听力与言语-语言病理学

行为科学

医学伦理学

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  • Management of primary sclerosing cholangitis and its complications: an algorithmic approach.

    abstract::Primary sclerosing cholangitis (PSC) is a rare cholestatic liver disease, characterized by multiple strictures and dilatations of the intra- and extrahepatic bile ducts, leading to progressive liver fibrosis, in 10-15% cholangiocarcinoma, and ultimately end-stage liver disease. The pathogenesis is poorly understood, b...

    journal_title:Hepatology international

    pub_type: 杂志文章,评审

    doi:10.1007/s12072-020-10118-x

    authors: Prokopič M,Beuers U

    更新日期:2020-12-30 00:00:00

  • Vitamin A levels reflect disease severity and portal hypertension in patients with cirrhosis.

    abstract:BACKGROUND AND AIMS:The liver plays a key role in the storage, metabolism and homeostasis of fat-soluble vitamins. We investigated the relation of Vitamin(Vit)A/D/E serum levels with severity of liver disease and portal hypertension (PHT). METHODS:VitA/D/E serum levels were assessed in 234 patients with advanced chron...

    journal_title:Hepatology international

    pub_type: 杂志文章

    doi:10.1007/s12072-020-10112-3

    authors: Simbrunner B,Semmler G,Stadlmann A,Scheiner B,Schwabl P,Paternostro R,Bucsics T,Bauer D,Eigenbauer E,Pinter M,Stättermayer AF,Quehenberger P,Marculescu R,Trauner M,Mandorfer M,Reiberger T

    更新日期:2020-12-01 00:00:00

  • Association of arterial stiffness with the histological severity of nonalcoholic fatty liver disease.

    abstract:BACKGROUND:Although arterial stiffness has been reported to be associated with nonalcoholic fatty liver disease (NAFLD), previous studies have relied only on noninvasive assessments for the diagnosis of NAFLD. This study attempted to investigate the association of arterial stiffness with the histological severity of NA...

    journal_title:Hepatology international

    pub_type: 杂志文章

    doi:10.1007/s12072-020-10108-z

    authors: Kim HL,Koo BK,Joo SK,Kim W

    更新日期:2020-12-01 00:00:00

  • Incidence, risk factors, and prognosis of abnormal liver biochemical tests in COVID-19 patients: a systematic review and meta-analysis.

    abstract:BACKGROUND AND AIMS:Coronavirus disease 2019 (COVID-19) pandemic is ongoing. Except for lung injury, it is possible that COVID-19 patients develop liver injury. Thus, we conducted a systematic review and meta-analysis to explore the incidence, risk factors, and prognosis of abnormal liver biochemical tests in COVID-19 ...

    journal_title:Hepatology international

    pub_type: 杂志文章,meta分析

    doi:10.1007/s12072-020-10074-6

    authors: Wu Y,Li H,Guo X,Yoshida EM,Mendez-Sanchez N,Levi Sandri GB,Teschke R,Romeiro FG,Shukla A,Qi X

    更新日期:2020-09-01 00:00:00

  • Viscoelastic test-based bleeding risk score reliably predicts coagulopathic bleeding in decompensated cirrhosis and ACLF patients.

    abstract:BACKGROUND AND AIMS:Coagulopathic bleeding risk prediction is challenging in decompensated cirrhosis (DC) by conventional assays. Viscoelastic tests (VETs) are likely to be more useful for assessing coagulation status in these patients. We investigated whether the VET (Sonoclot) parameters with fibrinogen could predict...

    journal_title:Hepatology international

    pub_type: 杂志文章

    doi:10.1007/s12072-020-10036-y

    authors: Bihari C,Patil A,Shasthry SM,Baweja S,Kumar G,Sarin SK

    更新日期:2020-07-01 00:00:00

  • The prevalence of occult HBV infection in immunized children with HBsAg-positive parents: a hospital-based analysis.

    abstract:BACKGROUND AND OBJECT:The risk of occult HBV infection (OBI) in children whose mothers are HBV carriers has received more widespread attention, but there were few reports to focus on the children with HBsAg-positive parents. In this study, we aimed to investigate the prevalence of OBI in immunized children with HBsAg-p...

