听力与言语-语言病理学

行为科学

医学伦理学

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  • To be or not to be: endothelial cell plasticity in development, repair, and disease.

    abstract::Endothelial cells display an extraordinary plasticity both during development and throughout adult life. During early development, endothelial cells assume arterial, venous, or lymphatic identity, while selected endothelial cells undergo additional fate changes to become hematopoietic progenitor, cardiac valve, and ot...

    journal_title:Angiogenesis

    pub_type: 杂志文章,评审

    doi:10.1007/s10456-020-09761-7

    authors: Greenspan LJ,Weinstein BM

    更新日期:2021-01-15 00:00:00

  • Are antiangiogenics a good 'partner' for immunotherapy in ovarian cancer?

    abstract::Ovarian cancer (OC) is associated with poor survival because there are a limited number of effective therapies. Two processes key to OC progression, angiogenesis and immune evasion, act synergistically to promote tumor progression. Tumor-associated angiogenesis promotes immune evasion, and tumor-related immune respons...

    journal_title:Angiogenesis

    pub_type: 杂志文章,评审

    doi:10.1007/s10456-020-09734-w

    authors: García-Martínez E,Redondo A,Piulats JM,Rodríguez A,Casado A

    更新日期:2020-11-01 00:00:00

  • Arterial endoglin does not protect against arteriovenous malformations.

    abstract:INTRODUCTION:Endoglin (ENG) forms a receptor complex with ALK1 in endothelial cells (ECs) to promote BMP9/10 signalling. Loss of function mutations in either ENG or ALK1 genes lead to the inherited vascular disorder hereditary haemorrhagic telangiectasia (HHT), characterised by arteriovenous malformations (AVMs). Howev...

    journal_title:Angiogenesis

    pub_type: 杂志文章

    doi:10.1007/s10456-020-09731-z

    authors: Singh E,Redgrave RE,Phillips HM,Arthur HM

    更新日期:2020-11-01 00:00:00

  • Piwi-interacting RNAs (piRNAs) as potential biomarkers and therapeutic targets for cardiovascular diseases.

    abstract::Cardiovascular diseases (CVDs) are the leading causes of death worldwide. Increasing reports demonstrated that non-coding RNAs (ncRNAs) have been crucially involved in the development of CVDs. Piwi-interacting RNAs (piRNAs) are a novel cluster of small non-coding RNAs with strong uracil bias at the 5' end and 2'-O-met...

    journal_title:Angiogenesis

    pub_type: 杂志文章,评审

    doi:10.1007/s10456-020-09750-w

    authors: Li M,Yang Y,Wang Z,Zong T,Fu X,Aung LHH,Wang K,Wang JX,Yu T

    更新日期:2020-10-04 00:00:00

  • Targeting endothelial thioredoxin-interacting protein (TXNIP) protects from metabolic disorder-related impairment of vascular function and post-ischemic revascularisation.

    abstract:INTRODUCTION:Although thioredoxin-interacting protein (TXNIP) is involved in a variety of biological functions, the contribution of endothelial TXNIP has not been well-defined in regards to endothelial and vascular function or in post-ischemic revascularisation. We postulated that inhibition of endothelial TXNIP with s...

    journal_title:Angiogenesis

    pub_type: 杂志文章

    doi:10.1007/s10456-019-09704-x

    authors: Domingues A,Boisson-Vidal C,Marquet de Rouge P,Dizier B,Sadoine J,Mignon V,Vessières E,Henrion D,Escriou V,Bigey P,Chaussain C,Smadja DM,Nivet-Antoine V

    更新日期:2020-05-01 00:00:00

  • Models and molecular mechanisms of blood vessel co-option by cancer cells.

    abstract::Cancer cells have diverse mechanisms for utilizing the vasculature; they can initiate the formation of new blood vessels from preexisting ones (sprouting angiogenesis) or they can form cohesive interactions with the abluminal surface of preexisting vasculature in the absence of sprouting (co-option). The later process...

