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你正在浏览Current Diabetes Reports期刊下所有文献
  • Cardiometabolic Morbidity and Mortality with Smoking Cessation, Review of Recommendations for People with Diabetes and Obesity.

    abstract:PURPOSE OF REVIEW:Obesity is closely linked with the pathogenesis of type 2 diabetes (T2DM) and cardiovascular disease (CVD), and whilst smoking cessation is associated with weight gain, there are concerns that this weight gain may offset the benefit of CVD risk reduction especially in those with considerable post-cess...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-020-01352-6

    authors: Kos K

    更新日期:2020-12-08 00:00:00

  • Sodium-Glucose Cotransporter Type 2 (SGLT-2) Inhibitors and Ketogenesis: the Good and the Bad.

    abstract:PURPOSE OF REVIEW:The micro/macrovascular complications of diabetes cause considerable morbidity and premature mortality. The SGLT2 inhibitors are the first diabetes medications with significant benefits on microvascular disease (nephropathy) and macrovascular cardiovascular disease. In this review, we evaluate one of ...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-020-01359-z

    authors: Ekanayake P,Hupfeld C,Mudaliar S

    更新日期:2020-11-23 00:00:00

  • What Makes Sodium-Glucose Co-Transporter-2 Inhibitors Stand out in Heart Failure?

    abstract:PURPOSE OF REVIEW:We highlight the unique properties of the sodium-glucose cotransporter-2 (SGLT-2 inhibitors) which may lend favorably to their efficient integration in the background of other heart failure (HF) therapies. We also discuss the unique aspects of SGLT-2 inhibitor dosing, lack of titration needs, effects ...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-020-01347-3

    authors: Khan MS,Vaduganathan M

    更新日期:2020-10-11 00:00:00

  • Thyroid Hormone Signalling Alteration in Diabetic Nephropathy and Cardiomyopathy: a "Switch" to the Foetal Gene Programme.

    abstract:PURPOSE OF THE REVIEW:In this study, we will analyse how diabetes induces the reactivation of organs' developmental programmes and growth, discuss how thyroid hormone (TH) signalling orchestrates these processes, and suggest novel strategies for exploiting TH-mediated reparative and regenerative properties. RECENT FIN...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-020-01344-6

    authors: Mantzouratou P,Lavecchia AM,Novelli R,Xinaris C

    更新日期:2020-09-28 00:00:00

  • Bariatric Surgery for Monogenic Non-syndromic and Syndromic Obesity Disorders.

    abstract:PURPOSE OF REVIEW:The global prevalence of obesity has increased rapidly over the last decades, posing a severe threat to human health. Currently, bariatric surgery is the most effective therapy for patients with morbid obesity. It is unknown whether this treatment is also suitable for patients with obesity due to a co...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-020-01327-7

    authors: Vos N,Oussaada SM,Cooiman MI,Kleinendorst L,Ter Horst KW,Hazebroek EJ,Romijn JA,Serlie MJ,Mannens MMAM,van Haelst MM

    更新日期:2020-07-30 00:00:00

  • Role of Senescent Renal Cells in Pathophysiology of Diabetic Kidney Disease.

    abstract:PURPOSE OF REVIEW:Diabetic kidney disease (DKD) is the leading cause of kidney failure in the USA, representing ~ 44% of all cases of kidney failure. Advancements in both glucose management and inhibitors of the renin-angiotensin system have significantly improved prognosis for individuals with DKD, yet DKD continues t...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-020-01314-y

    authors: Wiley CD

    更新日期:2020-06-16 00:00:00

  • CNS Regulation of Glucose Homeostasis: Role of the Leptin-Melanocortin System.

    abstract:PURPOSE OF REVIEW:In this brief review, we highlight studies that have contributed to our current understanding of glucose homeostasis by the central nervous system (CNS) leptin-melanocortin system, particularly proopiomelanocortin neurons and melanocortin-4 receptors (MC4R). RECENT FINDINGS:Leptin deficiency is assoc...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-020-01311-1

    authors: da Silva AA,do Carmo JM,Hall JE

    更新日期:2020-05-26 00:00:00

  • Euglycemic Ketoacidosis.