    journal_title:Hepatology international

    pub_type: 杂志文章

    doi:10.1007/s12072-020-10055-9

    authors: Zhuge S,Ge C,Yang Y,Cui Y,Yue X,Zhang Z,Xu H,Huang A,Zhao Y

    更新日期:2020-07-01 00:00:00

  • Effect of hepatitis B surface antibody in patients with core antibody-positive liver transplantation: a systematic review and meta-analysis.

    abstract:BACKGROUND AND AIM:There is an increased awareness of de novo hepatitis B virus (HBV) infection (DNH) in hepatitis B surface antigen (HBsAg)-negative recipients receiving hepatitis B core antibody (HBcAb)-positive liver organ. Whether hepatitis B surface antibody (HBsAb) has positive result on preventing the occurrence...

    journal_title:Hepatology international

    pub_type: 杂志文章,meta分析

    doi:10.1007/s12072-020-10021-5

    authors: Yang Y,Huang A,Zhao Y

    更新日期:2020-03-01 00:00:00

  • New drugs for NAFLD: lessons from basic models to the clinic.

    abstract::The term nonalcoholic fatty liver disease (NAFLD) comprises a spectrum of increasingly harmful conditions ranging from nonalcoholic fatty liver (NAFL) to nonalcoholic steatohepatitis (NASH) to liver fibrosis and end-stage cirrhosis. NAFLD is the currently most common form of chronic liver disease in both adults and ch...

    journal_title:Hepatology international

    pub_type: 杂志文章,评审

    doi:10.1007/s12072-019-10001-4

    authors: Reimer KC,Wree A,Roderburg C,Tacke F

    更新日期:2020-01-01 00:00:00

  • Dynamic changes of T cell receptor repertoires in patients with hepatitis B virus-related acute-on-chronic liver failure.

    abstract:BACKGROUND AND AIMS:T cell-mediated immune injury plays a critical role in the pathogenesis of hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF). Given the high short-term mortality and crucial role of T cells in the disease progression, it is necessary to investigate the dynamics of T cell clones dur...

    journal_title:Hepatology international

    pub_type: 杂志文章

    doi:10.1007/s12072-019-10008-x

    authors: Shen G,Sun S,Huang J,Deng H,Xu Y,Wang Z,Tang X,Gong X

    更新日期:2020-01-01 00:00:00

  • Tenofovir versus entecavir in lowering the risk of hepatocellular carcinoma development in patients with chronic hepatitis B: a critical systematic review and meta-analysis.

    abstract:BACKGROUND:Controversy exists on whether tenofovir disoproxil fumarate (TDF) is superior to entecavir (ETV) in lowering the risk of hepatocellular carcinoma (HCC) development. This meta-analysis was performed to clarify this issue with critical clinical and methodological considerations. METHODS:PubMed, EMBASE, and Co...

    journal_title:Hepatology international

    pub_type: 杂志文章,meta分析

    doi:10.1007/s12072-019-10005-0

    authors: Li M,Lv T,Wu S,Wei W,Wu X,Ou X,Ma H,Chow SC,Kong Y,You H,Jia J

    更新日期:2020-01-01 00:00:00

  • Significant decrease in Faecalibacterium among gut microbiota in nonalcoholic fatty liver disease: a large BMI- and sex-matched population study.

    abstract:BACKGROUND:Compositional changes of the gut microbiota are known to occur in patients with nonalcoholic fatty liver disease (NAFLD); however, the changes did not corroborate between the studies. We evaluated the gut microbiota between NAFLD and non-NAFLD participants, excluding the influence of obesity and sex in this ...

    journal_title:Hepatology international

    pub_type: 杂志文章

    doi:10.1007/s12072-019-09987-8

    authors: Iino C,Endo T,Mikami K,Hasegawa T,Kimura M,Sawada N,Nakaji S,Fukuda S

    更新日期:2019-11-01 00:00:00

  • Complications constitute a major risk factor for mortality in hepatitis B virus-related acute-on-chronic liver failure patients: a multi-national study from the Asia-Pacific region.

