听力与言语-语言病理学

行为科学

医学伦理学

你正在浏览Cardiovascular Toxicology期刊下所有文献
  • Validation of Corrected and Dispersed QT as Predictors of Adverse Outcomes in Acute Cardiotoxicities.

    abstract::Acute cardiovascular poisoning is a major cause of adverse outcomes in poisoning emergencies. The prognostic validity of corrected QT (QTc) and dispersed QT (QTd) in these outcomes is still limited. The present study aimed to determine the risk factors of mortality, adverse cardiovascular events (ACVE), and intensive ...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-020-09629-8

    authors: El-Sarnagawy GN,Shaban AE,Lashin HI

    更新日期:2021-01-05 00:00:00

  • Massive β1-Adrenergic Receptor Reaction Explains Irreversible Acute Arrhythmia in a Fatal Case of Acute Pure Caffeine Intoxication.

    abstract::Caffeine, a naturally occurring purine-based alkaloid, is the most consumed psychostimulant worldwide. Since caffeine pharmacokinetics shows extreme interindividual variability, it is not easy to establish its toxic dose. Only a few cases of death due to acute caffeine intoxication have been described so far, the majo...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-020-09608-z

    authors: Maiese A,La Russa R,Del Fante Z,Turillazzi E,David MC,Frati P,Fineschi V

    更新日期:2021-01-01 00:00:00

  • M3, a 1,4-Dihydropyridine Derivative and Mixed L-/T-Type Calcium Channel Blocker, Attenuates Isoproterenol-Induced Toxicity in Male Wistar Rats.

    abstract::Recent evidence indicates that Ca2+ dysregulation is involved in the pathogenesis of isoproterenol (ISP)-induced biochemical toxicity and associated oxidative stress. In this study, we investigated the chemopreventive benefit of M3, a 1,4-dihydropyridine calcium channel blocker, against ISP-induced toxicity in male Wi...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-020-09587-1

    authors: Kale OE,Gündüz MG,Ogunbiyi BT,Ogundare TF,Ekor M,Awodele O

    更新日期:2020-12-01 00:00:00

  • Central Blockade of E-Prostanoid 3 Receptor Ameliorated Hypertension Partially by Attenuating Oxidative Stress and Inflammation in the Hypothalamic Paraventricular Nucleus of Spontaneously Hypertensive Rats.

    abstract::Hypertension, as one of the major risk factors for cardiovascular disease, significantly affects human health. Prostaglandin E2 (PGE2) and the E3-class prostanoid (EP3) receptor have previously been demonstrated to modulate blood pressure and hemodynamics in various animal models of hypertension. The PGE2-evoked press...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-020-09619-w

    authors: Wang FF,Ba J,Yu XJ,Shi XL,Liu JJ,Liu KL,Fu LY,Su Q,Li HB,Kang KB,Yi QY,Wang SQ,Gao HL,Qi J,Li Y,Zhu GQ,Kang YM

    更新日期:2020-11-09 00:00:00

  • Involvement of ROS/NLRP3 Inflammasome Signaling Pathway in Doxorubicin-Induced Cardiotoxicity.

    abstract::Doxorubicin (Dox) is widely used in cancer therapy, but the clinical application is limited by its cardiotoxicity. The underlying mechanism of Dox-induced cardiotoxicity remains unclear. Present study aimed to evaluate the role of NLRP3 inflammasome in Dox-induced cardiotoxicity. The NLRP3 inflammasome was activated i...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-020-09576-4

    authors: Wei S,Ma W,Li X,Jiang C,Sun T,Li Y,Zhang B,Li W

    更新日期:2020-10-01 00:00:00

  • Oleic Acid Protects from Arsenic-Induced Cardiac Hypertrophy via AMPK/FoxO/NFATc3 Pathway.

    abstract::Arsenic toxicity is one of the major environmental problems causing various diseases, cardiovascular disorders is one of them. Several epidemiological studies have shown that arsenic causes cardiac hypertrophy but the detailed molecular mechanism is to be studied yet. This study is designed to determine the molecules ...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-019-09550-9

    authors: Samanta J,Mondal A,Saha S,Chakraborty S,Sengupta A

    更新日期:2020-06-01 00:00:00

  • The Protective Effect of Crataegus aronia Against High-Fat Diet-Induced Vascular Inflammation in Rats Entails Inhibition of the NLRP-3 Inflammasome Pathway.

