听力与言语-语言病理学

行为科学

医学伦理学

你正在浏览Frontiers in Immunology期刊下所有文献
  • Dynamics of Systemic Inflammation as a Function of Developmental Stage in Pediatric Acute Liver Failure.

    abstract::The Pediatric Acute Liver Failure (PALF) study is a multicenter, observational cohort study of infants and children diagnosed with this complex clinical syndrome. Outcomes in PALF reflect interactions among the child's clinical condition, response to supportive care, disease severity, potential for recovery, and, if n...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章

    doi:10.3389/fimmu.2020.610861

    authors: Vodovotz Y,Barclay D,Yin J,Squires RH,Zamora R

    更新日期:2021-01-15 00:00:00

  • Extracellular Vesicles in Rheumatoid Arthritis and Systemic Lupus Erythematosus: Functions and Applications.

    abstract::In the last two decades, extracellular vesicles (EVs) have aroused wide interest among researchers in basic and clinical research. EVs, small membrane vesicles are released by almost all kinds of cells into the extracellular environment. According to many recent studies, EVs participate in immunomodulation and play an...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章,评审

    doi:10.3389/fimmu.2020.575712

    authors: Zhang B,Zhao M,Lu Q

    更新日期:2021-01-14 00:00:00

  • Peripheral Immune Cell Ratios and Clinical Outcomes in Seropositive Autoimmune Encephalitis: A Study by the Australian Autoimmune Encephalitis Consortium.

    abstract:Objective:To examine the utility of the peripheral blood neutrophil-to-lymphocyte ratio (NLR) and monocyte-to-lymphocyte ratio (MLR) as biomarkers of prognosis in seropositive autoimmune encephalitis (AE). Methods:In this multicenter study, we retrospectively analyzed 57 cases of seropositive AE with hospital admissio...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章

    doi:10.3389/fimmu.2020.597858

    authors: Broadley J,Wesselingh R,Seneviratne U,Kyndt C,Beech P,Buzzard K,Nesbitt C,D'Souza W,Brodtmann A,Kalincik T,Butzkueven H,O'Brien TJ,Monif M,Australian Autoimmune Encephalitis Consortium.

    更新日期:2021-01-14 00:00:00

  • Activation of the Complement System in the Lower Genital Tract During Pregnancy and Delivery.

    abstract:Background:Human pregnancy alters profoundly the immune system. The local involvement and mechanisms of activation of the complement system in the cervicovaginal milieu during pregnancy and delivery remain unexplored. Objectives:To determine whether normal pregnancy and delivery are associated with local activation of...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章

    doi:10.3389/fimmu.2020.563073

    authors: Livson S,Jarva H,Kalliala I,Lokki AI,Heikkinen-Eloranta J,Nieminen P,Meri S

    更新日期:2021-01-11 00:00:00

  • RIG-I Has a Role in Immunity Against Haemonchus contortus, a Gastrointestinal Parasite in Ovis aries: A Novel Report.

    abstract::Retinoic acid inducible gene I (RIG-I) is associated to the DExD/H box RNA helicases. It is a pattern recognition receptor (PRR), playing a crucial role in the system and is a germ line encoded host sensor to perceive pathogen-associated molecular patterns (PAMPs). So far, reports are available for the role of RIG-I i...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章

    doi:10.3389/fimmu.2020.534705

    authors: Banerjee S,Pal A,Pal A,Mandal SC,Chatterjee PN,Chatterjee JK

    更新日期:2021-01-08 00:00:00

  • Engineering of Humanized Antibodies Against Human Interleukin 5 Receptor Alpha Subunit That Cause Potent Antibody-Dependent Cell-Mediated Cytotoxicity.