    abstract:PURPOSE OF REVIEW:Diabetic ketoacidosis is a life-threatening complication of diabetes characterized by hyperglycemia, acidosis, and ketosis. Ketoacidosis may occur with blood glucose level < 200 mg/dl (improperly defined as euglycemic ketoacidosis, euKA) and also in people without diabetes. The absence of marked hyper...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-020-01307-x

    authors: Bonora BM,Avogaro A,Fadini GP

    更新日期:2020-05-19 00:00:00

  • Evidence and Challenges for Translation and Population Impact of the Diabetes Prevention Program.

    abstract:PURPOSE OF REVIEW:Type 2 diabetes is common, burdensome, and preventable. Landmark trials such as the Diabetes Prevention Program (DPP) demonstrated that resource-intensive lifestyle support interventions resulting in modest weight loss via healthy diet changes and physical activity can lower the rate of diabetes devel...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-020-1293-4

    authors: Ackermann RT,O'Brien MJ

    更新日期:2020-02-20 00:00:00

  • Heterogeneity in Obesity: Genetic Basis and Metabolic Consequences.

    abstract:PURPOSE OF REVIEW:Our review provides a brief summary of the most recent advances towards the identification of the genetic basis of specific aspects of obesity and the quantification of their consequences on health. We also highlight the most promising avenues to be explored in the future. RECENT FINDINGS:While obesi...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-020-1285-4

    authors: Sulc J,Winkler TW,Heid IM,Kutalik Z

    更新日期:2020-01-22 00:00:00

  • Technological Advancements in the Management of Type 2 Diabetes.

    abstract:PURPOSE OF REVIEW:The increasing prevalence of type 2 diabetes is driving the boundaries of clinical diabetes care outside of the traditional office setting. The purpose of this paper will be to review recent technological advances in the medical management of people with type 2 diabetes, spanning the spectrum of care ...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-019-1278-3

    authors: Grant AK,Golden L

    更新日期:2019-12-20 00:00:00

  • The Use of Non-insulin Agents in Gestational Diabetes: Clinical Considerations in Tailoring Therapy.

    abstract:PURPOSE OF REVIEW:To assess evidence to date for use of non-insulin agents in treatment of gestational diabetes mellitus. RECENT FINDINGS:There has been increasing interest in the use of non-insulin agents, primarily metformin and glyburide (which both cross the placenta). Metformin has been associated with less mater...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-019-1243-1

    authors: Blair RA,Rosenberg EA,Palermo NE

    更新日期:2019-12-06 00:00:00

  • Diagnostic Strategies for Gestational Diabetes Mellitus: Review of Current Evidence.

    abstract:PURPOSE OF REVIEW:Currently, the diagnosis of gestational diabetes mellitus (GDM) lacks uniformity. Several controversies are still under debate, especially on the method of screening and diagnosis. This review focuses on recent literature and provides current evidence for the screening and diagnosis of GDM. RECENT FI...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-019-1271-x

    authors: Kuo CH,Li HY

    更新日期:2019-12-04 00:00:00

  • Brain Stimulation to Modulate Food Intake and Eating Behavior.

    abstract:PURPOSE OF REVIEW:Appetitive behaviors are mediated through homeostatic and reward signaling of brain circuits. There has been increasing interest in the use of neuromodulation techniques aimed at targeting brain regions such as the lateral prefrontal and subcortical regions associated with dysregulation of eating beha...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-019-1250-2

    authors: Dendy R,Stinson EJ,Guerithault N,Gluck ME

    更新日期:2019-12-02 00:00:00

  • Updates in Glycemic Management in the Hospital.

    abstract:PURPOSE OF REVIEW:To provide an update of glycemic management during metabolic stress related to surgery or critical illness. RECENT FINDINGS:There is a clear association between severe hyperglycemia, hypoglycemia, and high glycemic variability and poor outcomes of postoperative or critically ill patients. However, th...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-019-1274-7

    authors: Mongkolpun W,Provenzano B,Preiser JC

    更新日期:2019-11-20 00:00:00

  • Diabetes and Disasters: Recent Studies and Resources for Preparedness.

