Determinants of epoxy allergy in the construction industry: a case-control study.

Abstract:

BACKGROUND:Workers exposed to epoxy products are at risk of developing allergic contact dermatitis. OBJECTIVES:To compare workers throughout the German construction industry with and without skin allergy to epoxy resins, hardeners, and/or reactive diluents, and to investigate which determinants are related to the development of epoxy allergy. METHODS:A questionnaire was completed by 179 epoxy allergy cases, and 151 epoxy workers as controls. Crude and adjusted odds ratios (ORs) and 95% confidence intervals (CIs) were estimated by the use of backwards stepwise logistic regression analysis. A multiple imputation approach was used to deal with missing data. RESULTS:Epoxy allergy was associated with an unusually high level of exposure to epoxy products [OR 2.13 (95%CI: 1.01-4.51)], wearing short sleeves or short trousers [OR 2.38 (95%CI: 1.03-5.52)], and not always using the correct type of gloves [OR 2.12 (95%CI: 1.12-4.01)]. A monotonic increasing risk was found with increasing exposure hours per week [OR 1.72 (95%CI: 1.39-2.14)]. Not using skin cream was inversely associated with epoxy allergy [OR 0.22 (95%CI: 0.08-0.59)]. Years working with epoxy products were inversely associated with epoxy allergy [OR 0.41 (95%CI: 0.27-0.61) per 10-year increase], suggesting a healthy worker survivor effect. CONCLUSIONS:Occupational epoxy allergy may be prevented by improving occupational hygiene behaviour and personal protection.

journal_name

Contact Dermatitis

journal_title

Contact dermatitis

authors

Spee T,Timmerman JG,Rühl R,Kersting K,Heederik DJ,Smit LA

doi

10.1111/cod.12529

subject

Has Abstract

pub_date

2016-05-01 00:00:00

pages

259-66

issue

5

eissn

0105-1873

issn

1600-0536

journal_volume

74

pub_type

杂志文章
  • How irritant is water? An overview.

    abstract::Water is a skin irritant which deserves attention because of its ubiquity. During the Vietnam war, soldiers suffered from painful swollen feet, so-called tropical immersion foot. In occupational dermatology, the importance of water as a skin irritant is especially appreciated. The irritancy of water has been demonstra...

    journal_title:Contact dermatitis

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-0536.1999.tb06990.x

    authors: Tsai TF,Maibach HI

    更新日期:1999-12-01 00:00:00

  • Ascertainment of hand dermatitis using a symptom-based questionnaire; applicability in an industrial population.

    abstract::In this study, the applicability of a symptom-based questionnaire on hand dermatitis was assessed in a population of rubber workers. The questionnaire was previously validated in a study among nurses. 224 subjects employed in 9 different companies completed a questionnaire on skin complaints. Subsequently, 202 workers...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1034/j.1600-0536.2000.042004202.x

    authors: Vermeulen R,Kromhout H,Bruynzeel DP,de Boer EM

    更新日期:2000-04-01 00:00:00

  • Cinnamic aldehyde in toothpaste. 1. Clinical aspects and patch tests.

    abstract::Although cinnamon is known to cause dermatitis in bakers and confectioners, it has only rarely been reported as causing trouble in food or cosmetics. A newly-formulated 'spicy' toothpaste containing cinnamon as a flavouring agent was the cause of oral symptoms in eight patients referred to clinics in Buckinghamshire a...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1975.tb05330.x

    authors: Magnusson B,Wilkinson DS

    更新日期:1975-01-01 00:00:00

  • Cross-reaction patterns in patients with contact allergy to simple methylol phenols.

    abstract::The low-molecular-weight phenols 2-methylol phenol (2-MP), 4-methylol phenol (4-MP), 2,4,6-trimethylol phenol (2,4,6-MP), 3-methylol phenol (3-MP), 2,4-dimethylol phenol (2,4-MP), and 2,6-dimethylol phenol (2,6-MP) are contact sensitizers in resins based on phenol and formaldehyde (P-F-R). Other chemically related low...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1997.tb00044.x

    authors: Bruze M,Zimerson E

    更新日期:1997-08-01 00:00:00

  • Occupational allergic contact dermatitis from cinnamon including one case from airborne exposure.

    abstract:BACKGROUND:The bark of the cinnamon tree is used as a spice; its flavour is from an essential oil containing mainly cinnamal. OBJECTIVE:To report new cases of occupational allergic contact dermatitis (ACD) from cinnamon and a novel case of airborne cinnamon contact allergy. METHODS:We examined the patient material of...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2008.01486.x

    authors: Ackermann L,Aalto-Korte K,Jolanki R,Alanko K

    更新日期:2009-02-01 00:00:00

  • Clinical morphology of sodium lauryl sulfate (SLS) and nonanoic acid (NAA) irritant patch test reactions at 48 h and 96 h in 152 subjects.

