abstract：BACKGROUND:Malaria caused by Plasmodium falciparum in pregnancy can result in adverse maternal and fetal sequelae. This review evaluated the adherence of the national guidelines drawn from World Health Organization (WHO) regions, Africa, Eastern Mediterranean, Southeast Asia, and Western Pacific, to the WHO recommendat...

journal_title：Malaria journal

authors： Al Khaja KAJ,Sequeira RP

更新日期：2021-01-23 00:00:00

abstract：BACKGROUND:Rapid elimination of Plasmodium falciparum malaria in Cambodia is a goal with both national and international significance. Transmission of malaria in Cambodia is limited to forest environments, and the main population at risk consists of forest-goers who rely on forest products for income or sustenance. The...

journal_title：Malaria journal

authors： Kunkel A,Nguon C,Iv S,Chhim S,Peov D,Kong P,Kim S,Im S,Debackere M,Khim N,Popovici J,Srun S,Vantaux A,Guintran JO,Witkowski B,Piola P

更新日期：2021-01-20 00:00:00

abstract：BACKGROUND:The use of rapid diagnostic tests (RDTs) to diagnose malaria is common in sub-Saharan African laboratories, remote primary health facilities and in the community. Currently, there is a lack of reliable methods to ascertain health worker competency to accurately use RDTs in the testing and diagnosis of malari...

journal_title：Malaria journal

authors： Dorkenoo AM,Kouassi KC,Koura AK,Adams ML,Gbada K,Katawa G,Yakpa K,Charlebois R,Milgotina E,Merkel MO,Aidoo M

更新日期：2021-01-20 00:00:00

abstract：BACKGROUND:The Cascades region, Burkina Faso, has a high malaria burden despite reported high insecticide-treated mosquito net (ITN) use. Human and vector activities outside the hours when indoor interventions offer direct protection from infectious bites potentially increase exposure risk to bites from malaria-transmi...

journal_title：Malaria journal

authors： Guglielmo F,Sanou A,Churcher T,Ferguson HM,Ranson H,Sherrard-Smith E

更新日期：2021-01-18 00:00:00

abstract：BACKGROUND:Malaria remains highly endemic in Cameroon. The rapid emergence and spread of drug resistance was responsible for the change from monotherapies to artemisinin-based combinations. This systematic review and meta-analysis aimed to determine the prevalence and distribution of Plasmodium falciparum drug resistan...

journal_title：Malaria journal

authors： Niba PTN,Nji AM,Evehe MS,Ali IM,Netongo PM,Ngwafor R,Moyeh MN,Ngum LN,Ndum OE,Acho FA,Mbu'u CM,Fosah DA,Atogho-Tiedeu B,Achonduh-Atijegbe O,Djokam-Dadjeu R,Chedjou JPK,Bigoga JD,Moukoko CEE,Ajua A,Achidi E,Tallah

更新日期：2021-01-09 00:00:00

abstract：BACKGROUND:Advances in digitized video-tracking and behavioural analysis have enabled accurate recording and quantification of mosquito flight and host-seeking behaviours, facilitating development of individual (agent) based models at much finer spatial scales than previously possible. METHODS:Quantified behavioural p...

journal_title：Malaria journal

authors： Jones J,Murray GPD,McCall PJ

更新日期：2021-01-07 00:00:00

abstract：BACKGROUND:In endemic areas, children develop slowly and naturally anti-Plasmodium antibodies and become semi-immune. Seasonal Malaria Chemoprevention (SMC) with sulfadoxine-pyrimethamine + amodiaquine (SPAQ) is a new strategy to reduce malaria morbidity in West African young children. However, SMC may impact on the na...

journal_title：Malaria journal

authors： Mahaman Moustapha L,Adamou R,Ibrahim ML,Abdoulaye Louis Padounou M,Diallo A,Courtin D,Testa J,Ndiaye JLA

更新日期：2021-01-01 00:00:00

abstract：:The incidence and mortality of COVID-19, according to the World Health Organization reports, shows a noticeable difference between North America, Western Europe, and South Asia on one hand and most African countries on the other hand, especially the malaria-endemic countries. Although this observation could be attribu...

journal_title：Malaria journal

authors： Hussein MIH,Albashir AAD,Elawad OAMA,Homeida A

更新日期：2020-12-23 00:00:00

abstract：BACKGROUND:In clinical trials of therapy for uncomplicated Plasmodium falciparum, there are usually some patients who fail treatment even in the absence of drug resistance. Treatment failures, which can be due to recrudescence or re-infection, are categorized as 'clinical' or 'parasitological' failures, the former indi...