    abstract:BACKGROUND AND AIM:Cirrhosis is a controversial determinant of mortality in HBV-related acute-on-chronic liver failure (HBV-ACLF). The present study aimed to explore the effects of cirrhosis and the associated risk factors, especially its complications, on the outcome of HBV-ACLF. METHODS:A prospective-retrospective c...

    journal_title:Hepatology international

    pub_type: 杂志文章

    doi:10.1007/s12072-019-09992-x

    authors: Chen T,Yang Z,Choudhury AK,Al Mahtab M,Li J,Chen Y,Tan SS,Han T,Hu J,Hamid SS,Huei LG,Ghazinian H,Nan Y,Chawla YK,Yuen MF,Devarbhavi H,Shukla A,Abbas Z,Sahu M,Dokmeci AK,Lesmana LA,Lesmana CRA,Xin S,Duan Z,

    更新日期:2019-11-01 00:00:00

  • An imbalance between stellate cells and γδT cells contributes to hepatocellular carcinoma aggressiveness and recurrence.

    abstract:PURPOSE:The diagnostic potential of hepatic stellate cells (HSCs) and γδT cells for patients with hepatocellular carcinoma (HCC) and their synergistic contributions to the prognosis of these patients have not yet been investigated. The aim of this study was to elucidate the prognostic value of these cells in HCC. METH...

    journal_title:Hepatology international

    pub_type: 杂志文章

    doi:10.1007/s12072-019-09969-w

    authors: Zhou BY,Gong JH,Cai XY,Wang JX,Luo F,Jiang N,Gong JP,Du CY,Liao R

    更新日期:2019-09-01 00:00:00

  • Reversal of NASH fibrosis with pharmacotherapy.

    abstract::NAFLD is a spectrum of liver disease starting with fatty liver at one end of the spectrum and cirrhosis or liver cancer at the other end. Worldwide, NAFLD has become one of the most common liver diseases and it has also become one of the leading indications for liver transplantation. Our understanding of the NAFLD epi...

    journal_title:Hepatology international

    pub_type: 杂志文章,评审

    doi:10.1007/s12072-019-09970-3

    authors: Alukal JJ,Thuluvath PJ

    更新日期:2019-09-01 00:00:00

  • Asparaginase-induced hepatotoxicity: rapid development of cholestasis and hepatic steatosis.

    abstract:BACKGROUND:L-Asparaginase is a bacterial enzyme used in the treatment of acute lymphoblastic leukemia. In the ongoing U.S. Drug-Induced Liver Injury Network (DILIN) prospective study, standard and pegylated asparaginase were the most frequent cause of liver injury with jaundice among anti-cancer agents (8 of 40: 20%). ...

    journal_title:Hepatology international

    pub_type: 杂志文章

    doi:10.1007/s12072-019-09971-2

    authors: Kamal N,Koh C,Samala N,Fontana RJ,Stolz A,Durazo F,Hayashi PH,Phillips E,Wang T,Hoofnagle JH,Drug-Induced Liver Injury Network.

    更新日期:2019-09-01 00:00:00

  • Current status and perspectives for computer-aided ultrasonic diagnosis of liver lesions using deep learning technology.

    abstract::An ultrasound (US) examination is a common noninvasive technique widely applied for diagnosis of a variety of diseases. Based on the rapid development of US equipment, many US images have been accumulated and are now available and ready for the preparation of a database for the development of computer-aided US diagnos...

    journal_title:Hepatology international

    pub_type: 杂志文章,评审

    doi:10.1007/s12072-019-09937-4

    authors: Nishida N,Yamakawa M,Shiina T,Kudo M

    更新日期:2019-07-01 00:00:00

  • Bacteroides in colonic mucosa-associated microbiota affects the development of minimal hepatic encephalopathy in patients with cirrhosis.

    abstract:BACKGROUND/PURPOSE:Gut microbiota has been associated with liver cirrhosis and, possibly, hepatic encephalopathy. However, only a few studies have examined the link between mucosa-associated microbiota (MAM) and minimal hepatic encephalopathy (MHE). Our aim was to investigate this relationship. METHODS:Twenty-four pat...