    abstract::Patients with severe eosinophilic asthma (SEA; characterized by persistent eosinophilia in blood and airway tissues) experience frequent asthma exacerbations with poor clinical outcomes. Interleukin 5 (IL-5) and IL-5 receptor alpha subunit (IL-5α) play key roles in eosinophilia maintenance, and relevant therapeutic st...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章

    doi:10.3389/fimmu.2020.593748

    authors: Kim JE,Lee DH,Jung K,Kim EJ,Choi Y,Park HS,Kim YS

    更新日期:2021-01-08 00:00:00

  • Geographical Distribution, Incidence, Malignancies, and Outcome of 136 Eastern Slavic Patients With Nijmegen Breakage Syndrome and NBN Founder Variant c.657_661del5.

    abstract::Nijmegen breakage syndrome (NBS) is a DNA repair disorder characterized by combined immunodeficiency and a high predisposition to lymphoid malignancies. The majority of NBS patients are identified with a homozygous five base pair deletion in the Nibrin (NBN) gene (c.657_661del5, p.K219fsX19) with a founder effect obse...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章

    doi:10.3389/fimmu.2020.602482

    authors: Sharapova SO,Pashchenko OE,Bondarenko AV,Vakhlyarskaya SS,Prokofjeva T,Fedorova AS,Savchak I,Mareika Y,Valiev TT,Popa A,Tuzankina IA,Vlasova EV,Sakovich IS,Polyakova EA,Rumiantseva NV,Naumchik IV,Kulyova SA,Aleshkevich

    更新日期:2021-01-08 00:00:00

  • Pronounced Diurnal Pattern of Salivary C-Reactive Protein (CRP) With Modest Associations to Circulating CRP Levels.

    abstract::C-reactive protein (CRP), a humoral component of the innate immune system with important functions in host-defense, is extensively used as a sensitive biomarker of systemic inflammation. During inflammation, hepatocyte-derived CRP rises dramatically in the blood due to increased interleukin-6 (IL-6) levels. Reliable d...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章

    doi:10.3389/fimmu.2020.607166

    authors: Wetterö J,von Löhneysen S,Cobar F,Kristenson M,Garvin P,Sjöwall C

    更新日期:2021-01-08 00:00:00

  • PD-L1/PD-1 Pattern of Expression Within the Bone Marrow Immune Microenvironment in Smoldering Myeloma and Active Multiple Myeloma Patients.

    abstract:Background:The PD-1/PD-L1 axis has recently emerged as an immune checkpoint that controls antitumor immune responses also in hematological malignancies. However, the use of anti-PD-L1/PD-1 antibodies in multiple myeloma (MM) patients still remains debated, at least in part because of discordant literature data on PD-L1...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章

    doi:10.3389/fimmu.2020.613007

    authors: Costa F,Vescovini R,Marchica V,Storti P,Notarfranchi L,Dalla Palma B,Toscani D,Burroughs-Garcia J,Catarozzo MT,Sammarelli G,Giuliani N

    更新日期:2021-01-08 00:00:00

  • SARS-CoV-2 Viral RNA Shedding for More Than 87 Days in an Individual With an Impaired CD8+ T Cell Response.

    abstract::Prolonged shedding of viral RNA occurs in some individuals following SARS-CoV-2 infection. We perform comprehensive immunologic evaluation of one individual with prolonged shedding. The case subject recovered from severe COVID-19 and tested positive for SARS-CoV-2 viral RNA repeatedly as many as 87 days after the firs...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章

    doi:10.3389/fimmu.2020.618402

    authors: Turner JS,Day A,Alsoussi WB,Liu Z,O'Halloran JA,Presti RM,Patterson BK,Whelan SPJ,Ellebedy AH,Mudd PA

    更新日期:2021-01-08 00:00:00

  • IL-23 Contributes to Campylobacter jejuni-Induced Intestinal Pathology via Promoting IL-17 and IFNγ Responses by Innate Lymphoid Cells.

