The preservative 2-(thiocyanomethylthio)benzothiazole: A potential allergen in leather products.

Abstract:

BACKGROUND:Allergic contact dermatitis caused by leather is common, and several responsible allergens, such as tanning agents, glues, mercaptobenzothiazole derivatives, and dyes, but also antimicrobials and antifungals, are involved. MATERIAL AND METHODS:Three female patients were referred to the Departments of Dermatology in a Belgian university hospital following skin reactions caused by leather products (shoes, belt, and car seats). They were patch tested with the European baseline series and samples of suspected leather products, and additionally with 2-(thiocyanomethylthio)benzothiazole (TCMTB), an antifungal agent previously reported to be a contact allergen in footwear. Chromatographic analyses of samples of all the leather materials tested were performed at the Department of Occupational and Environmental Dermatology in Malmö, Sweden. RESULTS:The patients reacting to the leather samples were shown to be sensitized to TCMTB, the presence of which could be confirmed by chemical analyses of samples obtained from the patients. CONCLUSION:Patch tests with TCMTB should be considered in patients with contact dermatitis caused by leather items.

journal_name

Contact Dermatitis

journal_title

Contact dermatitis

authors

Herman A,Goossens A,Tennstedt D,Bergendorff O,Isaksson M,Mowitz M,Baeck M

doi

10.1111/cod.13295

subject

Has Abstract

pub_date

2019-10-01 00:00:00

pages

262-265

issue

4

eissn

0105-1873

issn

1600-0536

journal_volume

81

pub_type

杂志文章
  • Sensitization capacity of ethylenediamine in the guinea pig and induction of unresponsiveness.

    abstract::The sensitization capacity of ethylenediamine was examined by the guinea pig maximization test and compared with dinitrochlorobenzene. Ethylenediamine was found to be a potent sensitizer. An attempt at oral induction of unresponsiveness (tolerance) was unsuccessful with ethylenediamine and DNCB and the same negative r...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1979.tb04881.x

    authors: Eriksen K

    更新日期:1979-09-01 00:00:00

  • Occupational dermatoses in a metalworking plant.

    abstract::In a plant producing advanced components for engines and drivelines we undertook a survey of occupational dermatoses, based on a questionnaire, clinical examination, and patch testing with a standard series and a series of samples from the working environment. The questionnaire was given to all 430 employees and it wa...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1034/j.1600-0536.2003.480205.x

    authors: Gruvberger B,Isaksson M,Frick M,Pontén A,Bruze M

    更新日期:2003-02-01 00:00:00

  • A clinical and patch test study of adult widespread eczema.

    abstract::The purpose of this study was to investigate the role of contact hypersensitivity (CHS) in adult widespread eczema (WE) and to analyse the aetiology of WE. 108 consecutive adult WE patients were patch tested. 352 patients with suspected localized allergic contact dermatitis (ACD) tested in the same period served as a ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1034/j.1600-0536.2002.470605.x

    authors: Li LF,Wang J

    更新日期:2002-12-01 00:00:00

  • Bacteria and soluble oil dermatitis.

    abstract::Simultaneous investigation of the bacterial flora of a soluble oil in use as a metalworking fluid and of the skin of machine operatives exposed to that soluble oil did not support the hypothesis that bacteria in soluble oil emulsions colonise the skin and either initiate or maintain the dermatitis associated with solu...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1980.tb03873.x

    authors: Rycroft RJ

    更新日期:1980-01-01 00:00:00

  • A comparison of three guinea-pig sensitization procedures for the detection of 19 reported human contact sensitizers.

    abstract::A maximization test (after Magnusson & Kligman 1970), a single injection adjuvant test (SIAT) and a modified Draize test procedure for assessing contact sensitization potential in guinea-pigs have been compared for their ability to detect 19 known human contact sensitizers. The results show that the modified Draize pr...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1981.tb04060.x

    authors: Goodwin BF,Crevel RW,Johnson AW

    更新日期:1981-09-01 00:00:00

  • Hand dermatoses and contact allergic reactions in construction workers exposed to epoxy resins.

    abstract::In 23/135 (18%) workers exposed to epoxy resins, a work-related dermatosis on the hands and/or forearms had been present during the past 3 years. In 9 persons, the occupational dermatosis was still present at the time of investigation. In all workers, patch tests were performed with epoxy resin, isophoronediamine, tri...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1984.tb00020.x

    authors: van Putten PB,Coenraads PJ,Nater JP

    更新日期:1984-03-01 00:00:00

  • Contact urticaria and asthma from denatonium benzoate (Bitrex).