    abstract::In this study of 152 women, comparison of patch test responses between 2 irritants over 96 h at 2 symmetrical anatomical sites is studied. 2 irritants, each at 4 different concentrations (nonanoic acid (NAA) 80%, 40%, 20%, 10%; sodium lauryl sulfate (SLS) 3%, 2%, 1% and 0.5%) and using propan-1ol and 'water for inject...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1998.tb05916.x

    authors: Reiche L,Willis C,Wilkinson J,Shaw S,de Lacharrière O

    更新日期:1998-11-01 00:00:00

  • Topical botanically derived products: use, skin reactions, and usefulness of patch tests. A multicentre Italian study.

    abstract:BACKGROUND:The evidence on the safety of topical preparations containing botanical extracts is limited. OBJECTIVES:To assess (i) the use of botanically derived compounds in a large population, (ii) the incidence of cutaneous side-effects, and (iii) the diagnostic usefulness of patch testing. METHODS:A questionnaire w...

    journal_title:Contact dermatitis

    pub_type: 杂志文章,多中心研究

    doi:10.1111/cod.12124

    authors: Corazza M,Borghi A,Gallo R,Schena D,Pigatto P,Lauriola MM,Guarneri F,Stingeni L,Vincenzi C,Foti C,Virgili A

    更新日期:2014-02-01 00:00:00

  • Nickel dermatitis from cheap earrings.

    abstract::In 1988, 64% of our patients patch test positive to at least 1 allergen of the ICDRG standard series were nickel sensitive. In 70% of 300 patients evaluated, dermatitis started on the earlobes and was related to the regular wearing of cheap earrings. At the same time, 62% of 735 young schoolgirls were found to have de...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1989.tb03203.x

    authors: Santucci B,Ferrari PV,Cristaudo A,Cannistraci C,Picardo M

    更新日期:1989-10-01 00:00:00

  • Occupational contact dermatitis from Cichorium (chicory, endive) and Lactuca (lettuce).

    abstract::In two cases, occupational contact dermatitis was found to be due to chicory (Cichorium) used as a salad plant. In one of the two cases, contact sensitivity to letuce (Lactuca) was also observed. The sesquiterpene lactones of the plant may be the allergens. ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1975.tb05444.x

    authors: Friis B,Hjorth N,Vail JT Jr,Mitchell JC

    更新日期:1975-10-01 00:00:00

  • Concurrent sensitization to metals and occupation.

    abstract:BACKGROUND:Cosensitization to nickel, cobalt and chromium occurs in the general population and in some occupational groups. OBJECTIVES:To estimate the isolated and concurrent occurrence of nickel, cobalt and chromium contact sensitization and their association with individual and occupational risk factors. PATIENTS/M...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2012.02100.x

    authors: Rui F,Bovenzi M,Prodi A,Fortina AB,Romano I,Corradin MT,Filon FL

    更新日期:2012-12-01 00:00:00

  • Hidden risks in toys: A systematic review of pediatric toy contact dermatitis.

    abstract::Toys are a reflection of the compounds used frequently in manufacturing. Allergic contact dermatitis to potties, metal toys, and children's jewelry is well known, however, there is a broad range of skin risks in toys. With the objective to identify and publicize the associated risk of contact dermatitis in children's ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.13500

    authors: Fenner J,Hadi A,Yeh L,Silverberg N

    更新日期:2020-05-01 00:00:00

  • Allergic contact dermatitis to pimecrolimus.

    abstract::Pimecrolimus suppresses the proinflammatory cytokine production of cutaneous T and mast cells (1). It is used to treat atopic dermatitis and is the active ingredient in the topical formulation pimecrolimus 1.0% cream (Elidel, Novartis Pharma AG, Basel, Switzerland). ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2007.00822.x

    authors: Saitta P,Brancaccio R

    更新日期:2007-01-01 00:00:00

  • Hand eczema patients' knowledge of skin protection following a guided talk-A retrospective study with a follow-up questionnaire.

    abstract:BACKGROUND:Several studies have assessed the effect of patient education regarding hand eczema (HE) severity and quality of life. Few studies, however, have evaluated patients' knowledge. OBJECTIVES:To examine knowledge of skin protection in HE patients following a guided talk, and to identify variables associated wit...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.13264

    authors: Topal Y,Agner T,van der Heiden J,Ebbehøj NE,Clemmensen KKB

    更新日期:2019-08-01 00:00:00

  • Patch testing of 490 patients in Hong Kong.