    journal_title:Hepatology international

    pub_type: 杂志文章

    doi:10.1007/s12072-019-09963-2

    authors: Haraguchi M,Miuma S,Masumoto H,Ichikawa T,Kanda Y,Sasaki R,Fukushima M,Miyaaki H,Taura N,Nakao K

    更新日期:2019-07-01 00:00:00

  • C1QTNF1-AS1 regulates the occurrence and development of hepatocellular carcinoma by regulating miR-221-3p/SOCS3.

    abstract:BACKGROUND:The aim of our study was to explore how C1QTNF1-AS1 regulated miR-221-3p/SOCS3 axis in human hepatocellular carcinoma (HCC). METHODS:Differentially expressed lncRNAs and genes were examined via RNA-seq. GO analysis and KEGG pathway enrichment analysis were carried out based on the function of dys-regulated ...

    journal_title:Hepatology international

    pub_type: 杂志文章

    doi:10.1007/s12072-019-09944-5

    authors: Li H,Zhang B,Ding M,Lu S,Zhou H,Sun D,Wu G,Gan X

    更新日期:2019-05-01 00:00:00

  • Immunological cure of HBV infection.

    abstract::Chronic hepatitis B virus (HBV) infection is a major global health burden and cure is rarely achieved by current antiviral therapies. Therefore, there is an urgent need for new therapeutic options. Immune modulation with the goal to restore dysfunctional HBV-specific immunity is an interesting target for new therapeut...

    journal_title:Hepatology international

    pub_type: 杂志文章,评审

    doi:10.1007/s12072-018-9912-8

    authors: Lang J,Neumann-Haefelin C,Thimme R

    更新日期:2019-03-01 00:00:00

  • Chinese guidelines on the management of ascites and its related complications in cirrhosis.

    abstract::The Chinese Society of Hepatology developed the current guidelines for the Management of Ascites and Its Related Complications in Cirrhosis based on the published evidences and the panelists' consensus. The guidelines provided recommendations for the diagnosis and management of cirrhotic ascites emphasizing a step-wis...

    journal_title:Hepatology international

    pub_type: 社论,实务指引

    doi:10.1007/s12072-018-09923-2

    authors: Chinese Society of Hepatology, Chinese Medical Association.,Xu X,Duan Z,Ding H,Li W,Jia J,Wei L,Linghu E,Zhuang H

    更新日期:2019-01-01 00:00:00

  • A changing paradigm: management and treatment of the HCV/HIV-co-infected patient.

    abstract::Hepatitis C virus (HCV) treatment in HIV/HCV co-infected individuals has renewed relevance given the ongoing opioid crisis and rise of new HIV and HCV infections associated with injection drug use. Patients co-infected with HIV and HCV demonstrate increased rates of hepatic fibrosis, progression to liver failure, and ...

    journal_title:Hepatology international

    pub_type: 杂志文章,评审

    doi:10.1007/s12072-018-9896-4

    authors: Abutaleb A,Sherman KE

    更新日期:2018-11-01 00:00:00

  • Non-alcoholic hepatic steatosis attenuates hepatitis B virus replication in an HBV-immunocompetent mouse model.

    abstract:OBJECTIVE:The relationship between chronic hepatitis B virus (HBV) infection and fatty liver in patients remains unclear. Although high-fat diets-induced hepatic steatosis was proved to reduce HBV replication in transgenic mice, the interplay between HBV and fatty liver in immunocompetent mouse model is yet to be eluci...

    journal_title:Hepatology international

    pub_type: 杂志文章

    doi:10.1007/s12072-018-9877-7

    authors: Hu D,Wang H,Wang H,Wang Y,Wan X,Yan W,Luo X,Ning Q

    更新日期:2018-09-01 00:00:00

  • Sofosbuvir-velpatasvir plus ribavirin in Japanese patients with genotype 1 or 2 hepatitis C who failed direct-acting antivirals.

    abstract:BACKGROUND/PURPOSE:In Japan, there is a growing population of patients with chronic hepatitis C virus (HCV) infection who failed a direct-acting antiviral (DAA)-based regimen. In this Phase 3 study, we evaluated sofosbuvir-velpatasvir plus ribavirin in Japanese patients with genotype 1 or 2 HCV infection who previously...

