats using the [14C]butanol indicator f...

journal_title：Stroke

authors： Kader A,Krauss WE,Onesti ST,Elliott JP,Solomon RA

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Treatment with the ketone body precursor 1,3-butanediol has been suggested to ameliorate hypoxic/ischemic brain damage. Butanediol could provide an alternative energy substrate for the brain, thereby decreasing the amount of glycolytically produced lactate. Hyperglycemia aggravates brain damage a...

journal_title：Stroke

authors： Lundgren J,Smith ML,Mans AM,Siesjö BK

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of our study was to compare outcome and its determinants in familial subarachnoid hemorrhage and in sporadic subarachnoid hemorrhage in a large and well-documented patient population. METHODS:Patients with aneurysmal subarachnoid hemorrhage (SAH) treated at the Department of Neurosurgery...

journal_title：Stroke

authors： Ronkainen A,Niskanen M,Piironen R,Hernesniemi J

更新日期：1999-05-01 00:00:00

abstract：:Perforating branches of the middle cerebral arteries (MCA) were examined on the forebrain hemispheres of fourteen human brains. It was noticed that their intracerebral segments arose from the MCA main trunk, and its terminal and collateral (cortical) branches. They terminated in certain parts of the basal ganglia and ...

journal_title：Stroke

authors： Marinkovic SV,Milisavljevic MM,Kovacevic MS,Stevic ZD

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke is an important cause of death and disability among children. Clinical trials for childhood stroke require a valid and reliable acute clinical stroke scale. We evaluated interrater reliability (IRR) of a pediatric adaptation of the National Institutes of Health Stroke Scale. METHODS:The p...

journal_title：Stroke

authors： Ichord RN,Bastian R,Abraham L,Askalan R,Benedict S,Bernard TJ,Beslow L,Deveber G,Dowling M,Friedman N,Fullerton H,Jordan L,Kan L,Kirton A,Amlie-Lefond C,Licht D,Lo W,McClure C,Pavlakis S,Smith SE,Tan M,Kasner S

更新日期：2011-03-01 00:00:00

abstract：:Background and Purpose- Intracranial thrombi can be characterized according to their permeability as measured by contrast agent penetration. Thrombus composition and its associated pathogenesis are important factors affecting treatment and secondary prevention. We aimed to explore the histopathologic factors explainin...

journal_title：Stroke

authors： Berndt M,Friedrich B,Maegerlein C,Moench S,Hedderich D,Lehm M,Zimmer C,Straeter A,Poppert H,Wunderlich S,Schirmer L,Oberdieck P,Kaesmacher J,Boeckh-Behrens T

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to evaluate the diagnostic accuracy of ultrasound criteria for recanalization during real-time transcranial Doppler monitoring of intra-arterial reperfusion procedures in acute ischemic stroke patients in an international, multicenter study. METHODS:Consecutive acute ischemic stroke pa...

journal_title：Stroke

authors： Tsivgoulis G,Ribo M,Rubiera M,Vasdekis SN,Barlinn K,Athanasiadis D,Bavarsad Shahripour R,Giannopoulos S,Stamboulis E,Harrigan MR,Molina CA,Alexandrov AV

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Therapeutic temperature modulation is widely used in neurocritical care but commonly causes shivering, which can hamper the cooling process and result in increases in systemic metabolism. We sought to validate a grading scale to assist in the monitoring and control of shivering. METHODS:A simple...

journal_title：Stroke

authors： Badjatia N,Strongilis E,Gordon E,Prescutti M,Fernandez L,Fernandez A,Buitrago M,Schmidt JM,Ostapkovich ND,Mayer SA

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to investigate whether the combination of blood flow measurements in the major cerebral arteries and measurements of cerebral metabolism can provide new insight into the hemodynamic effect of carotid lesions in patients with severe stenosis (> 70% reduction in diameter) of the internal ...

journal_title：Stroke

authors： van der Grond J,Eikelboom BC,Mali WP

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The shape and exact size of lacunar infarcts have been investigated only postmortem. Recent imaging techniques based on triangulation and connectivity can now be used for 3D segmentation of cerebral lesions. The shape and size of lacunar infarcts was investigated using these techniques in 10 cere...

journal_title：Stroke

authors： Hervé D,Mangin JF,Molko N,Bousser MG,Chabriat H

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Outcome after mechanical thrombectomy for ischemic stroke may be influenced by blood pressure (BP). This study aims to assess the association of BP changes during general anesthesia versus conscious sedation with functional outcome after mechanical thrombectomy. METHODS:SIESTA (Sedation vs Intub...

journal_title：Stroke

authors： Schönenberger S,Uhlmann L,Ungerer M,Pfaff J,Nagel S,Klose C,Bendszus M,Wick W,Ringleb PA,Kieser M,Möhlenbruch MA,Bösel J

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Emboli and proinflammatory mediators are suspected of generating cerebral edema after coronary surgery. In contrast to cardiopulmonary bypass (CPB), off-pump coronary artery bypass surgery (OPCAB) reduces microemboli count and proinflammatory mediator release but carries the risk of hemodynamic i...

journal_title：Stroke

authors： Bierbach B,Meier M,Kasper-König W,Heimann A,Alessandri B,Horstick G,Oelert H,Kempski O

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Deep intracerebral hemorrhage (ICH) and lacunar infarcts are the result of small vessel disease, whereas nonlacunar infarcts are often caused by large artery atherosclerosis or cardiac embolism. We hypothesized that patients with deep ICH and lacunar infarcts have similar retinal microvascular si...

journal_title：Stroke

authors： Baker ML,Hand PJ,Liew G,Wong TY,Rochtchina E,Mitchell P,Lindley RI,Hankey GJ,Wang JJ,Multi-Centre Retinal Stroke Study Group.

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Despite its high prevalence in stroke survivors, there is little clinical research on bowel dysfunction in this population. This is the first randomized controlled trial to evaluate treatment of constipation and fecal incontinence in stroke survivors. METHODS:Stroke patients with constipation or...

journal_title：Stroke

authors： Harari D,Norton C,Lockwood L,Swift C

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Based on thrombus location and nature and anatomic features of aorta and cerebral arteries, we hypothesized that cardiogenic embolisms (CE) and aortogenic embolisms (AE) might have different right-left propensity and lesion patterns. METHODS:We retrospectively reviewed patients with acute ischem...

journal_title：Stroke

authors： Kim HJ,Song JM,Kwon SU,Kim BJ,Kang DH,Song JK,Kim JS,Kang DW

更新日期：2011-08-01 00:00:00