abstract：BACKGROUND:Polyaminopropyl biguanide (INCI name) and polyhexamethylene biguanide (PHMB) are polymeric biguanides. PHMB is a broad-spectrum antimicrobial substance used as a preservative in many products. Due to our limited knowledge on PHMB contact allergy frequency and the fact that cases of allergic contact dermatiti...

journal_title：Contact dermatitis

authors： Sukakul T,Dahlin J,Pontén A,Antelmi A,Bruze M,Hamnerius N,Hauksson I,Isaksson M,Lejding T,Svedman C

更新日期：2020-10-24 00:00:00

abstract：BACKGROUND:Hyperkeratotic hand eczema (HHE) is a typical clinical hand eczema subtype with a largely unknown pathophysiology. OBJECTIVE:To investigate histopathology, expression of keratins (K), epidermal barrier proteins, and adhesion molecules in HHE. METHODS:Palmar skin biopsies (lesional and perilesional) were ob...

journal_title：Contact dermatitis

authors： Politiek K,Loman L,Pas HH,Diercks GFH,Lemmink HH,Jan SZ,van den Akker PC,Bolling MC,Schuttelaar MLA

更新日期：2020-09-01 00:00:00

abstract：:Toys are a reflection of the compounds used frequently in manufacturing. Allergic contact dermatitis to potties, metal toys, and children's jewelry is well known, however, there is a broad range of skin risks in toys. With the objective to identify and publicize the associated risk of contact dermatitis in children's ...

journal_title：Contact dermatitis

authors： Fenner J,Hadi A,Yeh L,Silverberg N

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Red tattoos are prone to allergic reactions. The identity of the allergen(s) is mostly unknown. OBJECTIVES:Chemical analysis of human skin biopsies from chronic allergic reactions in red tattoos to identify culprit pigment(s) and metals. MATERIAL AND METHODS:One hundred four dermatome biopsies were analyze...

journal_title：Contact dermatitis

authors： Serup J,Hutton Carlsen K,Dommershausen N,Sepehri M,Hesse B,Seim C,Luch A,Schreiver I

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Hand eczema is a disease with large variation in clinical presentation and severity. Scoring systems for quantitative severity assessment exist. However, they are observer-dependent. An objective quantitative tool for scoring of hand eczema would improve categorization of hand eczema. OBJECTIVE:To investiga...

journal_title：Contact dermatitis

authors： Hald M,Thyssen JP,Zachariae C,Røpke MA,Carstensen JM,Schultz N,Johansen JD

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Allergic contact dermatitis caused by leather is common, and several responsible allergens, such as tanning agents, glues, mercaptobenzothiazole derivatives, and dyes, but also antimicrobials and antifungals, are involved. MATERIAL AND METHODS:Three female patients were referred to the Departments of Dermat...

journal_title：Contact dermatitis

authors： Herman A,Goossens A,Tennstedt D,Bergendorff O,Isaksson M,Mowitz M,Baeck M

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Several studies have assessed the effect of patient education regarding hand eczema (HE) severity and quality of life. Few studies, however, have evaluated patients' knowledge. OBJECTIVES:To examine knowledge of skin protection in HE patients following a guided talk, and to identify variables associated wit...

journal_title：Contact dermatitis

authors： Topal Y,Agner T,van der Heiden J,Ebbehøj NE,Clemmensen KKB

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Positive patch test reactions to mixtures of oxidized terpenes containing allergenic hydroperoxides are frequently reported. However, human sensitization data for these hydroperoxides are not available. OBJECTIVES:To analyse and evaluate the human sensitization potential and potency of hydroperoxides in vit...

journal_title：Contact dermatitis

authors： Hennen J,Silva E Sousa M,Sahli F,Lichter J,Lepoittevin JP,Giménez-Arnau E,Blömeke B

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Lavender is commonly used in aromatherapy and in a broad range of personal and household products. It has been identified as a contact sensitizer, and has been reported to cause allergic contact dermatitis (ACD). OBJECTIVES:To report our experience with contact allergy and ACD caused by lavender, and to rai...

journal_title：Contact dermatitis

authors： Bingham LJ,Tam MM,Palmer AM,Cahill JL,Nixon RL

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:There are no Indian studies on the association between filaggrin gene (FLG) mutations and any dermatosis, including hand eczema. OBJECTIVES:To determine the prevalence of FLG mutations in Indian hand eczema patients, and examine associations between such mutations and any aetiological type of hand eczema. ...