    abstract::Human pathogen Campylobacter jejuni is a significant risk factor for the development of long-term intestinal dysfunction although the cellular and molecular mechanisms remain scantily defined. IL-23 is an emerging therapeutic target for the treatment of inflammatory intestinal diseases, however its role in C. jejuni-d...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章

    doi:10.3389/fimmu.2020.579615

    authors: Jing X,Korchagina AA,Shein SA,Muraoka WT,Koroleva E,Tumanov AV

    更新日期:2021-01-06 00:00:00

  • Immunomodulation Induced During Interferon-α Therapy Impairs the Anti-HBV Immune Response Through CD24+CD38hi B Cells.

    abstract::Type I interferon is widely used for antiviral therapy, yet has yielded disappointing results toward chronic HBV infection. Here we identify that PEG-IFNα-2b therapy toward persistent infection in humans is a double-edged sword of both immunostimulation and immunomodulation. Our studies of this randomised trial showed...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章

    doi:10.3389/fimmu.2020.591269

    authors: Fu B,Wang D,Shen X,Guo C,Liu Y,Ye Y,Sun R,Li J,Tian Z,Wei H

    更新日期:2020-12-23 00:00:00

  • Environmental Factor-Mediated Transgenerational Inheritance of Igf2r Hypomethylation and Pulmonary Allergic Response via Targeting Dendritic Cells.

    abstract::The developmental origin of allergic diseases has been suggested, but the molecular basis remains enigmatic. Exposure to environmental factors, such as di-(2-ethylhexyl) phthalate (DEHP; a common plasticizer), is suggested to be associated with increased childhood allergic asthma, but the causal relationship and its u...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章

    doi:10.3389/fimmu.2020.603831

    authors: Suen JL,Wu TT,Li YH,Lee CL,Kuo FC,Yan PS,Wu CF,Tran M,Wang CJ,Hung CH,Wu MT,Chan MWY,Huang SK

    更新日期:2020-12-23 00:00:00

  • Distinguishing Sepsis From Infection by Neutrophil Dysfunction: A Promising Role of CXCR2 Surface Level.

    abstract::Sepsis is one of the well-established diseases with specific patterns of neutrophil dysfunctions. Previous studies demonstrated sepsis-related neutrophil dysfunctions in comparison with subjects without infection. Since sepsis and infection are recently recognized as distinctive processes, whether these neutrophil dys...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章

    doi:10.3389/fimmu.2020.608696

    authors: Seree-Aphinan C,Vichitkunakorn P,Navakanitworakul R,Khwannimit B

    更新日期:2020-12-23 00:00:00

  • Short-Chain Fatty Acids Promote Intracellular Bactericidal Activity in Head Kidney Macrophages From Turbot (Scophthalmus maximus L.) via Hypoxia Inducible Factor-1α.

    abstract::Short-chain fatty acids (SCFAs) are mainly produced by microbiota through the fermentation of carbohydrates in the intestine. Acetate, propionate, and butyrate are the most abundant SCFA metabolites and have been shown to be important in the maintenance of host health. In this study, head kidney macrophages (HKMs) wer...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章

    doi:10.3389/fimmu.2020.615536

    authors: Zhang J,Zhang H,Liu M,Lan Y,Sun H,Mai K,Wan M

    更新日期:2020-12-23 00:00:00

  • Heme as Possible Contributing Factor in the Evolvement of Shiga-Toxin Escherichia coli Induced Hemolytic-Uremic Syndrome.

    abstract::Shiga-toxin (Stx)-producing Escherichia coli hemolytic-uremic syndrome (STEC-HUS) is one of the most common causes of acute kidney injury in children. Stx-mediated endothelial injury initiates the cascade leading to thrombotic microangiopathy (TMA), still the exact pathogenesis remains elusive. Interestingly, there is...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章

    doi:10.3389/fimmu.2020.547406

    authors: Wijnsma KL,Veissi ST,de Wijs S,van der Velden T,Volokhina EB,Wagener FADTG,van de Kar NCAJ,van den Heuvel LP

    更新日期:2020-12-22 00:00:00

  • RNA Vaccines: A Suitable Platform for Tackling Emerging Pandemics?