    abstract::This study investigated whether the whole-plant aqueous extract of Crataegus aronia (C. aronia) could protect against or alleviate high-fat diet (HFD)-induced aortic vascular inflammation in rats by inhibiting the NLRP-3 inflammasome pathway and examined some mechanisms of action with respect to its antioxidant and hy...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-019-09534-9

    authors: Shatoor AS,Al Humayed S

    更新日期:2020-02-01 00:00:00

  • MDMA Induced Cardio-toxicity and Pathological Myocardial Effects: A Systematic Review of Experimental Data and Autopsy Findings.

    abstract::3,4-Methylenedioxymethamphetamine (MDMA), more commonly known as "ecstasy," is a semi-synthetic entactogenic phenylethylamine. In recent years it has gained popularity as a recreational drug whose use has registered an upward trend especially among adolescents and young adults. Despite its unwarranted reputation of be...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-019-09526-9

    authors: Bonsignore A,Barranco R,Morando A,Fraternali Orcioni G,Ventura F

    更新日期:2019-12-01 00:00:00

  • The Use of iPSC-Derived Cardiomyocytes and Optical Mapping for Erythromycin Arrhythmogenicity Testing.

    abstract::Erythromycin is an antibiotic that prolongs the QT-interval and causes Torsade de Pointes (TdP) by blocking the rapid delayed rectifying potassium current (IKr) without affecting either the slow delayed rectifying potassium current (IKs) or inward rectifying potassium current (IK1). Erythromycin exerts this effect in ...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-019-09532-x

    authors: Podgurskaya AD,Tsvelaya VA,Slotvitsky MM,Dementyeva EV,Valetdinova KR,Agladze KI

    更新日期:2019-12-01 00:00:00

  • Acylated Ghrelin Protects the Hearts of Rats from Doxorubicin-Induced Fas/FasL Apoptosis by Stimulating SERCA2a Mediated by Activation of PKA and Akt.

    abstract::This study investigated if the cardioprotective effect of acylated ghrelin (AG) against doxorubicin (DOX)-induced cardiac toxicity in rats involves inhibition of Fas/FasL-mediated cell death. It also investigated if such an effect is mediated by restoring Ca+2 homeostasis from the aspect of stimulation of SERCA2a rece...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-019-09527-8

    authors: Shati AA,Dallak M

    更新日期:2019-12-01 00:00:00

  • Effect of Gestational Age on Maternofetal Vascular Function Following Single Maternal Engineered Nanoparticle Exposure.

    abstract::Normal pregnancy outcome is accomplished, in part, by rapid and expansive physiological adaptations to the systemic circulation, the extent of which is specific to gestational day (GD) and anatomical location. Pregnancy-related hemodynamic changes in uterine placental blood flow stimulate compensatory vascular signali...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-019-09505-0

    authors: Fournier SB,Kallontzi S,Fabris L,Love C,Stapleton PA

    更新日期:2019-08-01 00:00:00

  • Vildagliptin, an Anti-diabetic Drug of the DPP-4 Inhibitor, Induces Vasodilation via Kv Channel and SERCA Pump Activation in Aortic Smooth Muscle.

    abstract::This study investigated vildagliptin-induced vasodilation and its related mechanisms using phenylephrine induced precontracted rabbit aortic rings. Vildagliptin induced vasodilation in a concentration-dependent manner. Pretreatment with the large-conductance Ca2+-activated K+ channel blocker paxilline, ATP-sensitive K...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-018-9496-5

    authors: Seo MS,Li H,An JR,Jung ID,Jung WK,Ha KS,Han ET,Hong SH,Choi IW,Park WS

    更新日期:2019-06-01 00:00:00

  • An Overview on Arsenic Trioxide-Induced Cardiotoxicity.

    abstract::Arsenic trioxide (ATO) is among the first-line chemotherapeutic drugs used in oncological practice. It has shown substantial efficacy in treating patients with relapsed or refractory acute promyelocytic leukaemia. The clinical use of ATO is hampered due to cardiotoxicity and hence many patients are precluded from rece...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章,评审

    doi:10.1007/s12012-018-09504-7

    authors: Vineetha VP,Raghu KG

    更新日期:2019-04-01 00:00:00

  • Analysis of Safety Margin of Lithium Carbonate Against Cardiovascular Adverse Events Assessed in the Halothane-Anesthetized Dogs.

