Abstract:
BACKGROUND:An inverse relationship between disease severity and health-related quality of life (HR-QoL) in patients with hand eczema is well established, but modifying effects of demographic variables have been less well studied. OBJECTIVE:To identify the influence of metropolitan versus non-metropolitan residence on the relationship between disease severity and HR-QoL in patients with occupational hand eczema. METHODS:The city of Copenhagen and the rest of Zealand were defined as metropolitan and non-metropolitan areas, respectively. Participants were 773 persons with occupational hand eczema. A questionnaire on the severity of hand eczema and HR-QoL was sent to all participants. RESULTS:The odds for reporting moderate to high severity of occupational hand eczema were significantly lower in the metropolitan population than in the non-metropolitan population [odds ratio (OR): 0.42; 95%CI: 0.23-0.75], whereas low dermatology-related quality of life was more prevalent in metropolitan than in non-metropolitan patients (OR: 1.31; 95%CI: 0.83-2.05), indicating that hand eczema had a more pronounced negative effect in metropolitan patients, in spite of less severe eczema. CONCLUSION:Our data indicate that area of residence has a modifying effect on the relationship between disease severity and HR-QoL, with a more negative impact on HR-QoL in metropolitan than in non-metropolitan areas. This information is important with respect to fully appreciating the burden of occupational hand eczema.
journal_name
Contact Dermatitisjournal_title
Contact dermatitisauthors
Nørreslet LB,Agner T,Sørensen JA,Ebbehøj NE,Bonde JP,Fisker MHdoi
10.1111/cod.12962subject
Has Abstractpub_date
2018-05-01 00:00:00pages
348-354issue
5eissn
0105-1873issn
1600-0536journal_volume
78pub_type
杂志文章abstract:BACKGROUND:The former 'EU Nickel Directive' and, since 2009, the REACH Regulation (item 27 of Annex XVII) do not include all metallic objects. The nickel content of tools is not regulated by the REACH Regulation, even if they may come into in prolonged contact with the skin. Tools might be possible sources of nickel an...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/cod.12462
更新日期:2015-11-01 00:00:00
abstract::Development of local allergic reactions after different application times with Finn Chambers was recorded in 34 nickel-sensitive patients. Biologically significant amounts of nickel seemed to penetrate the skin within a few hours, although physical penetration was minimal. Nickel was detected only in the upper keratin...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1985.tb01131.x
更新日期:1985-05-01 00:00:00
abstract:BACKGROUND:The widespread use of fragrance-containing products is probably the most important reason for its high impact in allergic contact dermatitis. OBJECTIVES:To describe the frequency of contact allergy to fragrance allergens as tested in the standard series, in relation to age, sex and lesion locations. To dete...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.2007.01287.x
更新日期:2008-03-01 00:00:00
abstract:BACKGROUND:Contact urticaria (CU) and protein contact dermatitis (PCD) are mainly induced by an immediate, IgE-mediated immunological mechanism. Immediate sensitization is also linked to asthma and/or allergic rhinitis. OBJECTIVES:To report causes of work-induced CU and PCD, and to evaluate the occurrence of concomita...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/cod.12856
更新日期:2017-12-01 00:00:00
abstract::Deodorized kerosene in a concentration of 50 g/100 g in pet. did not cause cutaneous inflammation in 10 control guinea pigs. The proportion of 19 guinea pigs exhibiting inflammation following exposure to deodorized kerosene in the guinea pig maximization test increased, but the increase was not significant. The respon...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1983.tb04459.x
更新日期:1983-11-01 00:00:00
abstract::Pimecrolimus suppresses the proinflammatory cytokine production of cutaneous T and mast cells (1). It is used to treat atopic dermatitis and is the active ingredient in the topical formulation pimecrolimus 1.0% cream (Elidel, Novartis Pharma AG, Basel, Switzerland). ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.2007.00822.x
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Contact allergy to phenol-formaldehyde resins (PFRs) based on phenol and formaldehyde is not detected by a p-tertiary-butylphenol-formaldehyde resin (PTBP-FR) included in most baseline patch test series. OBJECTIVES:To investigate the rate of contact allergy to PFR-2 (a mixture of monomers and dimers from a ...