    journal_title:Angiogenesis

    pub_type: 杂志文章,评审

    doi:10.1007/s10456-019-09684-y

    authors: Zhang Y,Wang S,Dudley AC

    更新日期:2020-02-01 00:00:00

  • Revascularization after angiogenesis inhibition favors new sprouting over abandoned vessel reuse.

    abstract::Inhibiting pathologic angiogenesis can halt disease progression, but such inhibition may offer only a temporary benefit, followed by tissue revascularization after treatment stoppage. This revascularization, however, occurs by largely unknown phenotypic changes in pathologic vessels. To investigate the dynamics of ves...

    journal_title:Angiogenesis

    pub_type: 杂志文章

    doi:10.1007/s10456-019-09679-9

    authors: Mukwaya A,Mirabelli P,Lennikov A,Thangavelu M,Ntzouni M,Jensen L,Peebo B,Lagali N

    更新日期:2019-11-01 00:00:00

  • Intramuscular fast-flow vascular anomaly contains somatic MAP2K1 and KRAS mutations.

    abstract:BACKGROUND:The term "intramuscular hemangioma capillary type" (IHCT) refers to a fast-flow vascular lesion that is classified as a tumor, although its phenotype overlaps with arteriovenous malformation (AVM). The purpose of this study was to identify somatic mutations in IHCT. METHODS:Affected tissue specimens were ob...

    journal_title:Angiogenesis

    pub_type: 杂志文章

    doi:10.1007/s10456-019-09678-w

    authors: Goss JA,Konczyk DJ,Smits PJ,Kozakewich HPW,Alomari AI,Al-Ibraheemi A,Taghinia AH,Dickie BH,Adams DM,Fishman SJ,Mulliken JB,Warman ML,Greene AK

    更新日期:2019-11-01 00:00:00

  • Adgrf5 contributes to patterning of the endothelial deep layer in retina.

    abstract::Neovascularization of the inner retinal space is a major cause of vision loss. In retinal angiomatous proliferation (RAP) syndrome, newly formed vessels originate from the retinal plexus and invade the inner retinal space. However, the molecular pathways preventing subretinal vascularization remain largely unknown. In...

    journal_title:Angiogenesis

    pub_type: 杂志文章

    doi:10.1007/s10456-019-09674-0

    authors: Niaudet C,Petkova M,Jung B,Lu S,Laviña B,Offermanns S,Brakebusch C,Betsholtz C

    更新日期:2019-11-01 00:00:00

  • Anti-secretogranin III therapy of oxygen-induced retinopathy with optimal safety.

    abstract::Retinopathy of prematurity (ROP) with pathological retinal neovascularization is the most common cause of blindness in children. ROP is currently treated with laser therapy or cryotherapy, both of which may adversely affect the peripheral vision with limited efficacy. Owing to the susceptibility of the developing reti...

    journal_title:Angiogenesis

    pub_type: 杂志文章

    doi:10.1007/s10456-019-09662-4

    authors: Tang F,LeBlanc ME,Wang W,Liang D,Chen P,Chou TH,Tian H,Li W

    更新日期:2019-08-01 00:00:00

  • Prognostic effect of VEGF gene variants in metastatic non-small-cell lung cancer patients.

    abstract:INTRODUCTION:Clinical and pathological characteristics are still considered prognostic markers in metastatic non-small-cell lung cancer (NSCLC) patients but they cannot explain all interindividual variability. Tumoral angiogenesis mediated by the vascular endothelial growth factor (VEGF) is critical for the progression...

    journal_title:Angiogenesis

    pub_type: 杂志文章

    doi:10.1007/s10456-019-09668-y

    authors: Sullivan I,Riera P,Andrés M,Altés A,Majem M,Blanco R,Capdevila L,Barba A,Barnadas A,Salazar J

    更新日期:2019-08-01 00:00:00

  • AutoTube: a novel software for the automated morphometric analysis of vascular networks in tissues.

    abstract::Due to their involvement in many physiologic and pathologic processes, there is a great interest in identifying new molecular pathways that mediate the formation and function of blood and lymphatic vessels. Vascular research increasingly involves the image-based analysis and quantification of vessel networks in tissue...

