Early NT-ProBNP (N-Terminal Probrain Natriuretic Peptide) Elevation Predicts Malignant Edema and Death After Reperfusion Therapy in Acute Ischemic Stroke Patients.

abstract：BACKGROUND AND PURPOSE:Despite the reported functional recovery in transplanted stroke models and patients, the mechanism of action underlying stem cell therapy remains not well understood. Here, we examined the role of stem cell-mediated vascular repair in stroke. METHODS:Adult rats were exposed to transient occlusio...

journal_title：Stroke

authors： Ishikawa H,Tajiri N,Shinozuka K,Vasconcellos J,Kaneko Y,Lee HJ,Mimura O,Dezawa M,Kim SU,Borlongan CV

更新日期：2013-12-01 00:00:00

abstract：:Background and Purpose- In this era of endovascular therapy (EVT) with early, complete recanalization and reperfusion, we have observed an even more rapid apparent diffusion coefficient (ADC) normalization within the acute ischemic lesion compared with the natural history or IV-tPA-treated patient. In this study, we a...

journal_title：Stroke

authors： Hsia AW,Luby M,Cullison K,Burton S,Armonda R,Liu AH,Leigh R,Nadareishvili Z,Benson RT,Lynch JK,Latour LL

更新日期：2019-08-01 00:00:00

abstract：:Platelet activating factor, a potent inducer of in vivo platelet activation and thrombosis, has been shown to be excessively active in acute ischemic stroke patients. Therefore, we studied the effect of aspirin/dipyridamole therapy in inhibiting platelet activating factor-induced platelet activation in acute ischemic ...

journal_title：Stroke

authors： Joseph R,Welch KM,D'Andrea G

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Few cohort studies have examined the association of carotid intima-media thickness (IMT) and plaque characteristics with the risk of stroke in apparently healthy persons. We examined the relationship of carotid IMT and the surface, morphology, and calcification of carotid plaques with the inciden...

journal_title：Stroke

authors： Kitamura A,Iso H,Imano H,Ohira T,Okada T,Sato S,Kiyama M,Tanigawa T,Yamagishi K,Shimamoto T

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an inherited small-artery disease that clinically involves only the brain. Particularly early in the disease, patients can show substantial or complete recovery after individual strokes. Cortic...

journal_title：Stroke

authors： Reddy H,De Stefano N,Mortilla M,Federico A,Matthews PM

更新日期：2002-02-01 00:00:00

abstract：:A woman who presented with a subarachnoid hemorrhage secondary to a ruptured anterior spinal artery aneurysm of the spinal cord is reported. While this is the first report of a ruptured aneurysm of the anterior spinal artery with angiographic confirmation, it emphasizes that occasionally subarachnoid hemorrhage may be...

journal_title：Stroke

authors： Vincent FM

更新日期：1981-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Previous work has shown that rates of cerebral microemboli downstream of high-grade internal carotid artery stenosis are higher in recently symptomatic compared with asymptomatic patients. In addition, microembolic rates decline after carotid endarterectomy. We conducted a prospective investigati...

journal_title：Stroke

authors： Sitzer M,Müller W,Siebler M,Hort W,Kniemeyer HW,Jäncke L,Steinmetz H

更新日期：1995-07-01 00:00:00

abstract：:Background and Purpose- High-resolution vessel wall magnetic resonance imaging is a promising technique for assessing wall structures of unruptured intracranial aneurysms (UIAs). However, the relationship between aneurysmal high-resolution vessel wall magnetic resonance imaging features and their histopathologic mecha...

journal_title：Stroke

authors： Quan K,Song J,Yang Z,Wang D,An Q,Huang L,Liu P,Li P,Tian Y,Zhou L,Zhu W

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke mortality is decreasing in Sweden, as is the case in other Western European countries. However, both decreases and increases have been reported in Sweden for persons younger than age 65 years. The aim of this study was to compare the incidence of stroke in Sweden between the periods 1989 a...

journal_title：Stroke

authors： Medin J,Nordlund A,Ekberg K,Swedish Hospital Discharge Register.