    abstract::Patch testing, using European standard allergens and suspected causative substances brought in by patients, was carried out in 490 patients with eczema in Hong Kong and 437 completed the test. Before patch testing, 244, 141 and 105 patients were diagnosed as having contact dermatitis, endogenous eczema and unclassifie...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1996.tb02261.x

    authors: Lee TY,Lam TH

    更新日期:1996-07-01 00:00:00

  • Skin protection in bakers' apprentices.

    abstract::Skin protection measures - barrier creams, protective gloves - and skin care are widely recommended for the prevention of occupational hand dermatitis (HD) in skin risk professions, but there is hardly anything known about uptake levels of the measures. The objective of this controlled intervention study was to quanti...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1034/j.1600-0536.2002.460204.x

    authors: Bauer A,Kelterer D,Bartsch R,Pearson J,Stadeler M,Kleesz P,Elsner P,Williams H

    更新日期:2002-02-01 00:00:00

  • Influence of area of application of allergen on sensitization in contact dermatitis.

    abstract::There are at least 2 quantitative variables when applying allergens to obtain sensitization: the absolute amount of allergen and the surface concentration. This review analyzes the limited studies on surface concentration and determines surface area threshold levels for the allergens documented in the literature. ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-0536.1992.tb03280.x

    authors: Upadhye MR,Maibach HI

    更新日期:1992-11-01 00:00:00

  • Value of patch tests in clindamycin-related drug eruptions.

    abstract:BACKGROUND:Patch tests help to confirm the aetiology of the cutaneous adverse drug reactions involving delayed hypersensitivity mechanisms, but the results vary with the pattern of skin reaction and the culprit drug. OBJECTIVES:To analyse the results of patch tests in patients with cutaneous adverse drug reactions imp...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2011.01942.x

    authors: Pereira N,Canelas MM,Santiago F,Brites MM,Gonçalo M

    更新日期:2011-10-01 00:00:00

  • Rejection of metal to metal prosthesis and skin sensitivity to cobalt.

    abstract::Metal to metal prostheses give satisfactory results in 90% of patients. About half of the failure rate may be due to allergic reaction to the metals involved, particularly cobalt. A total of 35 patients in this unsatisfactory group have been patch-tested; 16 were positive to metals, 13 to cobalt, 4 to nickel, and 2 to...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1976.tb02986.x

    authors: Munro-Ashman D,Miller AJ

    更新日期:1976-04-01 00:00:00

  • Do cool water or physiologic saline compresses enhance resolution of experimentally-induced irritant contact dermatitis?

    abstract::Acute irritant contact dermatitis (ICD) is frequently treated with cool water or saline compresses. While presumed effective, little quantitative evaluation documents the treatment's benefit. This study sought to determine the efficacy of both distilled water and physiologic saline compresses on experimentally-induced...

    journal_title:Contact dermatitis

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1034/j.1600-0536.2001.045003146.x

    authors: Levin CY,Maibach HI

    更新日期:2001-09-01 00:00:00

  • Penetration and haptenation of p-phenylenediamine.

    abstract::Although p-phenylenediamine (PPD) has been recognized as an extreme sensitizer for many years, the exact mechanism of sensitization has not been elucidated yet. Penetration and the ability to bind to proteins are the first two hurdles that an allergen has to overcome to be able to sensitize. This review is an overview...

    journal_title:Contact dermatitis

    pub_type: 杂志文章,评审

    doi:10.1111/cod.12032

    authors: Pot LM,Scheitza SM,Coenraads PJ,Blömeke B

    更新日期:2013-04-01 00:00:00

  • Contact dermatitis from the epoxy resins tetraglycidyl-4,4'-methylene dianiline and o-diglycidyl phthalate in composite material.

    abstract::An outbreak of dermatitis occurred in an aircraft factory using epoxy resin composite material. Of 25 operatives, 14 gave positive patch test reactions to the composite material and/or diglycidylether of bisphenol A (DGEBA), tetraglycidyl-4,4'-methylene dianiline (TGMDA), and o-diglycidyl phthalate. This report seems ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1984.tb00931.x

    authors: Burrows D,Fregert S,Campbell H,Trulsson L

    更新日期:1984-08-01 00:00:00

  • The major allergen of Dendropanax trifidus Makino.

    abstract::Dendropanax trifidus Makino (family Araliaceae, syn. Gilibertia trifida Makino) has been reported as causing allergic contact dermatitis in Japan. To identify the major allergen, fractionated extracts of fresh leaves of Dendropanax trifidus were patch tested on 2 patients with hypersensitivity to the plant. Cis-9,17-o...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1997.tb00212.x

    authors: Oka K,Saito F,Yasuhara T,Sugimoto A

    更新日期:1997-05-01 00:00:00

  • Sensitivity to some rubber additives.