    journal_title:Angiogenesis

    pub_type: 杂志文章

    doi:10.1007/s10456-018-9652-3

    authors: Montoya-Zegarra JA,Russo E,Runge P,Jadhav M,Willrodt AH,Stoma S,Nørrelykke SF,Detmar M,Halin C

    更新日期:2019-05-01 00:00:00

  • Angiogenic desmoplastic histopathological growth pattern as a prognostic marker of good outcome in patients with colorectal liver metastases.

    abstract:BACKGROUND:In patients with resectable colorectal liver metastases (CRLM), distinct histopathological growth patterns (HGPs) develop at the interface between the tumour and surrounding tissue. The desmoplastic (d) HGP is characterised by angiogenesis and a peripheral fibrotic rim, whereas non-angiogenic HGPs co-opt end...

    journal_title:Angiogenesis

    pub_type: 杂志文章

    doi:10.1007/s10456-019-09661-5

    authors: Galjart B,Nierop PMH,van der Stok EP,van den Braak RRJC,Höppener DJ,Daelemans S,Dirix LY,Verhoef C,Vermeulen PB,Grünhagen DJ

    更新日期:2019-05-01 00:00:00

  • Activin receptor-like kinase 1 is associated with immune cell infiltration and regulates CLEC14A transcription in cancer.

    abstract::Cancer cells sustain their metabolic needs through nutrients and oxygen supplied by the bloodstream. The requirement for tumor angiogenesis has been therapeutically exploited in the clinical setting mainly by means of inhibition of the vascular endothelial growth factor family of ligands and receptors. Despite promisi...

    journal_title:Angiogenesis

    pub_type: 临床试验,杂志文章

    doi:10.1007/s10456-018-9642-5

    authors: Bocci M,Sjölund J,Kurzejamska E,Lindgren D,Marzouka NA,Bartoschek M,Höglund M,Pietras K

    更新日期:2019-02-01 00:00:00

  • CMTM4 regulates angiogenesis by promoting cell surface recycling of VE-cadherin to endothelial adherens junctions.

    abstract::Vascular endothelial (VE) cadherin is a key component of endothelial adherens junctions (AJs) and plays an important role in maintaining vascular integrity. Endocytosis of VE-cadherin regulates junctional strength and a decrease of surface VE-cadherin reduces vascular stability. However, disruption of AJs is also a re...

    journal_title:Angiogenesis

    pub_type: 杂志文章

    doi:10.1007/s10456-018-9638-1

    authors: Chrifi I,Louzao-Martinez L,Brandt MM,van Dijk CGM,Bürgisser PE,Zhu C,Kros JM,Verhaar MC,Duncker DJ,Cheng C

    更新日期:2019-02-01 00:00:00

  • Pazopanib may reduce bleeding in hereditary hemorrhagic telangiectasia.

    abstract::Pazopanib (Votrient) is an orally administered tyrosine kinase inhibitor that blocks VEGF receptors potentially serving as anti-angiogenic treatment for hereditary hemorrhagic telangiectasia (HHT). We report a prospective, multi-center, open-label, dose-escalating study [50 mg, 100 mg, 200 mg, and 400 mg], designed as...

    journal_title:Angiogenesis

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1007/s10456-018-9646-1

    authors: Faughnan ME,Gossage JR,Chakinala MM,Oh SP,Kasthuri R,Hughes CCW,McWilliams JP,Parambil JG,Vozoris N,Donaldson J,Paul G,Berry P,Sprecher DL

    更新日期:2019-02-01 00:00:00

  • miR-153 inhibits the migration and the tube formation of endothelial cells by blocking the paracrine of angiopoietin 1 in breast cancer cells.

    abstract::The sprouting of endothelial cells is the first step of tumor angiogenesis. Our previous study suggests that miR-153 suppresses breast tumor angiogenesis partially through targeting hypoxia-induced factor (HIF1α). In this study, we demonstrated that miR-153 also suppresses the migration and the tube formation of endot...

    journal_title:Angiogenesis

    pub_type: 杂志文章

    doi:10.1007/s10456-018-9630-9

    authors: Liang H,Ge F,Xu Y,Xiao J,Zhou Z,Liu R,Chen C

    更新日期:2018-11-01 00:00:00

  • EphB4 mediates resistance to antiangiogenic therapy in experimental glioma.