    abstract::Lithium is one of the classical drugs that have been widely used for treating bipolar disorder. However, several cardiac side effects including sick sinus syndrome, bundle branch block, ventricular tachycardia/fibrillation, non-specific T-wave abnormalities in addition to Brugada-type electrocardiographic changes have...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-018-9464-0

    authors: Goto A,Nakamura Y,Lubna NJ,Chiba K,Hagiwara-Nagasawa M,Izumi-Nakaseko H,Ando K,Naito AT,Sugiyama A

    更新日期:2018-12-01 00:00:00

  • On the Efficacy of Cardio-Pulmonary Resuscitation and Epinephrine Following Cyanide- and H2S Intoxication-Induced Cardiac Asystole.

    abstract::This study was aimed at determining the efficacy of epinephrine, followed by chest compressions, in producing a return of spontaneous circulation (ROSC) during cyanide (CN)- or hydrogen sulfide (H2S)-induced toxic cardiac pulseless electrical activity (PEA) in the rat. Thirty-nine anesthetized rats were exposed to eit...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-018-9454-2

    authors: Judenherc-HaouzI A,Sonobe T,Bebarta VS,Haouzi P

    更新日期:2018-10-01 00:00:00

  • Clopidogrel Pharmacogenetics in Iranian Patients Undergoing Percutaneous Coronary Intervention.

    abstract::Clopidogrel is used in patients with coronary syndromes and at risk of thrombotic events or receiving percutaneous coronary intervention (PCI) for reducing heart attack and stroke. Here we present genotype and phenotype study of Iranian patients undergoing PCI treated with clopidogrel during a 6-month period of follow...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-018-9459-x

    authors: Mahdieh N,Rabbani A,Firouzi A,Zahedmehr A,Hoseinimoghaddam M,Saedi S,Sanati H,Basiri H,Noohi F,Rabbani B,Maleki M

    更新日期:2018-10-01 00:00:00

  • Characteristics of Cobalt-Related Cardiomyopathy in Metal Hip Implant Patients: An Evaluation of 15 Published Reports.

    abstract::Over 300,000 hip replacements occurred in the USA in 2010, and the frequency is likely increasing annually. Blood Cobalt (Co) concentrations in patients with well-functioning cobalt-chromium (Co-Cr) hip implants are usually elevated above background concentrations relative to the general population. Excessive Co expos...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章,评审

    doi:10.1007/s12012-017-9433-z

    authors: Fung ES,Monnot A,Kovochich M,Unice KM,Tvermoes BE,Galbraith D,Finley BL,Paustenbach DJ

    更新日期:2018-06-01 00:00:00

  • Asiatic Acid Ameliorates Doxorubicin-Induced Cardiac and Hepato-Renal Toxicities with Nrf2 Transcriptional Factor Activation in Rats.

    abstract::Asiatic acid (AA), a pentacyclic triterpenoid, is a key phytoconstituent of Centella asiatica. AA is a patented as a cytotoxic substance, and it exerts cytotoxicity against Hep3B, Hela and MCF-7 cell lines. However, pentacyclic triterpenoids also modulate the expression and transcriptional activities of Nrf2 and exert...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-017-9424-0

    authors: Kamble SM,Patil CR

    更新日期:2018-04-01 00:00:00

  • Effects of Remifentanil Pretreatment on Bupivacaine Cardiotoxicity in Rats.

    abstract::Unintentional intravascular administration of bupivacaine may cause local anesthetic systemic toxicity (LAST). Although many systems are affected in LAST, the cardiovascular effects can be life-threatening. Remifentanil is a selective, ultra-short-acting, µ-opioid receptor agonist opioid. This study assessed the effec...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-017-9413-3

    authors: Pişkin Ö,Ayoğlu H

    更新日期:2018-02-01 00:00:00

  • Role of Peroxynitrite-Induced Activation of Poly(ADP-Ribose) Polymerase (PARP) in Circulatory Shock and Related Pathological Conditions.

    abstract::Peroxynitrite is a powerful oxidant, formed from the reaction of nitric oxide and superoxide. It is known to interact and modify different biological molecules such as DNA, lipids and proteins leading to alterations in their structure and functions. These events elicit various cellular responses, including cell signal...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章,评审

    doi:10.1007/s12012-016-9394-7

    authors: Islam BU,Habib S,Ali SA,Moinuddin,Ali A

    更新日期:2017-10-01 00:00:00

  • Dofetilide in Overdose: A Case Series from Poison Center Data.

