abstract：OBJECTIVES:To investigate the utility of 18F-FDG PET/CT in the diagnostic procedure of IgG4-related disease (IgG4-RD), we analysed the association between quantitative method of 18F-FDG PET/CT and histological findings. METHODS:Twenty-one patients with IgG4-RD in whom 18F-FDG PET/CT was performed at the time of diagno...

journal_title：Clinical and experimental rheumatology

authors： Tsuji S,Iwamoto N,Horai Y,Fujikawa K,Fujita Y,Fukui S,Ideguchi R,Michitsuji T,Nishihata S,Okamoto M,Tsuji Y,Endo Y,Shimizu T,Sumiyoshi R,Koga T,Kawashiri SY,Igawa T,Ichinose K,Tamai M,Nakamura H,Origuchi T,Kudo

更新日期：2021-01-28 00:00:00

abstract：OBJECTIVES:To determine biologic disease-modifying anti-rheumatic drug effects on inflammation-induced cardiac geometry and function changes. METHODS:Male and female Sprague-Dawley rats (n=92) were divided into four groups: control group, collagen-induced arthritis (CIA) group, anti-TNF-α group and anti-IL-6 group. In...

journal_title：Clinical and experimental rheumatology

authors： Le Roux R,Mokotedi L,Fourie S,Manilall A,Gunter S,Millen AME

更新日期：2021-01-11 00:00:00

abstract：OBJECTIVES:To evaluate the health-related quality of life (HRQoL), disease activity, treatment adherence, and work ability in the real-world setting in patients with axial spondyloarthritis (axSpA). METHODS:QUASAR was a prospective 12-month, observational study involving 23 rheumatology centres across Italy, including...

journal_title：Clinical and experimental rheumatology

authors： D'Angelo S,Malavolta N,Scambi C,Salvarani C,Caso F,Tirri E,Ramonda R,Quarta L,Erre GL,Riva M,Buono R,Furini F,Grembiale RD,Lomater C,Cantini F,Maio T,Chimenti MS,Scrivo R,Salaffi F,Caporali RF,Volpe P,Gualberti

更新日期：2021-01-06 00:00:00

abstract：OBJECTIVES:To assess the top 5 causes of non-vasculitis hospitalisations in people with vasculitis over time. METHODS:In a national U.S. sample of people with vasculitis hospitalised for reasons other than vasculitis, the rank (and percent) of top 5 causes of hospitalisations and in-hospital mortality were compared in...

journal_title：Clinical and experimental rheumatology

authors： Singh JA

更新日期：2020-12-02 00:00:00

abstract：OBJECTIVES:Fibromyalgia syndrome (FM) is a complex disease that is mainly characterised by chronic widespread pain, fatigue and sleep disturbances and may be precipitated or worsened by many stressors. The aim of this study was to observe the behaviour of FM symptoms during the course of coronavirus disease 2019 (COVID...

journal_title：Clinical and experimental rheumatology

authors： Salaffi F,Giorgi V,Sirotti S,Bongiovanni S,Farah S,Bazzichi L,Marotto D,Atzeni F,Rizzi M,Batticciotto A,Lombardi G,Galli M,Sarzi-Puttini P

更新日期：2020-11-16 00:00:00

abstract：OBJECTIVES:To evaluate the performance of the 2019 European League against Rheumatism/American College of Rheumatology (EULAR/ACR) classification criteria for systemic lupus erythematosus (SLE) in Asian patients. METHODS:We conducted an electronic medical chart review of patients with SLE and defined rheumatic disease...

journal_title：Clinical and experimental rheumatology

authors： Lee EE,Lee EB,Park JK,Lee EY,Song YW

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVES:To compare the occurrence of non-infectious uveitis based on the type of tumour necrosis factor (TNF) inhibitor used to manage spondyloarthritis in ankylosing spondylitis (AS) patients. METHODS:The occurrence (new-onset and recurrence) of uveitis was reviewed retrospectively in AS patients receiving differe...

journal_title：Clinical and experimental rheumatology

authors： Choi EY,Lee M,Lee CS

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVES:To determine prognostic factors for the Health Assessment Questionnaire-Disability Index (HAQ-DI) progression in patients with rheumatoid arthritis (RA) in clinical practice. METHODS:We evaluated 388 biological disease-modifying anti-rheumatic drug (bDMARD)-naïve Japanese patients with RA with moderate to h...

