解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Pseudorabies virus (PRV) belongs to the Alphaherpesvirinae subfamily of Herpesviridae. PRV-induced pseudorabies is a highly contagious disease that has caused huge economic losses to the global swine industry. The PRV gE/gI gene deletion vaccine strain (Fa ΔgE/gI strain) constructed from the PRV Fa wild-type strain wa...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-020-01760-6
更新日期:2020-08-01 00:00:00
abstract::Bovine viral diarrhea virus (BVDV) belongs to the Pestivirus genus of the Flaviviridae family and has worldwide distribution, being one of the main causes of economic losses in cattle raising. The genome of pestiviruses is a single strand of positive-sense RNA with a length of 12.3 kb, which encodes one open reading f...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-020-01756-2
更新日期:2020-08-01 00:00:00
abstract::Acinetobacter pittii is an important pathogen causing nosocomial infection worldwide. In this study, a multidrug-resistant A. pittii ABC38 was used as host bacterium to isolate the lytic phage vB_ApiP_XC38. The biological characteristics of vB_ApiP_XC38 were studied and the genome was sequenced and analyzed. vB_ApiP_X...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-020-01766-0
更新日期:2020-08-01 00:00:00
abstract::Novel duck reovirus (NDRV), the prototype strain of the species Avian orthoreovirus (ARV), is associated with high mortality in Pekin ducklings. σC is an outer capsid protein encoded by the S1 genome segment of NDRV which mediates attachment to host cells. Our previous studies using immunoprecipitation and mass spectr...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-020-01750-8
更新日期:2020-06-01 00:00:00
abstract::African monkeys are resistant to HIV-1 infection due to intrinsic restriction mechanisms found in their cells. However, although they can be infected by monkey-adapted modified HIV-1 particles that are designed to overcome known restriction factors, virus numbers drop to undetectable levels in immunocompetent animals....
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-020-01731-x
更新日期:2020-04-01 00:00:00
abstract::The exo-xis region of lambdoid phages contains open reading frames and genes that appear to be evolutionarily important. However, this region has received little attention up to now. In this study, we provided evidence that ea22, the largest gene of this region, favors the lysogenic pathway over the lytic pathway in c...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-020-01734-8
更新日期:2020-04-01 00:00:00
abstract::The emerging occurrence of antibiotic-resistant bacterial pathogens leads to a recollection of bacteriophage as antimicrobial therapeutics. This article presents a short overview of the clinical phage application including their use in military medicine and discusses the genotypic and phenotypic properties of a potent...
journal_title:Virus genes
pub_type: 杂志文章,评审
doi:10.1007/s11262-020-01735-7
更新日期:2020-04-01 00:00:00
abstract::Human parainfluenza virus type 3 (HPIV3) causes the majority of childhood viral pneumonia around the world. Fusing the viral and target cell membranes is crucial for its entry into target cells, and the fusion process requires the concerted actions of two viral glycoproteins: hemagglutinin-neuraminidase (HN) and fusio...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-019-01713-8
更新日期:2020-02-01 00:00:00
abstract::Canine distemper virus (CDV) causes a highly contagious disease in a wide range of carnivores. The hemagglutinin (H) protein of viruses shows the highest variability and plays an important role in modulation of viral antigenicity, virulence, and receptor recognition. Since 2012, canine distemper (CD) outbreaks in fur-...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-019-01720-9
更新日期:2020-02-01 00:00:00
abstract::The original version of this article unfortunately contained an error in the length of AIMV genome sequence. ...
journal_title:Virus genes
pub_type: 杂志文章,已发布勘误
doi:10.1007/s11262-019-01717-4
更新日期:2020-02-01 00:00:00
abstract::Bats are carriers of potentially zoonotic viruses, therefore it is crucial to identify viruses currently found in bats to better understand how they are maintained in bat populations and evaluate risks for transmission to other species. Adenoviruses have been previously detected in bats throughout the world, but sampl...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-019-01719-2
更新日期:2020-02-01 00:00:00
abstract::The establishment of viral pathogens in new host environments following spillover events probably requires adaptive changes within both the new host and pathogen. After many generations, signals for ancient cross-species transmission may become lost and a strictly host-adapted phylogeny may mimic true co-divergence wh...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-019-01702-x
更新日期:2019-12-01 00:00:00
abstract::Astroviruses (AstV) are associated with enteric and systemic disease in mammals and birds. Astroviruses have received increased attention recently as they have been found to be associated with sporadic neurologic disease in mammals including humans. In pigs, porcine astrovirus (PoAstV) can be widely detected and has b...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-019-01692-w
更新日期:2019-10-01 00:00:00
abstract::Orf virus (ORFV), a typical member of the Parapoxvirus genus within the family Poxviridae, which is the causative agent of Orf, a common epitheliotropic viral disease of sheep, goats, wild ruminants, and humans. In the present study, we sequenced the complete genomic sequences of two ORFV strains (ORFV-SY17, isolated ...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-019-01666-y
更新日期:2019-08-01 00:00:00
abstract::Typically associated with fungal species, members of the viral family Totiviridae have recently been shown to be associated with plants, including important crop species, such as Carica papaya (papaya) and Zea mays (maize). Maize-associated totivirus (MATV) was first described in China and more recently in Ecuador, wh...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-019-01650-6
更新日期:2019-06-01 00:00:00
abstract::The red imported fire ant (Solenopsis invicta) escaped its natural enemies when it was introduced into North America in the 1930s from South America. US efforts have focused on discovery of natural enemies, like viruses, to provide sustainable control of the ant. Nine new virus genomes were sequenced from the invasive...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-019-01652-4
更新日期:2019-06-01 00:00:00
abstract::The original version of this article unfortunately contained errors in the "Results" section. ...