journal_title：Malaria journal

authors： Mumtaz R,Okell LC,Challenger JD

更新日期：2020-12-09 00:00:00

abstract：BACKGROUND:Understanding of malaria vector density, distribution, insecticide resistance, vector incrimination, infection status, and identification of sibling species are some of the essential components of vector control measures for achieving malaria elimination goals. METHODS:As part of the malaria elimination dem...

journal_title：Malaria journal

authors： Mishra AK,Bharti PK,Vishwakarma A,Nisar S,Rajvanshi H,Sharma RK,Saha KB,Shukla MM,Jayswar H,Das A,Kaur H,Wattal SL,Lal AA

更新日期：2020-12-02 00:00:00

abstract：BACKGROUND:Extensive genetic diversity in the Plasmodium falciparum circumsporozoite protein (PfCSP) is a major contributing factor to the moderate efficacy of the RTS,S/AS01 vaccine. The transmission intensity and rates of recombination within and between populations influence the extent of its genetic diversity. Unde...

journal_title：Malaria journal

authors： Amegashie EA,Amenga-Etego L,Adobor C,Ogoti P,Mbogo K,Amambua-Ngwa A,Ghansah A

更新日期：2020-11-27 00:00:00

abstract：BACKGROUND:Automated detection of malaria and dengue infection has been actively researched for more than two decades. Although many improvements have been achieved, these solutions remain too expensive for most laboratories and clinics in developing countries. The low range HORIBA Medical Haematology Analyzer, Yumizen...

journal_title：Malaria journal

authors： Dharap P,Raimbault S

更新日期：2020-11-23 00:00:00

abstract：BACKGROUND:Cerebral malaria (CM) is associated with morbidity and mortality despite the use of potent anti-malarial agents. Brain endothelial cell activation and dysfunction from oxidative and inflammatory host responses and products released by Plasmodium falciparum-infected erythrocytes (IE), are likely the major con...

journal_title：Malaria journal

authors： Mita-Mendoza NK,Magallon-Tejada A,Parmar P,Furtado R,Aldrich M,Saidi A,Taylor T,Smith J,Seydel K,Daily JP

更新日期：2020-10-21 00:00:00

abstract：BACKGROUND:Certain species of macaques are natural hosts of Plasmodium knowlesi and Plasmodium cynomolgi, which can both cause malaria in humans, and Plasmodium inui, which can be experimentally transmitted to humans. A significant number of zoonotic malaria cases have been reported in humans throughout Southeast Asia,...

journal_title：Malaria journal

authors： Fungfuang W,Udom C,Tongthainan D,Kadir KA,Singh B

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:In Togo, the National Malaria Control Programme, in collaboration with the Global Fund to Fight AIDS, Tuberculosis and Malaria, has implemented a pilot study for malaria sentinel surveillance since 2017, which consists of collecting information in real time and analysing this information for decision-making....

journal_title：Malaria journal

authors： Thomas A,Bakai TA,Atcha-Oubou T,Tchadjobo T,Voirin N

更新日期：2020-09-09 00:00:00

abstract：BACKGROUND:Long-lasting insecticidal nets (LLINs) are the primary malaria prevention and control intervention in many parts of sub-Saharan Africa. While LLINs are expected to last at least 3 years under normal use conditions, they can lose effectiveness because they fall out of use, are discarded, repurposed, physicall...

journal_title：Malaria journal

authors： Briet O,Koenker H,Norris L,Wiegand R,Vanden Eng J,Thackeray A,Williamson J,Gimnig JE,Fortes F,Akogbeto M,Yadouleton AW,Ombok M,Bayoh MN,Mzilahowa T,Abílio AP,Mabunda S,Cuamba N,Diouf E,Konaté L,Hamainza B,Katebe-S

更新日期：2020-08-28 00:00:00

abstract：BACKGROUND:Glucose-6-phosphate dehydrogenase (G6PD) deficiency is currently a threat to malaria elimination due to risk of primaquine-induced haemolysis in G6PD deficient individuals. The World Health Organization (WHO) recommends G6PD screening before providing primaquine as a radical treatment against vivax malaria. ...