journal_title：Clinical and experimental rheumatology

authors： Sumiyoshi R,Hidaka T,Koga T,Okada A,Fukuda T,Ishii T,Ueki Y,Kodera T,Nakashima M,Takahashi Y,Honda S,Horai Y,Watanabe R,Okuno H,Aramaki T,Izumiyama T,Takai O,Miyashita T,Kawashiri SY,Iwamoto N,Ichinose K,Tamai M

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVES:To investigate whether bone scintigraphy with semiquantitative analysis in patients with early axial spondyloarthritis (axSpA) has prognostic value for predicting spinal structural progression of these patients after 2 years. METHODS:The records of 53 patients with early axSpA who underwent baseline bone sc...

journal_title：Clinical and experimental rheumatology

authors： Min HK,Kim HR,So Y,Chung HW,Lee SH

更新日期：2020-10-09 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is an autoimmune systemic disease characterised by a broad spectrum of clinical manifestations that may also affect the central nervous system. Among the neurological symptoms, seizures were included in the criteria for the classification of SLE published by EULAR/ACR in 2019. Severa...

journal_title：Clinical and experimental rheumatology

authors： Grasso EA,Cacciatore M,Gentile C,Breda L,Giacomelli R,Verrotti A

更新日期：2020-09-04 00:00:00

abstract：OBJECTIVES:Chronic inflammatory arthritis (CIAs), including rheumatoid arthritis (RA), psoriatic arthritis (PsA) and ankylosing spondylitis (AS) are characterised by high cardiovascular disease (CVD) risk, partly due to endothelial dysfunction and increased arterial stiffness of the carotid artery and aorta. The aim of...

journal_title：Clinical and experimental rheumatology

authors： Dalbeni A,Giollo A,Cattazzo F,Bevilacqua M,Mantovani A,Tagetti A,Orsolini G,Cioffi G,Ognibeni F,Minuz P,Rossini M,Viapiana O,Fava C

更新日期：2020-09-03 00:00:00

abstract：OBJECTIVES:Until now, glucocorticoids (GCs) with their anti-inflammatory and immune suppressive effects are one of the most effective agents in therapy of several autoimmune disorders including rheumatoid arthritis (RA). Glucocorticoid receptor (GR) polymorphisms may result in variable sensitivity to glucocorticoids pl...

journal_title：Clinical and experimental rheumatology

authors： Bazsó A,Kövesdi A,Rásonyi R,Nagy E,Poór G,Patócs A,Kiss E

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVES:To compare and analyse the recommendations from clinical practice guidelines (CPGs) on gout worldwide, examine the consistency across CPGs, and provide suggestions to develop and update gout guidelines. METHODS:We conducted systematic searches in MEDLINE, CBM, GIN, NICE, NGC, WHO, SIGN, DynaMed, UpToDate, a...

journal_title：Clinical and experimental rheumatology

authors： Yu Y,Wang D,Zhou Q,Wang C,Ma X,Gao Y,Song X,Xiao S,Wang Q,Zeng X,Estill J,Qian Z,Chen Y

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVES:To provide a detailed description of the ultrasound (US) scanning protocol to measure the muscle thickness in the forearm and to test its feasibility and interobserver reliability. METHODS:Four rheumatologists trained in musculoskeletal US carried out the examinations in 45 subjects (30 consecutively enroll...

journal_title：Clinical and experimental rheumatology

authors： Smerilli G,Castell S,Cipolletta E,Farah S,Carotti M,Salaffi F,Grassi W,Filippucci E

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVES:This systematic literature review (SLR) and network meta-analysis (NMA) was aimed at comparing the relative efficacy and safety of abatacept (ABA) with other currently recommended therapies for patients with early RA. METHODS:An SLR (January 1998 to June 2018) was conducted including MEDLINE®, Embase, and C...

journal_title：Clinical and experimental rheumatology

authors： Paul D,Fazeli MS,Mintzer L,Duarte L,Gupta K,Ferri L

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVES:Defining predictors of damage would improve patient care. We applied damage indexes to patients with familial Mediterranean fever (FMF) and identified the predictors of damage. METHODS:This is a cross-sectional analysis of 926 FMF patients, who fulfilled the Tel-Hashomer criteria and had at least six months...