journal_title：Contact dermatitis

authors： Handa S,Khullar G,Pal A,Kamboj P,De D

更新日期：2019-06-01 00:00:00

abstract：:In the first conundrum, permanent hair dyeing involves the use of aromatic amines such as p-phenylenediamine (PPD), whose oxidation is pivotal to the dyeing process, but also generates potent allergens. Despite prolonged efforts by industry to search for safer alternatives, hair dyeing is still reliant on this type of...

journal_title：Contact dermatitis

authors： Ferguson FJ,Pongpairoj K,Basketter DA,White IR,McFadden JP

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Colophonium is a common contact allergen that is present not only in household products but also in occupational settings. OBJECTIVES:To describe the sources of occupational exposure to colophonium and the occupations at risk of colophonium allergy. METHODS:We reviewed patch test files from the years 2002 ...

journal_title：Contact dermatitis

authors： Pesonen M,Suuronen K,Suomela S,Aalto-Korte K

更新日期：2019-01-01 00:00:00

abstract：:Allergic contact dermatitis caused by medical devices for diabetes patients has been increasingly described in the literature in the last few years. This article reviews the cases of allergic contact dermatitis caused by insulin pumps and glucose sensors reported since the 1970s, the culprit allergen(s), the results o...

journal_title：Contact dermatitis

authors： Herman A,de Montjoye L,Tromme I,Goossens A,Baeck M

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Panthenol (synonym: dexpanthenol), the alcohol analogue of panthothenic acid, is frequently included in moisturizers, wound-healing agents, and other cosmetics, and has been shown to be responsible for allergic contact dermatitis (ACD). OBJECTIVES:To evaluate the frequency of ACD caused by dexpanthenol, and...

journal_title：Contact dermatitis

authors： Fernandes RA,Santiago L,Gouveia M,Gonçalo M

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Preservatives such as formaldehyde and formaldehyde-releasers are common causes of contact allergy. OBJECTIVES:To examine trends in contact allergy to formaldehyde and formaldehyde-releasers in patch tested patients in Denmark over a 10-year period (2007-2016), and to investigate relevant sources of formald...

journal_title：Contact dermatitis

authors： Fasth IM,Ulrich NH,Johansen JD

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Common pesticides used in the region by agricultural workers may cause contact allergy. METHODS:Thirty agricultural workers with a history of pesticide exposure and dermatitis involving the face, neck, trunk or extremities, and 20 controls comprising 2 groups of 10 subjects each, group 1 with dermatitis and...

journal_title：Contact dermatitis

authors： Sharma A,Mahajan VK,Mehta KS,Chauhan PS,Sharma V,Sharma A,Wadhwa D,Chauhan S

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:The presence of hexavalent chromium (Cr[VI]), which is carcinogenic to humans and a dermal sensitizer, in tattoo inks may represent a serious health concern. The level of this impurity is limited to 0.2 mg/kg in tattoo inks by the European Resolution ResAP(2008)1. OBJECTIVES:To analyse 29 tattoo inks, produ...

journal_title：Contact dermatitis

authors： Bocca B,Senofonte O,Petrucci F

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Chromium (Cr) is a common skin sensitizer. The use of Cr(VI) in leather is restricted in the EU, but that of Cr(III) is not. OBJECTIVES:To assess whether prolonged exposure to Cr-tanned leather with mainly Cr(III) release may elicit allergic contact dermatitis in Cr-allergic individuals. METHOD:Ten Cr-alle...

journal_title：Contact dermatitis

authors： Hedberg YS,Erfani B,Matura M,Lidén C

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:An inverse relationship between disease severity and health-related quality of life (HR-QoL) in patients with hand eczema is well established, but modifying effects of demographic variables have been less well studied. OBJECTIVE:To identify the influence of metropolitan versus non-metropolitan residence on ...

journal_title：Contact dermatitis

authors： Nørreslet LB,Agner T,Sørensen JA,Ebbehøj NE,Bonde JP,Fisker MH

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:The diagnostic approach to drug hypersensitivity includes a detailed medical history, clinical examination, and skin testing and/or oral challenge with a culprit or alternative drug, depending on the type of reaction and the suspected drugs. Although skin testing is considered to be rather safe, cutaneous an...