    abstract::The COVID-19 pandemic demonstrates the ongoing threat of pandemics caused by novel, previously unrecognized, or mutated pathogens with high transmissibility. Currently, vaccine development is too slow for vaccines to be used in the control of emerging pandemics. RNA-based vaccines might be suitable to meet this challe...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章,评审

    doi:10.3389/fimmu.2020.608460

    authors: Sandbrink JB,Shattock RJ

    更新日期:2020-12-22 00:00:00

  • Bidirectional Action of Cenicriviroc, a CCR2/CCR5 Antagonist, Results in Alleviation of Pain-Related Behaviors and Potentiation of Opioid Analgesia in Rats With Peripheral Neuropathy.

    abstract::Clinical management of neuropathic pain is unsatisfactory, mainly due to its resistance to the effects of available analgesics, including opioids. Converging evidence indicates the functional interactions between chemokine and opioid receptors and their influence on nociceptive processes. Recent studies highlight that...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章

    doi:10.3389/fimmu.2020.615327

    authors: Kwiatkowski K,Pawlik K,Ciapała K,Piotrowska A,Makuch W,Mika J

    更新日期:2020-12-21 00:00:00

  • Rapid Evolution of HERC6 and Duplication of a Chimeric HERC5/6 Gene in Rodents and Bats Suggest an Overlooked Role of HERCs in Mammalian Immunity.

    abstract::Studying the evolutionary diversification of mammalian antiviral defenses is of main importance to better understand our innate immune repertoire. The small HERC proteins are part of a multigene family, including HERC5 and HERC6, which have probably diversified through complex evolutionary history in mammals. Here, we...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章

    doi:10.3389/fimmu.2020.605270

    authors: Jacquet S,Pontier D,Etienne L

    更新日期:2020-12-18 00:00:00

  • Anti-CD2 Antibody-Coated Nanoparticles Containing IL-2 Induce NK Cells That Protect Lupus Mice via a TGF-β-Dependent Mechanism.

    abstract::We recently reported that the treatment with nanoparticles (NPs) loaded with tolerogenic cytokines suppressed the manifestations of lupus-like disease induced by the transfer of donor CD4+ T cells from DBA/2 mice into (C57BL/6 × DBA/2)F1 (BDF1) mice. Although the protective effects were ascribed to the induction of ad...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章

    doi:10.3389/fimmu.2020.583338

    authors: Horwitz DA,Liu A,Bickerton S,Castaldo G,Matarese G,Fahmy TM,La Cava A

    更新日期:2020-12-16 00:00:00

  • Different Innate and Adaptive Immune Responses to SARS-CoV-2 Infection of Asymptomatic, Mild, and Severe Cases.

    abstract::SARS-CoV-2 is a novel coronavirus, not encountered before by humans. The wide spectrum of clinical expression of SARS-CoV-2 illness suggests that individual immune responses to SARS-CoV-2 play a crucial role in determining the clinical course after first infection. Immunological studies have focused on patients with m...

    journal_title:Frontiers in immunology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.3389/fimmu.2020.610300

    authors: Carsetti R,Zaffina S,Piano Mortari E,Terreri S,Corrente F,Capponi C,Palomba P,Mirabella M,Cascioli S,Palange P,Cuccaro I,Milito C,Zumla A,Maeurer M,Camisa V,Vinci MR,Santoro A,Cimini E,Marchioni L,Nicastri E,Palmi

    更新日期:2020-12-16 00:00:00

  • Corrigendum: Comparative Analysis of G1P[8] Rotaviruses Identified Prior to Vaccine Implementation in Pakistan With Rotarix™ and RotaTeq™ Vaccine Strains.

    abstract::[This corrects the article DOI: 10.3389/fimmu.2020.562282.]. ...

    journal_title:Frontiers in immunology

    pub_type: 已发布勘误

    doi:10.3389/fimmu.2020.625157

    authors: Sadiq A,Bostan N

    更新日期:2020-12-16 00:00:00

  • Sharing CD4+ T Cell Loss: When COVID-19 and HIV Collide on Immune System.