    abstract::A 30-year-old male developed asthma and pruritus after using an insecticidal spray (Pyrex). The same symptoms appeared with an alcoholic skin disinfectant (M-sprit) and other spirituous preparations denaturated with denatonium benzoate (Bitrex). An open epicutaneous test (20 min) showed wheal and erythema to Pyrex, M-...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1980.tb05568.x

    authors: Björkner B

    更新日期:1980-12-01 00:00:00

  • Corticosteroid contact hypersensitivity: what vehicle and concentration?

    abstract::The correct concentration and vehicle for patch testing with corticosteroids is in many instances not known. The results of this study suggest that 1% in ethanol should be the initial choice, unless it can be shown that petrolatum as a vehicle is as sensitive (tixocortol pivalate and budesonide). We could find no evid...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1996.tb02212.x

    authors: Wilkinson SM,Beck MH

    更新日期:1996-05-01 00:00:00

  • Occupational airborne contact dermatitis caused by thyme dust.

    abstract::The aim of the study was to assess occupational hazards to the farmer's skin associated with processing thyme (Thymus vulgaris L.). 46 farmers were studied during the threshing of dried thyme. They were questioned about work-related skin problems and examined before and after work. In all persons, serum thyme-specific...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1034/j.1600-0536.2001.044004235.x

    authors: Spiewak R,Skorska C,Dutkiewicz J

    更新日期:2001-04-01 00:00:00

  • Prognosis and work absence due to occupational contact dermatitis.

    abstract::The consequences of a diagnosis of occupational contact dermatitis (OCD) were investigated using cases available from the voluntary surveillance scheme, EPIDERM. Cases of OCD reported from November 1994 to September 1995 were identified and sampled to give at least 100 cases of allergic, irritant and mixed OCD reporte...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1034/j.1600-0536.2002.460505.x

    authors: Adisesh A,Meyer JD,Cherry NM

    更新日期:2002-05-01 00:00:00

  • Coin exposure may cause allergic nickel dermatitis: a review.

    abstract::Nickel is used in coins because the metal has beneficial properties, including price, colour, weight, and corrosion resistance, and also because it is easy to stamp. It has often been claimed that the duration of skin contact with coins is too short to cause nickel release and dermatitis. However, it is well known by ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-0536.2012.02127.x

    authors: Thyssen JP,Gawkrodger DJ,White IR,Julander A,Menné T,Lidén C

    更新日期:2013-01-01 00:00:00

  • Evidence of increased skin irritation after wet work: impact of water exposure and occlusion.

    abstract:BACKGROUND:Exposure to humid environments/water and prolonged glove occlusion are both believed to cause irritant contact dermatitis. OBJECTIVES:To study the effects of different forms of wet work, especially the differences between water exposure and occlusion, by using an experimental model simulating occupational w...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2012.02063.x

    authors: Fartasch M,Taeger D,Broding HC,Schöneweis S,Gellert B,Pohrt U,Brüning T

    更新日期:2012-10-01 00:00:00

  • Prevalence of benzocaine and lidocaine patch test sensitivity in Denmark: temporal trends and relevance.

    abstract:UNLABELLED:BACKGROUND. Allergens included in the European baseline series should result in positive patch test reactions in at least 1% of a patch test population. Inclusion of local anaesthetics other than benzocaine in the baseline series has previously been debated. OBJECTIVES:To investigate temporal trends of benz...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2010.01858.x

    authors: Thyssen JP,Engkilde K,Menné T,Johansen JD

    更新日期:2011-08-01 00:00:00

  • Methacrylates in dental restorative materials.

    abstract::Commercial dental restorative materials were analysed in order to obtain information about the occurrence of sensitizing acrylates. Acetone-soluble methacrylates of 7 bonding materials, 8 composite resins and 2 glass ionomers were identified by gas chromatography with mass-selective detection and quantified by liquid ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.0105-1873.2004.00336.x

    authors: Henriks-Eckerman ML,Suuronen K,Jolanki R,Alanko K

    更新日期:2004-04-01 00:00:00

  • Chromium allergy: significance of both Cr(III) and Cr(VI).