journal_title:Virus genes
pub_type: 已发布勘误
doi:10.1007/s11262-019-01662-2
更新日期:2019-06-01 00:00:00
abstract::A maximum clade credibility tree constructed using the full-length spike (S) and hemagglutinin-esterase genes revealed that Vietnamese Bovine coronavirus (BCoV) strains belong to a single cluster (C1); therefore, they might share a common origin with Cuban and Chinese BCoV strains. The omega values of cluster 1 (C1) a...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-019-01647-1
更新日期:2019-06-01 00:00:00
abstract::Porcine pegiviruses (PPgV) have been first discovered in serum samples from domestic pigs in Germany in 2016 and then in the USA in 2018. To date, there is no documentation with respect to the presence of PPgVs in domestic pigs in China. Herein, we attempted to determine the presence and prevalence of PPgV in China an...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-018-1624-6
更新日期:2019-04-01 00:00:00
abstract::Schmallenberg virus (SBV) is the member of Peribunyaviridae family, which comprises pathogens of importance for human and veterinary medicine. The virus is transmitted only between animals and mainly by biting midges of the genus Culicoides. This study was performed in order to determine SBV genetic diversity and eluc...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-018-1607-7
更新日期:2018-12-01 00:00:00
abstract::Cotton leaf curl disease (CLCuD) has been a major constraint to cotton production across Pakistan and northwestern India since the early 1990s. The disease is caused by a number of begomoviruses, including Cotton leaf curl Multan virus (CLCuMuV), which associate with a specific host range and symptom determining betas...
journal_title:Virus genes
pub_type: 信件
doi:10.1007/s11262-018-1605-9
更新日期:2018-12-01 00:00:00
abstract::Two virus strains, tentatively designated as ON-6/P/05 and ON-7/E/05, were isolated from blood samples of healthy cattle in the Yaeyama Islands, located in the southwestern-most region of Japan, in 2005. Ultrastructural observations of infected baby hamster (BHK-21) cells revealed that the viruses had features consist...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-018-1592-x
更新日期:2018-10-01 00:00:00
abstract::We report here the complete genome sequence of a bipartite virus, herein denoted WLPRV/human/BRA/TO-34/201, from a sample collected in 2015 from a two-year-old child in Brazil presenting acute gastroenteritis. The virus has 98-99% identity (segments 2 and 1, respectively) with the Wuhan large pig roundworm virus (uncl...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-018-1557-0
更新日期:2018-06-01 00:00:00
abstract::During October 2014, unfamiliar mild mosaic and mottling symptoms were identified on leaves of pepper (Capsicum chinense cv. Habanero) seedlings grown in the Arava valley in Israel 2-3 weeks post planting. Symptomatic plants were tested positive by ELISA using laboratory-produced antisera for tobamovirus species. Typi...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-018-1539-2
更新日期:2018-04-01 00:00:00
abstract::Serum samples collected from 88 Peruvians with unexplained fever were analyzed for viral sequences using metagenomics. Nucleic acids of anelloviruses, pegivirus A (GBV-C), HIV, Dengue virus, and Oropouche virus were detected. We also characterized from two sera the RNA genomes of new species of partitivirus and dicist...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-017-1514-3
更新日期:2018-02-01 00:00:00
abstract::The spontaneous host-range mutants 812F1 and K1/420 are derived from polyvalent phage 812 that is almost identical to phage K, belonging to family Myoviridae and genus Kayvirus. Phage K1/420 is used for the phage therapy of staphylococcal infections. Endolysin of these mutants designated LysF1, consisting of an N-term...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-017-1507-2
更新日期:2018-02-01 00:00:00
abstract::Dengue virus (DENV) is an arthropod-borne human pathogen that represents a severe public health threat in both endemic and non-endemic regions. So far, there is no licensed vaccine or specific drugs available for dengue fever. A fifteen-amino-acid-long peptide that includes the NGR motif was chemically synthesized and...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-017-1508-1
更新日期:2018-02-01 00:00:00
abstract::Porcine stool-associated RNA virus 1 (Posavirus 1) is a novel member of picornaviruses and first identified from fecal samples of 30-day-old pigs with diarrhea in USA in 2011. To evaluate the existence of Posavirus 1 in swine herds, 118 clinical samples from diarrheal pigs and 31 fecal swabs from healthy pigs were col...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-017-1512-5
更新日期:2018-02-01 00:00:00