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The lipid peroxidation inhibitor U-101033E was examined for effects on cerebral blood flow (CBF), cortical tissue hemoglobin oxygen saturation (HbSo2), and neuronal damage. METHODS:Fifteen minutes of global cerebral ischemia was induced by two-vessel occlusion and hypobaric hypotension. Wistar r...

journal_title：Stroke

authors： Soehle M,Heimann A,Kempski O

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Chinese patients largely experience acute ischemic stroke (AIS) because of large artery atherosclerosis rather than cardioembolism, and whether tirofiban is safe and effective in these patients treated with endovascular thrombectomy (ET) is unknown. This study evaluated the safety and efficacy of...

journal_title：Stroke

authors： Zhao W,Che R,Shang S,Wu C,Li C,Wu L,Chen J,Duan J,Song H,Zhang H,Ling F,Wang Y,Liebeskind D,Feng W,Ji X

更新日期：2017-12-01 00:00:00

abstract：:True, three-dimensional proton nuclear magnetic resonance imaging at 0.147 tesla was performed postmortem on 2 patients embodying various stroke syndromes, including chronic (4 and 15 years) infarction, subacute (within 1 week) bland infarction, acute (2 days) hemorrhagic infarction, and hematoma secondary to ruptured...

journal_title：Stroke

authors： DeWitt LD,Kistler JP,Miller DC,Richardson EP Jr,Buonanno FS

更新日期：1987-03-01 00:00:00

abstract：:To determine the efficacy of calcium channel blockers in preserving neurologic function after central nervous system ischemia, we studied three such agents in two animal models. We treated rabbits after inducing ischemia in the brain with intra-arterial microspheres and in the spinal cord using a removable aortic occl...

journal_title：Stroke

authors： Lyden PD,Zivin JA,Kochhar A,Mazzarella V

更新日期：1988-08-01 00:00:00

abstract：:Adenylate cyclase activity was investigated in either homogenate or particulate fractions from the frontal cerebral cortex of the gerbil following five experimental conditions of bilateral ischemia. After periods of 15 min ischemia, 15 min ischemia plus 15 min of recirculation or 60 min ischemia the enzyme generally d...

journal_title：Stroke

authors： Taylor MD,Palmer GC,Callahan AS 3rd

更新日期：1984-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The role of the cerebral microcirculation in delayed ischemia after subarachnoid hemorrhage remains obscure. To test the hypothesis that cerebral arterioles have a reduced capacity to dilate after subarachnoid hemorrhage, we studied the microvascular responses to papaverine (PPV) in patients unde...

journal_title：Stroke

authors： Pennings FA,Albrecht KW,Muizelaar JP,Schuurman PR,Bouma GJ

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Sonothrombolysis is a new treatment approach in acute ischemic stroke. The results of a monocenter, randomized clinical study are presented. METHODS:Subjects with acute middle cerebral artery main stem occlusion were randomized into a target group receiving 1-hour transcranial continuous insonat...

journal_title：Stroke

authors： Eggers J,König IR,Koch B,Händler G,Seidel G

更新日期：2008-05-01 00:00:00

abstract：:Neurogenically caused cardiac arrhythmias and their correlation to lesions within the central nervous system were examined prospectively in 54 patients with spontaneous intracerebral hemorrhage. All patients were examined neurologically daily for 3 weeks, with special attention given to signs of brainstem compression ...

journal_title：Stroke

authors： Stober T,Sen S,Anstätt T,Bette L

更新日期：1988-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke community surveillance projects often focus on hospital data rates. We hypothesized that not including strokes which occurred in nursing homes or at home would differentially affect race/ethnic stroke rates. METHODS:Texas vital statistics data were studied to compare age-specific (45 to 5...

journal_title：Stroke

authors： Wein TH,Smith MA,Morgenstern LB

更新日期：1999-08-01 00:00:00

abstract：:In patients with subarachnoid hemorrhage, particularly hemorrhage due to aneurysmal rupture, there was a positive significant relation between angiographic vessel constriction and vessel pathology (angiopathy). Furthermore, there was a positive relationship between post-hemorrhage survival time and the severity of ang...

journal_title：Stroke

authors： Smith RR,Clower BR,Peeler DF Jr,Yoshioka J

更新日期：1983-03-01 00:00:00

abstract：:Bay U 3405 is a novel thromboxane receptor blocker. The present investigations describe its effects on experimental canine and porcine cardiac damage. In anesthetized dogs, a coronary artery was occluded for 6 hours and reperfused for 30 minutes. Bay U 3405 was administered intravenously 15 minutes after occlusion (1 ...

journal_title：Stroke

authors： Fiedler VB,Seuter F,Perzborn E

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A previous systematic review of randomized trials suggested a positive effect of antiplatelet therapy in patients with aneurysmal subarachnoid hemorrhage (SAH). We performed a randomized controlled trial to assess whether acetylsalicylic acid (ASA) reduces the risk of delayed ischemic neurologica...