    abstract::Most studies investigating chromium allergy have been performed with Cr(VI). However, real exposure to chromium from leather products includes both Cr(III) and Cr(VI). We have determined and compared the minimum elicitation threshold (MET) concentration for Cr(III) and Cr(VI) in Cr(VI)-sensitive patients. In addition,...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.0105-1873.2003.0230.x

    authors: Hansen MB,Johansen JD,Menné T

    更新日期:2003-10-01 00:00:00

  • Allergic contact dermatitis of the lip margins from para-tertiary-butylphenol in a lip liner.

    abstract::We describe the use of gas chromatography with mass spectrometry (GC-MS) in the investigation of a case of allergic contact dermatitis of the lip margins caused by a lip liner. Patch testing identified sensitization to para-tertiary-butylphenol-formaldehyde resin (PTBP-FR), a resin glue frequently used in leather work...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1993.tb03375.x

    authors: Angelini E,Marinaro C,Carrozzo AM,Bianchi L,Delogu A,Giannello G,Nini G

    更新日期:1993-03-01 00:00:00

  • Epidemiological, clinical and allergological observations on pompholyx.

    abstract::We have studied a group of 104 patients with pompholyx, to investigate the relationship between allergological factors and its etiopathogenesis. The following examinations were performed: blood sampling (routine tests and IgE levels), allergological tests (patch, prick, intradermal, and oral provovation tests with nic...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1992.tb00862.x

    authors: Lodi A,Betti R,Chiarelli G,Urbani CE,Crosti C

    更新日期:1992-01-01 00:00:00

  • Gold trichloride and gold sodium thiosulfate as markers of contact allergy to gold.

    abstract::The usefulness of a trivalent gold salt, gold trichloride (GTC), was evaluated as a marker of contact allergy to gold. Patients patch test-positive or patch test-negative to gold sodium thiosulfate (GSTS), 13 subjects of each, were patch tested with dilution series of GTC and equimolar concentrations of GSTS. In order...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.0105-1873.2005.00648.x

    authors: Möller H,Ahnlide I,Gruvberger B,Bruze M

    更新日期:2005-08-01 00:00:00

  • Cosmetics, the consumer, the factory worker and the occupational physician. Suggestions concerning ways to determine untoward dermatologic effects of cosmetics.

    abstract::Methods for investigating contact eczematous patients and for measuring the sensitizing potential of various substances are well known and in general, sufficiently effective. This is not true for irritant dermatitis, or for possible (skin) irritant substances; moreover, cosmetics commonly do not contain acutely harmfu...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1975.tb05305.x

    authors: Malten KE

    更新日期:1975-01-01 00:00:00

  • Guidelines for visualization of cutaneous blood flow by laser Doppler perfusion imaging. A report from the Standardization Group of the European Society of Contact Dermatitis based upon the HIRELADO European community project.

    abstract::This report reviews how to set up a laser Doppler perfusion imaging system intended for visualization of skin blood perfusion, capture images and evaluate the results obtained. A brief summary of related papers published in the literature within the areas of skin irritant and allergy patch testing, microdialysis and s...

    journal_title:Contact dermatitis

    pub_type: 指南,杂志文章,实务指引,评审

    doi:10.1034/j.1600-0536.2002.460301.x

    authors: Fullerton A,Stücker M,Wilhelm KP,Wårdell K,Anderson C,Fischer T,Nilsson GE,Serup J,European Society of Contact Dermatitis Standardization Group.

    更新日期:2002-03-01 00:00:00

  • Hidden risks in toys: A systematic review of pediatric toy contact dermatitis.

    abstract::Toys are a reflection of the compounds used frequently in manufacturing. Allergic contact dermatitis to potties, metal toys, and children's jewelry is well known, however, there is a broad range of skin risks in toys. With the objective to identify and publicize the associated risk of contact dermatitis in children's ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.13500

    authors: Fenner J,Hadi A,Yeh L,Silverberg N

    更新日期:2020-05-01 00:00:00

  • Contact sensitivity to flavourings and perfumes in atopic dermatitis.

    abstract::16 children with atopic dermatitis and 4 nonatopics were skin tested with flavourings and perfumes. Immediate reactions to balsam of Peru and fragrance-mix were found in 9 atopics, and none among nonatopics. An irritant is more probable than an immunologic mechanism. Allergen solutions should probably be assayed at a ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1992.tb05196.x

    authors: Abifadel R,Mortureux P,Perromat M,Ducombs G,Taieb A

    更新日期:1992-07-01 00:00:00

  • Allergic and irritant patch test reactions and atopic disease.