    abstract:PURPOSE OF REVIEW:Studies have shown that disasters may exacerbate the comorbidities in vulnerable populations such as those with a pre-existing chronic medical condition like diabetes. This article highlights recent studies that look at the impact of disasters on people with diabetes and also shows recent resources fo...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-019-1258-7

    authors: Allweiss P

    更新日期:2019-11-20 00:00:00

  • Financing Diabetes Care in the U.S. Health System: Payment Innovations for Addressing the Medical and Social Determinants of Health.

    abstract:PURPOSE OF REVIEW:Review innovations in health care financing promoting health system investments in addressing medical and social determinants of health (SDH) for patients with diabetes. RECENT FINDINGS:Particular payment models implemented in the public and private sectors increasingly offer flexibility in health ca...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-019-1275-6

    authors: Saulsberry L,Peek M

    更新日期:2019-11-20 00:00:00

  • Benefit-to-Risk Balance of Weight Loss Interventions in Older Adults with Obesity.

    abstract:PURPOSE OF REVIEW:Obesity in the older adult is a burgeoning health epidemic that leads to increased morbidity, disability, and institutionalization. This review presents a brief overview of geriatric-specific consequences of obesity by highlighting the risks and benefits of intentional weight loss. RECENT FINDINGS:In...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-019-1249-8

    authors: DiMilia PR,Mittman AC,Batsis JA

    更新日期:2019-11-04 00:00:00

  • The Genetic Contribution to Type 1 Diabetes.

    abstract:PURPOSE OF REVIEW:To provide an updated summary of discoveries made to date resulting from genome-wide association study (GWAS) and sequencing studies, and to discuss the latest loci added to the growing repertoire of genetic signals predisposing to type 1 diabetes (T1D). RECENT FINDINGS:Genetic studies have identifie...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-019-1235-1

    authors: Bakay M,Pandey R,Grant SFA,Hakonarson H

    更新日期:2019-11-04 00:00:00

  • Emerging Insights and Interventions for Diabetic Retinopathy.

    abstract:PURPOSE OF REVIEW:To introduce recent advances in the understanding of diabetic retinopathy and to summarize current and emerging strategies to treat this common and complex cause of vision loss. RECENT FINDINGS:Advances in retinal imaging and functional analysis indicate that retinal vascular and neural pathologies e...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-019-1218-2

    authors: Honasoge A,Nudleman E,Smith M,Rajagopal R

    更新日期:2019-09-10 00:00:00

  • Predictive Mathematical Models of Weight Loss.

    abstract:PURPOSE OF REVIEW:Validated thermodynamic energy balance models that predict weight change are ever more in use today. Delivery of model predictions using web-based applets and/or smart phones has transformed these models into viable clinical tools. Here, we provide the general framework for thermodynamic energy balanc...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-019-1207-5

    authors: Thomas DM,Scioletti M,Heymsfield SB

    更新日期:2019-08-31 00:00:00

  • Medical Devices in Obesity Treatment.

    abstract:PURPOSE OF REVIEW:Obesity is increasing at an alarming rate and now poses a global threat to humankind. In recent years, we have seen the emergence of medical devices to combat the obesity epidemic. These therapeutic strategies are discussed in this review dividing them into gastric and duodenal therapies. RECENT FIND...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-019-1217-3

    authors: Ruban A,Doshi A,Lam E,Teare JP

    更新日期:2019-08-30 00:00:00

  • Genetic and Environmental Interaction in Type 1 Diabetes: a Relationship Between Genetic Risk Alleles and Molecular Traits of Enterovirus Infection?

    abstract:PURPOSE OF REVIEW:We provide an overview of the current knowledge regarding the natural history of human type 1 diabetes (T1D) and the documented associations between virus infections (in particular the enteroviruses) and disease development. We review studies that examine whether T1D-specific risk alleles in genes inv...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-019-1192-8

    authors: Blanter M,Sork H,Tuomela S,Flodström-Tullberg M

    更新日期:2019-08-10 00:00:00

  • Developmental Programming of Body Composition: Update on Evidence and Mechanisms.

    abstract:PURPOSE OF REVIEW:A growing body of epidemiological and experimental data indicate that nutritional or environmental stressors during early development can induce long-term adaptations that increase risk of obesity, diabetes, cardiovascular disease, and other chronic conditions-a phenomenon termed "developmental progra...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-019-1170-1

    authors: Isganaitis E

    更新日期:2019-07-20 00:00:00

  • Air Pollution, Oxidative Stress, and Diabetes: a Life Course Epidemiologic Perspective.

