听力与言语-语言病理学

行为科学

医学伦理学

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  • The broad autism phenotype in real-life: clinical and functional correlates of autism spectrum symptoms and rumination among parents of patients with autism spectrum disorder.

    abstract:OBJECTIVE:Increasing literature reported higher rates of psychiatric disorders in parents of children with autism spectrum disorder (ASD), as well as of autistic-like features in social and cognitive functioning. However, little attention has been paid to the association between autistic traits (AT) and global function...

    journal_title:CNS spectrums

    pub_type: 杂志文章

    doi:10.1017/S1092852919001615

    authors: Carpita B,Carmassi C,Calderoni S,Muti D,Muscarella A,Massimetti G,Cremone IM,Gesi C,Conti E,Muratori F,Dell'Osso L

    更新日期:2020-12-01 00:00:00

  • From trauma-blind to trauma-informed: re-thinking criminalization and the role of trauma in persons with serious mental illness.

    abstract::Trauma-informed approaches offer a new perspective for understanding how and why individuals with serious mental illness (SMI) become entangled in the criminal justice system. There is growing awareness that many individuals with SMI have experienced significant life trauma, and factors beyond SMI that contribute to c...

    journal_title:CNS spectrums

    pub_type: 杂志文章

    doi:10.1017/S1092852920001169

    authors: Thordarson H,Rector T

    更新日期:2020-10-01 00:00:00

  • Fixated Threat Assessment Centers: preventing harm and facilitating care in public figure threat cases and those thought to be at risk of lone-actor grievance-fueled violence.

    abstract::The rediscovery of the importance of mental illness in the risk assessment and management of those who threaten, approach, and harm public figures has led to a new way of dealing with those that threaten public figures. This approach emphasises the role of "fixation" which may be defined as an intense preoccupation pu...

    journal_title:CNS spectrums

    pub_type: 杂志文章

    doi:10.1017/S1092852920000152

    authors: Barry-Walsh J,James DV,Mullen PE

    更新日期:2020-10-01 00:00:00

  • Sexual response in obsessive-compulsive disorder: the role of obsessive beliefs.

    abstract:BACKGROUND.:Sexual response in obsessive-compulsive disorder (OCD) research and practice is overlooked. According to the Dual Control Model, satisfactory sexual response is based upon a balance of sexual excitation and inhibition. The assessment of sexual response in OCD may have clinical implications, such as the inte...

    journal_title:CNS spectrums

    pub_type: 杂志文章

    doi:10.1017/S1092852920001649

    authors: Pozza A,Marazziti D,Mucci F,Angelo NL,Prestia D,Dèttore D

    更新日期:2020-07-15 00:00:00

  • Suicidal ideation and behavior in adults with major depressive disorder treated with vortioxetine: post hoc pooled analyses of randomized, placebo-controlled, short-term and open-label, long-term extension trials.

    abstract:OBJECTIVES:This study aimed to evaluate the risk of suicidal ideation and behavior associated with vortioxetine treatment in adults with major depressive disorder (MDD). METHODS:Suicide-related events were evaluated post hoc using 2 study pools: one short-term pool of 10 randomized, placebo-controlled studies (6-8 wee...

    journal_title:CNS spectrums

    pub_type: 杂志文章

    doi:10.1017/S109285291900097X

    authors: Mahableshwarkar AR,Affinito J,Reines EH,Xu J,Nomikos G,Jacobsen PL

    更新日期:2020-06-01 00:00:00

  • Cold pressor pain and gambling disorder: implications for the opioid system.

    abstract:OBJECTIVE:Gambling disorder (GD) is a common, disabling condition that often is exacerbated by stressful life events. Under stress, the sympathetic nervous system and the hypothalamic-pituitary-adrenal axis are activated. The question, therefore, arises as to whether an abnormal sympathetic response can be found in ind...

    journal_title:CNS spectrums

    pub_type: 杂志文章

    doi:10.1017/S109285291900107X

    authors: Grant JE,Chamberlain SR

    更新日期:2020-06-01 00:00:00

  • Outcome in depression (I): why symptomatic remission is not good enough.

    abstract:BACKGROUND.:The Leuven Affect and Pleasure Scale (LAPS) is a depression outcome measure aiming to better reflect patient treatment expectations. We investigated the evolution of the LAPS and some comparator scales during antidepressant treatment and compared scores of remitters with scores of healthy controls.Methods. ...