    abstract::This study presents a profile of patients with chronic recalcitrant eczematous disease referred by dermatologists for contact allergy evaluation. Allergic contact dermatitis (ACD) and irritant responses were carefully defined, as was the presence or absence of atopy obtained by history. Of 410 patients studied, 44% ha...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1996.tb02143.x

    authors: Klas PA,Corey G,Storrs FJ,Chan SC,Hanifin JM

    更新日期:1996-02-01 00:00:00

  • Age distribution of the incidence of contact sensitivity to standard allergens.

    abstract::The incidence of contact sensitivity to standard allergens present in the daily environment, such as chromium ion, cobalt, nickel and formaldehyde, is found to decrease in the fourth decade. It strongly suggests the presence of some immunoregulation in human beings, because sensitivity to these allergens should be equ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1979.tb04910.x

    authors: Sugai T,Takagi T,Yamamoto S,Takahashi Y

    更新日期:1979-12-01 00:00:00

  • Fragrances and other materials in deodorants: search for potentially sensitizing molecules using combined GC-MS and structure activity relationship (SAR) analysis.

    abstract::Deodorants are one of the most frequently-used types of cosmetics and are a source of allergic contact dermatitis. Therefore, a gas chromatography - mass spectrometric analysis of 71 deodorants was performed for identification of fragrance and non-fragrance materials present in marketed deodorants. Futhermore, the sen...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1998.tb05944.x

    authors: Rastogi SC,Lepoittevin JP,Johansen JD,Frosch PJ,Menné T,Bruze M,Dreier B,Andersen KE,White IR

    更新日期:1998-12-01 00:00:00

  • p-Phenylenediamine exposure in real life - a case-control study on sensitization rate, mode and elicitation reactions in the northern Netherlands.

    abstract:BACKGROUND:The prevalence of p-phenylenediamine (PPD) sensitization is 4% in the patch tested population and varies between zero and 1.5% in the general population. Hair dye is a recognised sensitization source. OBJECTIVES:To define the prevalence rates of PPD sensitization in the general and patch tested populations ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.12354

    authors: Vogel TA,Coenraads PJ,Bijkersma LM,Vermeulen KM,Schuttelaar ML,EDEN Fragrance Study Group.

    更新日期:2015-06-01 00:00:00

  • Characteristics of chromium-allergic dermatitis patients prior to regulatory intervention for chromium in leather: a questionnaire study.

    abstract:BACKGROUND:Chromium-tanned leather articles currently constitute the most important cause of contact allergy to chromium in Denmark. A regulation on the content of hexavalent chromium in leather was adopted in November 2013 by the EU member states. OBJECTIVES:To characterize patients with chromium allergy and their di...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.12291

    authors: Bregnbak D,Thyssen JP,Zachariae C,Johansen JD

    更新日期:2014-12-01 00:00:00

  • Histological changes in rabbits after application of medicaments and cosmetic bases (III).

    abstract::An experimental study is reported of the irritant potential of oil of purcellin , isopropyl palmitate, nonyl phenol, Modulan , Amerchol and Acetulan when massaged in fixed amounts into the rabbit's skin daily for 30 days. Skin biopsies provided data on the number of epithelial cell layers, cell counts of the superfici...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1984.tb00102.x

    authors: Rantuccio F,Sinisi D,Coviello C,Conte A,Scardigno A

    更新日期:1984-04-01 00:00:00

  • Filaggrin loss-of-function mutations and atopic dermatitis as risk factors for hand eczema in apprentice nurses: part II of a prospective cohort study.

    abstract:BACKGROUND/OBJECTIVES:Environmental exposure and personal susceptibility both contribute to the development of hand eczema. In this study, we investigated the effect of loss-of-function mutations in the filaggrin gene (FLG), atopic dermatitis and wet work exposure on the development of hand eczema in apprentice nurses....

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.12139

    authors: Visser MJ,Verberk MM,Campbell LE,McLean WH,Calkoen F,Bakker JG,van Dijk FJ,Bos JD,Kezic S

    更新日期:2014-03-01 00:00:00

  • Occupational allergic contact dermatitis from cinnamon including one case from airborne exposure.

    abstract:BACKGROUND:The bark of the cinnamon tree is used as a spice; its flavour is from an essential oil containing mainly cinnamal. OBJECTIVE:To report new cases of occupational allergic contact dermatitis (ACD) from cinnamon and a novel case of airborne cinnamon contact allergy. METHODS:We examined the patient material of...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2008.01486.x

    authors: Ackermann L,Aalto-Korte K,Jolanki R,Alanko K

    更新日期:2009-02-01 00:00:00