journal_title:Contact dermatitis
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1600-0536.2011.01921.x
更新日期:2011-07-01 00:00:00
abstract::Data suggests that protection from gloves is paradoxically reduced because of effects of occlusion on the skin. The aim of this study was to characterize these effects on physical and functional properties of stratum corneum. Volunteer trials were conducted using patches of polyvinyl chloride (PVC) glove material on t...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1995.tb00542.x
更新日期:1995-09-01 00:00:00
abstract::The epidermal response to 2 different irritants, nonanoic acid (NAA) and sodium lauryl sulfate (SLS), was investigated with 2 different methods. NAA 80% and SLS 4% were applied under occlusion for up to 24 h. Elemental changes were determined in cryosections by x-ray microanalysis. Compared to unexposed skin a signifi...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1996.tb02416.x
更新日期:1996-12-01 00:00:00
abstract::A way of adapting a treatment room for patch test purposes is described. ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1975.tb05362.x
更新日期:1975-06-01 00:00:00
abstract::Several factors may be responsible for stomatitis in general and the burning mouth syndrome in particular. The results of patch testing are reported in 4 patients with burning mouth symptoms thought to be due to sensitization to denture material. 2 patients reacted to substances in Luxene dentures, but the allergens w...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1988.tb02748.x
更新日期:1988-02-01 00:00:00
abstract:BACKGROUND:Fragrance contact allergy has for long been recognized as an important health issue. In Denmark, the frequency of fragrance mix (FM) I contact allergy increased between 1985-1986 and 1997-1998 among male and female dermatitis patients. OBJECTIVES:To investigate the development of FM I and Myroxylon pereirae...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.2008.01418.x
更新日期:2008-10-01 00:00:00
abstract::Occupational allergic contact dermatitis from metallic mercury is rare. Here we present the only 2 patients with relevant occupational mercury allergy detected at our clinic since 1974. The first patient was a dental nurse who became sensitized to metallic mercury from amalgam when handling uncured amalgam without pro...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1993.tb03319.x
更新日期:1993-01-01 00:00:00
abstract::It has been known since the 1940s that nail polishes contain allergenic ingredients. The aim of this study was to clarify whether the nail polishes on the market today contain significant amounts of allergens, and what the solvents are. The following ingredients were determined: toluene, toluene sulfonamide formaldehy...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1997.tb00189.x
更新日期:1997-10-01 00:00:00
abstract::Several acetogenins, characteristic of the Annonaceae, have been found to exhibit pesticidal and feeding-deterrent activities against a variety of pests and are undergoing commercial development as pesticides. The sensitizing potential of one of these plants, pawpaw, Asimina triloba Dunal, was examined in the current ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1993.tb04533.x
更新日期:1993-07-01 00:00:00
abstract::Allergic contact dermatitis caused by medical devices for diabetes patients has been increasingly described in the literature in the last few years. This article reviews the cases of allergic contact dermatitis caused by insulin pumps and glucose sensors reported since the 1970s, the culprit allergen(s), the results o...
journal_title:Contact dermatitis
pub_type: 杂志文章,评审
doi:10.1111/cod.13120
更新日期:2018-12-01 00:00:00
abstract::A relationship between sensitivity to poison oak or poison ivy and mango dermatitis has been suggested by previous publications. The observation that acute allergic contact dermatitis can arise on first exposure to mango in patients who have been sensitized beforehand by contact with other urushiol-containing plants h...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.0105-1873.2005.00454.x
更新日期:2005-01-01 00:00:00
abstract::Investigations on light reactions in a patient with vitiligo are presented. The minimal erythema dose (MED) in the UVB area was approximately 1/3 of that in persons of skin type II. The application of furocoumarins (psoralens) increased light tolerance by 1 MED at 300-310 nm. Action spectrum studies with furocoumarins...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1983.tb04429.x
更新日期:1983-09-01 00:00:00
abstract::Adverse cutaneous reactions to topically applied olive oil are seldom reported, and positive patch tests to it are mostly regarded as allergic. To evaluate such "positive" patch test reactions, 77 female (mean age: 44 years) and 23 male eczema patients (mean age: 46 years) were prospectively patch tested with freshly ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1997.tb00914.x
更新日期:1997-01-01 00:00:00
abstract::Surface-active agents (surfactants) are characterized by the possession of 2 different moieties, both polar and non-polar regions on the same molecule. Surfactants are broadly classified as anionic, cationic, amphoteric, or non-ionic, according to the nature of the hydrophile yielded in aqueous solution. In currently ...