    journal_title:CNS spectrums

    pub_type: 杂志文章

    doi:10.1017/S1092852920001418

    authors: Demyttenaere K,Kiekens G,Bruffaerts R,Mortier P,Gorwood P,Martin L,Di Giannantonio M

    更新日期:2020-05-19 00:00:00

  • Suicidality and self-injurious behavior among adolescent social media users at psychiatric hospitalization.

    abstract:BACKGROUND.:The current study sought to examine the relationship between documented social media use and suicidality and self-injurious behaviors in adolescents at the time of psychiatric hospitalization. METHODS.:We retrospectively identified adolescents (aged 12-17 years) hospitalized on an inpatient psychiatric uni...

    journal_title:CNS spectrums

    pub_type: 杂志文章

    doi:10.1017/S1092852920001108

    authors: Shafi RMA,Nakonezny PA,Romanowicz M,Nandakumar AL,Suarez L,Croarkin PE

    更新日期:2020-04-27 00:00:00

  • Urbanization and emerging mental health issues.

    abstract::Rapid urbanization worldwide is associated to an increase of population in the urban settings and this is leading to new emerging mental health issues. This narrative mini-review is based on a literature search conducted through PubMed and EMBASE. A total of 113 articles published on the issue of urban mental health h...

    journal_title:CNS spectrums

    pub_type: 杂志文章

    doi:10.1017/S1092852920001236

    authors: Ventriglio A,Torales J,Castaldelli-Maia JM,De Berardis D,Bhugra D

    更新日期:2020-04-06 00:00:00

  • Competence to stand trial and criminalization: an overview of the research.

    abstract::Beginning in the 1960s, a steady decline in the number of inpatient psychiatric beds has occurred across the United States, primarily as a result of stricter civil commitment criteria and a societal movement toward deinstitutionalization. Concomitant with this decrease in psychiatric beds has been a steady increase in...

    journal_title:CNS spectrums

    pub_type: 杂志文章

    doi:10.1017/S1092852919001597

    authors: Beltrani A,Zapf PA

    更新日期:2020-04-01 00:00:00

  • The increasing challenge of the possible impact of ethnicity on psychopharmacology.

    abstract::Ethnic differences may significantly influence the outcome of psychopharmacological treatment, in terms of prescription, adherence, clinical response, emergence of side effects, as well as pharmacokinetics and pharmacodynamics. The purpose of this review was to explore the available literature in order to provide gene...

    journal_title:CNS spectrums

    pub_type: 杂志文章

    doi:10.1017/S1092852920000073

    authors: Marazziti D,Mucci F,Avella MT,Palagini L,Simoncini M,Dell'Osso L

    更新日期:2020-03-02 00:00:00

  • The effect of caloric restriction on working memory in healthy non-obese adults.

    abstract:OBJECTIVE:We aim to evaluate the effect of caloric restriction (CR) in cognition by comparing performance in neuropsychological tests for working memory between a group of non-obese healthy subjects doing CR for 2 years with another consuming ad libitum diet (AL). METHODS:This study was part of a larger multicenter tr...

    journal_title:CNS spectrums

    pub_type: 杂志文章

    doi:10.1017/S1092852918001566

    authors: Leclerc E,Trevizol AP,Grigolon RB,Subramaniapillai M,McIntyre RS,Brietzke E,Mansur RB

    更新日期:2020-02-01 00:00:00

  • Analysis of the superior temporal gyrus as a possible biomarker in schizophrenia using voxel-based morphometry of the brain magnetic resonance imaging: a comprehensive review.

    abstract::The lack of predictive biomarkers for therapeutic responses to schizophrenia leads clinical procedures to be decided without taking into account the subjects' neuroanatomical features, a consideration, which could help in identifying specific pharmacological treatments for the remission of symptoms. Magnetic resonance...

    journal_title:CNS spectrums

    pub_type: 杂志文章

    doi:10.1017/S1092852919001810

    authors: Bandeira ID,Barouh JL,Bandeira ID,Quarantini L

    更新日期:2020-01-10 00:00:00

  • FDA-approved drugs for multiple sclerosis have no efficacy or disability data in non-Caucasian patients.