    abstract:PURPOSE OF REVIEW:Ambient air pollution is strongly linked to cardiovascular and respiratory diseases. We summarize available published evidence regarding similar associations with diabetes across the life course. RECENT FINDINGS:We performed a life-course survey of the recent literature, including prenatal, gestation...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-019-1181-y

    authors: Lim CC,Thurston GD

    更新日期:2019-07-19 00:00:00

  • Machine Perfusion and the Pancreas: Will It Increase the Donor Pool?

    abstract:PURPOSE OF REVIEW:Pancreas transplantation enables complete patient independence from exogenous insulin administration and increases both patient survival and quality of life. Despite this, there has been a decline in pancreas transplantation for the past 20 years, influenced by changing donor demographics with more hi...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-019-1165-y

    authors: Hamaoui K,Papalois V

    更新日期:2019-07-10 00:00:00

  • Bioprinting an Artificial Pancreas for Type 1 Diabetes.

    abstract:PURPOSE OF REVIEW:Pancreatic islet cell transplantation is currently the only curative cell therapy for type 1 diabetes mellitus. However, its potential to treat many more patients is limited by several challenges. The emergence of 3D bioprinting technology from recent advances in 3D printing, biomaterials, and cell bi...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-019-1166-x

    authors: Kim J,Kang K,Drogemuller CJ,Wallace GG,Coates PT

    更新日期:2019-07-04 00:00:00

  • Updates in Gestational Diabetes Prevalence, Treatment, and Health Policy.

    abstract:PURPOSE OF REVIEW:Gestational diabetes (GDM) is associated with adverse pregnancy and neonatal outcomes and increased maternal risk for subsequent type 2 diabetes. The best diagnostic strategy for GDM is debated and the role of oral antidiabetic medications (OAD) for treatment is unclear. In this paper, we review metho...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-019-1147-0

    authors: Dickens LT,Thomas CC

    更新日期:2019-05-09 00:00:00

  • The Contribution of Low-Frequency and Rare Coding Variation to Susceptibility to Type 2 Diabetes.

    abstract:PURPOSE OF REVIEW:Soon after the first genome-wide association study (GWAS) for type 2 diabetes (T2D) was published, it was hypothesized that rare and low-frequency variants might explain a substantial proportion of disease risk. Rare coding variants in particular were emphasized given their large expected role in dise...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-019-1142-5

    authors: Flannick J

    更新日期:2019-04-08 00:00:00

  • Genetic Mechanisms Highlight Shared Pathways for the Pathogenesis of Polygenic Type 1 Diabetes and Monogenic Autoimmune Diabetes.

    abstract:PURPOSE OF REVIEW:To highlight pathways important for the development of autoimmune diabetes by investigating shared mechanisms of disease in polygenic and monogenic diabetes. RECENT FINDINGS:Genome-wide association studies have identified 57 genetic risk loci for type 1 diabetes. Progress has been made in unravelling...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-019-1141-6

    authors: Johnson MB,Cerosaletti K,Flanagan SE,Buckner JH

    更新日期:2019-03-19 00:00:00

  • The Continuing Evolution of Precision Health in Type 2 Diabetes: Achievements and Challenges.

    abstract:PURPOSE OF REVIEW:The purpose of this review was to summarize recent advances in the genomics of type 2 diabetes (T2D) and to highlight current initiatives to advance precision health. RECENT FINDINGS:Generation of multi-omic data to measure each of the "biologic layers," developments in describing genomic function an...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-019-1137-2

    authors: Lin Y,Wessel J

    更新日期:2019-02-26 00:00:00

  • The Evolving Role of the Cardiologist in the Management of Type 2 Diabetes.

    abstract:PURPOSE OF REVIEW:To evaluate the treatment of type 2 diabetes from a cardiologist's view. RECENT FINDINGS:A new era in the treatment of type 2 diabetes began for the cardiologist in 2015 with the publication of the EMPA-REG outcome trial finding a significant reduction in CV death with empagliflozin (oral sodium-gluc...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-018-1114-1

    authors: Chilton RJ,Gallegos KM,Silva-Cardoso J,Oliveros R,Pham S

    更新日期:2018-11-08 00:00:00

  • Gut Microbiome in Obesity, Metabolic Syndrome, and Diabetes.