    abstract::COVID-19 is a distinctive infection characterized by elevated inter-human transmission and presenting from absence of symptoms to severe cytokine storm that can lead to dismal prognosis. Like for HIV, lymphopenia and drastic reduction of CD4+ T cell counts in COVID-19 patients have been linked with poor clinical outco...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章,评审

    doi:10.3389/fimmu.2020.596631

    authors: Peng X,Ouyang J,Isnard S,Lin J,Fombuena B,Zhu B,Routy JP

    更新日期:2020-12-15 00:00:00

  • Systems Immunology Analysis Reveals an Immunomodulatory Effect of Snail-p53 Binding on Neutrophil- and T Cell-Mediated Immunity in KRAS Mutant Non-Small Cell Lung Cancer.

    abstract::Immunomodulation and chronic inflammation are important mechanisms utilized by cancer cells to evade the immune defense and promote tumor progression. Therefore, various efforts were focused on the development of approaches to reprogram the immune response to increase the immune detection of cancer cells and enhance p...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章

    doi:10.3389/fimmu.2020.569671

    authors: Hammoudeh SM,Venkatachalam T,Ansari AW,Bendardaf R,Hamid Q,Rahmani M,Hamoudi R

    更新日期:2020-12-14 00:00:00

  • MCAM/CD146 Signaling via PLCγ1 Leads to Activation of β1-Integrins in Memory T-Cells Resulting in Increased Brain Infiltration.

    abstract::Multiple sclerosis is a chronic auto-inflammatory disease of the central nervous system affecting patients worldwide. Neuroinflammation in multiple sclerosis is mainly driven by peripheral immune cells which invade the central nervous system and cause neurodegenerative inflammation. To enter the target tissue, immune ...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章

    doi:10.3389/fimmu.2020.599936

    authors: Zondler L,Herich S,Kotte P,Körner K,Schneider-Hohendorf T,Wiendl H,Schwab N,Zarbock A

    更新日期:2020-12-14 00:00:00

  • IL-2-Agonist-Induced IFN-γ Exacerbates Systemic Anaphylaxis in Food Allergen-Sensitized Mice.

    abstract::Food allergies are common, costly and potentially life-threatening disorders. They are driven by Th2, but inhibited by Th1 reactions. There is also evidence indicating that IL-2 agonist treatment inhibits allergic sensitization through expansion of regulatory T cells. Here, we tested the impact of an IL-2 agonist in a...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章

    doi:10.3389/fimmu.2020.596772

    authors: Link CWM,Rau CN,Udoye CC,Ragab M,Korkmaz RÜ,Comdühr S,Clauder AK,Lindemann T,Frehse B,Hofmann K,Almeida LN,Laumonnier Y,Beidaq AE,Finkelman FD,Manz RA

    更新日期:2020-12-11 00:00:00

  • Targeting IL-1β in the Treatment of Atherosclerosis.

    abstract::The role of inflammation in atherosclerosis has been recognized several decades ago and existing treatments provide benefits in part through non-specific anti-inflammatory actions. Compared with other cytokines, interleukin-1β (IL-1β) is associated with acute and chronic inflammation. Anti-inflammatory therapy with ca...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章,评审

    doi:10.3389/fimmu.2020.589654

    authors: Mai W,Liao Y

    更新日期:2020-12-10 00:00:00

  • Paving the Way Towards Universal Chimeric Antigen Receptor Therapy in Cancer Treatment: Current Landscape and Progress.

    abstract::Chimeric antigen receptor (CAR) therapy has been proved effective in a stream of clinical trials, especially in hematologic malignancies. However, current CAR therapy is highly personalized as cells used are derived from patients themselves, which can be costly, time-consuming, and sometimes fails to achieve optimal t...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章,评审

    doi:10.3389/fimmu.2020.604915

    authors: Zhang Y,Li P,Fang H,Wang G,Zeng X

    更新日期:2020-12-10 00:00:00

  • The Joint-Brain Axis: Insights From Rheumatoid Arthritis on the Crosstalk Between Chronic Peripheral Inflammation and the Brain.