    abstract::Pharmacotherapy of multiple sclerosis (MS) is evolving rapidly. Despite impressive gains over the past 2 decades in the approval of multiple drugs for MS, lack of recruitment of minorities with MS in phase 3 clinical studies is a persistent concern and skews efficacy and disability data. ...

    journal_title:CNS spectrums

    pub_type: 社论

    doi:10.1017/S1092852918001517

    authors: Avasarala J

    更新日期:2019-06-01 00:00:00

  • Is there enough "interest in and pleasure in" the concept of depression? The development of the Leuven Affect and Pleasure Scale (LAPS).

    abstract:OBJECTIVE:Presence of negative mood (depressed mood) and anhedonia (lack of interest and pleasure) are considered core symptoms of depression, while absence of positive mood is not taken into account. It is therefore remarkable that the depression scales routinely used to assess changes during antidepressant treatment ...

    journal_title:CNS spectrums

    pub_type: 杂志文章

    doi:10.1017/S1092852917000578

    authors: Demyttenaere K,Mortier P,Kiekens G,Bruffaerts R

    更新日期:2019-04-01 00:00:00

  • Neurodegeneration of brain networks in the amyotrophic lateral sclerosis-frontotemporal lobar degeneration (ALS-FTLD) continuum: evidence from MRI and MEG studies.

    abstract::Brain imaging techniques, especially those based on magnetic resonance imaging (MRI) and magnetoencephalography (MEG), have been increasingly applied to study multiple large-scale distributed brain networks in healthy people and neurological patients. With regard to neurodegenerative disorders, amyotrophic lateral scl...

    journal_title:CNS spectrums

    pub_type: 杂志文章,评审

    doi:10.1017/S109285291700075X

    authors: Trojsi F,Sorrentino P,Sorrentino G,Tedeschi G

    更新日期:2018-12-01 00:00:00

  • Comparing pharmacologic mechanism of action for the vesicular monoamine transporter 2 (VMAT2) inhibitors valbenazine and deutetrabenazine in treating tardive dyskinesia: does one have advantages over the other?

    abstract::The two approved treatments for tardive dyskinesia both inhibit the vesicular monoamine transporter type 2 (VMAT2) yet have pharmacologic properties that distinguish one from the other. Knowing these differences may help optimize which treatment to select for individual patients. ...

    journal_title:CNS spectrums

    pub_type: 杂志文章,评审

    doi:10.1017/S1092852918001219

    authors: Stahl SM

    更新日期:2018-08-01 00:00:00

  • The following abstracts were presented as posters at the 2017 NEI Congress.

    abstract::Congratulations to the scientific poster winners: 1 st Place: #178-Gender Differences in Prodromal Symptoms of Dementia 2 nd Place: #146-Effect of Heroin Use on Changes of Brain Functions As Measured by fMRI, a Systematic Review 3 rd Place: #185-Second Generation Antipsychotics and Catatonia: A Literature Review. ...

    journal_title:CNS spectrums

    pub_type: 杂志文章

    doi:10.1017/S1092852918000044

    authors:

    更新日期:2018-02-01 00:00:00

  • Drugs for psychosis and mood: unique actions at D3, D2, and D1 dopamine receptor subtypes.

    abstract::Drugs for psychosis and mood that bind dopamine D2 receptors can be classified not only by whether they also block serotonin 2A receptors, but by whether they also bind D3 or D1 receptors. ...

    journal_title:CNS spectrums

    pub_type: 杂志文章,评审

    doi:10.1017/S1092852917000608

    authors: Stahl SM

    更新日期:2017-10-01 00:00:00

  • Asenapine for the treatment of adults with an acute exacerbation of schizophrenia: results from a randomized, double-blind, fixed-dose, placebo-controlled trial with olanzapine as an active control.

    abstract:OBJECTIVE:Evaluate the efficacy and safety of asenapine 2.5 mg twice daily (bid; n=97) or 5 mg bid (n=113) versus placebo (n=101) in adults with acute exacerbation of schizophrenia. METHODS:Adults with Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR) schizophrenia diagno...

    journal_title:CNS spectrums

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1017/S1092852916000377

    authors: Landbloom R,Mackle M,Wu X,Kelly L,Snow-Adami L,McIntyre RS,Mathews M,Hundt C