journal_title：Malaria journal

authors： Marasini B,Lal BK,Thapa S,Awasthi KR,Bajracharya B,Khanal P,Neupane S,Jha SN,Acharya S,Iama S,Koirala M,Koirala D,Bhandari S,Mahato RK,Chaudhary A,Ghimire P,Magar RG,Bhattarai RK,Gornsawun G,Penpitchaporn P,Bancon

更新日期：2020-08-12 00:00:00

abstract：BACKGROUND:Malaria elimination efforts can be undermined by imported malaria infections. Imported infections are classified based on travel history. METHODS:A genetic strategy was applied to better understand the contribution of imported infections and to test for local transmission in the very low prevalence region o...

journal_title：Malaria journal

authors： Daniels RF,Schaffner SF,Dieye Y,Dieng G,Hainsworth M,Fall FB,Diouf CN,Ndiop M,Cisse M,Gueye AB,Sarr O,Guinot P,Deme AB,Bei AK,Sy M,Thwing J,MacInnis B,Earle D,Guinovart C,Sene D,Hartl DL,Ndiaye D,Steketee RW,

更新日期：2020-08-03 00:00:00

abstract：BACKGROUND:The production and use of malaria rapid diagnostic tests (RDTs) has risen dramatically over the past 20 years. In view of weak or non-existing in vitro diagnostics (IVD) regulations and post-marketing surveillance (PMS) systems in malaria endemic countries, the World Health Organization, later joined by the ...

journal_title：Malaria journal

authors： Incardona S,Bell D,Campillo A,Cunningham J,Ariey F,Fandeur T,Luchavez J,Luna CA,Ménard D,Nhem S,Sornillo JB,Witkowski B,Katz Z,Dittrich S,Ding XC

更新日期：2020-07-13 00:00:00

abstract：BACKGROUND:Marking mosquitoes is vital for mark-release-recapture and many laboratory studies, but their small size precludes the use of methods that are available for larger animals such as unique identifier tags and radio devices. Fluorescent dust is the most commonly used method to distinguish released individuals f...

journal_title：Malaria journal

authors： Aviles EI,Rotenberry RD,Collins CM,Dotson EM,Benedict MQ

更新日期：2020-07-06 00:00:00

abstract：BACKGROUND:Insecticide-treated nets (ITNs) and house modifications are proven vector control tools, yet in most regions, full coverage has not been achieved. This study investigates household factors associated with access to ITNs and house modification in Tanzania. METHODS:Baseline cross-sectional survey data from pr...

journal_title：Malaria journal

authors： Odufuwa OG,Ross A,Mlacha YP,Juma O,Mmbaga S,Msellemu D,Moore S

更新日期：2020-06-23 00:00:00

abstract：BACKGROUND:In rural south-eastern Tanzania, Anopheles funestus is a major malaria vector, and has been implicated in nearly 90% of all infective bites. Unfortunately, little is known about the natural ecological requirements and survival strategies of this mosquito species. METHODS:Potential mosquito aquatic habitats ...

journal_title：Malaria journal

authors： Nambunga IH,Ngowo HS,Mapua SA,Hape EE,Msugupakulya BJ,Msaky DS,Mhumbira NT,Mchwembo KR,Tamayamali GZ,Mlembe SV,Njalambaha RM,Lwetoijera DW,Finda MF,Govella NJ,Matoke-Muhia D,Kaindoa EW,Okumu FO

更新日期：2020-06-23 00:00:00

abstract：BACKGROUND:Developing thermostable vaccines is a challenge for pharmaceutical companies due to the inherent instability of biological molecules in aqueous solution. The problem is even more stringent in regions subjected to high temperatures in which protective cold chain is difficult to maintain due to a lack of infra...

journal_title：Malaria journal

authors： Fortpied J,Collignon S,Moniotte N,Renaud F,Bayat B,Lemoine D

更新日期：2020-06-08 00:00:00

abstract：BACKGROUND:Herbal medicine has been a rich source of new drugs exemplified by quinine and artemisinin. In this study, a variety of Japanese traditional herbal medicine ('Kampo') were examined for their potential anti-malarial activities. METHODS:A comprehensive screening methods were designed to identify novel anti-ma...

journal_title：Malaria journal

authors： Teklemichael AA,Mizukami S,Toume K,Mosaddeque F,Kamel MG,Kaneko O,Komatsu K,Karbwang J,Huy NT,Hirayama K

更新日期：2020-06-08 00:00:00

abstract：BACKGROUND:The Plasmodium falciparum chloroquine transporter gene (pfcrt) is known to be involved in chloroquine and amodiaquine resistance, and more particularly the mutations on the loci 72 to 76 localized within the second exon. Additionally, new mutations (T93S, H97Y, C101F, F145I, M343L, C350R and G353V) were rece...

journal_title：Malaria journal

authors： Foguim FT,Bogreau H,Gendrot M,Mosnier J,Fonta I,Benoit N,Amalvict R,Madamet M,Wein S,Pradines B,French National Reference Centre for Imported Malaria Study Group.