    abstract:INTRODUCTION:Alterations in vascular morphogenesis are hallmarks of antiangiogenesis-resistant tumor vessels. Vascular morphogenesis is regulated by ephrinB2-EphB4 system which may induce different biological effects depending on the oncological and molecular contexts. It was the aim of the current study to characteriz...

    journal_title:Angiogenesis

    pub_type: 杂志文章

    doi:10.1007/s10456-018-9633-6

    authors: Uhl C,Markel M,Broggini T,Nieminen M,Kremenetskaia I,Vajkoczy P,Czabanka M

    更新日期:2018-11-01 00:00:00

  • Characterization of a drug-targetable allosteric site regulating vascular endothelial growth factor signaling.

    abstract::Vascular endothelial growth factors (VEGFs) regulate blood and lymph vessel development upon activation of three receptor tyrosine kinases (VEGFRs). The extracellular domain of VEGFRs consists of seven Ig-homology domains, of which D2-3 form the ligand-binding site, while the membrane proximal domains D4-7 are involve...

    journal_title:Angiogenesis

    pub_type: 杂志文章

    doi:10.1007/s10456-018-9606-9

    authors: Thieltges KM,Avramovic D,Piscitelli CL,Markovic-Mueller S,Binz HK,Ballmer-Hofer K

    更新日期:2018-08-01 00:00:00

  • Visualization of endothelial cell cycle dynamics in mouse using the Flt-1/eGFP-anillin system.

    abstract::Endothelial cell proliferation is a key process during vascular growth but its kinetics could only be assessed in vitro or ex vivo so far. To enable the monitoring and quantification of cell cycle kinetics in vivo, we have generated transgenic mice expressing an eGFP-anillin construct under control of the endothelial-...

    journal_title:Angiogenesis

    pub_type: 杂志文章

    doi:10.1007/s10456-018-9601-1

    authors: Herz K,Becker A,Shi C,Ema M,Takahashi S,Potente M,Hesse M,Fleischmann BK,Wenzel D

    更新日期:2018-05-01 00:00:00

  • Time-dependent LXR/RXR pathway modulation characterizes capillary remodeling in inflammatory corneal neovascularization.

    abstract::Inflammation in the normally immune-privileged cornea can initiate a pathologic angiogenic response causing vision-threatening corneal neovascularization. Inflammatory pathways, however, are numerous, complex and are activated in a time-dependent manner. Effective resolution of inflammation and associated angiogenesis...

    journal_title:Angiogenesis

    pub_type: 杂志文章

    doi:10.1007/s10456-018-9604-y

    authors: Mukwaya A,Lennikov A,Xeroudaki M,Mirabelli P,Lachota M,Jensen L,Peebo B,Lagali N

    更新日期:2018-05-01 00:00:00

  • Oxidized phospholipids stimulate production of stem cell factor via NRF2-dependent mechanisms.

    abstract::Receptor tyrosine kinase c-Kit and its ligand stem cell factor (SCF) regulate resident vascular wall cells and recruit circulating progenitors. We tested whether SCF may be induced by oxidized palmitoyl-arachidonoyl-phosphatidylcholine (OxPAPC) known to accumulate in atherosclerotic vessels. Gene expression analysis d...

    journal_title:Angiogenesis

    pub_type: 杂志文章

    doi:10.1007/s10456-017-9590-5

    authors: Afonyushkin T,Oskolkova OV,Bochkov VN

    更新日期:2018-05-01 00:00:00

  • Pharmacological intervention of MKL/SRF signaling by CCG-1423 impedes endothelial cell migration and angiogenesis.

    abstract::De novo synthesis of cytoskeleton-regulatory proteins triggered by the megakaryoblastic leukemia (MKL)/serum response factor (SRF) transcriptional system in response to pro-angiogenic growth factors lies at the heart of endothelial cell (EC) migration (a critical element of angiogenesis) and neovascularization. This s...