    更新日期:2017-08-01 00:00:00

  • Deep brain stimulation for bipolar disorder-review and outlook.

    abstract::Research on deep brain stimulation (DBS) for treatment-resistant psychiatric disorders has established preliminary efficacy signals for treatment-resistant depression. There are only few studies on DBS that included patients suffering from bipolar disorder. This article gives an overview of these studies concerning DB...

    journal_title:CNS spectrums

    pub_type: 杂志文章,评审

    doi:10.1017/S1092852915000577

    authors: Gippert SM,Switala C,Bewernick BH,Kayser S,Bräuer A,Coenen VA,Schlaepfer TE

    更新日期:2017-06-01 00:00:00

  • Guidelines for the recognition and management of mixed depression.

    abstract::A significant minority of people presenting with a major depressive episode (MDE) experience co-occurring subsyndromal hypo/manic symptoms. As this presentation may have important prognostic and treatment implications, the DSM-5 codified a new nosological entity, the "mixed features specifier," referring to individual...

    journal_title:CNS spectrums

    pub_type: 杂志文章,评审

    doi:10.1017/S1092852917000165

    authors: Stahl SM,Morrissette DA,Faedda G,Fava M,Goldberg JF,Keck PE,Lee Y,Malhi G,Marangoni C,McElroy SL,Ostacher M,Rosenblat JD,Solé E,Suppes T,Takeshima M,Thase ME,Vieta E,Young A,Zimmerman M,McIntyre RS

    更新日期:2017-04-01 00:00:00

  • Measures of the DSM-5 mixed-features specifier of major depressive disorder.

    abstract::During the past two decades, a number of studies have found that depressed patients frequently have manic symptoms intermixed with depressive symptoms. While the frequency of mixed syndromes are more common in bipolar than in unipolar depressives, mixed states are also common in patients with major depressive disorder...

    journal_title:CNS spectrums

    pub_type: 杂志文章

    doi:10.1017/S1092852916000857

    authors: Zimmerman M

    更新日期:2017-04-01 00:00:00

  • Mixed features in bipolar disorder.

    abstract::Mixed affective states, defined as the coexistence of depressive and manic symptoms, are complex presentations of manic-depressive illness that represent a challenge for clinicians at the levels of diagnosis, classification, and pharmacological treatment. The evidence shows that patients with bipolar disorder who have...

    journal_title:CNS spectrums

    pub_type: 杂志文章

    doi:10.1017/S1092852916000869

    authors: Solé E,Garriga M,Valentí M,Vieta E

    更新日期:2017-04-01 00:00:00

  • Clinical management of restless legs syndrome in end-stage renal disease patients.

    abstract::Restless legs syndrome (RLS) is a common neurological movement disorder, characterized by restless and unpleasant sensations in the deep inside of legs. The symptoms of RLS are less noticeable during daytime, but more prevalent at night. Therefore, the disorder can induce low quality of life, insomnia, and impairment ...

    journal_title:CNS spectrums

    pub_type: 杂志文章,评审

    doi:10.1017/S109285291600064X

    authors: Sahli ZT,Jo J,Mousa SA,Tarazi FI

    更新日期:2017-02-01 00:00:00

  • Obsessive compulsive and related disorders: comparing DSM-5 and ICD-11.

    abstract::Obsessive-compulsive disorder (OCD) has been recognized as mainly characterized by compulsivity rather than anxiety and, therefore, was removed from the anxiety disorders chapter and given its own in both the American Psychiatric Association (APA) Diagnostic and Statistical Manual of Mental Disorders (DSM-5) and the B...

    journal_title:CNS spectrums

    pub_type: 杂志文章,评审

    doi:10.1017/S1092852916000110

    authors: Marras A,Fineberg N,Pallanti S

    更新日期:2016-08-01 00:00:00

  • Mechanism of action of pimavanserin in Parkinson's disease psychosis: targeting serotonin 5HT2A and 5HT2C receptors.

    abstract::Pimavanserin, a novel agent approved for the treatment of Parkinson's disease psychosis, has potent actions as an antagonist/inverse agonist at serotonin 5HT2A receptors and less potent antagonist/inverse agonist actions at 5HT2C receptors. ...