    abstract::Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by erosive polyarthritis. Beyond joint pathology, RA is associated with neuropsychiatric comorbidity including depression, anxiety, and an increased risk to develop neurodegenerative diseases in later life. Studies investigating the central nerv...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章,评审

    doi:10.3389/fimmu.2020.612104

    authors: Süß P,Rothe T,Hoffmann A,Schlachetzki JCM,Winkler J

    更新日期:2020-12-10 00:00:00

  • Neutrophil Inflammatory Response Is Downregulated by Uptake of Superparamagnetic Iron Oxide Nanoparticle Therapeutics.

    abstract::Superparamagnetic iron oxide nanoparticles (SPION) are employed as diagnostics and therapeutics following intravenous delivery for the treatment of iron deficiency anemia (IDA) in adult patients with chronic kidney failure. Neutrophils are the first defense against blood borne foreign insult and recruit to vascular si...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章

    doi:10.3389/fimmu.2020.571489

    authors: Garcia G,Kim MH,Morikis VA,Simon SI

    更新日期:2020-12-09 00:00:00

  • Human Serum Albumin Binds Streptolysin O (SLO) Toxin Produced by Group A Streptococcus and Inhibits Its Cytotoxic and Hemolytic Effects.

    abstract::The pathogenicity of group A Streptococcus (GAS) is mediated by direct bacterial invasivity and toxin-associated damage. Among the extracellular products, the exotoxin streptolysin O (SLO) is produced by almost all GAS strains. SLO is a pore forming toxin (PFT) hemolitically active and extremely toxic in vivo. Recent ...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章

    doi:10.3389/fimmu.2020.507092

    authors: Vita GM,De Simone G,Leboffe L,Montagnani F,Mariotti D,Di Bella S,Luzzati R,Gori A,Ascenzi P,di Masi A

    更新日期:2020-12-08 00:00:00

  • Damage-Associated Molecular Patterns in Myocardial Infarction and Heart Transplantation: The Road to Translational Success.

    abstract::In the setting of myocardial infarction (MI), ischemia reperfusion injury (IRI) occurs due to occlusion (ischemia) and subsequent re-establishment of blood flow (reperfusion) of a coronary artery. A similar phenomenon is observed in heart transplantation (HTx) when, after cold storage, the donor heart is connected to ...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章,评审

    doi:10.3389/fimmu.2020.599511

    authors: Silvis MJM,Kaffka Genaamd Dengler SE,Odille CA,Mishra M,van der Kaaij NP,Doevendans PA,Sluijter JPG,de Kleijn DPV,de Jager SCA,Bosch L,van Hout GPJ

    更新日期:2020-12-08 00:00:00

  • Molecular and Immune Characteristics for Lung Adenocarcinoma Patients With ERLIN2 Overexpression.

    abstract:Background:Endoplasmic reticulum lipid raft-associated protein 2 (ERLIN2) is protein contained in the membrane of the endoplasmic reticulum. In lung adenocarcinoma (LUAD), the molecular function of ERLIN2 and the correlation between ERLIN2 and tumor-infiltrating immune cells have been unclear. The aim of our study was ...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章

    doi:10.3389/fimmu.2020.568440

    authors: Liu Y,Xie P,Jiang D,Liu J,Zhang J,Bian T,Shi J

    更新日期:2020-12-07 00:00:00

  • Differential Apoptotic Responses of Hemocyte Subpopulations to White Spot Syndrome Virus Infection in Fenneropenaeus chinensis.

    abstract::The apoptosis of hemocytes plays an essential function in shrimp immune defense against pathogen invasions. In order to further elucidate the differential apoptotic responses of the granulocytes and the hyalinocytes in Fenneropenaeus chinensis post WSSV infection, the characteristics of apoptotic dynamics and viral pr...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章

    doi:10.3389/fimmu.2020.594390

    authors: Cui C,Liang Q,Tang X,Xing J,Sheng X,Zhan W

    更新日期:2020-12-07 00:00:00

  • Broad Neutralization Responses Against Oncogenic Human Papillomaviruses Induced by a Minor Capsid L2 Polytope Genetically Incorporated Into Bacterial Ferritin Nanoparticles.