    journal_title:Angiogenesis

    pub_type: 杂志文章

    doi:10.1007/s10456-017-9560-y

    authors: Gau D,Veon W,Capasso TL,Bottcher R,Shroff S,Roman BL,Roy P

    更新日期:2017-11-01 00:00:00

  • PDGFRβ-P2A-CreERT2 mice: a genetic tool to target pericytes in angiogenesis.

    abstract::Pericytes are essential mural cells distinguished by their association with small caliber blood vessels and the presence of a basement membrane shared with endothelial cells. Pericyte interaction with the endothelium plays an important role in angiogenesis; however, very few tools are currently available that allow fo...

    journal_title:Angiogenesis

    pub_type: 杂志文章

    doi:10.1007/s10456-017-9570-9

    authors: Cuervo H,Pereira B,Nadeem T,Lin M,Lee F,Kitajewski J,Lin CS

    更新日期:2017-11-01 00:00:00

  • Early prediction of tumor response to bevacizumab treatment in murine colon cancer models using three-dimensional dynamic contrast-enhanced ultrasound imaging.

    abstract::Due to spatial tumor heterogeneity and consecutive sampling errors, it is critically important to assess treatment response following antiangiogenic therapy in three dimensions as two-dimensional assessment has been shown to substantially over- and underestimate treatment response. In this study, we evaluated whether ...

    journal_title:Angiogenesis

    pub_type: 杂志文章

    doi:10.1007/s10456-017-9566-5

    authors: Zhou J,Zhang H,Wang H,Lutz AM,El Kaffas A,Tian L,Hristov D,Willmann JK

    更新日期:2017-11-01 00:00:00

  • RCAN1.4 regulates VEGFR-2 internalisation, cell polarity and migration in human microvascular endothelial cells.

    abstract::Regulator of calcineurin 1 (RCAN1) is an endogenous inhibitor of the calcineurin pathway in cells. It is expressed as two isoforms in vertebrates: RCAN1.1 is constitutively expressed in most tissues, whereas transcription of RCAN1.4 is induced by several stimuli that activate the calcineurin-NFAT pathway. RCAN1.4 is h...

    journal_title:Angiogenesis

    pub_type: 杂志文章

    doi:10.1007/s10456-017-9542-0

    authors: Alghanem AF,Wilkinson EL,Emmett MS,Aljasir MA,Holmes K,Rothermel BA,Simms VA,Heath VL,Cross MJ

    更新日期:2017-08-01 00:00:00

  • The clinical application of angiostatic therapy in combination with radiotherapy: past, present, future.

    abstract::Although monotherapy with angiostatic drugs is still far from effective, there is abundant evidence that angiostatic therapy can improve the efficacy of conventional treatments like radiotherapy. This has instigated numerous efforts to optimize and clinically implement the combination of angiostatic drugs with radiati...

    journal_title:Angiogenesis

    pub_type: 历史文章,杂志文章,评审

    doi:10.1007/s10456-017-9546-9

    authors: Hamming LC,Slotman BJ,Verheul HMW,Thijssen VL

    更新日期:2017-05-01 00:00:00

  • Angiopoietins as serum biomarkers for lymphatic anomalies.

    abstract::Vascular anomalies can cause significant morbidity and mortality. Advances in diagnosis will be improved if noninvasive biomarkers can be identified, as obtaining a tissue biopsy can worsen the disease and precipitate complications. The goal of this study was to identify biomarkers for vascular anomaly patients to aid...

    journal_title:Angiogenesis

    pub_type: 杂志文章

    doi:10.1007/s10456-016-9537-2

    authors: Le Cras TD,Mobberley-Schuman PS,Broering M,Fei L,Trenor CC 3rd,Adams DM

    更新日期:2017-02-01 00:00:00

  • The role of endoglin in post-ischemic revascularization.

    abstract::Following arterial occlusion, blood vessels respond by forming a new network of functional capillaries (angiogenesis), by reorganizing preexisting capillaries through the recruitment of smooth muscle cells to generate new arteries (arteriogenesis) and by growing and remodeling preexisting collateral arterioles into ph...