    abstract::Dofetilide is a class III antiarrhythmic used for treating atrial dysrhythmias. Though its adverse effects are well described in routine use, very little is known about dofetilide toxicity in overdose. This is a retrospective case series of consecutive patients reported to our poison center after dofetilide overdose. ...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-016-9384-9

    authors: Hieger MA,Maskell KF,Moss MJ,Powell SW,Cumpston KL

    更新日期:2017-07-01 00:00:00

  • Assessment of Safety Margin of an Antipsychotic Drug Haloperidol for Torsade de Pointes Using the Chronic Atrioventricular Block Dogs.

    abstract::Since an antipsychotic drug haloperidol has been clinically reported to induce QT interval prolongation and torsade de pointes, in this study its risk stratification for the onset of torsade de pointes was performed by using the chronic atrioventricular block canine model with a Holter electrocardiogram. Haloperidol i...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-016-9388-5

    authors: Izumi-Nakaseko H,Nakamura Y,Cao X,Wada T,Ando K,Sugiyama A

    更新日期:2017-07-01 00:00:00

  • The Correlation Between 9p21 Chromosome rs4977574 Polymorphism Genotypes and the Development of Coronary Artery Heart Disease.

    abstract::Our aim is to investigate the correlation between 9p21 chromosome rs4977574 polymorphism genotypes and the development of coronary artery heart disease (CHD). Two hundred and eighty-nine patients with angiography-confirmed CHD were recruited as the CHD group, while 338 subjects without CHD symptoms were enrolled as th...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-016-9372-0

    authors: Tang O,Lv J,Cheng Y,Qin F

    更新日期:2017-04-01 00:00:00

  • Rutin Attenuates Carfilzomib-Induced Cardiotoxicity Through Inhibition of NF-κB, Hypertrophic Gene Expression and Oxidative Stress.

    abstract::Carfilzomib is a proteasome inhibitor, commonly used in multiple myeloma, but its clinical use may be limited due to cardiotoxicity. This study was aimed to evaluate the influence of rutin in carfilzomib-induced cardiotoxicity in rats. Wistar albino male rats weighing 200-250 g (approximately 10 weeks old) were taken ...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-015-9356-5

    authors: Imam F,Al-Harbi NO,Al-Harbia MM,Korashy HM,Ansari MA,Sayed-Ahmed MM,Nagi MN,Iqbal M,Khalid Anwer M,Kazmi I,Afzal M,Bahashwan S

    更新日期:2017-01-01 00:00:00

  • Cardioprotective and Anti-arrhythmic Effects of Magnesium Pretreatment Against Ischaemia/Reperfusion Injury in Isoprenaline-Induced Hypertrophic Rat Heart.

    abstract::The effects of magnesium (Mg2+) on ischaemic complications of pathological cardiac hypertrophy are unclear. In this study, we investigated effects of Mg2+ pretreatment on ischaemia/reperfusion (I/R) injury in isoprenaline (ISO)-induced hypertrophic hearts. Wistar rats were treated for 7 days with different combination...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-015-9355-6

    authors: Amoni M,Kelly-Laubscher R,Petersen M,Gwanyanya A

    更新日期:2017-01-01 00:00:00

  • NF-κB Blockade in Hypothalamic Paraventricular Nucleus Inhibits High-Salt-Induced Hypertension Through NLRP3 and Caspase-1.

    abstract::High-salt-induced inflammation and oxidative stress in the hypothalamic paraventricular nucleus (PVN) contribute to the pathogenesis of salt-sensitive hypertension. In this study, we hypothesized that chronic inhibition of nuclear factor-κB (NF-κB) activity in the PVN delays the progression of hypertension by upregula...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-015-9344-9

    authors: Qi J,Yu XJ,Shi XL,Gao HL,Yi QY,Tan H,Fan XY,Zhang Y,Song XA,Cui W,Liu JJ,Kang YM

    更新日期:2016-10-01 00:00:00

  • Paraventricular Nucleus Infusion of Epigallocatechin-3-O-Gallate Improves Renovascular Hypertension.