    abstract::Cervical cancer remains a global health burden despite the introduction of highly effective vaccines for the prophylaxis of causative human papillomavirus infection (HPV). Current efforts to eradicate cervical cancer focus on the development of broadly protective, cost-effective approaches. HPV minor capsid protein L2...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章

    doi:10.3389/fimmu.2020.606569

    authors: Yang F,Mariz FC,Zhao X,Spagnoli G,Ottonello S,Müller M

    更新日期:2020-12-04 00:00:00

  • Angiogenesis in Lymph Nodes Is a Critical Regulator of Immune Response and Lymphoma Growth.

    abstract::Tumor-induced remodeling of the microenvironment in lymph nodes (LNs) includes the formation of blood vessels, which goes beyond the regulation of metabolism, and shaping a survival niche for tumor cells. In contrast to solid tumors, which primarily rely on neo-angiogenesis, hematopoietic malignancies usually grow wit...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章,评审

    doi:10.3389/fimmu.2020.591741

    authors: Menzel L,Höpken UE,Rehm A

    更新日期:2020-12-03 00:00:00

  • Tumor-Associated Neutrophils and Macrophages-Heterogenous but Not Chaotic.

    abstract::Tumor-associated macrophages (TAMs) and tumor-associated neutrophils (TANs) have been extensively studied. Their pleotropic roles were observed in multiple steps of tumor progression and metastasis, and sometimes appeared to be inconsistent across different studies. In this review, we collectively discussed many lines...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章,评审

    doi:10.3389/fimmu.2020.553967

    authors: Wu L,Zhang XH

    更新日期:2020-12-02 00:00:00

  • Metabolic Vulnerabilities and Epigenetic Dysregulation in Myeloproliferative Neoplasms.

    abstract::The Janus kinase 2 (JAK2)-driven myeloproliferative neoplasms (MPNs) are associated with clonal myelopoiesis, elevated risk of death due to thrombotic complications, and transformation to acute myeloid leukemia (AML). JAK2 inhibitors improve the quality of life for MPN patients, but these approved therapeutics do not ...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章

    doi:10.3389/fimmu.2020.604142

    authors: Sharma V,Wright KL,Epling-Burnette PK,Reuther GW

    更新日期:2020-11-30 00:00:00

  • The Intestinal Microbiota and Colorectal Cancer.

    abstract::The intestinal microbiota, composed of a large population of microorganisms, is often considered a "forgotten organ" in human health and diseases. Increasing evidence indicates that dysbiosis of the intestinal microbiota is closely related to colorectal cancer (CRC). The roles for intestinal microorganisms that initia...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章,评审

    doi:10.3389/fimmu.2020.615056

    authors: Cheng Y,Ling Z,Li L

    更新日期:2020-11-30 00:00:00

  • Targeting Interleukin-2-Inducible T-Cell Kinase (ITK) Differentiates GVL and GVHD in Allo-HSCT.

    abstract::Allogeneic hematopoietic stem cell transplantation is a potentially curative procedure for many malignant diseases. Donor T cells prevent disease recurrence via graft-versus-leukemia (GVL) effect. Donor T cells also contribute to graft-versus-host disease (GVHD), a debilitating and potentially fatal complication. Nove...

    journal_title:Frontiers in immunology

    pub_type: 杂志文章

    doi:10.3389/fimmu.2020.593863

    authors: Mammadli M,Huang W,Harris R,Sultana A,Cheng Y,Tong W,Pu J,Gentile T,Dsouza S,Yang Q,Bah A,August A,Karimi M

    更新日期:2020-11-26 00:00:00

1388 条记录 1/35 页 « 12345678...3435 »