    journal_title:Angiogenesis

    pub_type: 杂志文章,评审

    doi:10.1007/s10456-016-9535-4

    authors: Núñez-Gómez E,Pericacho M,Ollauri-Ibáñez C,Bernabéu C,López-Novoa JM

    更新日期:2017-02-01 00:00:00

  • Identification of HIF-2α-regulated genes that play a role in human microvascular endothelial sprouting during prolonged hypoxia in vitro.

    abstract::During prolonged hypoxic conditions, endothelial cells change their gene expression to adjust to the low oxygen environment. This process is mainly regulated by the hypoxia-inducible factors, HIF-1α and HIF-2α. Although endothelial cells do not form sprouts during prolonged hypoxic culturing, silencing of HIF-2α parti...

    journal_title:Angiogenesis

    pub_type: 杂志文章

    doi:10.1007/s10456-016-9527-4

    authors: Nauta TD,van den Broek M,Gibbs S,van der Pouw-Kraan TC,Oudejans CB,van Hinsbergh VW,Koolwijk P

    更新日期:2017-02-01 00:00:00

  • Plants and their active compounds: natural molecules to target angiogenesis.

    abstract::Angiogenesis, or new blood vessel formation, is an important process in the pathogenesis of several diseases and thus has been targeted for the prevention and treatment for many disorders. However, the anti-angiogenic agents that are currently in use are mainly synthetic compounds and humanized monoclonal antibodies, ...

    journal_title:Angiogenesis

    pub_type: 杂志文章,评审

    doi:10.1007/s10456-016-9512-y

    authors: Lu K,Bhat M,Basu S

    更新日期:2016-07-01 00:00:00

  • Suppression of vascular network formation by chronic hypoxia and prolyl-hydroxylase 2 (phd2) deficiency during vertebrate development.

    abstract::In the adult, new vessels and red blood cells form in response to hypoxia. Here, the oxygen-sensing system (PHD-HIF) has recently been put into focus, since the prolyl-hydroxylase domain proteins (PHD) and hypoxia-inducible factors (HIF) are considered as potential therapeutic targets to treat ischemia, cancers or age...

    journal_title:Angiogenesis

    pub_type: 杂志文章

    doi:10.1007/s10456-015-9492-3

    authors: Metikala S,Neuhaus H,Hollemann T

    更新日期:2016-04-01 00:00:00

  • Tumor vasculogenic mimicry predicts poor prognosis in cancer patients: a meta-analysis.

    abstract:BACKGROUND:Vasculogenic mimicry (VM) is the formation of vascular channels by tumor cells or tumor cell-derived, trans-differentiated cells in highly aggressive, solid tumors. However, the disease features and prognostic value of VM for overall survival of cancer patients remain controversial. METHOD:To systematically...

    journal_title:Angiogenesis

    pub_type: 杂志文章,meta分析

    doi:10.1007/s10456-016-9500-2

    authors: Yang JP,Liao YD,Mai DM,Xie P,Qiang YY,Zheng LS,Wang MY,Mei Y,Meng DF,Xu L,Cao L,Yang Q,Yang XX,Wang WB,Peng LX,Huang BJ,Qian CN

    更新日期:2016-04-01 00:00:00

  • In situ validation of VEGFR-2 and α v ß 3 integrin as targets for breast lesion characterization.

    abstract::Vascular endothelial growth factor receptor 2 (VEGFR-2) and α v ß 3 integrin are the most frequently addressed targets in molecular imaging of tumor angiogenesis. In preclinical studies, molecular imaging of angiogenesis has shown potential to detect and differentiate benign and malignant lesions of the breast. Thus, ...

    journal_title:Angiogenesis

    pub_type: 杂志文章

    doi:10.1007/s10456-016-9499-4

    authors: Ehling J,Misiewicz M,von Stillfried S,Möckel D,Bzyl J,Pochon S,Lederle W,Knuechel R,Lammers T,Palmowski M,Kiessling F

    更新日期:2016-04-01 00:00:00

  • Matrix Gla protein regulates differentiation of endothelial cells derived from mouse embryonic stem cells.

    abstract::Matrix Gla protein (MGP) is an antagonist of bone morphogenetic proteins and expressed in vascular endothelial cells. Lack of MGP causes vascular abnormalities in multiple organs in mice. The objective of this study is to define the role of MGP in early endothelial differentiation. We find that expression of endotheli...