    abstract::Oxidative stress plays an important role in the pathogenesis of hypertension. Epigallocatechin-3-O-gallate (EGCG) is the main polyphenol present in green tea and is known for its potent antioxidant and anti-inflammatory properties. In the present study, we hypothesize that EGCG attenuates oxidative stress in the parav...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-015-9335-x

    authors: Yi QY,Qi J,Yu XJ,Li HB,Zhang Y,Su Q,Shi T,Zhang DM,Guo J,Feng ZP,Wang ML,Zhu GQ,Liu JJ,Shi XL,Kang YM

    更新日期:2016-07-01 00:00:00

  • Cardiac Fas-Dependent and Mitochondria-Dependent Apoptotic Pathways in a Transgenic Mouse Model of Huntington's Disease.

    abstract::Huntington's disease is an autosomal dominant neurodegenerative disease caused by a CAG repeat expansion in the huntingtin gene. Heart disease is the second leading cause of death in patients with Huntington's disease. This study was to evaluate whether cardiac Fas-dependent and mitochondria-dependent apoptotic pathwa...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-015-9318-y

    authors: Wu BT,Chiang MC,Tasi CY,Kuo CH,Shyu WC,Kao CL,Huang CY,Lee SD

    更新日期:2016-04-01 00:00:00

  • Subclinical Myocardial Impairment Occurred in Septal and Anterior LV Wall Segments After Anthracycline-Embedded Chemotherapy and did not Worsen During Adjuvant Trastuzumab Treatment in Breast Cancer Patients.

    abstract::In a previous study of breast cancer patients, we found changes in cardiac function and size during the early stages of adjuvant trastuzumab (Herceptin(®)) therapy. Here we present a subgroup analysis of this patient cohort. This subgroup received a anthracycline-embedded chemotherapy followed by at least 3 months up ...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-015-9328-9

    authors: Lange SA,Jung J,Jaeck A,Hitschold T,Ebner B

    更新日期:2016-04-01 00:00:00

  • Synchronization in the Heart Rate and the Vasomotion in Rat Aorta: Effect of Arsenic Trioxide.

    abstract::Arsenic trioxide (As2O3) is used clinically in the management of acute promyelocytic leukemia, and the use of electrocardiogram (ECG) in this management is important as arsenic use may cause distortion of the electrical properties with its attendant sequel. We studied the effect of As2O3 on vasomotion in rat aortic ri...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-015-9312-4

    authors: Cifuentes F,Palacios J,Nwokocha CR

    更新日期:2016-01-01 00:00:00

  • Comparative Investigation of Protective Effects of Metyrosine and Metoprolol Against Ketamine Cardiotoxicity in Rats.

    abstract::This study investigated the effect of metyrosine against ketamine-induced cardiotoxicity in rats and compared the results with the effect of metoprolol. In this study, rats were divided into groups A, B and C. In group A, we investigated the effects of a single dose of metyrosine (150 mg/kg) and metoprolol (20 mg/kg) ...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-014-9301-z

    authors: Ahiskalioglu A,Ince I,Aksoy M,Ahiskalioglu EO,Comez M,Dostbil A,Celik M,Alp HH,Coskun R,Taghizadehghalehjoughi A,Suleyman B

    更新日期:2015-10-01 00:00:00

  • Epigenetic regulation of cardiac myofibril gene expression during heart development.

    abstract::Cardiac gene expression regulation is controlled not only by genetic factors but also by environmental, i.e., epigenetic factors. Several environmental toxic effects such as oxidative stress and ischemia can result in abnormal myofibril gene expression during heart development. Troponin, one of the regulatory myofibri...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-014-9278-7

    authors: Zhao W,Liu L,Pan B,Xu Y,Zhu J,Nan C,Huang X,Tian J

    更新日期:2015-07-01 00:00:00

  • Platinum Complexes-Induced Cardiotoxicity of Isolated, Perfused Rat Heart: Comparison of Pt(II) and Pt(IV) Analogues Versus Cisplatin.

    abstract::We have compared the cardiotoxicity of five platinum complexes in a model of isolated rat heart using the Langendorff technique. These effects were assessed via coronary flow (CF) and cardiac functional parameters. cis-Diamminedichloroplatinum(II) (cisplatin, CDDP), dichloro-(1,2-diaminocyclohexane)platinum(II) (Pt((I...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-014-9293-8

    authors: Misic MM,Jakovljevic VL,Bugarcic ZD,Zivkovic VI,Srejovic IM,Barudzic NS,Djuric DM,Novokmet SS