更新日期：2020-06-05 00:00:00

abstract：BACKGROUND:Rapid diagnostic tests (RDTs) have become the most common diagnostic tool for detection of Plasmodium falciparum malaria, in particular in remote areas. RDT blood spots provide a source of parasite DNA for molecular analysis. In this study, the utility of RDTs for molecular analysis and the performance of di...

journal_title：Malaria journal

authors： Srisutham S,Suwannasin K,Mathema VB,Sriprawat K,Smithuis FM,Nosten F,White NJ,Dondorp AM,Imwong M

更新日期：2020-05-27 00:00:00

abstract：BACKGROUND:While sub-microscopic malarial infections are frequent and potentially deleterious during pregnancy, routine molecular detection is still not feasible. This study aimed to assess the performance of a Histidine Rich Protein 2 (HRP2)-based ultrasensitive rapid diagnostic test (uRDT, Alere Malaria Ag Pf) for th...

journal_title：Malaria journal

authors： Briand V,Cottrell G,Tuike Ndam N,Martiáñez-Vendrell X,Vianou B,Mama A,Kouwaye B,Houzé S,Bailly J,Gbaguidi E,Sossou D,Massougbodji A,Accrombessi M,Mayor A,Ding XC,Fievet N

更新日期：2020-05-24 00:00:00

abstract：BACKGROUND:Long regarded as an epicenter of drug-resistant malaria, Southeast Asia continues to provide new challenges to the control of Plasmodium falciparum malaria. Recently, resistance to the artemisinin combination therapy partner drug piperaquine has been observed in multiple locations across Southeast Asia. Gene...

journal_title：Malaria journal

authors： Ansbro MR,Jacob CG,Amato R,Kekre M,Amaratunga C,Sreng S,Suon S,Miotto O,Fairhurst RM,Wellems TE,Kwiatkowski DP

更新日期：2020-05-13 00:00:00

abstract：BACKGROUND:Malaria in pregnancy is associated with considerable morbidity and mortality. Regular surveillance of artemisinin-based combination therapy tolerance, or molecular makers of resistance, is vital for effective malaria treatment, control and eradication programmes. Plasmodium falciparum multiple drug resistanc...

journal_title：Malaria journal

authors： Dossou-Yovo LR,Ntoumi F,Koukouikila-Koussounda F,Vouvoungui JC,Adedoja A,Nderu D,Velavan TP,Lenga A

更新日期：2020-05-08 00:00:00

abstract：BACKGROUND:Malaria continues to be a disease of massive burden in Africa, and the public health resources targeted at surveillance, prevention, control, and intervention comprise large outlays of expense. Malaria transmission is largely constrained by the suitability of the climate for Anopheles mosquitoes and Plasmodi...

journal_title：Malaria journal

authors： Ryan SJ,Lippi CA,Zermoglio F

更新日期：2020-05-01 00:00:00

abstract：:Most malaria-endemic countries have struggled in the past decade to establish effective national-scale continuous distribution mechanisms for long-lasting insecticidal nets (LLINs). Since the implementation of the Tanzania National Voucher Scheme in 2004 and mass-distribution campaigns in 2009-2011 and 2015-2016, Tanz...

journal_title：Malaria journal

authors： Yukich J,Stuck L,Scates S,Wisniewski J,Chacky F,Festo C,Kabulika G,Dimoso K,Mandike R,Greer G,Serbantez N,Elisaria E,Nyoni W,Dadi D,Akim I,Lengeler C,Brown N,Koenker H

更新日期：2020-04-17 00:00:00

abstract：BACKGROUND:KwaZulu-Natal, one of South Africa's three malaria endemic provinces, is nearing malaria elimination, reporting fewer than 100 locally-acquired cases annually since 2010. Despite sustained implementation of essential interventions, including annual indoor residual spraying, prompt case detection using malari...