    abstract:PURPOSE OF REVIEW:Obesity and diabetes are worldwide epidemics. There is also a growing body of evidence relating the gut microbiome composition to insulin resistance. The purpose of this review is to delineate the studies linking gut microbiota to obesity, metabolic syndrome, and diabetes. RECENT FINDINGS:Animal stud...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-018-1104-3

    authors: Chen X,Devaraj S

    更新日期:2018-10-18 00:00:00

  • Epigenetics Variation and Pathogenesis in Diabetes.

    abstract:PURPOSE OF REVIEW:Great strides have recently been made in elucidating the role of genetic sequence variation in diabetes pathogenesis. Increasingly, studies are focusing on other factors that may contribute to the pathogenesis of diabetes, such as epigenetics, a term "traditionally" encompassing changes to the DNA tha...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-018-1091-4

    authors: Zhang H,Pollin TI

    更新日期:2018-10-02 00:00:00

  • Oral Agents for the Treatment of Gestational Diabetes.

    abstract:PURPOSE OF REVIEW:To review the current evidence of the safety and efficacy of the use of oral agents for treatment of gestational diabetes (GDM). RECENT FINDINGS:The use of metformin and glyburide in pregnancy for treatment of GDM has dramatically increased since the early 2000s. Meta-analyses suggest that glyburide ...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-018-1093-2

    authors: Finneran MM,Landon MB

    更新日期:2018-09-28 00:00:00

  • Building Toward a Population-Based Approach to Diabetes Screening and Prevention for US Adults.

    abstract:PURPOSE OF REVIEW:Evidence-based treatments for prediabetes can prevent and delay the development of type 2 diabetes in adults. In this review, we propose a framework for population-based diabetes prevention that links screening and prevention activities across key stakeholders. We also discuss gaps in current practice...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-018-1090-5

    authors: Bowen ME,Schmittdiel JA,Kullgren JT,Ackermann RT,O'Brien MJ

    更新日期:2018-09-19 00:00:00

  • Advancing Measurement of Diabetes at the Population Level.

    abstract:PURPOSE:The measurement and estimation of diabetes in populations guides resource allocation, health priorities, and can influence practice and future research. To provide a critical reflection on current diabetes surveillance, we provide in-depth discussion about how upstream determinants, prevalence, incidence, and d...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-018-1088-z

    authors: Ali MK,Siegel KR,Laxy M,Gregg EW

    更新日期:2018-09-19 00:00:00

  • Practical Tips for Implementing the Diabetes Prevention Program in Clinical Practice.

    abstract:PURPOSE OF REVIEW:The Diabetes Prevention Program (DPP) is an evidence-based lifestyle change program for prediabetes that is associated with a 58% reduction in 3-year diabetes incidence, and it has been supported by the American Medical Association and the Centers for Disease Control and Prevention. However, 9 in 10 p...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-018-1034-0

    authors: Jasik CB,Joy E,Brunisholz KD,Kirley K

    更新日期:2018-08-08 00:00:00

  • Methods for Measuring Risk for Type 2 Diabetes in Youth: the Oral Glucose Tolerance Test (OGTT).

    abstract:PURPOSE OF REVIEW:The oral glucose tolerance test (OGTT) is used both in clinical practice and research to assess glucose tolerance. In addition, the OGTT is utilized for surrogate measures of insulin sensitivity and the insulin response to enteral glucose and has been widely applied in the evaluation of β-cell dysfunc...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-018-1023-3

    authors: Chen ME,Aguirre RS,Hannon TS

    更新日期:2018-06-16 00:00:00

  • Congenital Diabetes: Comprehensive Genetic Testing Allows for Improved Diagnosis and Treatment of Diabetes and Other Associated Features.

    abstract:PURPOSE OF REVIEW:The goal of this review is to provide updates on congenital (neonatal) diabetes from 2011 to present, with an emphasis on publications from 2015 to present. RECENT FINDINGS:There has been continued worldwide progress in uncovering the genetic causes of diabetes presenting within the first year of lif...

    journal_title:Current diabetes reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11892-018-1016-2

    authors: Letourneau LR,Greeley SAW

    更新日期:2018-06-13 00:00:00

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