    更新日期:2015-07-01 00:00:00

  • Glyphosate-based herbicides potently affect cardiovascular system in mammals: review of the literature.

    abstract::In glyphosate (G)-based herbicides (GBHs), the declared active principle G is mixed with several adjuvants that help it to penetrate the plants' cell membranes and its stabilization and liposolubility. Its utilization is growing with genetically modified organisms engineered to tolerate GBH. Millions of farmers suffer...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章,评审

    doi:10.1007/s12012-014-9282-y

    authors: Gress S,Lemoine S,Séralini GE,Puddu PE

    更新日期:2015-04-01 00:00:00

  • Creatine supplementation reduces doxorubicin-induced cardiomyocellular injury.

    abstract::Heart failure is a common complication of doxorubicin (DOX) therapy. Previous studies have shown that DOX adversely impacts cardiac energy metabolism, and the ensuing energy deficiencies antedate clinical manifestations of cardiac toxicity. Brief exposure of cultured cardiomyocytes to DOX significantly decreases creat...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-014-9283-x

    authors: Santacruz L,Darrabie MD,Mantilla JG,Mishra R,Feger BJ,Jacobs DO

    更新日期:2015-04-01 00:00:00

  • Cardiovascular effects of Phaleria macrocarpa extracts combined with mainstay FAC regimen for breast cancer.

    abstract::DLBS1425 is a bioactive compound extracted from Phaleria macrocarpa, with anti-proliferative, anti-inflammatory and anti-angiogenic properties against cancer cells. The present study was aimed to assess cardiotoxicity of DLBS1425, compared to the mainstay regimen for breast cancer, 5-fluorouracil:doxorubicin:cyclophos...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-014-9275-x

    authors: Anggadiredja K,Tjandrawinata RR

    更新日期:2015-01-01 00:00:00

  • Sudden cardiac death in young adult.

    abstract::Cardiovascular disease represents one of the most important public health problem in the Western countries, with sudden cardiac death (SCD) being the most common cause of death in adults under 65 years of age. The objective of the present study is to evaluate the leading causes of SCD in young adults who died suddenly...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-014-9255-1

    authors: Silva AC,Santos L,Dinis-Oliveira RJ,Magalhães T,Santos A

    更新日期:2014-12-01 00:00:00

  • The adverse cardiac effects of Di(2-ethylhexyl)phthalate and Bisphenol A.

    abstract::The ubiquitous nature of plastics has raised concerns pertaining to continuous exposure to plastic polymers and human health risks. Of particular concern is the use of endocrine-disrupting chemicals in plastic production, including di(2-ethylhexyl)phthalate (DEHP) and bisphenol A (BPA). Widespread and continuous expos...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章,评审

    doi:10.1007/s12012-014-9258-y

    authors: Posnack NG

    更新日期:2014-12-01 00:00:00

  • Intracellular Ca(2+) overload induced by extracellular Ca(2+) entry plays an important role in acute heart dysfunction by tentacle extract from the jellyfish Cyanea capillata.

    abstract::The exact mechanism of acute heart dysfunction caused by jellyfish venom remains unclear for the moment. In the present study, we examined the problem caused by the tentacle extract (TE) from the jellyfish Cyanea capillata at the levels of whole animal, isolated heart, primarily cultured cardiomyocytes, and intracellu...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-014-9250-6

    authors: Zhang L,He Q,Wang Q,Zhang B,Wang B,Xu F,Wang T,Xiao L,Zhang L

    更新日期:2014-09-01 00:00:00

  • Preventive effect of total flavones of Choerospondias axillaries on ischemia/reperfusion-induced myocardial infarction-related MAPK signaling pathway.

    abstract::Choerospondias axillaris (Guangzao) is a medicinal plant used in Mongolia, and its fruit is commonly used for the treatment of cardiovascular diseases in clinic. The constituents responsible for this effect are always conceded to be the total flavonoids of C. axillaries (TFC). The present study was to evaluate the pre...

    journal_title:Cardiovascular toxicology

    pub_type: 杂志文章

    doi:10.1007/s12012-013-9238-7

    authors: Li C,He J,Gao Y,Xing Y,Hou J,Tian J

    更新日期:2014-06-01 00:00:00

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