journal_title：Contact dermatitis

authors： Papakonstantinou E,Müller S,Röhrbein JH,Wieczorek D,Kapp A,Jakob T,Wedi B

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:In 2011, a multicentre study was conducted in order to determine how hair dye manufacturers instructed consumers to perform a self-test prior to dyeing their hair, in order to identify individuals who are likely to react upon subsequent hair dyeing. A number of concerns were raised concerning the variability...

journal_title：Contact dermatitis

authors： Friis UF,Goosens A,Giménez-Arnau AM,Lidén C,Giménez-Arnau E,White IR,Alfonso JH,Uter W,Johansen JD

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Lanolin has been tested as lanolin alcohols (30% pet.) in baseline patch test series since 1969, and this has shown clinically relevant allergic contact dermatitis cases. OBJECTIVES:To investigate the temporal development of lanolin allergy (i.e. positive reaction to lanolin alcohols and/or Amerchol™ L-101)...

journal_title：Contact dermatitis

authors： Fransen M,Overgaard LEK,Johansen JD,Thyssen JP

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Contact urticaria (CU) and protein contact dermatitis (PCD) are mainly induced by an immediate, IgE-mediated immunological mechanism. Immediate sensitization is also linked to asthma and/or allergic rhinitis. OBJECTIVES:To report causes of work-induced CU and PCD, and to evaluate the occurrence of concomita...

journal_title：Contact dermatitis

authors： Helaskoski E,Suojalehto H,Kuuliala O,Aalto-Korte K

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:In 2016, dermatologists in Finland suspected contact allergy in several patients using moisturizers under the trade name Apobase®. Following a formulation change, Phenostat™, which is a mixture of phenoxyethanol, caprylhydroxamic acid, and methylpropanediol, was used as a preservative in Apobase® moisturizer...

journal_title：Contact dermatitis

authors： Ackermann L,Virtanen H,Korhonen L,Laukkanen A,Huilaja L,Riekki R,Hasan T

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:The patch test is considered to be the gold standard for diagnosing nickel (Ni) allergy. The lymphocyte transformation test (LTT) can also be used to detect Ni sensitization. However, little is known about the correlation between patch test and LTT reactions to Ni. OBJECTIVE:To establish and validate an LTT...

journal_title：Contact dermatitis

authors： Ständer S,Oppel E,Thomas P,Summer B

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Allergic contact dermatitis is known to occur in children with and without atopic dermatitis, but more data are needed on contact sensitization profiles in these two groups. OBJECTIVES:To identify frequent allergens in children with and without atopic dermatitis suspected of having allergic contact dermatit...

journal_title：Contact dermatitis

authors： Lubbes S,Rustemeyer T,Sillevis Smitt JH,Schuttelaar ML,Middelkamp-Hup MA

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Cobalt release from dental prostheses has been shown to elicit allergic reactions in cobalt-allergic patients. It is therefore important to investigate whether these prostheses are possible sources of sensitization. OBJECTIVES:To assess (i) cobalt release from dental prostheses and (ii) allergic reactions t...

journal_title：Contact dermatitis

authors： Al-Imam H,Benetti AR,Özhayat EB,Pedersen AM,Johansen JD,Thyssen JP,Jellesen MS,Gotfredsen K

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Contact allergy to rubber additives is common, particularly in patients with occupational dermatitis. OBJECTIVES:To descriptively analyse and compare patch test reactions in patients patch tested both with the baseline series and with an additional 'rubber series' as used in the department. METHODS:Patch t...

journal_title：Contact dermatitis

authors： Uter W,Warburton K,Weisshaar E,Simon D,Ballmer-Weber B,Mahler V,Fuchs T,Geier J,Wilkinson M

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Amines in epoxy hardeners are significant causes of occupational allergic contact dermatitis among workers who use epoxy resin systems. OBJECTIVES:To describe a novel group of contact allergens: N-(2-phenylethyl) derivatives of the reactive amine 1,3-benzenedimethanamine (1,3-BDMA). METHODS:We describe the...

journal_title：Contact dermatitis

authors： Pesonen M,Kuuliala O,Suomela S,Aalto-Korte K

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Thiurams and dithiocarbamates are structurally related sensitizing rubber accelerators. OBJECTIVES:To study patterns of simultaneous patch test reactions to thiurams and dithiocarbamates at the Finnish Institute of Occupational Health in 1991-2015. METHODS:We searched the patch test files for patients with...