    abstract::The frequency of positive patch tests to 13 rubber accelerators in Poland was recorded. Of particular interest was the relatively large group of patients positive to several, mostly chemically unrelated, accelerators. The mechanism of this multiple sensitivity is discussed. Positive tests to N-isopropyl-N-phenyl-p-phe...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1976.tb02974.x

    authors: Rudzki E,Ostaszewski K,Grzywa Z,Kozlowska A

    更新日期:1976-02-01 00:00:00

  • Cross-reactivity between sensitivity to thimerosal and photosensitivity to piroxicam in guinea pigs.

    abstract::Piroxicam (PXM) is a nonsteroidal anti-inflammatory drug which may induce a photosensitive eruption shortly after administration. We examined whether animals sensitized to thimerosal developed a photosensitivity to PXM. Male Hartley strain guinea pigs were sensitized to thimerosal, thiosalicylate and PXM separately. T...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1991.tb01769.x

    authors: Kitamura K,Osawa J,Ikezawa Z,Nakajima H

    更新日期:1991-07-01 00:00:00

  • Lymphomatoid contact dermatitis due to ethylenediamine dihydrochloride.

    abstract::A case of contact sensitivity to ethylenediamine dihydrochloride is reported. The clinical and histological features were in keeping with early mycosis fungoides. The eruption cleared with avoidance of the allergen. Continued contact with the allergen was traced to its retention in a trouser pocket lining. The term "l...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1982.tb04135.x

    authors: Wall LM

    更新日期:1982-01-01 00:00:00

  • Occupational contact urticaria caused by cyclic acid anhydrides.

    abstract:BACKGROUND:Cyclic acid anhydrides often cause allergic respiratory diseases, but contact urticaria because of these anhydrides has been considered rare. OBJECTIVE:We describe 21 patients diagnosed with occupational contact urticaria at the Finnish Institute of Occupational Health during the period 1990-2006. METHOD:P...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2009.01526.x

    authors: Helaskoski E,Kuuliala O,Aalto-Korte K

    更新日期:2009-04-01 00:00:00

  • Different pathways in irritant contact eczema? Early differences in the epidermal elemental content and expression of cytokines after application of 2 different irritants.

    abstract::The epidermal response to 2 different irritants, nonanoic acid (NAA) and sodium lauryl sulfate (SLS), was investigated with 2 different methods. NAA 80% and SLS 4% were applied under occlusion for up to 24 h. Elemental changes were determined in cryosections by x-ray microanalysis. Compared to unexposed skin a signifi...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1996.tb02416.x

    authors: Grängsjö A,Leijon-Kuligowski A,Törmä H,Roomans GM,Lindberg M

    更新日期:1996-12-01 00:00:00

  • Higher allergenicity of high molecular weight hydrolysed wheat protein in cosmetics for percutaneous sensitization.

    abstract:BACKGROUND:Wheat protein derivatives are used in a variety of products worldwide. Gluten is commercially used 'as is' or with modifications such as hydrolysis, which is carried out to overcome its insolubility. Several cases of contact urticaria following exposure to hydrolysed wheat protein (HWP) in cosmetics or of an...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2012.02168.x

    authors: Chinuki Y,Takahashi H,Dekio I,Kaneko S,Tokuda R,Nagao M,Fujisawa T,Morita E

    更新日期:2013-02-01 00:00:00

  • Triphenyl phosphate allergy from spectacle frames.

    abstract::A case of triphenyl phosphate allergy from spectacle frames is reported. Patch tests with analytical grade triphenyl phosphate, tri-m-cresyl phosphate, and tri-p-cresyl phosphate in the concentrations 5%, 0.5% and 0.05% pet. showed positive reactions to 0.05% triphenyl phosphate and 0.5% tri-m-cresyl phosphate, but no...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1986.tb01367.x

    authors: Carlsen L,Andersen KE,Egsgaard H

    更新日期:1986-11-01 00:00:00

  • Increase in contact allergy to fragrances: patch-test results 1989-1998.

    abstract::We report the results of patch tests with fragrance-mix as a part of the standard series carried out over the last 10 years (1989-1998) during routine testing of 6129 patients in our department. 5.9% of the total number of patients who were patch tested were positive to fragrance mix. The sex ratio was 2.3:1 with a fe...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1034/j.1600-0536.2000.043002107.x

    authors: Lunder T,Kansky A

    更新日期:2000-08-01 00:00:00