    journal_title:Hepatology international

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1007/s12072-018-9878-6

    authors: Izumi N,Takehara T,Chayama K,Yatsuhashi H,Takaguchi K,Ide T,Kurosaki M,Ueno Y,Toyoda H,Kakizaki S,Tanaka Y,Kawakami Y,Enomoto H,Ikeda F,Jiang D,De-Oertel S,McNabb BL,Camus G,Stamm LM,Brainard DM,McHutchison JG,M

    更新日期:2018-07-01 00:00:00

  • Impact of viral hepatitis B status on outcomes of intrahepatic cholangiocarcinoma: a meta-analysis.

    abstract:BACKGROUND AND AIMS:To estimate the impact of viral hepatitis B status on outcomes of intrahepatic cholangiocarcinoma. METHODS:We searched Pubmed and Embase for original articles that evaluated the impact of hepatitis B virus infection on outcomes of intrahepatic cholangiocarcinoma. The present study was conducted to ...

    journal_title:Hepatology international

    pub_type: 杂志文章,meta分析,评审

    doi:10.1007/s12072-018-9881-y

    authors: Jeong S,Luo G,Wang ZH,Sha M,Chen L,Xia Q

    更新日期:2018-07-01 00:00:00

  • Depression, fatigue and neurocognitive deficits in chronic hepatitis C.

    abstract::Patients with chronic hepatitis C virus (HCV) infection experience a range of symptoms including depression, fatigue and neurocognitive deficits, impairing quality of life. Depression, in particular, may be reactive to increased psychosocial stress, and the physical symptoms of advanced HCV or associated comorbidities...

    journal_title:Hepatology international

    pub_type: 杂志文章,评审

    doi:10.1007/s12072-018-9879-5

    authors: Yeoh SW,Holmes ACN,Saling MM,Everall IP,Nicoll AJ

    更新日期:2018-07-01 00:00:00

  • Targeting incretin hormones and the ASK-1 pathway as therapeutic options in the treatment of non-alcoholic steatohepatitis.

    abstract::Non-alcoholic fatty liver disease (NAFLD) is currently one of the leading forms of chronic liver disease, and its rising frequency worldwide has reached epidemic proportions. NAFLD, particularly its progressive variant NASH (non-alcoholic steatohepatitis), can lead to advanced fibrosis, cirrhosis, and HCC. The pathoph...

    journal_title:Hepatology international

    pub_type: 杂志文章,评审

    doi:10.1007/s12072-018-9854-1

    authors: Kovalic AJ,Satapathy SK,Chalasani N

    更新日期:2018-03-01 00:00:00

  • Balloon-occluded retrograde transvenous obliteration of varices: focusing on the portal hemodynamics and the recent techniques.

    abstract:PURPOSE:To evaluate the recent topics of Ballloon-occluded retrograde trasnvenous obliteration(B-RTO). METHOD:We overviewed the recent scientific papers regarding B-RTO. RESULT:B-RTO is a treatment method for occluding varices retrogradely using a sclerosing agent under balloon occlusion of a major draining vein. It ...

    journal_title:Hepatology international

    pub_type: 杂志文章,评审

    doi:10.1007/s12072-017-9813-2

    authors: Hirota S,Kobayashi K,Kako Y,Takaki H,Yamakado K

    更新日期:2018-02-01 00:00:00

  • Pharmacologic prevention of variceal bleeding and rebleeding.

    abstract:BACKGROUND:Variceal bleeding is a major complication of portal hypertension, which is associated with significant mortality. Moreover, patients surviving a variceal bleeding episode have very high risk of rebleeding, which is associated with mortality as high as that of the first bleed. Because of this, prevention of b...

    journal_title:Hepatology international

    pub_type: 杂志文章,评审

    doi:10.1007/s12072-017-9833-y

    authors: Baiges A,Hernández-Gea V,Bosch J

    更新日期:2018-02-01 00:00:00

  • Biology of portal hypertension.

    abstract::Portal hypertension develops as a result of increased intrahepatic vascular resistance often caused by chronic liver disease that leads to structural distortion by fibrosis, microvascular thrombosis, dysfunction of liver sinusoidal endothelial cells (LSECs), and hepatic stellate cell (HSC) activation. While the basic ...