    journal_title:Angiogenesis

    pub_type: 杂志文章

    doi:10.1007/s10456-015-9484-3

    authors: Yao J,Guihard PJ,Blazquez-Medela AM,Guo Y,Liu T,Boström KI,Yao Y

    更新日期:2016-01-01 00:00:00

  • KSHV induces aerobic glycolysis and angiogenesis through HIF-1-dependent upregulation of pyruvate kinase 2 in Kaposi's sarcoma.

    abstract::Kaposi's sarcoma (KS) is a vascular neoplasm caused by infection of endothelial or endothelial precursor cells with the Kaposi's sarcoma-associated herpesvirus (KSHV/HHV8). Research efforts have focused on defining the molecular events explaining how KSHV promotes pathological angiogenesis and KS tumor formation. mTOR...

    journal_title:Angiogenesis

    pub_type: 杂志文章

    doi:10.1007/s10456-015-9475-4

    authors: Ma T,Patel H,Babapoor-Farrokhran S,Franklin R,Semenza GL,Sodhi A,Montaner S

    更新日期:2015-10-01 00:00:00

  • Tumor-derived microRNA-494 promotes angiogenesis in non-small cell lung cancer.

    abstract::Angiogenesis, a crucial step in tumor growth and metastasis, is regulated by various pro- or anti-angiogenic factors. Recently, microRNAs have been shown to modulate angiogenic processes by modulating the expression of critical angiogenic factors. However, roles of tumor-derived microRNAs in regulating tumor vasculari...

    journal_title:Angiogenesis

    pub_type: 杂志文章

    doi:10.1007/s10456-015-9474-5

    authors: Mao G,Liu Y,Fang X,Liu Y,Fang L,Lin L,Liu X,Wang N

    更新日期:2015-07-01 00:00:00

  • Contrast-enhanced molecular ultrasound differentiates endoglin genotypes in mouse embryos.

    abstract::Targeted ultrasound contrast imaging has the potential to become a reliable molecular imaging tool. A better understanding of the quantitative aspects of molecular ultrasound technology could facilitate the translation of this technique to the clinic for the purposes of assessing vascular pathology and detecting indiv...

    journal_title:Angiogenesis

    pub_type: 杂志文章

    doi:10.1007/s10456-014-9447-0

    authors: Denbeigh JM,Nixon BA,Lee JJ,Jerkic M,Marsden PA,Letarte M,Puri MC,Foster FS

    更新日期:2015-01-01 00:00:00

  • TM4SF1: a new vascular therapeutic target in cancer.

    abstract::Transmembrane-4 L-six family member-1 (TM4SF1) is a small plasma membrane glycoprotein that regulates cell motility and proliferation. TM4SF1 is an attractive cancer target because of its high expression in both tumor cells and on the vascular endothelial cells lining tumor blood vessels. We generated mouse monoclonal...

    journal_title:Angiogenesis

    pub_type: 杂志文章

    doi:10.1007/s10456-014-9437-2

    authors: Lin CI,Merley A,Sciuto TE,Li D,Dvorak AM,Melero-Martin JM,Dvorak HF,Jaminet SC

    更新日期:2014-10-01 00:00:00

  • Angiopoietin-like 7, a novel pro-angiogenetic factor over-expressed in cancer.

    abstract::Angiopoietin-like (ANGPTL) proteins are secreted proteins showing structural similarity to members of the angiopoietin family. Some ANGPTL proteins possess pleiotropic activities, being involved in cancer lipid, glucose energy metabolisms, and angiogenesis. ANGPTL7 is the less characterized member of the family whose ...

    journal_title:Angiogenesis

    pub_type: 杂志文章

    doi:10.1007/s10456-014-9435-4

    authors: Parri M,Pietrovito L,Grandi A,Campagnoli S,De Camilli E,Bianchini F,Marchiò S,Bussolino F,Jin B,Sarmientos P,Grandi G,Viale G,Pileri P,Chiarugi P,Grifantini R

    更新日期:2014-10-01 00:00:00

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