journal_title:Contact dermatitis
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0536.1995.tb00470.x
更新日期:1995-10-01 00:00:00
abstract:BACKGROUND:Contact allergy to rubber additives is common, particularly in patients with occupational dermatitis. OBJECTIVES:To descriptively analyse and compare patch test reactions in patients patch tested both with the baseline series and with an additional 'rubber series' as used in the department. METHODS:Patch t...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/cod.12651
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:Hyperkeratotic hand eczema (HHE) is a typical clinical hand eczema subtype with a largely unknown pathophysiology. OBJECTIVE:To investigate histopathology, expression of keratins (K), epidermal barrier proteins, and adhesion molecules in HHE. METHODS:Palmar skin biopsies (lesional and perilesional) were ob...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/cod.13572
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND:Thaumetopoea pityocampa [pine processionary moth (PPM)] is one of the most important lepidopteran agents causing urticant cutaneous reactions in humans in Mediterranean countries. This species is also expanding northwards, because of global warming. OBJECTIVES:To investigate the prevalence, distribution by ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.2011.01884.x
更新日期:2011-04-01 00:00:00
abstract::The consequences of a diagnosis of occupational contact dermatitis (OCD) were investigated using cases available from the voluntary surveillance scheme, EPIDERM. Cases of OCD reported from November 1994 to September 1995 were identified and sampled to give at least 100 cases of allergic, irritant and mixed OCD reporte...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1034/j.1600-0536.2002.460505.x
更新日期:2002-05-01 00:00:00
abstract:BACKGROUND:There are no Indian studies on the association between filaggrin gene (FLG) mutations and any dermatosis, including hand eczema. OBJECTIVES:To determine the prevalence of FLG mutations in Indian hand eczema patients, and examine associations between such mutations and any aetiological type of hand eczema. ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/cod.13233
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:On skin contact, nickel accumulates in the stratum corneum, where it is probably bound to proteins and amino acids. One probable contributor is filaggrin, which binds nickel avidly. Filaggrin gene (FLG) null mutations lead to a complete lack of filaggrin production from the affected allele, and have been ass...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/cod.12228
更新日期:2014-07-01 00:00:00
abstract::A chemical operator handling dimethyl acetylenedicarboxylate (DMAD) developed delayed and pain-free burns on one of his feet 2 days after a supposed spillage of DMAD. The injuries were confirmed to be associated with DMAD by chemical analysis of the operator's safety boot and patch tests. DMAD easily penetrates some p...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1984.tb00166.x
更新日期:1984-07-01 00:00:00
abstract::The purpose of the present study was to compare the frequency of lanolin allergy during two periods and to assess the adequacy of testing with one standard allergen. Among 1230 consecutive patients with eczema who were standard patch tested, 33 (2.7%), 21 females and 12 males, gave a positive reaction to wool alcohols...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1979.tb04824.x
更新日期:1979-05-01 00:00:00
abstract:BACKGROUND:Workers exposed to epoxy products are at risk of developing allergic contact dermatitis. OBJECTIVES:To compare workers throughout the German construction industry with and without skin allergy to epoxy resins, hardeners, and/or reactive diluents, and to investigate which determinants are related to the deve...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/cod.12529
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND:Foot eczema often occurs in combination with hand eczema. However, in contrast to the situation with hand eczema, knowledge about foot eczema is scarce, especially in occupational settings. OBJECTIVE:To evaluate the prevalence of foot eczema and associated factors in patients with hand eczema taking part in...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/cod.12370
更新日期:2015-08-01 00:00:00