    journal_title:Hepatology international

    pub_type: 杂志文章,评审

    doi:10.1007/s12072-017-9826-x

    authors: McConnell M,Iwakiri Y

    更新日期:2018-02-01 00:00:00

  • The utility of noninvasive scores in assessing the prevalence of nonalcoholic fatty liver disease and advanced fibrosis in type 1 diabetic patients.

    abstract:GOALS:The aim of our study is to assess the prevalence of nonalcoholic fatty liver disease (NAFLD) and advanced hepatic fibrosis in patients with type 1 diabetes (T1D) using simple noninvasive scores. BACKGROUND:There is paucity of data on the prevalence of NAFLD in T1D. Moreover, T1D could be a risk factor for advanc...

    journal_title:Hepatology international

    pub_type: 杂志文章

    doi:10.1007/s12072-017-9840-z

    authors: Singh A,Le P,Lopez R,Alkhouri N

    更新日期:2018-01-01 00:00:00

  • Liver failure determines the outcome in patients of acute-on-chronic liver failure (ACLF): comparison of APASL ACLF research consortium (AARC) and CLIF-SOFA models.

    abstract:BACKGROUND AND AIMS:Acute-on-chronic liver failure (ACLF) is a progressive disease associated with rapid clinical worsening and high mortality. Early prediction of mortality and intervention can improve patient outcomes. We aimed to develop a dynamic prognostic model and compare it with the existing models. METHODS:A ...

    journal_title:Hepatology international

    pub_type: 杂志文章

    doi:10.1007/s12072-017-9816-z

    authors: Choudhury A,Jindal A,Maiwall R,Sharma MK,Sharma BC,Pamecha V,Mahtab M,Rahman S,Chawla YK,Taneja S,Tan SS,Devarbhavi H,Duan Z,Yu C,Ning Q,Jia JD,Amarapurkar D,Eapen CE,Goel A,Hamid SS,Butt AS,Jafri W,Kim DJ,G

    更新日期:2017-09-01 00:00:00

  • A brief review on prognostic models of primary biliary cholangitis.

    abstract::Primary biliary cholangitis (PBC), previously known as primary biliary cirrhosis, is an autoimmune liver disease characterized by progressive destruction of small intrahepatic bile ducts. If left untreated, PBC may eventually result in end-stage liver disease. For better management of PBC and optimal allocation of med...

    journal_title:Hepatology international

    pub_type: 杂志文章,评审

    doi:10.1007/s12072-017-9819-9

    authors: Chen S,Duan W,You H,Jia J

    更新日期:2017-09-01 00:00:00

  • Treatment of chronic hepatitis C genotype 3 with Sofosbuvir-based therpy: a real-life study.

    abstract:BACKGROUND AND AIMS:Recently, Sofosbuvir was launched in India at affordable cost. We conducted a real-life study to determine the efficacy and safety of Sofosbuvir plus Ribavirin, with and without peginterferon-alfa 2a, in patients with chronic hepatitis C (CHC) genotype 3, the commonest genotype in South Asia. METHO...

    journal_title:Hepatology international

    pub_type: 杂志文章

    doi:10.1007/s12072-017-9794-1

    authors: Sidhu SS,Malhi NS,Goyal O,Singh R,Dutta U,Grover R,Sidhu JS,Nanda V,Saluja H,Bansal A,Singh G,Sehgal A,Kishore H,Sidhu S

    更新日期:2017-05-01 00:00:00

  • CSH guidelines for the diagnosis and treatment of drug-induced liver injury.

    abstract::Drug-induced liver injury (DILI) is an important clinical problem, which has received more attention in recent decades. It can be induced by small chemical molecules, biological agents, traditional Chinese medicines (TCM), natural medicines (NM), health products (HP), and dietary supplements (DS). Idiosyncratic DILI i...