abstract::Recently, NADC30-like porcine reproductive and respiratory syndrome viruses (PRRSVs), which are genetically similar to the NADC30 strain isolated in the United States of America in 2008, have become prevalent in China. Here, a novel variant PRRSV strain named HNhx was successfully isolated on porcine alveolar macropha...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-017-1516-1
更新日期:2018-02-01 00:00:00
abstract::The foot-and-mouth disease virus (FMDV) nonstructural protein 3A plays an important role in viral replication, virulence, and host range. It has been shown that deletions of 10 or 19-20 amino acids in the C-terminal half of 3A attenuate serotype O and C FMDVs, which replicate poorly in bovine cells but normally in por...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-017-1480-9
更新日期:2017-12-01 00:00:00
abstract::We report the detection of rabbit haemorrhagic disease virus 2 (RHDV2) in the Madeira archipelago, Portugal. Viral circulation was confirmed by RT-qPCR and vp60 sequencing. Epidemiological data revealed the outbreak initiated in October 2016 in Porto Santo affecting wild and domestic rabbits. It was then detected thre...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-017-1483-6
更新日期:2017-12-01 00:00:00
abstract::Sapoviruses (SaVs) are enteric viruses and have been detected in various mammals. They are divided into multiple genogroups and genotypes based on the entire major capsid protein (VP1) encoding region sequences. In this study, we determined the first complete genome sequences of two genogroup V, genotype 3 (GV.3) SaV ...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-017-1481-8
更新日期:2017-12-01 00:00:00
abstract::Tumor-selectively replicating (oncolytic) viruses are promising tools for therapy of solid cancers and have been initially developed to achieve potent tumor lysis with acceptable side effects on healthy tissue. However, in recent years, oncolytic viruses have been recognized as therapeutic vehicles exhibiting multipro...
journal_title:Virus genes
pub_type: 杂志文章,评审
doi:10.1007/s11262-017-1488-1
更新日期:2017-10-01 00:00:00
abstract::Currently, virus-based vectors, namely derivatives of the adenovirus, are frequently used in a wide variety of ex vivo or local gene therapeutic applications. However, the efficacy of virus-based vectors in systemic applications is presently still extremely limited. Complex interactions of the various vector types wit...
journal_title:Virus genes
pub_type: 杂志文章,评审
doi:10.1007/s11262-017-1498-z
更新日期:2017-10-01 00:00:00
abstract::Emerging pseudorabies virus (PRV) variant has led to frequent outbreaks of PRV infection among Bartha-K61-vaccinated swine population in Chinese swine farms and caused high mortality in pigs of all age since late 2011. Here, we generated a gE/gI-deleted PRV (rPRVXJ-delgI/gE-EGFP) based on PRV variant strain (PRV-XJ) t...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-017-1454-y
更新日期:2017-08-01 00:00:00
abstract::Enterovirus 96 (EV-96) is a recently described member of the species Enterovirus C and is associated with paralysis and myelitis. In this study, using metagenomic sequencing, we identified a new enterovirus 96 strain (EV-96-SZ/GD/CHN/2014) as the sole pathogen causing hand, foot, and mouth disease (HFMD). A genomic co...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-017-1431-5
更新日期:2017-06-01 00:00:00
abstract::The Jumonji C-domain containing protein 6 (JMJD6) has had a convoluted history, and recent reports indicating a multifactorial role in foot-and-mouth disease virus (FMDV) infection have further complicated the functionality of this protein. It was first identified as the phosphatidylserine receptor on the cell surface...
journal_title:Virus genes
pub_type: 杂志文章,评审
doi:10.1007/s11262-017-1449-8
更新日期:2017-06-01 00:00:00
abstract::Proteins harbor domains or short linear motifs, which facilitate their functions and interactions. Finding functional motifs in protein sequences could predict the putative cellular roles or characteristics of hypothetical proteins. In this study, we present Shetti-Motif, which is an interactive tool to (i) map UniPro...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-016-1416-9
更新日期:2017-04-01 00:00:00
abstract::Recently, we reported that the frequency of hepatitis C virus (HCV) genotypes and subtypes has rapidly changed among intravenous drug users (IDUs) in Yunnan Province over the last 5 years; this is especially true for subtype 6a which has increased in frequency from 5 to 15%. Here, we assessed 120 HCV-positive plasma s...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-016-1420-0
更新日期:2017-04-01 00:00:00
abstract::A low-cost rodent model of HIV infection and which presents high application value is an effective tool to investigate HIV infection and pathogenesis. However, development of such a small animal model has been hampered by the unsuitability of rodent cells for HIV-1 replication given that the retrovirus HIV-1 has high ...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-016-1423-x
更新日期:2017-04-01 00:00:00