    journal_title:CNS spectrums

    pub_type: 杂志文章

    doi:10.1017/S1092852916000407

    authors: Stahl SM

    更新日期:2016-08-01 00:00:00

  • Nonepileptic seizures: an updated review.

    abstract::Psychogenic nonepileptic seizures (PNES) are a functional neurological disorder/conversion disorder subtype, which are neurobehavioral conditions at the interface of neurology and psychiatry. Significant advancements over the past decade have been made in the diagnosis, management, and neurobiological understanding of...

    journal_title:CNS spectrums

    pub_type: 杂志文章,评审

    doi:10.1017/S109285291600002X

    authors: Perez DL,LaFrance WC Jr

    更新日期:2016-06-01 00:00:00

  • The intentional brain--a short history of neuropsychiatry.

    abstract::Neuropsychiatry has had different meanings at different times in the history of clinical neuroscience. In this article, the origins of what has become today's neuropsychiatry are briefly explored, hopefully revealing a number of pioneers of the discipline, some of the names being familiar to many readers, others howev...

    journal_title:CNS spectrums

    pub_type: 历史文章,杂志文章,评审

    doi:10.1017/S1092852916000195

    authors: Trimble M

    更新日期:2016-06-01 00:00:00

  • Relationship between olfactory function and social cognition in euthymic bipolar patients.

    abstract:OBJECTIVE/INTRODUCTION:There is a close functional and neuroanatomical relationship between olfactory ability and emotional processing. The present study seeks to explore the association between olfactory ability and social cognition, especially facial emotion perception, in euthymic bipolar patients. METHODS:Thirty-n...

    journal_title:CNS spectrums

    pub_type: 杂志文章

    doi:10.1017/S1092852913000382

    authors: Lahera G,Ruiz-Murugarren S,Fernández-Liria A,Saiz-Ruiz J,Buck BE,Penn DL

    更新日期:2016-02-01 00:00:00

  • Cognitive biases in binge eating disorder: the hijacking of decision making.

    abstract::Binge eating disorder (BED) is the most common of eating disorders and is characterized by excessive, out-of-control, rapid food intake. This review focuses on cognitive impairments in BED, which represent an endophenotype that mediates brain function and behavior. Here we focus on reviewing impulsivity, compulsivity,...

    journal_title:CNS spectrums

    pub_type: 杂志文章,评审

    doi:10.1017/S1092852915000681

    authors: Voon V

    更新日期:2015-12-01 00:00:00

  • The epidemiology and genetics of binge eating disorder (BED).

    abstract::This narrative review provides an overview of the epidemiology of binge eating disorder (BED), highlighting the medical history of this disorder and its entry as an independent condition in the Feeding and Eating Disorders section of the recently published Diagnostic and Statistical Manual of Mental Disorders, Fifth E...

    journal_title:CNS spectrums

    pub_type: 杂志文章,评审

    doi:10.1017/S1092852915000462

    authors: Davis C

    更新日期:2015-12-01 00:00:00

  • Continuous performance test in pediatric obsessive-compulsive disorder and tic disorders: the role of sustained attention.

    abstract:OBJECTIVE:Pediatric obsessive-compulsive disorder (OCD) and tic disorders (TD) are often associated with attention-deficit hyperactivity disorder (ADHD). In order to clarify the role of attention and inhibitory control in pediatric OCD and TD, a continuous performance test (CPT) was administered to a cohort of children...

    journal_title:CNS spectrums

    pub_type: 杂志文章

    doi:10.1017/S1092852914000467

    authors: Lucke IM,Lin C,Conteh F,Federline A,Sung H,Specht M,Grados MA

    更新日期:2015-10-01 00:00:00

  • Modes and nodes explain the mechanism of action of vortioxetine, a multimodal agent (MMA): modifying serotonin's downstream effects on glutamate and GABA (gamma amino butyric acid) release.

    abstract::Vortioxetine is an antidepressant with multiple pharmacologic modes of action at targets where serotonin neurons connect with other neurons. These actions modify the release of both glutamate and GABA (gamma amino butyric acid) within various brain circuits. ...

    journal_title:CNS spectrums

    pub_type: 杂志文章,评审

    doi:10.1017/S1092852915000334

    authors: Stahl SM

    更新日期:2015-08-01 00:00:00

  • Forensic focused treatment planning: a new standard for forensic mental health systems.