journal_title：Clinical and experimental rheumatology

authors： Babaoglu H,Armagan B,Bodakci E,Satis H,Atas N,Sari A,Yasar Bilge NS,Bilici Salman R,Yardimci GK,Avanoglu Guler A,Karadeniz H,Kilic L,Ozturk MA,Goker B,Haznedaroglu S,Kalyoncu U,Kasifoglu T,Tufan A

更新日期：2020-09-01 00:00:00

abstract：:Salmonella infections usually present with gastrointestinal manifestations including enterocolitis especially in immunocompromised patients. Haematogenous dissemination and abscesses are very rare complications of Salmonella species. This case report documents a patient with Behçet's syndrome (BS) who has pyomyositis ...

journal_title：Clinical and experimental rheumatology

authors： Kenar G,Köken Avşar A,Balcı A,Can G

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVES:Behçet's disease (BD) is characterised by repeated acute inflammatory attacks with aphthous ulcers of the oral mucosa, uveitis of the eyes, skin symptoms, and genital ulcers. Although its aetiology is still unknown, there is evidence of the involvement of oral bacteria in systemic diseases. Various types of ...

journal_title：Clinical and experimental rheumatology

authors： Balt J,Uehara O,Abiko Y,Jamyanjav B,Jav S,Nagasawa T,Mori M,Horie Y,Fujita M,Lennikov A,Ohta T,Hiraoka M,Iwata D,Namba K,Ohno S,Kitaichi N

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVES:Prediction and determination of drug efficacy for radiographic progression is limited by the heterogeneity inherent in axial spondyloarthritis (axSpA). We investigated whether unbiased clustering analysis of phenotypic data can lead to coherent subgroups of axSpA patients with a distinct risk of radiographic...

journal_title：Clinical and experimental rheumatology

authors： Joo YB,Baek IW,Park KS,Tagkopoulos I,Kim KJ

更新日期：2020-07-10 00:00:00

abstract：OBJECTIVES:Lupus nephritis (LN) is an immune-complex mediated nephritis with complicated pathogenesis. The aims of the present study were to investigate whether inflammasomes are activated in the renal pathology of LN patients and analyse the association of inflammasome activation in different classes of LN renal tissu...

journal_title：Clinical and experimental rheumatology

authors： Huang T,Yin H,Ning W,Wang X,Chen C,Lin W,Li J,Zhou Y,Peng Y,Wang M,Ni X,Zhang W

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVES:Rheumatoid arthritis (RA) is a systematic autoimmune disease that cardinally affects the joints and other organs. Many people all over the world are suffering from the disease and no effective treatment has been established. Fibroblast-like synoviocytes (FLSs) play a critical role in the occurrence and devel...

journal_title：Clinical and experimental rheumatology

authors： Yu H,Ding C,Dai S,Sun J,Wang S,Zhang Z

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVES:Systemic lupus erythematosus (SLE) is a chronic autoimmune multi-organ disease with an unpredictable course. SLE causes functional disability, changes in body appearance, and psychological distress. When faced with SLE, patients have to implement coping strategies. Therefore, the aim of this study was to des...

journal_title：Clinical and experimental rheumatology

authors： Farhat MM,Morell-Dubois S,Le Gouellec N,Launay D,Maillard H,Balquet MH,Azar R,Quemeneur T,Boldron A,Bataille P,Lambert M,Lanteri A,Buchdahl AL,Sobanski V,Hatron PY,Hachulla E,Clerson P,ESSTIM Investigators group.

更新日期：2020-07-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a relapsing-remitting course that can affect various organs or systems, leading to a broad spectrum of clinical manifestations. In the past year, many studies have been published on SLE, providing a significant advancement in disease knowledge and...

journal_title：Clinical and experimental rheumatology

authors： Signorini V,Elefante E,Zucchi D,Trentin F,Bortoluzzi A,Tani C

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVES:The presence and severity of focal lymphocytic sialadenitis in minor salivary glands is a pathognomonic feature in primary Sjögren's syndrome (pSS). However, it has not been determined whether performing minor salivary gland biopsy (MSGB) in a setting of serologically and clinically established pSS provides ...