    journal_title:Hepatology international

    pub_type: 社论

    doi:10.1007/s12072-017-9793-2

    authors: Yu YC,Mao YM,Chen CW,Chen JJ,Chen J,Cong WM,Ding Y,Duan ZP,Fu QC,Guo XY,Hu P,Hu XQ,Jia JD,Lai RT,Li DL,Liu YX,Lu LG,Ma SW,Ma X,Nan YM,Ren H,Shen T,Wang H,Wang JY,Wang TL,Wang XJ,Wei L,Xie Q,Xie W,

    更新日期:2017-05-01 00:00:00

  • Virus-induced hepatocellular carcinoma with special emphasis on HBV.

    abstract::Hepatocellular carcinoma (HCC) is a common malignant tumor with high lethality, and the hepatitis B virus (HBV) is a chief cause. HBV can accelerate HCC via multiple mechanisms. First, HBV induces immune reactions that lead to repeated hepatic inflammation, fibrosis and a deficient immune microenvironment. Subsequentl...

    journal_title:Hepatology international

    pub_type: 杂志文章,评审

    doi:10.1007/s12072-016-9779-5

    authors: Wang M,Xi D,Ning Q

    更新日期:2017-03-01 00:00:00

  • Existence of cancer stem cells in hepatocellular carcinoma: myth or reality?

    abstract::The cancer stem cell (CSC) hypothesis has been disproved in many cancers. CSCs may exist in blood cancer, while many epithelial cancers may not have CSCs but tumor-initiating cells (TICs). Several independent studies have provided strong evidence for existence of CSCs in brain, skin, and colon cancers (Mani et al. in ...

    journal_title:Hepatology international

    pub_type: 杂志文章

    doi:10.1007/s12072-016-9777-7

    authors: Machida K

    更新日期:2017-03-01 00:00:00

  • HATT: a phase IV, single-arm, open-label study of sorafenib in Taiwanese patients with advanced hepatocellular carcinoma.

    abstract:BACKGROUND:Sorafenib significantly improves survival in patients with advanced hepatocellular carcinoma (HCC). This phase IV study assessed sorafenib efficacy/safety in Taiwanese patients with advanced HCC and Child-Pugh A status. METHODS:All patients received 400 mg sorafenib BID. Safety, efficacy, sorafenib pharmaco...

    journal_title:Hepatology international

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1007/s12072-016-9774-x

    authors: Lin SM,Lu SN,Chen PT,Jeng LB,Chen SC,Hu CT,Yang SS,Le Berre MA,Liu X,Mitchell DY,Prins K,Grevel J,Peña CA,Meinhardt G

    更新日期:2017-03-01 00:00:00

  • Live donor liver transplantation for alcoholic hepatitis.

    abstract::Liver transplantation is a definitive therapy for patients with end-stage liver disease and cirrhosis, with improvement in survival and quality of life. Patients are carefully screened and selected for this modality of treatment to achieve maximum survival benefit. For example, a patient with hepatocellular carcinoma ...

    journal_title:Hepatology international

    pub_type: 杂志文章

    doi:10.1007/s12072-016-9770-1

    authors: Singal AK,Kamath PS

    更新日期:2017-01-01 00:00:00

  • Prednisolone plus S-adenosil-L-methionine in severe alcoholic hepatitis.

    abstract:PURPOSE/BACKGROUND:Severe alcoholic hepatitis (AH) is a life-threatening liver disease with a potential of 30-40 % mortality at 1 month. While steroids remain to be a first line therapy, they provide only about 50 % survival benefit. The aim of the study was to evaluate the efficacy of glucocorticoids plus S-adenosylme...

    journal_title:Hepatology international

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s12072-016-9751-4

    authors: Tkachenko P,Maevskaya M,Pavlov A,Komkova I,Pavlov C,Ivashkin V

    更新日期:2016-11-01 00:00:00

  • Hepatic stellate cells: fibrogenic, regenerative or both? Heterogeneity and context are key.

    abstract::Since their original identification, our understanding of the role of hepatic stellate cells in both health and disease continues to grow. Numerous studies have delineated the role of stellate cell activation in contributing to the pool of myofibroblasts responsible for liver fibrosis, and these have resulted in the d...

    journal_title:Hepatology international

    pub_type: 杂志文章,评审

    doi:10.1007/s12072-016-9758-x

    authors: Bansal MB

    更新日期:2016-11-01 00:00:00

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