journal_title：Contact dermatitis

authors： Aalto-Korte K,Pesonen M

更新日期：2016-12-01 00:00:00

abstract：:The local lymph node assay (LLNA) is used for assessing sensitizing potential in hazard identification and risk assessment for regulatory purposes. Sensitizing potency on the basis of the LLNA is categorized into extreme (EC3 value of ≤0.2%), strong (>0.2% to ≤2%), and moderate (>2%). To compare the sensitizing potenc...

journal_title：Contact dermatitis

authors： Lidén C,Yazar K,Johansen JD,Karlberg AT,Uter W,White IR

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Chromium is an important skin sensitizer. Exposure to it has been regulated in cement, and recently in leather. Studies on the deposition of chromium ions on the skin as a result of handling different chromium-containing materials are sparse, but could improve the risk assessment of contact sensitization and...

journal_title：Contact dermatitis

authors： Bregnbak D,Thyssen JP,Jellesen MS,Zachariae C,Johansen JD

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Workers exposed to epoxy products are at risk of developing allergic contact dermatitis. OBJECTIVES:To compare workers throughout the German construction industry with and without skin allergy to epoxy resins, hardeners, and/or reactive diluents, and to investigate which determinants are related to the deve...

journal_title：Contact dermatitis

authors： Spee T,Timmerman JG,Rühl R,Kersting K,Heederik DJ,Smit LA

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:The former 'EU Nickel Directive' and, since 2009, the REACH Regulation (item 27 of Annex XVII) do not include all metallic objects. The nickel content of tools is not regulated by the REACH Regulation, even if they may come into in prolonged contact with the skin. Tools might be possible sources of nickel an...

journal_title：Contact dermatitis

authors： Kickinger-Lörsch A,Bruckner T,Mahler V

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Foot eczema often occurs in combination with hand eczema. However, in contrast to the situation with hand eczema, knowledge about foot eczema is scarce, especially in occupational settings. OBJECTIVE:To evaluate the prevalence of foot eczema and associated factors in patients with hand eczema taking part in...

journal_title：Contact dermatitis

authors： Brans R,Hübner A,Gediga G,John SM

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Primin is the main contact allergen found in the ornamental plant Primula obconica Hance. OBJECTIVE:To analyse the temporal trend of sensitivity to primin in north-eastern Italy and to evaluate the associations with occupations in our geographical area. METHODOLOGY:From 1996 to 2012, 24 052 consecutive pat...

journal_title：Contact dermatitis

authors： Bongiorni L,Prodi A,Rui F,Belloni Fortina A,Corradin MT,Larese Filon F

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Allergic contact dermatitis caused by (meth)acrylates is well known, both in occupational and in non-occupational settings. Contact hypersensitivity to electrocardiogram (ECG) electrodes containing (meth)acrylates is rarely reported. OBJECTIVE:To report the first case of contact dermatitis caused by acrylic...

journal_title：Contact dermatitis

authors： Stingeni L,Cerulli E,Spalletti A,Mazzoli A,Rigano L,Bianchi L,Hansel K

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:The prevalence of p-phenylenediamine (PPD) sensitization is 4% in the patch tested population and varies between zero and 1.5% in the general population. Hair dye is a recognised sensitization source. OBJECTIVES:To define the prevalence rates of PPD sensitization in the general and patch tested populations ...

journal_title：Contact dermatitis

authors： Vogel TA,Coenraads PJ,Bijkersma LM,Vermeulen KM,Schuttelaar ML,EDEN Fragrance Study Group.

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Contact allergy prevalence rates change over time as a result of variations in allergen exposure. Data from patch test clinics are often used as markers for allergy trends. OBJECTIVES:The aim of the present retrospective study was to describe trends in rates of sensitization to allergens in the Swedish base...

journal_title：Contact dermatitis

authors： Fall S,Bruze M,Isaksson M,Lidén C,Matura M,Stenberg B,Lindberg M

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Natural and synthetic rubbers containing rubber accelerators are well-known causes of allergic contact dermatitis (ACD). Latex contact urticaria (CU) has been widely reported, especially when powdered latex glove use was commonplace. Consequently, interventions to reduce latex exposure by altering glove manu...

journal_title：Contact dermatitis

authors： Warburton KL,Urwin R,Carder M,Turner S,Agius R,Wilkinson SM

更新日期：2015-05-01 00:00:00