journal_title：Malaria journal

authors： Raman J,Gast L,Balawanth R,Tessema S,Brooke B,Maharaj R,Munhenga G,Tshikae P,Lakan V,Mwamba T,Makowa H,Sangweni L,Mkhabela M,Zondo N,Mohulatsi E,Nyawo Z,Ngxongo S,Msimang S,Dagata N,Greenhouse B,Birkholtz LM,Shi

更新日期：2020-04-15 00:00:00

abstract：BACKGROUND:A previous study reported that the malaria parasite Plasmodium falciparum enters an altered growth state upon extracellular withdrawal of the essential amino acid isoleucine. Parasites slowed transit through the cell cycle when deprived of isoleucine prior to the onset of S-phase. METHODS:This project was u...

journal_title：Malaria journal

authors： McLean KJ,Jacobs-Lorena M

更新日期：2020-04-08 00:00:00

abstract：BACKGROUND:Insecticide-treated nets (ITNs) are losing efficacy against pyrethroid-resistant malaria vector populations throughout Africa. Safeguarding bed net efficacy, vital for effective malaria control, requires greater knowledge of mosquito-ITN interactions and how this impacts on the mosquito. METHODS:A purpose-b...

journal_title：Malaria journal

authors： Hughes A,Foster GM,Guy A,Matope A,Abe M,Towers D,McCall PJ

更新日期：2020-04-07 00:00:00

abstract：BACKGROUND:There is an urgent need for an effective vaccine to control and eradicate malaria, one of the most serious global infectious diseases. Plasmodium merozoite surface protein 4 (MSP4) has been listed as a blood-stage subunit vaccine candidate for malaria. Infection with Plasmodium ovale species including P. ova...

journal_title：Malaria journal

authors： Uwase J,Chu R,Kassegne K,Lei Y,Shen F,Fu H,Sun Y,Xuan Y,Cao J,Cheng Y

更新日期：2020-03-30 00:00:00

abstract：BACKGROUND:Residents of malaria-endemic communities spend several hours outdoors performing different activities, e.g. cooking, story-telling or eating, thereby exposing themselves to potentially-infectious mosquitoes. This compromises effectiveness of indoor interventions, notably long-lasting insecticide-treated nets...

journal_title：Malaria journal

authors： Masalu JP,Finda M,Killeen GF,Ngowo HS,Pinda PG,Okumu FO

更新日期：2020-03-10 00:00:00

abstract：BACKGROUND:In malaria-endemic areas, human populations are frequently exposed to immunomodulatory salivary components injected during mosquito blood feeding. The consequences on pathogen-specific immune responses are not well known. This study evaluated and compared the humoral responses specific to merozoite stage vac...

journal_title：Malaria journal

authors： Aka KG,Traoré DF,Sagna AB,Zoh DD,Assi SB,Tchiekoi BN,Adja AM,Remoue F,Poinsignon A

更新日期：2020-02-21 00:00:00

abstract：BACKGROUND:Passerine birds are frequently infected with diverse haemosporidian parasites. While infections are traditionally considered benign in wild birds, recent studies demonstrated mortalities of passerine species due to exo-erythrocytic development of the parasites, which can damage organs in affected hosts. Howe...

journal_title：Malaria journal

authors： Himmel T,Harl J,Pfanner S,Nedorost N,Nowotny N,Weissenböck H

更新日期：2020-02-12 00:00:00

abstract：BACKGROUND:Asymptomatic carriage of Plasmodium falciparum is widespread in adults and children living in malaria-endemic countries. This study identified the prevalence of malaria parasites and the corresponding levels of naturally acquired anti-parasite antibody levels in afebrile adults living in two communities in t...

journal_title：Malaria journal

authors： Acquah FK,Lo AC,Akyea-Mensah K,Abagna HB,Faye B,Theisen M,Gyan BA,Amoah LE

更新日期：2020-02-10 00:00:00

abstract：BACKGROUND:The epidemiological control of malaria has been hampered by the appearance of parasite resistance to anti-malarial drugs and by the resistance of mosquito vectors to control measures. This has also been associated with weak transmission control, mostly due to poor control of asymptomatic patients associated ...

journal_title：Malaria journal

authors： Ararat-Sarria M,Prado CC,Camargo M,Ospina LT,Camargo PA,Curtidor H,Patarroyo MA

更新日期：2020-02-03 00:00:00