    abstract::Almost no literature addresses treatment planning for the forensic psychiatric patient. In the absence of such guidance, recovery-oriented multifocal treatment planning has been imported into forensic mental health systems from community psychiatric settings, despite the fact that conditions of admission and discharge...

    journal_title:CNS spectrums

    pub_type: 杂志文章,评审

    doi:10.1017/S1092852915000152

    authors: Schaufenbil RJ,Kornbluh R,Stahl SM,Warburton KD

    更新日期:2015-06-01 00:00:00

  • Behavioral addictions: a novel challenge for psychopharmacology.

    abstract::Although addictive syndromes have been traditionally related to substance-use disorders, during the last few decades a novel addictive group, including the so-called "behavioral or no-drug addictions," has been recognized and has attracted increasing attention for its relevant social impact. This group includes pathol...

    journal_title:CNS spectrums

    pub_type: 杂志文章,评审

    doi:10.1017/S1092852913001041

    authors: Marazziti D,Presta S,Baroni S,Silvestri S,Dell'Osso L

    更新日期:2014-12-01 00:00:00

  • Efficacy of adjunctive aripiprazole in patients with major depressive disorder whose symptoms worsened with antidepressant monotherapy.

    abstract:INTRODUCTION:Efficacy of depression treatments, including adjunctive antipsychotic treatment, has not been explored for patients with worsening symptoms after antidepressant therapy (ADT). METHODS:This post-hoc analysis utilized pooled data from 3 similarly designed, randomized, double-blind, placebo-controlled trials...

    journal_title:CNS spectrums

    pub_type: 杂志文章

    doi:10.1017/S109285291300103X

    authors: Nelson JC,Rahman Z,Laubmeier KK,Eudicone JM,McQuade RD,Berman RM,Marcus RN,Baker RA,Sheehan JJ

    更新日期:2014-12-01 00:00:00

  • Mechanism of action of tasimelteon in non-24 sleep-wake syndrome: treatment for a circadian rhythm disorder in blind patients.

    abstract:ISSUE:Many individuals with total blindness can develop a circadian rhythm disorder-called non-24 sleep wake syndrome-because they cannot detect light to resynchronize their sleep-wake cycles. A new melatonin 1 and melatonin 2 agonist tasimelteon improves sleep in these patients, resetting their circadian sleep-wake cl...

    journal_title:CNS spectrums

    pub_type: 杂志文章,评审

    doi:10.1017/S1092852914000637

    authors: Stahl SM

    更新日期:2014-12-01 00:00:00

  • Add-on clinical effects of selective antagonist of 5HT6 receptors AVN-211 (CD-008-0173) in patients with schizophrenia stabilized on antipsychotic treatment: pilot study.

    abstract:UNLABELLED:The serotoninergic system as a target for add-on treatment seems to be a promising approach in patients with schizophrenia. OBJECTIVE:To clarify if selective 5HT-6 antagonist AVN-211 (CD-008-0173) adds clinical and cognitive effects to stable antipsychotic treatment. METHODS:A randomized, double-blind, pla...

    journal_title:CNS spectrums

    pub_type: 杂志文章,随机对照试验

    doi:10.1017/S1092852913000394

    authors: Morozova MA,Lepilkina TA,Rupchev GE,Beniashvily AG,Burminskiy DS,Potanin SS,Bondarenko EV,Kazey VI,Lavrovsky Y,Ivachtchenko AV

    更新日期:2014-08-01 00:00:00

  • Daytime sleepiness associated with lurasidone and quetiapine XR: results from a randomized double-blind, placebo-controlled trial in patients with schizophrenia.

    abstract:OBJECTIVE:The aim of this analysis was to compare the effects of 2 atypical antipsychotic agents, lurasidone (80 mg/d or 160 mg/d) and quetiapine XR (600 mg/d), on daytime alertness, and to evaluate the effects of daytime sleepiness on treatment outcomes in patients with an acute exacerbation of schizophrenia. METHODS...

    journal_title:CNS spectrums

    pub_type: 杂志文章,随机对照试验

    doi:10.1017/S1092852913000904

    authors: Loebel AD,Siu CO,Cucchiaro JB,Pikalov AA,Harvey PD

    更新日期:2014-04-01 00:00:00

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