journal_title：Clinical and experimental rheumatology

authors： Park Y,Lee J,Koh JH,Choe JY,Sung YK,Lee SS,Shim SC,Kim JM,Kwon SR,Park SH,Kwok SK

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVES:To identify the role of nailfold capillaroscopy (NC) in Sjögren's syndrome (SS). METHODS:The literature was systematically reviewed in three databases. All published original studies which assess patients with SS by NC were revised. A quality assessment was applied to all studies based on population descrip...

journal_title：Clinical and experimental rheumatology

authors： Melsens K,Leone MC,Paolino S,Elewaut D,Gerli R,Vanhaecke A,Peene I,Cutolo M,Smith V

更新日期：2020-07-01 00:00:00

abstract：:Primary Sjögren's syndrome (pSS) is often considered a B cell-mediated disease, yet the precise role of B cells in the pathogenesis is not fully understood. This is exemplified by the failure of multiple clinical trials directed at B cell depletion or inhibition. To date, most prognostic markers for severe disease out...

journal_title：Clinical and experimental rheumatology

authors： Reed JH,Verstappen GM,Rischmueller M,Bryant VL

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVES:Digestive involvement (DI) has been reported in 10-30% of primary Sjögren's syndrome (pSS) patients, and few studies have systematically analysed the prevalence of DI in pSS patients. The aim of this study was to describe DI prevalence in pSS patients from the Sjögrenser Study, and to analyse its clinical as...

journal_title：Clinical and experimental rheumatology

authors： Melchor S,Sánchez-Piedra C,Fernández Castro M,Andreu JL,Martínez Taboada V,Olivé A,Rosas J,Menor R,García-Aparicio Á,López Longo FJ,Manrique-Arija S,García Vadillo JA,López González R,Narváez J,Galisteo C,González Martín J

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVES:Assess if kynurenines metabolites are biomarkers of damage at labial salivary gland biopsy (LSGB). METHODS:This is a cross-sectional study including 99 patients with primary Sjögren's syndrome (AECG 2002 or ACR/EULAR 2017). Kynurenines were measured in plasma using liquid chromatography-tandem mass spectrom...

journal_title：Clinical and experimental rheumatology

authors： Sardenberg WM,Santos MCLFS,Skarstein K,Carvalho Caser L,Brun JG,Ulvik A,Ueland PM,Mydel PM,Jonsson R,Valim V

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVES:Non-genetic risk factors for Sjögren's syndrome (SS) are poorly understood. Adherence to a Mediterranean diet has been associated with reduction in other autoimmune diseases. We examined the association of Mediterranean diet with SS. METHODS:New patients attending a single centre warranting investigation fo...

journal_title：Clinical and experimental rheumatology

authors： Machowicz A,Hall I,de Pablo P,Rauz S,Richards A,Higham J,Poveda-Gallego A,Imamura F,Bowman SJ,Barone F,Fisher BA

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVES:Primary Sjögren's syndrome (pSS) is one of the most prevalent systemic autoimmune diseases characterised by inflammation and tissue damage of exocrine glands, especially salivary or lacrimal gland. IL-17 related immune response is pathogenic with proinflammatory feature in pSS. However, whether IL-17E, an IL...

journal_title：Clinical and experimental rheumatology

authors： Zhao X,Gan Y,Jin Y,He J,Jia R,Li Y,Luan H,Ye H,Wang Q,Liu Y,Shen D,Sun X,Li Z

更新日期：2020-06-12 00:00:00

abstract：OBJECTIVES:The interface between pro-inflammatory cytokines and rheumatoid synovial fibroblast (sFLS) has central effects on rheumatoid arthritis (RA). The present study aimed to explore the role of IL-34 expression as one of major cytokine implicated in RA. METHODS:We examined the expression of IL-34 after RA sFLS st...

journal_title：Clinical and experimental rheumatology

authors： Elkhider A,Wei J,Al-Azab M,Tang Y,Walana W,Li W,Yuan B,Ye Y,Wang G,Zhang Y,Li X

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVES:We evaluated age at natural menopause and the prevalence of premature ovarian failure (POF) in a monocentric Caucasian cohort of patients with systemic lupus erythematosus (SLE). METHODS:In this cross-sectional study, we enrolled women affected by SLE compared with healthy controls (HC) to investigate data ...