journal_title：Stroke

authors： van den Bergh WM,MASH Study Group.,Algra A,Dorhout Mees SM,van Kooten F,Dirven CM,van Gijn J,Vermeulen M,Rinkel GJ

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Dabigatran-etexilate (DE) recently has been approved for stroke prevention in atrial fibrillation. However, lack of effective antagonists represents a major concern in the event of intracerebral hemorrhage (ICH). The aims of the present study were to establish a murine model of ICH associated wit...

journal_title：Stroke

authors： Zhou W,Schwarting S,Illanes S,Liesz A,Middelhoff M,Zorn M,Bendszus M,Heiland S,van Ryn J,Veltkamp R

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The presence of white-matter hyperintensities (WMHs) has been linked to intracerebral hemorrhage (ICH). We sought to determine whether the severity of WMHs influences hematoma growth and ICH volume. METHODS:We retrospectively reviewed prospectively collected clinical, laboratory, and radiologic ...

journal_title：Stroke

authors： Lou M,Al-Hazzani A,Goddeau RP Jr,Novak V,Selim M

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Multiple brain infarcts are often seen on diffusion-weighted images in cardioembolic stroke patients. Recently, mobile aortic plaques (MAPs) have been proposed as embolic sources. However, the clinical characteristics of patients with MAPs are unclear. METHODS:We prospectively studied patients w...

journal_title：Stroke

authors： Ueno Y,Kimura K,Iguchi Y,Shibazaki K,Inoue T,Hattori N,Urabe T

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:5' adenosine monophosphate-dependent protein kinase (AMPK) acts as a metabolic sensor. AMPK is elevated under ischemic conditions, but the role of AMPK in ischemic brain remains controversial. In this study, we examined the effects of AMPK inhibition using both pharmacological and genetic approac...

journal_title：Stroke

authors： Li J,Zeng Z,Viollet B,Ronnett GV,McCullough LD

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The vitamin K-dependent protein Z (PZ) has been shown to possess anticoagulant as well as procoagulant properties. Plasma levels of PZ show a broad interindividual variation, but it is unknown to which extent this variation is under genetic control. Recent clinical studies revealed contradictory ...

journal_title：Stroke

authors： Lichy C,Kropp S,Dong-Si T,Genius J,Dolan T,Hampe T,Stoll F,Reuner K,Grond-Ginsbach C,Grau A

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Elevated cardiac troponin is a marker of cardiac disease and has been recently shown to be associated with embolic stroke risk. We hypothesize that early elevated troponin levels in the acute stroke setting are more prevalent in patients with embolic stroke subtypes (cardioembolic and embolic str...

journal_title：Stroke

authors： Yaghi S,Chang AD,Ricci BA,Jayaraman MV,McTaggart RA,Hemendinger M,Narwal P,Dakay K,Mac Grory B,Cutting SM,Burton TM,Song C,Mehanna E,Siket M,Madsen TE,Reznik M,Merkler AE,Lerario MP,Kamel H,Elkind MSV,Furie KL

更新日期：2018-01-01 00:00:00

abstract：:Using in vivo brain microdialysis, we studied amino acid release in the striatum and cortex of eight rats following permanent middle cerebral artery occlusion. We then processed all brains for histopathologic assessment of the volume of ischemic damage 4 hours after occlusion. Ischemic damage was varied by occlusion o...

journal_title：Stroke

authors： Butcher SP,Bullock R,Graham DI,McCulloch J

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Attained height, an indicator of genetic potential and childhood growth environment, is inversely associated with stroke, but the mechanisms are poorly understood. We investigated whether childhood height and growth are associated with ischemic stroke (IS) and intracerebral hemorrhage (ICH). MET...

journal_title：Stroke

authors： Gjærde LK,Truelsen TC,Baker JL

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Policy makers require evidence on the costs and outcomes of different ways of organizing stroke care. This study compared the costs and survival of different ways of providing stroke care. METHODS:Hospitalized stroke patients from 13 European centers were included, with demographic, case-mix, an...

journal_title：Stroke

authors： Grieve R,Hutton J,Bhalla A,Rastenytë D,Ryglewicz D,Sarti C,Lamassa M,Giroud M,Dundas R,Wolfe CD

更新日期：2001-07-01 00:00:00