journal_title：Clinical and experimental rheumatology

authors： Ceccarelli F,Orefice V,Perrone G,Pirone C,Perricone C,Truglia S,Miranda F,Pacucci VA,Spinelli FR,Galoppi P,Alessandri C,Valesini G,Conti F

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVES:Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a serine protease that regulates cholesterol metabolism through low-density lipoprotein receptor degradation, and which has been linked to cardiovascular risk. The purpose of the present study was to examine whether PCSK9 serum levels are disrupted in ...

journal_title：Clinical and experimental rheumatology

authors： Ferraz-Amaro I,Delgado-Frías E,Hernández-Hernández V,Sánchez-Pérez H,de Armas-Rillo L,García-Dopico JA,Díaz-González F

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to evaluate homocysteine (Hcy) serum levels in women with systemic sclerosis (SSc) compared with healthy controls and to examine possible associations between Hcy and markers of arterial stiffness. METHODS:A cross-sectional study was performed at a single hospital between Novem...

journal_title：Clinical and experimental rheumatology

authors： Álvarez-Cienfuegos A,Cantero-Nieto L,García-Gómez JA,Sabio JM,González-Gay MA,Ortego-Centeno N

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVES:To assess the educational needs of people with ankylosing spondylitis (AS) and psoriatic arthritis (PsA), test differences across patient subgroups and identify factors independently associated with their educational needs. METHODS:This was a cross-sectional analytic study. Patients with AS and PsA complete...

journal_title：Clinical and experimental rheumatology

authors： Marques ML,Ferreira RJO,Machado PM,Marques A,da Silva JAP,Ndosi M

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVES:Neurosarcoidosis (NS) and primary angiitis of central nervous system (PACNS) are inflammatory diseases affecting central nervous system, with overlapping clinical and pathological characteristics. Distinguishing these diseases is important given distinct therapeutic implications. In this study, we aimed to c...

journal_title：Clinical and experimental rheumatology

authors： Saygin D,Jones S,Sundaram P,Calabrese LH,Messner W,Tavee JO,Hajj-Ali RA

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVES:Essential mixed cryoglobulinaemia (EMC) is a disorder of B-cells producing rheumatoid factor (RF), and is clinically and immunologically similar to mixed cryoglobulinaemia (MC) related to hepatitis C virus (HCV-MC). We report here the first comprehensive analysis of B-cell clonality, phenotype and function i...

journal_title：Clinical and experimental rheumatology

authors： Del Padre M,Minafò YA,Marrapodi R,Radicchio G,Granata M,Camponeschi A,Fiorilli M,Quartuccio L,De Vita S,Casato M,Colantuono S,Visentini M

更新日期：2020-03-01 00:00:00

abstract：:A severe outbreak of coronavirus disease 2019 (COVID-19) emerged in China in December 2019, and spread so rapidly that more than 200,000 cases have so far been reported worldwide; on January 30, 2020, the WHO declared it the sixth public health emergency of international concern. The two previously reported coronaviru...

journal_title：Clinical and experimental rheumatology

authors： Sarzi-Puttini P,Giorgi V,Sirotti S,Marotto D,Ardizzone S,Rizzardini G,Antinori S,Galli M

更新日期：2020-03-01 00:00:00

abstract：:Giant cell arteritis (GCA), a systemic large-vessel vasculitis, is a disease that has been treated with glucocorticoids since 1950. Over the years, several disease-modifying anti-rheumatic drugs have been evaluated as steroid-sparing agents with disappointing results. Tocilizumab, an interleukin-6 inhibitor, has in re...

journal_title：Clinical and experimental rheumatology

authors： Naderi N

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVES:Literature shows high rates of comorbidity between fibromyalgia (FM) and mood disorders, especially major depressive disorder (MMD), reported in more than half of the cases. Consistently, patients with FM also present high rates of mood spectrum symptoms, despite scant data are still available on the relatio...

journal_title：Clinical and experimental rheumatology

authors： Carmassi C,Ciapparelli A,Cappelli A,Dell'Oste V,Bertelloni CA,Foghi C,Amatori G,Pedrinelli V,Bazzichi L,Dell'Osso L

更新日期：2020-02-26 00:00:00